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Clinical validation of a new blood collection tube for the accuracy of total homocysteine measurement by different methods.

Abstract：

OBJECTIVE:To evaluate the clinical use of Homocysteine-Primavette, a new blood collection medium for total homocysteine (tHcy) assay. METHODS:The agreement between baseline tHcy and tHcy in stabilized samples (40 h) was assessed for FPIA, HPLC, GC-MS, LC-MS, and ICL. RESULTS:tHcy concentrations in whole blood were stable for 40 h in Hcy-Primavette tubes. CONCLUSION:Primavette tubes are a good alternative for the accurate tHcy measurement and no readjustment of reference intervals is needed.

journal_name

Clin Biochem

journal_title

Clinical biochemistry

authors

Bissé E,Epting T,Kögel G,Obeid R,Gempel K,Huzly D,Fuhrmann K,Rolinski B,Herrmann W,Wieland H

doi

10.1016/j.clinbiochem.2007.03.005

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

739-43

issue

9-10

eissn

0009-9120

issn

1873-2933

pii

S0009-9120(07)00128-2

journal_volume

40

pub_type

杂志文章

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