Changes in sexual behavior of adult male and female rats neonatally treated with vitamin D3.

abstract：:A four-fold increase in the iron content of normal subjects was detected in plasma after 5 hours of iron administration. Iron supplementation had a surprisingly erratic effect on four patients with hepatomegaly secondary to heart insufficiency, since the increase in the iron content in the plasma after iron-dextran ad...

journal_title：Human & experimental toxicology

authors： Galleano M,Lemberg A,Puntarulo S

更新日期：2003-07-01 00:00:00

abstract：:Sodium hypochlorite (NaClO) is used extensively as a disinfectant or bleaching agent. Most studies describe ingestion or inhalation route of this product with rare complication and fatalities. Despite global daily exposures, data about bleach injection is limited. Here we report intentional infusion of 20 mL, sodium h...

journal_title：Human & experimental toxicology

authors： Rahmani SH,Ahmadi S,Vahdati SS,Moghaddam HH

更新日期：2012-06-01 00:00:00

abstract：:In acute respiratory distress syndrome (ARDS), there is extensive overproduction of free radicals to the extent that endogenous anti-oxidants are overwhelmed, permitting oxidative cell damage. The present study examined the benefit of the anti-oxidant compound N-acetylcysteine (NAC) in the management of ARDS by measur...

journal_title：Human & experimental toxicology

authors： Soltan-Sharifi MS,Mojtahedzadeh M,Najafi A,Reza Khajavi M,Reza Rouini M,Moradi M,Mohammadirad A,Abdollahi M

更新日期：2007-09-01 00:00:00

abstract：:Acute and chronic arsenic exposure result in toxicity both in human and animal beings and cause many hepatic and renal manifestations. The present study stated that mushroom lectin prevents arsenic-induced apoptosis. Apoptosis was measured by morphological alterations, cell proliferation index (CPI), phagocytic activi...

journal_title：Human & experimental toxicology

authors： Rana T,Bera AK,Das S,Bhattacharya D,Pan D,Bandyopadhyay S,De S,Das SK

更新日期：2011-04-01 00:00:00

abstract：:Acute exposure to systemic poisons represents an important challenge in clinical toxicology. We aimed to analyze the potential role of cardiac biomarkers, routine laboratory tests, and clinical scores as morbidity and in-hospital mortality predictors in patients intoxicated with various systemic poisons. We conducted ...

journal_title：Human & experimental toxicology

authors： Lionte C,Sorodoc V,Tuchilus C,Cimpoiesu D,Jaba E

更新日期：2017-07-01 00:00:00

abstract：:Stem cell transplantation has indicated great promise for cell therapy in a wide range of diseases, but poor and insufficient viability of cells within damaged tissues has limited its potential therapeutic effects. 17 β-Estradiol (E2) is a steroid hormone that plays an important role in expression of many genes and re...

journal_title：Human & experimental toxicology

authors： Mirzamohammadi S,Mehrabani M,Tekiyehmaroof N,Sharifi AM

更新日期：2016-03-01 00:00:00

abstract：:The use of Lucilia sericata larvae on the healing of wounds in diabetics has been reported. However, the role of the excretion/secretion (ES) products of the larvae in treatment of diabetic wounds remains unknown. This study investigated whether application of the ES products of L. sericata on the wound surface could ...

journal_title：Human & experimental toxicology

authors： Tombulturk FK,Kasap M,Tuncdemir M,Polat E,Sirekbasan S,Kanli A,Kanigur-Sultuybek G

更新日期：2018-05-01 00:00:00

abstract：:1 The urinary recovery of metabolites of aspirin (ASA) was studied in 45 volunteers who took a therapeutic dose (600 mg) of ASA by mouth and in 37 patients who took ASA in overdose. 2 The main metabolite recovered from the volunteers was the glycine conjugate, salicyluric acid (SUA), which accounted for 75.01 +/- 1.19...

journal_title：Human & experimental toxicology

authors： Patel DK,Hesse A,Ogunbona A,Notarianni LJ,Bennett PN

更新日期：1990-05-01 00:00:00

abstract：INTRODUCTION:Accidental toxicity by organophosphate (OP) agents may occur among farmers during spraying season due to improper use and handling. Plasma cholinesterase (ChE) activity measurement is recommended to monitor the extent of exposure to the OP agent. The aim of the current study was to measure plasma ChE activ...

journal_title：Human & experimental toxicology

authors： Pakravan N,Shokrzadeh M,Bari MA,Shadboorestan A

更新日期：2016-03-01 00:00:00

abstract：:Sepsis, often initiated by an infection, is a state of disrupted inflammatory homeostasis. There is increasing evidence that oxidative stress has an important role in the development of sepsis-induced multiorgan failure. Resveratrol (RV) is a polyphenolic compound found in the skin of red fruits, such as mulberries an...

journal_title：Human & experimental toxicology

authors： Aydin S,Bacanli M,Taner G,Şahin T,Başaran AA,Başaran N

更新日期：2013-10-01 00:00:00

abstract：:Puerarin, a potent free radicals scavenger, has been demonstrated to have protective efficacy in oxidative damage induced by nephrotoxins. In the present study, the attenuating effect of puerarin (PU) on lead (Pb)-induced apoptosis and oxidative stress was investigated in cultured primary rat proximal tubular (rPT) ce...

journal_title：Human & experimental toxicology

authors： Liu G,Li Z,Wang J,Wang H,Wang Z,Wang L

更新日期：2014-10-01 00:00:00

abstract：:1. In humans morphine is metabolised to morphine-3-glucuronide (M3G) which possess no opioid activity, and morphine-6-glucuronide (M6G) which is a potent opioid receptor agonist that probably contribute to the desired as well as toxic effects of morphine. 2. In order to investigate the possible effect of ranitidine on...

journal_title：Human & experimental toxicology

authors： Aasmundstad TA,Størset P

更新日期：1998-06-01 00:00:00

abstract：:The second-generation selective 5-HT2 receptor antagonists and reuptake inhibitors (SARIs) class antidepressants are known to have fewer cardiovascular side effects than the older ones. However, several case reports showed that trazodone, one of the second-generation SARIs, induces QT prolongation, cardiac arrhythmia,...

journal_title：Human & experimental toxicology

authors： Lee S,Lee HA,Kim SJ,Kim KS

更新日期：2016-05-01 00:00:00

abstract：:Phagocytes remove and store mercury (Hg) that enters the body. Macrophages and granulocytes respond in opposite ways to Hg: macrophages loose cell viability, and neutrophils become protected from apoptosis. We have investigated the cytology of early intake of Hg by macrophages and neutrophils after a short period (2-4...

journal_title：Human & experimental toxicology

authors： Cunha EM,Oliveira MJ,Ferreira PG,Aguas AP

更新日期：2004-08-01 00:00:00

abstract：:Arsenic trioxide (As2O3) is utilized for treating patients suffering from hematological malignancies particularly acute promyelocytic leukemia. Unfortunately, the extensive application of this chemotherapeutic agent has been limited due to its adverse effects such as cardiotoxicity. Ellagic acid, as a phenolic compoun...

journal_title：Human & experimental toxicology

authors： Hemmati AA,Olapour S,Varzi HN,Khodayar MJ,Dianat M,Mohammadian B,Yaghooti H

更新日期：2018-04-01 00:00:00

abstract：:The National Toxicology Program (NTP) Technical Reports online database was reviewed to find chemicals that were reported to show clear evidence of carcinogenicity in the NTP rodent studies and for which data on human exposure could be found. Six representative compounds were selected. Three volatile compounds: ethyl ...

journal_title：Human & experimental toxicology

authors： Waddell WJ

更新日期：2003-09-01 00:00:00

abstract：:Clinical and experimental studies have shown the adverse effects of excess glucocorticoid on testicular testosterone production. The NADPH co-enzyme has been recognized as an important factor that regulates several steps in steroidogenesis, while glucose oxidation acts as a limiting factor on testicular testosterone p...

journal_title：Human & experimental toxicology

authors： Kavitha TS,Parthasarathy C,Sivakumar R,Badrinarayanan R,Balasubramanian K

更新日期：2006-03-01 00:00:00

abstract：:Sulfur dioxide (SO2) is a common exogenous atmospheric pollutant. Studies have shown that SO2 can cause vasodilation as a gas signaling molecule, but the specific signaling pathways are not well understood. This study aimed to explore the underlying mechanism behind the effects of SO2 on vasodilation of isolated rat a...

journal_title：Human & experimental toxicology

authors： Zhang Q,Lyu W,Yu M,Niu Y

更新日期：2020-08-01 00:00:00

abstract：:There is compelling evidence in support of positive associations between zinc (Zn) deficiency and high accumulation of cadmium (Cd) in biological samples of different cancerous patients. The incidence of mouth cancer has been increased among people who possess habit of drinking alcohol, tobacco smoking and chewing wit...

journal_title：Human & experimental toxicology

authors： Kazi TG,Wadhwa SK,Afridi HI,Kazi N,Kandhro GA,Baig JA,Shah AQ,Kolachi NF,Khan S

更新日期：2010-03-01 00:00:00

abstract：:A retrospective review of medical records was carried out to determine the pattern of drug and chemical poisoning cases admitted to a teaching hospital in Malaysia. Medical records of patients admitted during the period January 1987 to December 1995 were reviewed. They accounted for 0.2% of total admissions during the...

journal_title：Human & experimental toxicology

authors： Ab Rahman AF

更新日期：2002-07-01 00:00:00

abstract：:The conventional method for the assessment of acute inhalation toxicity (OECD Test Guideline 403, 1981) uses death of animals as an endpoint to identify the median lethal concentration (LC50). A new OECD Testing Guideline called the Fixed Concentration Procedure (FCP) is being prepared to provide an alternative to Tes...

journal_title：Human & experimental toxicology

authors： Stallard N,Whitehead A,Indans I

更新日期：2003-11-01 00:00:00

abstract：:Celecoxib has been shown to have antitumor effect in previous studies but the mechanisms are unclear. The effect of celecoxib on cytosolic Ca(2+) concentrations ([Ca(2+)]i) and viability in HA59T human hepatoma cells was explored. The Ca(2+)-sensitive fluorescent dye fura-2 was applied to measure [Ca(2+)]i. Celecoxib ...

journal_title：Human & experimental toxicology

authors： Cheng HH,Chou CT,Lu YC,Lu T,Chi CC,Tseng LL,Liu SI,Cheng JS,Kuo CC,Liang WZ,Jan CR

更新日期：2014-11-01 00:00:00

abstract：:The common effects of acetaminophen (paracetamol), isopropylantipyrine (propyphenazone) and caffeine on fetal development were examined in rats. The mixture was given in Tween 80 solution once daily, in a constant proportion of 5:3:1, during days 8-14 of gestation in three different doses. Dose S1 - 3.5 mg/kg acetamin...

journal_title：Human & experimental toxicology

authors： Burdan F

更新日期：2002-01-01 00:00:00

abstract：UNLABELLED:A single dose of monocrotaline, a pyrrolizidine alkaloid, was injected into rats in order to produce 25 (Group I) and 45 (Group II) days later a progressive and so called delayed liver injury. The present study investigated the prostanoid production of Kupffer cells and endothelial cells separated from Monoc...

journal_title：Human & experimental toxicology

authors： Lemberg A,Calabrese G,Majowicz M,Peredo H,Scorticati C,Filinger E,Perazzo JC

更新日期：1998-10-01 00:00:00

abstract：INTRODUCTION:Poisoning from organophosphates and carbamates is a significant cause of morbidity and mortality worldwide. Concerns have been expressed over the safety and efficacy of the use of oximes such as pralidoxime (2-PAM) in patients with carbamate poisoning in general, and more so with carbaryl poisoning specifi...

journal_title：Human & experimental toxicology

authors： Mercurio-Zappala M,Hack JB,Salvador A,Hoffman RS

更新日期：2007-02-01 00:00:00

abstract：:The regulation of osteoblast proliferation is a key factor in maintaining bone mass. The enhancement of this process can be achieved by stimulating the proliferation of these cells. Mechanical stimulation is one of the important enhancing factors, but the exact cellular mechanisms of mechanical stimulation, i.e., mech...

journal_title：Human & experimental toxicology

authors： Rosenberg N

更新日期：2003-05-01 00:00:00

abstract：:The aim of the present study was to investigate whether cognitive behavioral impairment, induced by nicotine in offspring rats, was associated with the alteration of hippocampal short-term potentiation (STP) and long-term potentiation (LTP) and to discuss the potential underlying mechanism. Young adult offspring rats ...

journal_title：Human & experimental toxicology

authors： Han G,An L,Yang B,Si L,Zhang T

更新日期：2014-02-01 00:00:00

abstract：:The aim of this study was to compare the number of inactivated-influenza vaccine-related spontaneous abortion and stillbirth (SB) reports in the Vaccine Adverse Event Reporting System (VAERS) database during three consecutive flu seasons beginning 2008/2009 and assess the relative fetal death reports associated with t...

journal_title：Human & experimental toxicology

authors： Goldman GS

更新日期：2013-05-01 00:00:00

abstract：:Occupational chronic solvent encephalopathy (CSE) is associated with a number of neurobehavioural disorders including defects of visual perception. The purpose of this study was to characterize colour vision defects in CSE patients. Colour vision was tested in bright illumination with the Farnsworth-Munsell 100-hue te...

journal_title：Human & experimental toxicology

authors： Päällysaho J,Näsänen R,Mäntyjärvi M,Kaukiainen A,Sainio M

更新日期：2007-04-01 00:00:00

abstract：:Diallyl sulfide, a sulfur-containing volatile compound present in garlic (Allium sativum), exerts anticarcinogenic activity in various rodent tumor models. In the present study, apoptosis-inhibiting effects of diallyl sulfide against a carcinogenic polycyclic aromatic hydrocarbon, 7,12-dimethyl benz(a)anthracene (DMBA...

journal_title：Human & experimental toxicology

authors： Prasad S,Kalra N,Srivastava S,Shukla Y

更新日期：2008-01-01 00:00:00