Abstract:
OBJECTIVES:Study of outcomes of pregnancy in women with congenital heart disease. MATERIAL AND METHODS:The cardiac state during and after pregnancy was analysed in 173 women (mean age 28 years, range 21-41) referred for fetal echocardiography and evaluation of maternal heart during 201 pregnancies. Acyanotic lesions were present in 152 women (100 operated), in 175 pregnancies; cyanotic lesions in 21, all operated, in 26 pregnancies. Eighteen patients in 20 pregnancies (9.9% pregnancies) presented an increased risk due to severe arrhythmias or relevant residual hemodynamic lesions (risk group). RESULTS:Complications related to heart defects occurred in 9/201 (4.5%), pregnancies: in 6/175 (3.4%) pregnancies with acyanotic lesions, in 3/26 (11.5%) with cyanotic lesions and in 9/20 pregnancies of the risk group (45%), with a statistically significant difference with respect to the non-risk group. Two cases had serious tachyarrhythmias, five worsened hemodynamic state or cyanosis, one had hemorrhage post-partum on anticoagulants and one died of a rupture of isthmic aneurysm post-coarctectomy. Prematurity occurred in 19.2% of pregnancies with cyanotic and 5.7% with acyanotic lesions. There were 6/201 recurrences of cardiac anomaly (3%). CONCLUSIONS:Patients with uncomplicated heart disease had normal course of pregnancy, while complications due to serious arrhythmias or residual hemodynamical lesions and cyanosis occurred in 4.5% of pregnancies and, mainly in 45% of those with increased risk. Thorough evaluation of the cardiologic risk is mandatory for a correct counseling of women planning pregnancy.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Fesslova' VM,Villa L,Chessa M,Butera G,Salmona S,Acaia Bdoi
10.1016/j.ijcard.2007.10.030subject
Has Abstractpub_date
2009-01-09 00:00:00pages
257-64issue
2eissn
0167-5273issn
1874-1754pii
S0167-5273(07)01963-8journal_volume
131pub_type
杂志文章abstract::Implanted defibrillators have become a mainstream therapy for the prevention of sudden cardiac death (SCD) from ventricular tachyarrhythmias in patients with chronic coronary artery disease. A decade of studies has confirmed the superiority of ICDs over antiarrhythmic drug therapy in prolonging the life of patients wi...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 信件
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pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2008-05-23 00:00:00
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pub_type: 杂志文章,meta分析,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
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更新日期:2008-06-06 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,评审
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更新日期:2005-02-28 00:00:00
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pub_type: 杂志文章
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pub_type: 临床试验,杂志文章
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更新日期:2016-08-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2017.02.013
更新日期:2017-04-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2017.02.018
更新日期:2017-08-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2013.08.030
更新日期:2013-10-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1997-07-25 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2009-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件,评审
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更新日期:2008-07-04 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2005.07.036
更新日期:2006-08-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 评论,信件
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更新日期:2008-08-29 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2018-05-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2020-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2008-09-16 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2009-10-02 00:00:00
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pub_type: 杂志文章
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更新日期:2021-01-05 00:00:00
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pub_type: 杂志文章,评审
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