An experimental vaccine cocktail for Plasmodium falciparum malaria.

abstract：:We hypothesized that the ability of BCG vaccination to protect against Mycobacterium tuberculosis is less in hosts exposed to chronic helminthes infection compared to unexposed individuals. To test this hypothesis we evaluated the efficacy of BCG vaccination in protecting against M. tuberculosis challenge in Schistoso...

journal_title：Vaccine

authors： Elias D,Akuffo H,Pawlowski A,Haile M,Schön T,Britton S

更新日期：2005-02-03 00:00:00

abstract：INTRODUCTION:The Global Vaccine Action Plan and the Regional Immunization Action Plan of the Americas call for countries to improve immunization data quality. Immunization information systems, particularly electronic immunization registries (EIRs), can help to facilitate program management and increase coverage. Howeve...

journal_title：Vaccine

authors： Trumbo SP,Contreras M,García AGF,Díaz FAE,Gómez M,Carrión V,Ruiz KJP,Aquije R,Danovaro-Holliday MC,Velandia-González M

更新日期：2018-11-29 00:00:00

abstract：:A devastating disease spread by mosquitoes with high-efficiency, malaria imposes an enormous burden for which no licensed vaccine currently exists. Although the genome complexity of the parasite has made vaccine development tenuous, an effective malaria vaccine would be a valuable tool for control, elimination and eve...

journal_title：Vaccine

authors： Palacpac NM,Arisue N,Tougan T,Ishii KJ,Horii T

更新日期：2011-08-11 00:00:00

abstract：:H5N1, highly pathogenic avian influenza poses, a threat to animal and human health. Rapid changes in H5N1 viruses require periodic reformulation of the conventional strain-matched vaccines, thus emphasizing the need for a broadly protective influenza vaccine. Here, we constructed BV-Dual-3M2e-LTB, a recombinant baculo...

journal_title：Vaccine

authors： Zhang J,Fan HY,Zhang Z,Zhang J,Zhang J,Huang JN,Ye Y,Liao M

更新日期：2016-01-27 00:00:00

abstract：:Longitudinal serum samples were collected from 542 children that had participated in a Swedish pertussis vaccine trial 1992-1995 [Gustafsson L, Hallander HO, Olin P, Reizenstein E, Storsaeter J. A controlled trial of a two-component acellular, a five-component acellular, and a whole-cell pertussis vaccine. N Engl J Me...

journal_title：Vaccine

authors： Hallander HO,Gustafsson L,Ljungman M,Storsaeter J

更新日期：2005-11-16 00:00:00

abstract：:Using HIV-1 envelope protein (Env)-based immunogens that closely mimic the conformation of functional HIV-1 Envs and represent the isolates prevalent in relevant geographical region is considered a rational approach towards developing HIV vaccine. We recently reported that like clade B Env, JRFL, membrane bound Indian...

journal_title：Vaccine

authors： Shrivastava T,Samal S,Tyagi AK,Goswami S,Kumar N,Ozorowski G,Ward AB,Chakrabarti BK

更新日期：2018-03-14 00:00:00

abstract：:Across the developing world peste des petits ruminants virus places a huge disease burden on agriculture, primarily affecting the production of small ruminant. The disease is most effectively controlled by vaccinating sheep and goats with live attenuated vaccines that provide lifelong immunity. However, the current va...

journal_title：Vaccine

authors： Muniraju M,Mahapatra M,Buczkowski H,Batten C,Banyard AC,Parida S

更新日期：2015-01-09 00:00:00

abstract：:P25 is a major surface protein of Plasmodium ookinetes. Antibodies against P25 prevent the formation of oocysts in the mosquito and thereby block transmission of the parasite through an endemic population. Plasmodium vivax transmission-blocking vaccines based on Pv25 have undergone human trials and inhibit transmissio...

journal_title：Vaccine

authors： Ramjanee S,Robertson JS,Franke-Fayard B,Sinha R,Waters AP,Janse CJ,Wu Y,Blagborough AM,Saul A,Sinden RE

更新日期：2007-01-15 00:00:00

abstract：:As part of a larger study exploring how European citizens' balance issues of public and private interest and the extent to which they are prepared to accept State intervention on a range of public health issues, focus group participants were asked whether childhood immunisation should be a matter of parental choice or...

journal_title：Vaccine

authors： Moran N,Shickle D,Richardson E

更新日期：2008-01-17 00:00:00

abstract：:Helper T cel lines specific for influenza virus were established by continuous culture of Mem 71-Bel (H3) virus-immune spleen cells in the presence of virus and antigen-presenting cells and their specificity assessed in proliferation experiments. A line stimulated in vitro with Mem 71-Bel virus was able to proliferate...

journal_title：Vaccine

authors： Katz JM,Brown LE,Ffrench RA,White DO

更新日期：1985-09-01 00:00:00

abstract：:We report influenza vaccination coverage in target groups for the 2010-2011 influenza season, one year after the A(H1N1) pandemic. Data were collected through a one-stage cross-sectional national random telephone survey conducted in January 2011 among a sample of the population of mainland France connected to a land t...

journal_title：Vaccine

authors： Guthmann JP,Fonteneau L,Bonmarin I,Lévy-Bruhl D

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:In 2008, China introduced live, attenuated hepatitis A vaccine (L-HepA, licensed in 1992) and inactivated hepatitis A vaccine (I-HepA, licensed in 2002) nationwide, and is currently the only country using L-HepA in routine immunization. We assessed seropositivity and its duration following vaccination, safet...

journal_title：Vaccine

authors： Xiaojin S,Rodewald LE,Guomin Z,Hui Z,Ning M,Fuzhen W,Zundong Y

更新日期：2020-12-14 00:00:00

abstract：:Dengue is one of the most important mosquito-borne viral disease causing dengue fever and/or dengue shock syndrome/haemorrhagic fever. In some reports, the non-structural protein 1 (NS1) has been identified as a promising antigen for the development of vaccines against dengue virus (DENV). Apparently, it can elicit a ...

journal_title：Vaccine

authors： Costa SM,Freire MS,Alves AM

更新日期：2006-05-22 00:00:00

abstract：:Endospores of the Gram-positive bacterium, Bacillus subtilis, have been used successfully for delivery of antigens where the immunogen is expressed on the spore surface. In this work the spore has been engineered to deliver antigens to the cytoplasm of macrophages by expressing listeriolysin O (LLO) or a derivative, L...

journal_title：Vaccine

authors： Huang JM,La Ragione RM,Cooley WA,Todryk S,Cutting SM

更新日期：2008-11-11 00:00:00

abstract：:A randomized, double-blind, controlled clinical trial was conducted to evaluate the efficacy and safety of CJ-50300, a newly developed cell culture-derived smallpox vaccine, and to determine its minimum effective dose. The overall rates of cutaneous "take" reaction and humoral and cellular immunogenicity in CJ-50300 v...

journal_title：Vaccine

authors： Jang HC,Kim CJ,Kim KH,Lee KH,Byun YH,Seong BL,Saletti G,Czerkinsky C,Park WB,Park SW,Kim HB,Kim NJ,Oh MD

更新日期：2010-08-16 00:00:00

abstract：INTRODUCTION:Determining vaccine responsiveness is challenging in immune compromised individuals. The microbead array (MBA) assay is a rapid, inexpensive test for evaluating influenza vaccine immunogenicity. MBA performance was compared to hemagglutination inhibition assay (HAI) utilizing HIV seropositive vaccine recip...

journal_title：Vaccine

authors： Thorne A,Chowdhury F,Singer J,Keynan Y,Fowke KR,Cooper C,CIHR Canadian HIV Trials Network (CTN) Influenza Vaccine Research Group.

更新日期：2016-06-30 00:00:00

abstract：:Although the USA is considered an area of 'low' endemicity for hepatitis B infection, the incidence of new cases, the prevalence of carriers, and the burden of acute and chronic disease place hepatitis B among the most important communicable diseases. It is estimated that 300,000 new cases of hepatitis B infection occ...

journal_title：Vaccine

authors： Kane M

更新日期：1995-01-01 00:00:00

abstract：:We developed a novel procedure to evoke anti-aggregating beta-amyloid (Abeta) antibodies, using filamentous phages displaying only four amino acids EFRH of the beta-amyloid peptide (AbetaP). This epitope was found to be the main regulatory site for fibril formation. For the first time, effective auto-antibodies have b...

journal_title：Vaccine

authors： Frenkel D,Kariv N,Solomon B

更新日期：2001-03-21 00:00:00

abstract：:Prevention of lifestyle-related diseases and promotion of physical and mental well-being in adolescents require an understanding of how life situations place adolescents at risk. The most important risk factors for hepatitis B virus (HBV) infection are sexual activity with more than one partner and injecting drug use....

journal_title：Vaccine

authors： Meheus A

更新日期：2000-02-18 00:00:00

abstract：:A prospective, randomised, controlled observer-blind trial measuring the efficacy and immunogenicity of trivalent influenza vaccine (TIV) and the immunogenicity of quadrivalent meningococcal conjugate vaccine (MCV) in pregnant women and their infants up to 6 months of age was conducted in Mali. Here we reported the im...

journal_title：Vaccine

authors： Findlow H,Tapia MD,Sow SO,Haidara FC,Coulibaly F,Keita AM,Diallo F,Doumbia M,Traore A,Schluterman N,Clark DA,Borrow R,Levine MM

更新日期：2019-04-24 00:00:00

abstract：:A phase II safety and immunogenicity study of an oral-formalin inactivated enterotoxigenic Escherichia coli (ETEC) vaccine containing six colonization factors (CFA/I, CS1, CS2, CS3, CS4, CS5) and 1mg of recombinant cholera toxin B subunit (the CF-BS-ETEC vaccine) was carried out in an urban slum of Dhaka city in Bangl...

journal_title：Vaccine

authors： Qadri F,Ahmed T,Ahmed F,Bradley Sack R,Sack DA,Svennerholm AM

更新日期：2003-06-02 00:00:00

abstract：:One of the greatest challenges to HCV vaccine development is the induction of effective immune responses using recombinant proteins or vectors. In order to better understand which vaccine-induced antibodies contribute to neutralization of HCV the quality of polyclonal anti-E1E2 antibody responses in immunized mice and...

journal_title：Vaccine

authors： Kachko A,Kochneva G,Sivolobova G,Grazhdantseva A,Lupan T,Zubkova I,Wells F,Merchlinsky M,Williams O,Watanabe H,Ivanova A,Shvalov A,Loktev V,Netesov S,Major ME

更新日期：2011-12-09 00:00:00

abstract：:We performed a genome-wide association study (GWAS) of antibody levels in a multi-ethnic group of 1071 healthy smallpox vaccine recipients. In Caucasians, the most prominent association was found with promoter SNP rs10489759 in the LOC647132 pseudogene on chromosome 1 (p=7.77×10(-8)). In African-Americans, we identifi...

journal_title：Vaccine

authors： Ovsyannikova IG,Kennedy RB,O'Byrne M,Jacobson RM,Pankratz VS,Poland GA

更新日期：2012-06-13 00:00:00

abstract：BACKGROUND:Current national immunisation schedules differ between countries in terms of vaccine formulation, timing of vaccinations and immunisation programme funding and co-ordination. As a result, some HIV infected paediatric population may be left susceptible to vaccine preventable infections. Vaccines used in healt...

journal_title：Vaccine

authors： Bamford A,Manno EC,Mellado MJ,Spoulou V,Marques L,Scherpbier HJ,Niehues T,Oldakowska A,Rossi P,Palma P,PENTA-vac Group.

更新日期：2016-11-04 00:00:00

abstract：BACKGROUND:Elimination of congenital rubella syndrome depends not only on effective childhood immunization but also on the identification and immunization of rubella susceptible women. We assessed rubella susceptibility among pregnant women and evaluated the adherence and response to postpartum immunization with measle...

journal_title：Vaccine

authors： Vilajeliu A,García-Basteiro AL,Valencia S,Barreales S,Oliveras L,Calvente V,Goncé A,Bayas JM

更新日期：2015-04-08 00:00:00

abstract：:Cholera is a potentially lethal diarrhea disease caused by the gram-negative bacterium Vibrio cholerae. The need for an effective cholera vaccine is clearly indicated but the challenges of eliciting both systemic and mucosal immune responses remains a significant challenge. In the current report, we discovered that a ...

journal_title：Vaccine

authors： Xu G,Wang S,Zhuang L,Hackett A,Gu L,Zhang L,Zhang C,Wang H,Huang Z,Lu S

更新日期：2009-06-12 00:00:00

abstract：:Seneca Valley virus (SVV) infection in pigs is associated with porcine idiopathic vesicular disease (PIVD). Outbreaks of SVV infection in pig herds have been reported in several Asia and Americas countries. Recently, a series of outbreaks of SVV infection occurred in China, Canada, Thailand and the United States. Howe...

journal_title：Vaccine

authors： Yang F,Zhu Z,Cao W,Liu H,Zhang K,Tian H,Liu X,Zheng H

更新日期：2018-02-01 00:00:00

abstract：:Montanide ISA 720 is an experimental adjuvant, formulated as water-in-oil emulsions, that induces high antibody titers in several animal species. It has been used in human vaccine trials with malaria and HIV vaccines. The heightened response is likely due, in part, to the formation of a depot at the injection site. Ho...

journal_title：Vaccine

authors： Miles AP,McClellan HA,Rausch KM,Zhu D,Whitmore MD,Singh S,Martin LB,Wu Y,Giersing BK,Stowers AW,Long CA,Saul A

更新日期：2005-03-31 00:00:00

abstract：:Four different preparations of hepatitis B antigen (HBsAg) were tested in parallel with respect to their ability to elicit anti-HBs in guinea-pigs. We compared the effect of low doses (5 micrograms single dose and 30 micrograms total amount) of human plasma derived and recombinant HBsAg, in purified forms or prepared ...

journal_title：Vaccine

authors： Valinger Z,Tresćec A,Tomasić J

更新日期：1990-12-01 00:00:00

abstract：BACKGROUND:To support vaccine decision-making we estimated from the societal perspective the potential health impact and costs averted through immunization with three vaccines - Haemophilus influenzae type b (Hib), pneumococcal conjugate vaccine (PCV) and rotavirus vaccine (RVV). METHODS:Based on variability in diseas...

journal_title：Vaccine

authors： Constenla D,Liu T

更新日期：2019-12-10 00:00:00