Peritoneal injection of fucoidan suppresses the increase of plasma IgE induced by OVA-sensitization.

abstract：:We have examined the response of the human multidrug resistance gene-1 (MDR1) downstream promoter to various mutants of human p53 in a reporter assay system. Our findings indicate that mutant 175H inhibits reporter activity driven by the MDR1 downstream promoter (base pairs -189 to +133 relative to the major transcrip...

journal_title：Biochemical and biophysical research communications

authors： Strauss BE,Haas M

更新日期：1995-12-05 00:00:00

abstract：:Long-chained 1-mercapto-n-alkanes showed potent inhibitory effects on horse liver alcohol dehydrogenase (HLADH). The inhibitory effect of the thiols was enhanced by increasing the number of the alkyl carbon atoms up to 10-12 and steeply lowered by further increase in the carbon number. The HLADH activity was almost co...

journal_title：Biochemical and biophysical research communications

authors： Miwa K,Okuda H,Ogura K,Watabe T

更新日期：1987-02-13 00:00:00

abstract：:The effect of ochratoxin A on the specific activities of phosphoenolpyruvate carboxykinase, gamma-glutamyl transpeptidase and phosphate-dependent glutaminase were investigated in primary cultures of rat kidney proximal convoluted tubule cells grown in a serum-free medium supplemented with growth factors. Addition of o...

journal_title：Biochemical and biophysical research communications

authors： Thekkumkara TJ,Patel MS

更新日期：1989-08-15 00:00:00

abstract：:SMG-9 is a component of the NMD complex, a heterotetramer that also includes SMG-1 and SMG-8 in the complex. SMG-9 was also originally identified as a tyrosine-phosphorylated protein but the role of the phosphorylation is not yet known. In this study, we determined that IQGAP protein, an actin cytoskeleton modifier ac...

journal_title：Biochemical and biophysical research communications

authors： Takeda S,Fujimoto A,Yamauchi E,Hiyoshi M,Kido H,Watanabe T,Kaibuchi K,Ohta T,Konishi H

更新日期：2011-06-24 00:00:00

abstract：:Cellular uptake of succinylated catalase (Suc-CAT; Mw 227 kDa), bovine serum albumin (Suc-BSA; Mw 70 kDa), superoxide dismutase (Suc-SOD; Mw 34 kDa) and soybean trypsin inhibitor (Suc-STI; Mw 21 kDa) was studied using primary cultures of bovine brain microvessel endothelial cells (BMECs) developed as an in vitro model...

journal_title：Biochemical and biophysical research communications

authors： Tokuda H,Masuda S,Takakura Y,Sezaki H,Hashida M

更新日期：1993-10-15 00:00:00

abstract：:ATP-binding cassette sub-family G member 2 (ABCG2) confers to the major phenotypes of side population (SP) cells, the cancer stem-like cells. In this study, the SP cells displayed a distinctly higher ABCG2 expression level, sphere formation efficiency (SFE) and growth rate even under hypoxia condition. CXCR4 overexpre...

journal_title：Biochemical and biophysical research communications

authors： He C,Zhang H,Wang B,He J,Ge G

更新日期：2018-10-28 00:00:00

abstract：:BRCT(BRCA1) plays a major role in DNA repair pathway, and does so by recognizing the conserved sequence pSXXF in its target proteins. Remarkably, tetrapeptides containing pSXXF motif bind with high specificity and micromolar affinity. Here, we have characterized the binding interactions of pSXXF tetrapeptides using NM...

journal_title：Biochemical and biophysical research communications

authors： Joseph PR,Yuan Z,Kumar EA,Lokesh GL,Kizhake S,Rajarathnam K,Natarajan A

更新日期：2010-03-05 00:00:00

abstract：:The detergent (Triton X-100, 4°C)-resistant membrane (DRM)-associated membrane proteins stomatin, sorcin, and synexin (anexin VII) exposed on the cytoplasmic side of membrane were investigated for their lateral distribution in relation to induced ganglioside(M1) (GM1) raft patches in flat (discocytic) and curved (echi...

journal_title：Biochemical and biophysical research communications

authors： Mrówczyńska L,Salzer U,Perutková S,Iglič A,Hägerstrand H

更新日期：2010-10-22 00:00:00

abstract：:Secreted gelatinase from human neutrophils was purified as a 94 kDa polypeptide. Gelatinolytic and type IV collagenolytic activities of the purified protein were measured and compared. Immunoglobulins purified from antisera raised against gelatinase inhibited both the gelatinase and type IV collagenase activities. The...

journal_title：Biochemical and biophysical research communications

authors： Morel F,Berthier S,Guillot M,Zaoui P,Massoubre C,Didier F,Vignais PV

更新日期：1993-02-26 00:00:00

abstract：:Myocardial cells respond to changes in the mechanical forces imposed on them with changes in myocardial tension in the short term and with structural remodeling in the long term. Since these responses involve intercellular communication, we have investigated regulation of the gap junction proteins, connexin 43 (Cx43),...

journal_title：Biochemical and biophysical research communications

authors： Wang TL,Tseng YZ,Chang H

更新日期：2000-01-19 00:00:00

abstract：:Loss of CRY2 confers aggressive phenotypes to breast cancer. However, the mechanism of its downregulation and its prognostic value in breast cancer are still not clear. Our data mining in TCGA breast cancer cohort (TCGA-BRCA) showed that the luminal A subtype of breast cancer had the highest CRY2 expression, while the...

journal_title：Biochemical and biophysical research communications

authors： Liu L,Shen H,Wang Y

更新日期：2017-08-12 00:00:00

abstract：:In this work, we examined the functions of the female hormone "estrogen" on spermatogenesis of the Japanese eel (Anguilla japonica). Estradiol-17beta (E(2)), a natural estrogen in vertebrates, was present in the serum and its receptor was expressed in the testis during the whole process of spermatogenesis. Spermatogon...

journal_title：Biochemical and biophysical research communications

authors： Miura T,Miura C,Ohta T,Nader MR,Todo T,Yamauchi K

更新日期：1999-10-14 00:00:00

abstract：:A fragment of human gene for pregnancy-specific beta 1-glycoprotein(s), recently identified CEA family member(s), has been cloned. Analyses of nucleotide and deduced amino acid sequences revealed that it carried, from 5' to 3' direction, exons IA, IB, IIA, IIB, C3, C1 and C2, the first four encoding peptides distinct ...

journal_title：Biochemical and biophysical research communications

authors： Oikawa S,Inuzuka C,Kosaki G,Nakazato H

更新日期：1988-10-14 00:00:00

abstract：:We identified a DNA polymerase species in Drosophila melanogaster embryos, and purified it. This polymerase shared some common properties with DNA polymerase epsilon from mammals and yeast as follows; it has a preference for poly(dA)/oligo(dT) as a template/primer, it is highly processive in DNA synthesis, it co-fract...

journal_title：Biochemical and biophysical research communications

authors： Aoyagi N,Oshige M,Hirose F,Kuroda K,Matsukage A,Sakaguchi K

更新日期：1997-01-13 00:00:00

abstract：:Oscillatory gene expression plays an important role in somite segmentation during the early developmental stages of vertebrates. Recent experimental studies have shown that microRNA can regulate gene expression by stimulating degradation of mRNA and/or repression of translation. In this communication, we incorporate m...

journal_title：Biochemical and biophysical research communications

authors： Xie ZR,Yang HT,Liu WC,Hwang MJ

更新日期：2007-07-06 00:00:00

abstract：:Two ornithine transcarbamylase-deficient mice are available, the spf with a variant enzyme and spf-ash with a markedly decreased enzyme protein. Genomic DNA, mRNA and the nuclear precursors for the enzyme in these mutants were analyzed. Southern blot analysis of genomic DNA showed no abnormality in the mutant mice. Bl...

journal_title：Biochemical and biophysical research communications

authors： Ohtake A,Takayanagi M,Yamamoto S,Nakajima H,Mori M

更新日期：1987-08-14 00:00:00

abstract：:Phosphorylation of a 25 Kdalton nuclear stress protein from rat muscle was examined by two-dimensional gel electrophoresis and one-dimensional peptide mapping. These studies show that three 25 Kdalton stress proteins found in stressed rat myoblasts are actually the same protein with charge variation brought about by m...

journal_title：Biochemical and biophysical research communications

authors： Kim YJ,Shuman J,Sette M,Przybyla A

更新日期：1983-12-28 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine whether ATP-binding cassette transporter A1 (ABCA1) was up-regulated by growth differentiation factor-15 (GDF-15) via the phosphoinositide 3-kinase (PI3K)/protein kinase Cζ (PKCζ)/specificity protein 1 (SP1) pathway in THP-1 macrophages. METHODS AND RESULTS:We investiga...

journal_title：Biochemical and biophysical research communications

authors： Wu JF,Wang Y,Zhang M,Tang YY,Wang B,He PP,Lv YC,Ouyang XP,Yao F,Tan YL,Tang SL,Tang DP,Cayabyab FS,Zheng XL,Zhang DW,Zeng GF,Tang CK

更新日期：2014-02-14 00:00:00

abstract：:Wnt/beta-catenin signaling plays an important role not only in cancer, but also in cancer stem cells. In this study, we found that beta-catenin and OCT-4 was highly expressed in cisplatin (DDP) selected A549 cells. Stimulating A549 cells with lithium chloride (LiCl) resulted in accumulation of beta-catenin and up-regu...

journal_title：Biochemical and biophysical research communications

authors： Teng Y,Wang X,Wang Y,Ma D

更新日期：2010-02-12 00:00:00

abstract：:Atherosclerosis-related vascular complications in beta-thalassemia/hemoglobin E (beta-thal/Hb E) patients may result from iron induced oxidation of lipoproteins. To identify the specific site of oxidative damage, changes in lipid fluidity at different regions in LDL and HDL particle were investigated using two fluores...

journal_title：Biochemical and biophysical research communications

authors： Morales NP,Charlermchoung C,Luechapudiporn R,Yamanont P,Fucharoen S,Chantharaksri U

更新日期：2006-11-24 00:00:00

abstract：:We studied the effects of interleukin-6(IL-6) on DNA synthesis and cyclic AMP production in rat thyroid FRTL-5 cells. When cells were incubated with IL-6 in the presence or absence of IGF-I, cell proliferation was not observed. By contrast, IL-6 stimulated DNA synthesis in a dose dependent manner when TSH was added co...

journal_title：Biochemical and biophysical research communications

authors： Nishiyama S,Takada K,Tada H,Takano T,Amino N

更新日期：1993-04-15 00:00:00

abstract：:The distribution, labeling and interrelationship of microsomal and lysosomal dolichol and dolichyl-P in rat liver was investigated. After membrane induction with phenobarbital, N-nitrosodiethylamine and diethylhexylphthalate, the amount of microsomal and lysosomal dolichols are modulated independently. Liposomal label...

journal_title：Biochemical and biophysical research communications

authors： Edlund C,Chojnacki T,Dallner G

更新日期：1983-09-30 00:00:00

abstract：:Tyrosine protein kinase activity was measured in membranes from DMBA-induced mammary tumors, with Angiotensin II as substrate. The apparent Km for the peptide was 3.3 mM. This enzymatic activity is inhibited by Ca+2; Mn+2 can replace Mg+2 with an increase in the Km for ATP from 47 /microM to 172 microM. The enzymatic ...

journal_title：Biochemical and biophysical research communications

authors： Levy J,Teuerstein I,Marbach M,Radian S,Sharoni Y

更新日期：1984-09-28 00:00:00

abstract：:Estrogen receptor alpha (ERα) is a nuclear receptor that regulates a range of physiological processes in response to estrogens. In order to study its biological role, we generated a floxed ERα mouse line that can be used to knock out ERα in selected tissues by using the Cre/LoxP system. In this study, we established a...

journal_title：Biochemical and biophysical research communications

authors： Antonson P,Omoto Y,Humire P,Gustafsson JÅ

更新日期：2012-08-10 00:00:00

abstract：:The purpose of the present study is to characterize the ENaC-mediated Na+ absorption in human upper airway epithelia, nasal cavity, and paranasal sinus. To perform the purpose, we obtained epithelial cells from human nasal polyp (NP) and paranasal sinus mucosa (PSM) by endoscopic surgery. We measured the short-circuit...

journal_title：Biochemical and biophysical research communications

authors： Yasuda M,Niisato N,Miyazaki H,Iwasaki Y,Hama T,Dejima K,Hisa Y,Marunaka Y

更新日期：2007-10-26 00:00:00

abstract：:Specifier proteins are important components of the glucosinolate-myrosinase system, which mediate plant defense against herbivory and pathogen attacks. Upon tissue disruption, glucosinolates are hydrolyzed to instable aglucones by myrosinases, and then aglucones will rearrange to form defensive isothiocyanates. Specif...

journal_title：Biochemical and biophysical research communications

authors： Zhang W,Wang W,Liu Z,Xie Y,Wang H,Mu Y,Huang Y,Feng Y

更新日期：2016-09-16 00:00:00

abstract：:To explore the mechanism of glucocorticoid-induced osteoporosis, we investigated the effect of glucocorticoid on canonical Wnt signaling that emerged as a novel key pathway for promoting bone formation. Wnt3a increased the T-cell factor (Tcf)/lymphoid enhancer factor (Lef)-dependent transcriptional activity in primary...

journal_title：Biochemical and biophysical research communications

authors： Ohnaka K,Tanabe M,Kawate H,Nawata H,Takayanagi R

更新日期：2005-04-01 00:00:00

abstract：:In order to study the role of phosphatidylinositol-3-kinase (PI3K) in insulin action, we employed a specific inhibitor of PI3K, LY294002, and measured five biological functions of insulin in mouse 3T3 fibroblasts overexpressing human insulin receptors. LY294002 had no effect on tyrosine phosphorylation of both the ins...

journal_title：Biochemical and biophysical research communications

authors： Sanchez-Margálet V,Goldfine ID,Vlahos CJ,Sung CK

更新日期：1994-10-28 00:00:00

abstract：:Glucocorticoid-suppressible hyperaldosteronism (GSH) is one variety of primary aldosteronism with hypertension and is inherited in an autosomal dominant mode. A recent report has indicated that GSH is caused by a gene duplication arising from unequal crossing over between the two genes, CYP11B1 and CYP11B2, encoding P...

journal_title：Biochemical and biophysical research communications

authors： Miyahara K,Kawamoto T,Mitsuuchi Y,Toda K,Imura H,Gordon RD,Shizuta Y

更新日期：1992-12-15 00:00:00

abstract：:The effects of fibroblast growth factor (FGF) on testicular aromatase activity has been studied using primary cultures of porcine Leydig cells. After culture for 3 days in the absence or presence of FGF, the ability of the cells to produce estrogen was examined in a 4h-test period in which either (a) hCG (10(-9) M) or...

journal_title：Biochemical and biophysical research communications

authors： Raeside JI,Berthelon MC,Sanchez P,Saez JM

更新日期：1988-02-29 00:00:00