Transepithelial immunomodulation by cholera toxin and non-toxic derivatives.

abstract：:Six adjuvant formulations were compared for their ability to potentiate the primary and memory antibody responses in mice to three companion animal vaccine immunogens--feline leukemia virus (FeLV), feline immunodeficiency virus (FIV), and a recombinantly-derived heartworm antigen. The combination of a novel bacterial ...

journal_title：Vaccine

authors： Usinger WR

更新日期：1997-12-01 00:00:00

abstract：BACKGROUND:Following a recommendation by the World Health Organization, Madagascar introduced rotavirus vaccine in 2014. Though national rotavirus vaccine coverage has remained <80%, rotavirus hospitalizations declined by 78%. Gavi, the Vaccine Alliance, has provided financial support for rotavirus vaccine, however the...

journal_title：Vaccine

authors： Burnett E,Rahajamanana VL,Raboba JL,Weldegebriel G,Vuo Masembe Y,Mwenda JM,Parashar UD,Tate JE,Robinson AL

更新日期：2020-11-03 00:00:00

abstract：:Measles remains a major cause of worldwide infant mortality despite the use of current live attenuated vaccines. New approaches to measles virus (MV) vaccine development are critical to interrupt the spread of MV. In this study, we report the results using a DNA vaccine expressing a fusion of the measles hemagglutinin...

journal_title：Vaccine

authors： Green TD,Newton BR,Rota PA,Xu Y,Robinson HL,Ross TM

更新日期：2001-10-12 00:00:00

abstract：:Designation as a Category B biothreat agent has propelled Coxiella burnetii from a relatively obscure, underappreciated, "niche" microorganism on the periphery of bacteriology, to one of possibly great consequence if actually used in acts of bioterrorism. Advances in the study of this microorganism proceeded slowly, p...

journal_title：Vaccine

authors： Waag DM

更新日期：2007-10-16 00:00:00

abstract：:Our development of genetic immunization (unfortunately named 'DNA'-immunization at times) seems to have great promise as a vaccine delivery system. However, one is still left with the often formidable problem of discovering what gene of the pathogen to include in the genetic immunization vector. The is particularly a ...

journal_title：Vaccine

authors： Johnston SA,Barry MA

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Vaccinations are an effective choice to stop disease outbreaks, including COVID-19. There is little research on individuals' COVID-19 vaccination decision-making. OBJECTIVE:We aimed to determine individual preferences for COVID-19 vaccinations in China, and to assess the factors influencing vaccination deci...

journal_title：Vaccine

authors： Leng A,Maitland E,Wang S,Nicholas S,Liu R,Wang J

更新日期：2021-01-08 00:00:00

abstract：:Based on the reactivities of monoclonal antibodies, we previously reported that 25 Japanese encephalitis (JE) virus strains fell into five antigenic groups: Nakayama, Beijing-1, Kamiyama, 691004 and Muar. In the present study, we produced monoclonal antibodies against the Beijing-1 strain and obtained the Beijing-1 gr...

journal_title：Vaccine

authors： Satake Y,Hasegawa H,Yoshida M,Kobayashi Y

更新日期：1994-06-01 00:00:00

abstract：:The assignment of infectious potency to test articles of adenovirus has been conducted mainly using classical end-point dilution methods, which rely on virus induced cytopathology to reveal the presence of infectious virus. These assays suffer the disadvantages of labor intensity, duration, throughput restriction and ...

journal_title：Vaccine

authors： Wang F,Puddy AC,Mathis BC,Montalvo AG,Louis AA,McMackin JL,Xu J,Zhang Y,Tan CY,Schofield TL,Wolf JJ,Lewis JA

更新日期：2005-08-22 00:00:00

abstract：OBJECTIVE:This study aimed to explore attitudes to human papillomavirus (HPV) vaccination and reasons for accepting or declining the vaccine in the British Jewish community. METHODS:A qualitative approach was used to explore maternal attitudes towards HPV vaccination. Participants were mothers of girls who had been of...

journal_title：Vaccine

authors： Gordon D,Waller J,Marlow LA

更新日期：2011-10-06 00:00:00

abstract：:We demonstrated earlier that immunization with recombinant Leptospira immunoglobulin like protein A (LigA) induced significant protection against virulent Leptospira interrogans serovar Pomona challenge in hamsters. However, the protective immune mechanism remains unclear. In the present study we demonstrated the prot...

journal_title：Vaccine

authors： Faisal SM,Yan W,Chen CS,Palaniappan RU,McDonough SP,Chang YF

更新日期：2008-01-10 00:00:00

abstract：:An ELISA-immunocapture assay was developed for quantification of influenza neuraminidases (N2 and B), with a sensitivity about 10 ng neuramidase(NA)/ml. This sensitive and specific assay was applied to several trivalent vaccine preparations (1997/1998 and 1998/1999). It was shown capable to detect 3.5-6.9 microg NA/ml...

journal_title：Vaccine

authors： Aymard M

更新日期：2002-05-15 00:00:00

abstract：:We sought to measure the anxiety felt by parents at the time of entry into a randomized controlled vaccine trial, and to determine if anxiety level was associated with parental demographic variables or past experience. The children were 2-month-old infants entering a randomized controlled clinical trial (RCT) of a dip...

journal_title：Vaccine

authors： Langley JM,Halperin SA,Smith B

更新日期：2003-09-08 00:00:00

abstract：:The Vaccine Adverse Event Reporting System (VAERS) is the US passive surveillance system monitoring vaccine safety. A major limitation of VAERS is the lack of denominator data (number of doses of administered vaccine), an element necessary for calculating reporting rates. Empirical Bayesian data mining, a data analysi...

journal_title：Vaccine

authors： Niu MT,Erwin DE,Braun MM

更新日期：2001-09-14 00:00:00

abstract：BACKGROUND:Invasive pneumococcal disease and respiratory tract infections are both frequent and severe in patients with systemic lupus erythematosus (SLE). This study aimed to compare the immunological efficacy and safety of pneumococcal vaccination with the 23-valent polysaccharide (PPS) vaccine alone to a sequential ...

journal_title：Vaccine

authors： Grabar S,Groh M,Bahuaud M,Le Guern V,Costedoat-Chalumeau N,Mathian A,Hanslik T,Guillevin L,Batteux F,Launay O,VACCILUP study group.

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Alternative methods for influenza vaccine production are needed to ensure adequate supplies. METHODS:Healthy adults 50-64 years were assigned randomly to receive one intramuscular injection of trivalent recombinant hemagglutinin (rHA) or U.S. licensed trivalent inactivated vaccine (TIV) containing H1, H3 an...

journal_title：Vaccine

authors： Baxter R,Patriarca PA,Ensor K,Izikson R,Goldenthal KL,Cox MM

更新日期：2011-03-09 00:00:00

abstract：BACKGROUND:Development of influenza vaccines that do not use embryonated eggs as the substrate for vaccine production is a high priority. We conducted this study to determine the protective efficacy a recombinant, baculovirus-expressed seasonal trivalent influenza virus hemagglutinin (rHA0) vaccine (FluBlok(®)). METHO...

journal_title：Vaccine

authors： Treanor JJ,El Sahly H,King J,Graham I,Izikson R,Kohberger R,Patriarca P,Cox M

更新日期：2011-10-13 00:00:00

abstract：BACKGROUND:We have previously developed a recombinant avian avulavirus serotype 10 (rAAvV-10/HA) expressing the hemagglutinin (HA) gene of a highly pathogenic avian influenza virus (HPAIV) as an emergency vaccine for poultry. rAAvV-10/HA can overcome the activity of the anti-AAvV-1 (Newcastle disease virus) antibody ac...

journal_title：Vaccine

authors： Tsunekuni R,Tanikawa T,Nakaya T,Saito T

更新日期：2020-01-22 00:00:00

abstract：:Real, perceived and unknown adverse events secondary to vaccinations are a source of concern for care providers of children. In the USA large linked databases have provided helpful information regarding the safety of vaccines. Very little prospectively collected data on vaccine safety is available from resource poor c...

journal_title：Vaccine

authors： Ali M,Canh DG,Clemens JD,Park JK,von Seidlein L,Thiem VD,Tho le H,Trach DD

更新日期：2003-04-02 00:00:00

abstract：BACKGROUND:Protein-polysaccharide conjugate vaccines such as Haemophilus influenzae type b (Hib), meningococcal, and pneumococcal vaccine, induce immunological memory and longer lasting protection than plain polysaccharide vaccines. The most common proteins used as carriers are tetanus toxoid (TT) and cross reacting ma...

journal_title：Vaccine

authors： Voysey M,Sadarangani M,Clutterbuck E,Bolgiano B,Pollard AJ

更新日期：2016-07-25 00:00:00

abstract：:In July 1999, the Department of Health launched a campaign to immunise all children aged from 0-17 years with a new vaccine giving protection against meningococcal group C infection. Following the campaign, a survey of Immunisation Co-ordinators in England was conducted to identify strengths and weaknesses of the camp...

journal_title：Vaccine

authors： Lansley M,Bedford H

更新日期：2003-06-20 00:00:00

abstract：OBJECTIVE:Evaluating HIV-1 specific T-cell response in African populations is sometimes compromised by extensive virus diversity and paucity of non-clade B reagents. We evaluated whether consensus group M (ConM) peptides could serve as comparable substitutes for detecting immune responses in clade A and clade D HIV-1 i...

journal_title：Vaccine

authors： Mugaba S,Nakiboneka R,Nanyonjo M,Bugembe-Lule D,Kaddu I,Nanteza B,Tweyongyere R,Kaleebu P,Serwanga J

更新日期：2014-06-24 00:00:00

abstract：:General vaccination with the 7-valent pneumococcal conjugate vaccine was recommended in Germany in July 2006 for all children <2 years. The proportion of reported invasive pneumococcal disease (IPD) caused by vaccine serotypes before vaccine introduction was considerably lower than in the US. We report data from natio...

journal_title：Vaccine

authors： Rückinger S,van der Linden M,Reinert RR,von Kries R,Burckhardt F,Siedler A

更新日期：2009-06-24 00:00:00

abstract：:The identification of new vaccine candidates for leptospirosis is of great interest. This paper describes the identification of two homologous immunogenic proteins, LigA-m and LigB-m, of Leptospira interrogans serovar manilae strain UP-MMC-NIID, which show strong similarity with LigA found recently in L. interrogans s...

journal_title：Vaccine

authors： Koizumi N,Watanabe H

更新日期：2004-03-29 00:00:00

abstract：:Three separate studies were undertaken in HIV-1 uninfected persons to determine if the adjuvant QS-21 improves the magnitude or kinetics of immune responses induced by recombinant soluble gp120 HIV-1(MN) protein (rsgp120) immunization. The QS-21 was administered at two doses (50 and 100 microg), either alone or in com...

journal_title：Vaccine

authors： Evans TG,McElrath MJ,Matthews T,Montefiori D,Weinhold K,Wolff M,Keefer MC,Kallas EG,Corey L,Gorse GJ,Belshe R,Graham BS,Spearman PW,Schwartz D,Mulligan MJ,Goepfert P,Fast P,Berman P,Powell M,Francis D,NIAID AIDS V

更新日期：2001-02-28 00:00:00

abstract：:Vaccine exposure to temperatures below recommended ranges in the cold chain may decrease vaccine potency of freeze-sensitive vaccines leading to a loss of vaccine investments and potentially places children at risk of contracting vaccine preventable illnesses. This literature review is an update to one previously publ...

journal_title：Vaccine

authors： Hanson CM,George AM,Sawadogo A,Schreiber B

更新日期：2017-04-19 00:00:00

abstract：:Following a landmark clinical trial, the vaccine against Haemophilus influenzae type b (Hib) was introduced in The Gambia in 1997. Whilst the immunogenicity of this vaccine is well established subsequent to the doses administered under the EPI schedule, little data exists assessing longevity of protection, using serol...

journal_title：Vaccine

authors： Idoko OT,Roberts E,Cox M,Jafali J,Njie-Jobe J,Mackenzie G,Ota MO,Kampmann B

更新日期：2014-08-06 00:00:00

abstract：:Vaccines are urgently needed to elicit immunity to different influenza virus strains. DNA vaccines can elicit partial protective immunity, however their efficacy requires improvement. We assessed the capacity of individual type I IFN multigene family members as subtype transgenes to abrogate influenza virus replicatio...

journal_title：Vaccine

authors： James CM,Abdad MY,Mansfield JP,Jacobsen HK,Vind AR,Stumbles PA,Bartlett EJ

更新日期：2007-02-26 00:00:00

abstract：:Three proteins of PE and PPE families of Mycobacterium tuberculosis were evaluated for their ability to induce T cell responses in mice. To enhance immunity induced by protein immunization, we tested the efficacy of adjuvant Ribi (monophosphoryl lipid A+TDM), along with three proteins of the PE/PPE family. Balb/c mice...

journal_title：Vaccine

authors： Chaitra MG,Nayak R,Shaila MS

更新日期：2007-10-10 00:00:00

abstract：:Vaccines are needed to control zoonotic Schistosoma japonicum infection and several vaccine candidates have now been identified. Two of these (Sj28GST and Sj23) have shown particular promise in sheep when injected with Freund's adjuvants. The objective of the present work was to find a vaccine formulation which may ha...

journal_title：Vaccine

authors： Shi F,Zhang Y,Ye P,Lin J,Cai Y,Shen W,Bickle QD,Taylor MG

更新日期：2001-11-12 00:00:00

abstract：:Immunisation is one of the corner stones of public health. Most health care consumers see the health care worker as their major source of information on immunisation and vaccine safety. Doctors, nurses and midwives should be appropriately and timely trained for that role. Within the Vaccine Safety, Attitudes, Training...

journal_title：Vaccine

authors： Vorsters A,Tack S,Hendrickx G,Vladimirova N,Bonanni P,Pistol A,Metlicar T,Pasquin MJ,Mayer MA,Aronsson B,Heijbel H,Van Damme P

更新日期：2010-02-25 00:00:00