Stability of analytes related to clinical chemistry and bone metabolism in blood specimens after delayed processing.

Abstract:

OBJECTIVES:We investigated the stability of 36 analytes related to clinical chemistry in a controlled storage study. DESIGN AND METHODS:Blood was collected from 11 subjects and was maintained for 45 min, 2.5 h, 5 h, or 24 h after phlebotomy before centrifugation. RESULTS:Statistically significant changes were observed only for parathyroid hormone, osteocalcin, zinc, pyridoxal 5'-phosphate, and homocysteine. CONCLUSIONS:These studies indicate that many analytes in clinical chemistry are stable for 24 h before centrifugation.

journal_name

Clin Biochem

journal_title

Clinical biochemistry

authors

Zwart SR,Wolf M,Rogers A,Rodgers S,Gillman PL,Hitchcox K,Ericson KL,Smith SM

doi

10.1016/j.clinbiochem.2009.02.010

subject

Has Abstract

pub_date

2009-06-01 00:00:00

pages

907-10

issue

9

eissn

0009-9120

issn

1873-2933

pii

S0009-9120(09)00095-2

journal_volume

42

pub_type

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