Undetectable AMH at 3 days of age: a clue to bilateral anorchia.

abstract：:1. An automated method is described for the assay of pregnancy serum cystine aminopeptidase (Oxytocinase, E.C. 3.4.1.10) using continuous flow analysis. S-Genzyl-L-cysteine-p-nitroanilide, the most highly specific substrate so far available for oxytocinase is employed in this assay. Comparison with the manual method f...

journal_title：Clinical biochemistry

authors： Small CW,Watkins WB

更新日期：1975-04-01 00:00:00

abstract：OBJECTIVE:Develop a simple LC-MS-MS method for determination of 25-hydroxymetabolites of vitamin D2 and D3 in serum. DESIGN AND METHODS:0.1 mL serum was mixed with 0.3 mL deproteinizing mixture containing two deuterated internal standards. Two LC-MS-MS systems were used: Waters Premier with an ESI source and a Hypersi...

journal_title：Clinical biochemistry

authors： Bogusz MJ,Al Enazi E,Tahtamoni M,Jawaad JA,Al Tufail M

更新日期：2011-11-01 00:00:00

abstract：:We present data comparing the Roche CEA radioimmunoassay (RIA) utilizing ultrafiltration and the Abbott CEA immunoradiometric assay (IRMA) methods for standard curve sensitivity, analytical reproducibility, recovery (pre and post extraction), dilution linearity, and patient correlation. The Roche intra- and inter-assa...

journal_title：Clinical biochemistry

authors： Valdes R Jr,Stein KE

更新日期：1982-10-01 00:00:00

abstract：:We report a case of metastatic adenocarcinoma of the prostate with widespread bony and hepatic involvement having extremely high BB isoenzyme of creatine kinase in serum (2405 U/liter). The serum LD5/LD1 ratio is greater than one, with total LD activity more than twenty-five fold the normal value. The homogenate of pr...

journal_title：Clinical biochemistry

authors： Sandhu RS,Conover RE

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVES:To develop a tandem mass spectrometry (MS/MS) method for plasma free and total carnitine, incorporating acid hydrolysis for total carnitine measurement, for improved accuracy and sample throughput. DESIGN AND METHODS:Limit of detection (LOD), limit of quantitation (LOQ), linearity, accuracy, precision coeff...

journal_title：Clinical biochemistry

authors： Johnson DW

更新日期：2010-11-01 00:00:00

abstract：OBJECTIVES:To determine salivary cortisol reference intervals in a healthy adult population, at 6 different time points during a 24-hour (h) period. METHODS:In a prospective study, salivary cortisol concentrations were measured upon waking, one-hour post-waking and at specific times of the day: at 12 h00, 16 h00, 20 h...

journal_title：Clinical biochemistry

authors： Gagnon N,Fréchette I,Mallet PL,Dubé J,Houde G,Fink GD

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:To evaluate platelet activating factor (PAF) levels, its metabolic enzymes activity and its associations with other inflammatory markers in heart failure (HF) patients. DESIGN AND METHODS:PAF, and two of its key biosynthetic enzymes [lyso-PAF acetyltransferase (lyso-PAF-AT) and DTT-insensitive CDP-choline:1...

journal_title：Clinical biochemistry

authors： Detopoulou P,Nomikos T,Fragopoulou E,Antonopoulou S,Kotroyiannis I,Vassiliadou C,Panagiotakos DB,Chrysohoou C,Pitsavos C,Stefanadis C

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The immune-inflammatory system has been implicated in the pathogenesis of diabetic nephropathy; however, many of the mechanisms involved remain unclear. Chitotriosidase enzyme is an active human chitinase and a major protein product of activated macrophages. Although playing an important role in innate and ac...

journal_title：Clinical biochemistry

authors： Elmonem MA,Amin HS,El-Essawy RA,Mehaney DA,Nabil M,Kamel LN,Farid IM

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVES:Behçet's disease is a multisystem disorder characterized by a chronic inflammation including acute attacks and remission periods. Decreased enzyme activity of the antioxidant system and increased levels of free radicals may have important roles in the damage of tissues observed in the disease period. In addi...

journal_title：Clinical biochemistry

authors： Orem A,Yandi YE,Vanizor B,Cimşit G,Uydu HA,Malkoç M

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:This study explored the relationship between oxidative stress biomarkers and stability of carotid plaque. We decided to analyze the broad range of parameters describing oxidative stress in patients with carotid stenosis. DESIGN AND METHODS:124 consecutive patients undergoing carotid endarterectomy were enro...

journal_title：Clinical biochemistry

authors： Rozalski R,Migdalski A,Gackowski D,Guz J,Siomek A,Foksinski M,Szpila A,Zarakowska E,Majer M,Jawien A,Olinski R

更新日期：2013-08-01 00:00:00

abstract：:The synthesis and characterisation of a new colorimetric reagent for iron, 3-(2-pyridyl)-5,6-bis(2-furyl)-1,2,4-triazine are described. Peak assignments and chemical shifts of the high resolution 13C nmr spectrum are given. The reagent forms a tris iron(II) complex with epsilon max of 32000 Lcm-1 mol-1 at 577 nm. The ...

journal_title：Clinical biochemistry

authors： Smith FE,Herbert J,Gaudin J,Hennessy DJ,Reid GR

更新日期：1984-10-01 00:00:00

abstract：OBJECTIVE:We aimed to establish correlations for the levels of follicle-stimulating hormone (FSH), estrone (E1) and estradiol (E2) between urine and serum in premenopausal and postmenopausal women using immunoassays. METHODS:In this study of 92 women (61 postmenopausal, 31 premenopausal), both urine and blood specimen...

journal_title：Clinical biochemistry

authors： Onizuka Y,Nagai K,Ideno Y,Kitahara Y,Iwase A,Yasui T,Nakajima-Shimada J,Hayashi K

更新日期：2019-11-01 00:00:00

abstract：:Improving long-term management, life-quality and outcome of transplant recipients continues to be a challenge. The impact of highly chemoattractant proteins as chemokines on transplant outcome is undeniable. These immunoactive molecules are critical in a wide variety of physiological and pathological processes, such a...

journal_title：Clinical biochemistry

authors： Crescioli C

更新日期：2016-03-01 00:00:00

abstract：:An ion-exchange chromatographic procedure is described which facilitates the determination of beta-chain aminoterminal modified glycated hemoglobin. The procedure includes an erythrocyte lysis reagent which eliminates the labile aldimine component (pre-A1c) and a two-stage elution step which separates HbA, 1a + b from...

journal_title：Clinical biochemistry

authors： Jaynes PK,Willis MC,Chou PP

更新日期：1985-02-01 00:00:00

abstract：:A simple method for the determination of triodothyronine (T3) uptake using I125-T3 and dextran coated charcoal is described. This reaction is time dependent after the addition of dextran coated charcoal. Effect of temperature, concentrations of I125-T3 and charcoal are reported. Within-run precision has been estimated...

journal_title：Clinical biochemistry

authors： Locong AH

更新日期：1976-02-01 00:00:00

abstract：:Point of Care Testing (POCT) refers to clinical laboratory testing performed outside the central laboratory, nearer to the patient and sometimes at the patient bedside. The testing is usually performed by clinical staff, such as physicians or nurses, who are not laboratory trained. This document was developed by the P...

journal_title：Clinical biochemistry

authors： Venner AA,Beach LA,Shea JL,Knauer MJ,Huang Y,Fung AWS,Dalton J,Provencal M,Shaw JLV

更新日期：2021-02-01 00:00:00

abstract：:The discovery of the causal association of adenosine deaminase (ADA) and purine nucleoside phosphorylase (PNP) deficiency with some forms of primary immunodeficiency disease had led to new approaches to therapy, such as enzyme replacement. In ADA deficiency, bone marrow transplantation remains the primary method of ch...

journal_title：Clinical biochemistry

authors： Zegers BJ,Stoop JW

更新日期：1983-02-01 00:00:00

abstract：OBJECTIVE:To develop a tool to assess the clinical accuracy of glucose meter performance using an insulin dosing protocol to assess the frequency and extent of error in insulin dose categories. METHODS:Retrospective comparison of 1815 glucose meter and central laboratory glucose results obtained from 1698 critically i...

journal_title：Clinical biochemistry

authors： Lyon ME,Lyon OAS,Tran NK,DuBois JA,Lyon AW

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:With the advent of the new high-sensitivity troponin assays, it is becoming critical to measure troponin accurately to low concentrations. To ensure assay performance is acceptable, appropriate QC must be run. METHODS:In addition to the routine use of commercial QC material, we prepared pools of human QC ma...

journal_title：Clinical biochemistry

authors： Hickman PE,Koerbin G,Badrick T,Oakman C,Potter JM

更新日期：2018-08-01 00:00:00

abstract：OBJECTIVE:To quantitatively summarize the association between tumour necrosis factor alpha (TNF-alpha) gene polymorphisms and Graves' disease. DESIGN AND METHODS:Relevant studies were identified from the following electronic databases: Cochrane Library, MEDLINE, EMBASE and Chinese Bio-medicine Database. A meta-analysi...

journal_title：Clinical biochemistry

authors： Li N,Zhou Z,Liu X,Liu Y,Zhang J,Du L,Wei M,Chen X

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:To evaluate impact of risk estimation parameters for screening for Down Syndrome during the first and second trimesters. METHODS:We prospectively examined for their performance in the prenatal prediction of trisomy 21, alphafetoprotein (AFP), unconjugated estriol (uE3), total human chorionic gonadotropin (h...

journal_title：Clinical biochemistry

authors： Forest JC,Massé J,Rousseau F,Moutquin JM,Brideau NA,Bélanger M

更新日期：1995-08-01 00:00:00

abstract：OBJECTIVE:To evaluate a novel surface plasmon resonance (SPR) system for the direct measurement of tumor marker carbohydrate antigen 15-3 (CA15-3) in human saliva. DESIGN AND METHODS:We measured the presence of the tumor marker carbohydrate antigen 15-3 (CA15-3) in human saliva using 2 different surface plasmon resona...

journal_title：Clinical biochemistry

authors： Liang YH,Chang CC,Chen CC,Chu-Su Y,Lin CW

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVES:Renal dysfunction has been reported in normoalbuminuric patients, demonstrating the necessity to improve the diagnostic and prognostic tools for diabetic kidney disease (DKD) investigation. Therefore, the aim of this study was to investigate whether the urinary levels of neutrophil gelatinase-associated lipo...

journal_title：Clinical biochemistry

authors： de Carvalho JA,Tatsch E,Hausen BS,Bollick YS,Moretto MB,Duarte T,Duarte MM,Londero SW,Premaor MO,Comim FV,Delanghe JR,Moresco RN

更新日期：2016-02-01 00:00:00

abstract：OBJECTIVES:Studies from both experimental animals and humans suggest that administration of exogenous DHEA may have beneficial endocrine-metabolic, immunologic and neurologic effects. Several groups have administered DHEA to humans, but to the best of our knowledge, no one at this point has published a summary of the r...

journal_title：Clinical biochemistry

authors： Tummala S,Svec F

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Measurement of 25(OH)D has evolved rapidly, with an increased number of high-throughput automated immunoassays becoming available in recent years. The aim of this study was to fully evaluate six commercially available automated 25(OH)D immunoassays, including 2 newly available (Beckman Coulter) and one recal...

journal_title：Clinical biochemistry

authors： Wyness SP,Straseski JA

更新日期：2015-11-01 00:00:00

abstract：:The initial step in the action of thyrotropin (TSH) is its binding to the TSH receptor. TSH receptor antibodies are detected in up to 90% of patients with Graves' disease. Serial measurements of TSH receptor antibodies in patients with Graves' hyperthyroidism are helpful in predicting relapse. The TSH receptor was pur...

journal_title：Clinical biochemistry

authors： Harrison LC,Leedman PJ

更新日期：1990-02-01 00:00:00

abstract：:In order to evaluate cardiovascular risk, we analyzed the lipid composition of HDL and the presence of lipoprotein(a) [Lp(a)] by both agarose gel electrophoresis and enzyme-linked immunoassay (ELISA). In 681 plasmas we found a close correspondence between the existence of a visible sinking pre-beta lipoprotein band an...

journal_title：Clinical biochemistry

authors： Alvarez JJ,Lasunción MA,Olmos JM,Herrera E

更新日期：1993-10-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to test the susceptibility of THP-1 macrophages to develop oxidative stress and to deploy antioxidant defense mechanisms that insure the balance between the pro- and antioxidant molecules. DESIGN AND METHODS:Differentiated THP-1 were incubated in the presence or absence of iron-as...

journal_title：Clinical biochemistry

authors： Marcil V,Lavoie JC,Emonnot L,Seidman E,Levy E

更新日期：2011-07-01 00:00:00

abstract：:A method is described for xylose determination on the Ciba-Corning 550 Express that utilizes the slower enzymatic action of glucose dehydrogenase (GDH) on D-xylose, after prior removal of glucose. Glucose oxidase is added to serum or urine and incubated for 120 min at 37 degrees C. After incubation, a perchloric acid ...

journal_title：Clinical biochemistry

authors： Mori L

更新日期：1994-02-01 00:00:00

abstract：:1. The following proteolytic enzymes were measured in muscles of control subjects and patients with muscular dystrophies and related neuromuscular diseases: an elastase-like enzyme, carboxypeptidase A, carboxypeptidase B and pyroglutamyl peptidase. 2. Elastase-like enzyme and carboxypeptidase B did not show significan...

journal_title：Clinical biochemistry

authors： Kar NC,Pearson CM

更新日期：1979-04-01 00:00:00