Comparison of arterial and capillary blood gas values in poisoning department assessment.

Abstract:

:The aim of this study was to compare simultaneously obtained arterial and capillary blood gas (CBG) values in comatose-poisoned patients presented with stable vital signs. Forty-five adult patients with a diagnosis of coma because of poisoning and stable vital signs were included in this prospective study. With respect to pH, the arterial blood gas (ABG) and CBG values correlated satisfactorily (r(2) = .91) and had an acceptable limit of agreements (LOAs; -0.04 to 0.06). With respect to base excess (BE), the ABG and CBG values correlated well (r(2) = .85), but their 95% LOAs seem too wide to allow substitution (-4.4 to 2.7). PCO(2) (r(2) = .61), HCO(3) (r(2) = .71) and PO(2) (r(2) = .53) correlated less reliably. A capillary PCO(2) of 51.7 mm Hg had a sensitivity of 100% and a specificity of 95.12% for detecting hypercarbia (area under the curve, 0.99; 95% Confidence Interval, 0.90-0.99; p < .0001). In conclusion, CBG analysis for pH may be a reliable substitute for ABG analysis in the initial evaluation of patients presenting with coma and stable vital signs to the poisoning emergency department (PED). Subsequent ABG may be required in patients with capillary PCO(2) > 51.7 mm Hg.

journal_name

Hum Exp Toxicol

authors

Eizadi-Mood N,Alfred S,Yaraghi A,Huynh C,Moghadam AS

doi

10.1177/0960327109107001

subject

Has Abstract

pub_date

2009-10-01 00:00:00

pages

665-70

issue

10

eissn

0960-3271

issn

1477-0903

pii

0960327109107001

journal_volume

28

pub_type

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