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A liquid chromatographic method for the determination of AY-25,712, a lipid-lowering agent, in serum.

Abstract：

:We report a sensitive and specific method for the determination of AY-25,712 concentrations in rat, dog and human serum by liquid chromatography with UV detection. The detection limit is 25 ng/mL, based on 2 mL of serum or plasma. The method has been validated in human volunteers receiving single oral doses of AY-25,712 (25 to 900 mg).

journal_name

Clin Biochem

journal_title

Clinical biochemistry

authors

Gonzalez R,Thibeault D

doi

10.1016/s0009-9120(83)90112-1

subject

Has Abstract

pub_date

1983-08-01 00:00:00

pages

244-8

issue

4

eissn

0009-9120

issn

1873-2933

pii

S0009-9120(83)90112-1

journal_volume

16

pub_type

杂志文章

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