NMDA-dependent induction of long-term potentiation in afferent and association fiber systems of piriform cortex in vitro.

abstract：:Gonadal steroids are thought to act by activation of the genome following cytoplasmic binding, translocation of the hormone--receptor complex to the nucleus and chromatin binding at specific acceptor sites. This study examined the kinetics of chromatin binding of estradiol by hypothalamic and cortical cells of adult g...

journal_title：Brain research

authors： Whalen RE,Olsen KL

更新日期：1978-08-18 00:00:00

abstract：:We have developed a cell culture system for the rat suprachiasmatic nucleus, in which a clear circadian oscillation of vasopressin release was observed. Using this culture system, the effect of anisomycin, an inhibitor of protein synthesis, on the circadian rhythm was studied. A phase-delay of more than 15 h could be ...

journal_title：Brain research

authors： Watanabe K,Katagai T,Ishida N,Yamaoka S

更新日期：1995-07-03 00:00:00

abstract：:Prostaglandin E2 (PGE2) is a lipid mediator which plays a role in the generation of inflammatory and neuropathic pain. In the peripheral nervous system, PGE2 sensitizes nociceptive afferent neurons through E-prostanoid (EP) receptors. In the central nervous system, PGE2 modulates pain sensitivity and contributes to th...

journal_title：Brain research

authors： Kanda H,Kobayashi K,Yamanaka H,Okubo M,Dai Y,Noguchi K

更新日期：2021-01-01 00:00:00

abstract：:Given that relatively little is known regarding the central control of brown adipose tissue (BAT)-mediated thermogenesis the present study assessed whether the direct pharmacological stimulation of beta- or alpha-adrenergic receptors located on the brown adipocytes would result in a typical thermogenic response follow...

journal_title：Brain research

authors： Fyda DM,Cooper KE,Veale WL

更新日期：1991-04-19 00:00:00

abstract：:Experiments were done in chloralose anesthetized, paralyzed and artificially ventilated cats to identify single units in ventrolateral medulla (VLM) projecting directly to the intermediate gray (IG) region of the upper thoracic cord and responding to inputs from pressor sites in the anterior lateral hypothalamus (Hla)...

journal_title：Brain research

authors： Ciriello J,Caverson MM,Calaresu FR

更新日期：1985-11-11 00:00:00

abstract：:Entopeduncular nucleus (EPN) cells which project to thalamic and non-thalamic sites were identified by antidromic discharge. Each population of cells, projecting to the ventral anterior nucleus of the thalamus (VA), centrum medianum (CM), the lateral habenula (LHB), and the pedunculopontine nucleus (PP), was distribut...

journal_title：Brain research

authors： Larsen KD,Sutin J

更新日期：1978-11-17 00:00:00

abstract：:The postnatal development of cat triceps surae gamma-motoneurones, retrogradely labelled with horseradish peroxidase (HRP), was studied light and electron microscopically. The mean diameter of the cell bodies of the gamma-motoneurones increased by about 25% from birth to the adult stage, which was much less than the i...

journal_title：Brain research

authors： Arvidsson U,Svedlund J,Lagerbäck PA,Cullheim S

更新日期：1987-12-15 00:00:00

abstract：:Elevations in the plasma levels of glucocorticoids are associated with cognitive impairments that have been ascribed to loss of neurons in the hippocampal formation. However, recent studies have strongly challenged this view. In order to clarify this issue, we have employed for the first time the optical fractionator ...

journal_title：Brain research

authors： Sousa N,Madeira MD,Paula-Barbosa MM

更新日期：1998-06-01 00:00:00

abstract：:Reduced neuronal plasticity in the striatum, hippocampus, and neocortex is a common feature of transgenic mouse models of Huntington's disease (HD). Doublecortin (DCX) and polysialylated neural cell adhesion molecule (PSA-NCAM) are associated with structural plasticity in the adult mammalian brain, are markers of newl...

journal_title：Brain research

authors： Lazic SE,Goodman AO,Grote HE,Blakemore C,Morton AJ,Hannan AJ,van Dellen A,Barker RA

更新日期：2007-06-02 00:00:00

abstract：:We investigated the effect of Cerebrospinal Fluid (CSF) from sporadic Amyotrophic Lateral Sclerosis patients (SALS-CSF) on motor neuron-like cells to delineate the pathomechanism of SALS. Exposure of NSC-34 cells to SALS-CSF caused lower viability, reduction in differentiation and enhanced lactate dehydrogenase activi...

journal_title：Brain research

authors： Vijayalakshmi K,Alladi PA,Sathyaprabha TN,Subramaniam JR,Nalini A,Raju TR

更新日期：2009-03-31 00:00:00

abstract：:Electrical stimulation of the sural nerve (SN) revealed input from sural nerve afferents to L6 and L7 dorsal horn neurons that were not apparent using natural mechanical stimuli, especially in cells with variable latency responses to SN stimulation. Nearly all (31/32) cells that had reliable, fixed latency responses t...

journal_title：Brain research

authors： Pubols LM,Foglesong ME,Vahle-Hinz C

更新日期：1986-04-16 00:00:00

abstract：:To characterize optical responses (ORs) evoked by white matter (WM) stimulation in slices of rat visual cortex (VC) stained with voltage sensitive dyes, time course of ORs in each layer was investigated by recording ORs with a linearly aligned photodiode array, and the spatial patterns of the ORs at specified time aft...

journal_title：Brain research

authors： Tanifuji M,Yamanaka A,Sunaba R,Terakawa S,Toyama K

更新日期：1996-10-28 00:00:00

abstract：:The activity of choline kinase (CK) was examined in the rat superior cervical ganglion (SCG) during development and following postganglionic axotomy. The highest specific enzyme activity (nmol phosphorylcholine/mg protein/h) 52 +/- 8, is observed 5 d before birth, then it rapidly decreases by about 50%, reaching at th...

journal_title：Brain research

authors： Gilad GM,Gilad VH

更新日期：1981-09-14 00:00:00

abstract：:The acute effects of ethanol on the gamma-aminobutyric acid (GABA)-activated current were studied with the rat dorsal root ganglion neurons in primary culture using the whole-cell patch-clamp technique. GABA produced an inward chloride current, which was composed of an initial transient and a subsequent sustained phas...

journal_title：Brain research

authors： Nishio M,Narahashi T

更新日期：1990-06-04 00:00:00

abstract：:Peroxisome proliferator-activated receptors (PPARs) are nuclear receptors and are considered promising therapeutic targets in several neurodegenerative diseases. A number of PPAR agonists have been shown to have neuroprotective properties in the presence of oxidative stress, neuroinflammatory response, and apoptosis i...

journal_title：Brain research

authors： Lee Y,Cho JH,Lee S,Lee W,Chang SC,Chung HY,Moon HR,Lee J

更新日期：2019-02-01 00:00:00

abstract：:Close to 20% of the patients infected with the AIDS virus develops neurological deficit; eventhough HIV does not invade neurons. Consistently with the neurological deficit, HIV(+) subjects show abnormalities in brainstem auditory and visual evoked potentials (BSAEP and VEP) and in sleep patterns. The HIV-derived glyco...

journal_title：Brain research

authors： Prospéro-García O,Huitrón-Resendiz S,Casalman SC,Sánchez-Alavez M,Díaz-Ruiz O,Navarro L,Lerner DL,Phillips TR,Elder JH,Henriksen SJ

更新日期：1999-07-31 00:00:00

abstract：:Humans flexibly adapt their behavior using feedback from their environment. This ability is impaired in old age, but recent research suggests this mainly concerns processing of negative feedback and that positive feedback might be spared. The aim of this study was to test this idea of an age-related positivity bias ag...

journal_title：Brain research

authors： Ferdinand NK

更新日期：2019-08-15 00:00:00

abstract：:The postnatal development of soma size and cytochrome oxidase activity was examined in the perigeniculate nucleus (PGN) and reticular nucleus of the thalamus (RNT). Neurons in the PGN and RNT exhibited a rapid increase in soma size between 2 and 4 weeks of age. During this period of cell growth there is an increase in...

journal_title：Brain research

authors： Murakami DM,Condo GJ,Wilson PD

更新日期：1987-10-01 00:00:00

abstract：:A study was undertaken of the role of the external lateral parabrachial subnucleus (PBNLe) in flavor preferences induced by the intragastric administration of predigested/cephalic food. These preferences were developed using two different learning procedures, concurrent and sequential. In the concurrent procedure, two...

journal_title：Brain research

authors： Zafra MA,Simón MJ,Molina F,Puerto A

更新日期：2002-09-20 00:00:00

abstract：:The effect of an 8% casein and a control 25% casein diet on the granule cells in the dorsal blade of the dentate gyrus of the rat hippocampal formation was studied at 30, 90 and 220 days of age. Female rats were fed either an 8% or 25% casein diet 5 weeks prior to conception and the litters were maintained on these re...

journal_title：Brain research

authors： Cintra L,Díaz-Cintra S,Galván A,Kemper T,Morgane PJ

更新日期：1990-11-05 00:00:00

abstract：:The purpose of this study was to examine whether endothelium-mediated dilation is responsible for the cortical hyperemia that occurs during cortical spreading depression (CSD) in rats using three different approaches. The first approach taken was the acute pharmacological inhibition of the predominant endothelium-cent...

journal_title：Brain research

authors： Shimizu K,Miller AW,Erdös B,Bari F,Busija DW

更新日期：2002-02-22 00:00:00

abstract：:The effects of dopamine on glutamate-induced cytotoxicity were examined using the primary cultures of rat striatal neurons. Cell viability was significantly reduced by exposure of cultures to glutamate or kainate for 24 h. In contrast, similar application of N-methyl-D-aspartate (NMDA) or alpha-amino-3-hydroxy-5-methy...

journal_title：Brain research

authors： Amano T,Ujihara H,Matsubayashi H,Sasa M,Yokota T,Tamura Y,Akaike A

更新日期：1994-08-29 00:00:00

abstract：:cAMP-dependent regulation of the steady-state mRNA levels for the ECM components, laminin A, B1 and B2 chains, collagen types I, III and IV were examined by Northern blot analysis in cultured rat Schwann cells. ECM mRNAs of laminin B1 chain and collagen types I and IV were expressed at high levels in the control Schwa...

journal_title：Brain research

authors： Yamamoto M,Sobue G,Li M,Mitsuma T,Kimata K,Yamada Y

更新日期：1994-08-08 00:00:00

abstract：:The capacity of the dopaminergic nerve system to reinnervate the denervated adult striatum was analyzed in a model of partial 6-hydroxydopamine-induced unilateral lesion of rat substantia nigra pars compacta. Sprouting of dopaminergic fibers entering the ventrolateral part of the striatum from a narrow zone of the ext...

journal_title：Brain research

authors： Blanchard V,Anglade P,Dziewczapolski G,Savasta M,Agid Y,Raisman-Vozari R

更新日期：1996-02-19 00:00:00

abstract：:Mapping studies with central drug injections in the hungry rat have identified the perifornical lateral hypothalamus as being uniquely sensitive to the feeding suppressive effects of exogenous dopamine, as well as anorexic drugs which release endogenous catecholamines. In the present study, the hypothalamic dopamine-r...

journal_title：Brain research

authors： Leibowitz SF,Rossakis C

更新日期：1979-08-17 00:00:00

abstract：:The distribution of [3H]kainic acid (KA) binding sites in the rat CNS was determined by in vitro autoradiography. KA sites are distributed throughout the CNS gray matter in an anatomically specific pattern with telencephalic structures and the cerebellum accounting for the majority of the binding. These results, toget...

journal_title：Brain research

authors： Monaghan DT,Cotman CW

更新日期：1982-12-02 00:00:00

abstract：:Diffusion patterns of 14C-labeled penicillin, resulting from microinjections into different neocortical laminae, were compared with simultaneous electrophysiologic monitoring of epileptogenesis across these laminae. Injections into layer IV produced response alterations quickly in all recorded layers even with penicil...

journal_title：Brain research

authors： Chatt AB,Ebersole JS

更新日期：1984-01-09 00:00:00

abstract：:We analyzed flotillin-1 expression in the spinal cords of Lewis rats with experimental autoimmune encephalomyelitis (EAE). Western blot analysis showed that flotillin-1 expression increased significantly in the spinal cords from rats at the peak stage of EAE compared with the levels in control animals (p<0.05) and dec...

journal_title：Brain research

authors： Kim H,Ahn M,Moon C,Matsumoto Y,Sung Koh C,Shin T

更新日期：2006-10-09 00:00:00

abstract：:We utilized nylon arrays to measure gene expression in mouse brains after various postmortem intervals (PMIs). Gene expression after overnight refrigeration or 4 h at room temperature then overnight refrigeration correlated highly and approximately equivalently to that in brains processed immediately. After 8-24 h at ...

journal_title：Brain research

authors： Trotter SA,Brill LB 2nd,Bennett JP Jr

更新日期：2002-06-28 00:00:00

abstract：:The intracellular free Ca2+ concentration ([Ca2+]i) of the bullfrog sympathetic ganglion cell was measured with fura-2 fluorescence under various conditions, and compared with changes in membrane potential recorded with an intracellular electrode. The [Ca2+]i was 109 nM on average under the resting condition and incre...

journal_title：Brain research

authors： Nohmi M,Kuba K,Ogura A,Kudo Y

更新日期：1988-01-12 00:00:00