Prospective evaluation from single centre of pregnancy in women with congenital heart disease.


OBJECTIVES:Study of outcomes of pregnancy in women with congenital heart disease. MATERIAL AND METHODS:The cardiac state during and after pregnancy was analysed in 173 women (mean age 28 years, range 21-41) referred for fetal echocardiography and evaluation of maternal heart during 201 pregnancies. Acyanotic lesions were present in 152 women (100 operated), in 175 pregnancies; cyanotic lesions in 21, all operated, in 26 pregnancies. Eighteen patients in 20 pregnancies (9.9% pregnancies) presented an increased risk due to severe arrhythmias or relevant residual hemodynamic lesions (risk group). RESULTS:Complications related to heart defects occurred in 9/201 (4.5%), pregnancies: in 6/175 (3.4%) pregnancies with acyanotic lesions, in 3/26 (11.5%) with cyanotic lesions and in 9/20 pregnancies of the risk group (45%), with a statistically significant difference with respect to the non-risk group. Two cases had serious tachyarrhythmias, five worsened hemodynamic state or cyanosis, one had hemorrhage post-partum on anticoagulants and one died of a rupture of isthmic aneurysm post-coarctectomy. Prematurity occurred in 19.2% of pregnancies with cyanotic and 5.7% with acyanotic lesions. There were 6/201 recurrences of cardiac anomaly (3%). CONCLUSIONS:Patients with uncomplicated heart disease had normal course of pregnancy, while complications due to serious arrhythmias or residual hemodynamical lesions and cyanosis occurred in 4.5% of pregnancies and, mainly in 45% of those with increased risk. Thorough evaluation of the cardiologic risk is mandatory for a correct counseling of women planning pregnancy.


Int J Cardiol


Fesslova' VM,Villa L,Chessa M,Butera G,Salmona S,Acaia B




Has Abstract


2009-01-09 00:00:00














  • Hypotension during exercise caused by venodilatation.

    abstract::A 54-year-old woman without organic heart disease presented with presyncopal symptoms during work. A decreased cardiac output was demonstrated by haemodynamic measurements during exercise. Treatment with fludrocortisone and ephedrine was initiated with a good haemodynamic and symptomatic result. ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Rohold A,Svanegaard J,Thayssen P

    更新日期:1990-01-01 00:00:00

  • Vessel dilator is associated with survival after acute myocardial infarction.

    abstract::To assess whether infarct size, ischemic area and/or survival correlates with circulating atrial natriuretic peptides (long acting sodium stimulator, vessel dilator, or atrial natriuretic factor), these peptides were measured in a canine model of acute myocardial infarction. Elevations in the circulating concentration...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Ackerman BH,Wyeth RP,Soulsby ME,Pappas AA,Vesely DL

    更新日期:1995-01-06 00:00:00

  • Different effect of percutaneous and surgical coronary revascularization on cardiac autonomic function and inflammation in patients with stable angina.

    abstract::We assessed heart rate variability (HRV) and high-sensitivity C-reactive protein (CRP) serum levels in 77 patients with chronic stable angina (CSA), 47 of whom had obstructive coronary artery disease (CAD) and 30 normal or near-normal coronary arteries (NCA). The effect of percutaneous coronary interventions (PCI) and...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Santangeli P,Sgueglia GA,Sestito A,Lamendola P,Mariani L,Infusino F,Niccoli G,Crea F,Lanza GA

    更新日期:2008-07-04 00:00:00

  • Hydatid disease of the right ventricle and role of tomographic scanning in its diagnosis.

    abstract::A case of hydatid cyst affecting the right ventricle is described and role of tomographic scanning highlighted as it demonstrated a typical multilocular cyst arising from the right ventricle in the patient discussed here. ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Akhtar MJ

    更新日期:1991-12-01 00:00:00

  • Atrial natriuretic peptide (ANP) suppresses acute atrial electrical remodeling in the canine rapid atrial stimulation model.

    abstract:OBJECTIVES:Atrial electrical remodeling is considered to play an important role in the appearance of atrial fibrillation. The effect of atrial natriuretic peptide (ANP) on atrial electrical remodeling was evaluated in a canine atrial stimulation model. METHODS:In 15 beagle dogs, electrodes for pacing and recording wer...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Yoshida T,Niwano S,Niwano H,Imaki R,Satoh D,Masaki Y,Nakazato K,Soma K,Izumi T

    更新日期:2008-01-11 00:00:00

  • Panoramic characterization of endocardial left atrial activation during human persistent AF: Insights from non-contact mapping.

    abstract:BACKGROUND:The relative importance of focal drivers, multiple wavelets, rotors and endocardial-epicardial circuits in the maintenance of persistent AF remains unclear. Our objective was to characterize AF wavefront (WF) dynamics during persistent AF. METHODS:The Ensite 3000 (St Jude Medical) non-contact mapping system...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Lee G,McLellan AJ,Hunter RJ,Lovell MJ,Finlay M,Ullah W,Dhinoja MB,Sporton S,Earley MJ,Schilling RJ

    更新日期:2017-02-01 00:00:00

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    abstract::A 27-year-old man with congestive heart failure due to aortic incompetence and subsequent intestinal infarction was found at laparotomy to have extensive necrosis of the bowel due to proliferative endarteritis. Symptoms resolved following treatment with prednisolone and cyclophosphamide, and replacement of the aortic ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Purvis JA,Adgey AA,O'Hara MD

    更新日期:1991-03-01 00:00:00

  • Spontaneous resolution of neoaneurysm following implantation of a paclitaxel-eluting coronary stent.

    abstract::We report a case of spontaneous resolution of neoaneurysm of the coronary artery complicating paclitaxel-eluting TAXUS stent implantation in the proximal left anterior descending artery in a 56-year-old female. ...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Kim JW,Seo HS,Suh SY,Rha SW,Park CG,Oh DJ

    更新日期:2006-09-20 00:00:00

  • Platelet reactivity in patients receiving a maintenance dose of P2Y12-ADP receptor antagonists undergoing elective percutaneous coronary intervention.

    abstract:BACKGROUND:P2Y12-ADP receptor blockade during percutaneous coronary intervention (PCI) is critical to prevent thrombotic events. In patients under chronic P2Y12 blockers, the use of additional loading dose (LD) before an elective PCI is debated. We aimed to investigate the rate of high on-treatment platelet reactivity ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Bonello L,Laine M,Thuny F,Paganelli F,Lemesle G,Roch A,Kerbaul F,Dignat-George F,Berbis J,Frere C

    更新日期:2016-08-01 00:00:00

  • The prognostic utility of dihomo-gamma-linolenic acid (DGLA) in patients with acute coronary heart disease.

    abstract:BACKGROUND:We previously investigated the prognostic utility of red blood cell (RBC) n-3 fatty acids (FAs) in survivors of an acute myocardial syndrome (ACS) but found no relationship with all-cause mortality and cardiac death or MI after two years. Here we extend our follow-up to 7years, focusing on the potential pred...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Nilsen DWT,Aarsetoey H,Pönitz V,Brugger-Andersen T,Staines H,Harris WS,Grundt H

    更新日期:2017-12-15 00:00:00

  • :Influence of the duration of Holter monitoring on the detection of arrhythmia recurrences after catheter ablation of atrial fibrillation: implications for patient follow-up.

    abstract::We investigated the influence of Holter duration on the detection of recurrences after ablation for atrial fibrillation (AF). Two-hundred-and-fifteen patients underwent a 7-day Holter ECG at 6 months after catheter ablation. We analyzed the number of patients who had a recurrence within the first 24, 48, 72 h etc. up ...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Dagres N,Kottkamp H,Piorkowski C,Weis S,Arya A,Sommer P,Bode K,Gerds-Li JH,Kremastinos DT,Hindricks G

    更新日期:2010-03-18 00:00:00

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    abstract::The alpha2-adrenoceptors (alpha2-ARs) are receptors for endogenous catecholamines (norepinephrine and epinephrine) that mediate a number of physiological and pharmacological responses such as hypotension and sedation. Three distinct subtypes, denoted alpha2A-, alpha2B- and alpha2C-AR, have been characterized and clone...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Flordellis C,Manolis A,Scheinin M,Paris H

    更新日期:2004-12-01 00:00:00

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    abstract:BACKGROUND:The use of bioprostheses for surgical aortic valve replacement increased substantially within the last years. In case of prosthesis failure, re-SAVR is standard of care, whereas valve-in-valve deployment of a transfemoral transcatheter aortic valve prosthesis (VinV-TFAVI) has recently emerged as an alternati...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Woitek FJ,Stachel G,Kiefer P,Haussig S,Leontyev S,Schlotter F,Mende M,Hommel J,Crusius L,Spindler A,Mohr FW,Schuler G,Thiele H,Borger MA,Linke A,Holzhey D,Mangner N

    更新日期:2020-02-01 00:00:00

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    abstract::The spectrum of cardiac side-effects of cancer chemotherapy has expanded with the development of combination, adjuvant and targeted chemotherapies. Their administration in multiple regimens has increased greatly, including in older patients and in patients with cardiovascular and/or coronary artery disease (CAD). Card...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Monsuez JJ,Charniot JC,Vignat N,Artigou JY

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    abstract:BACKGROUND:In addition to lowering lipid profile, statins have pleiotropic effects on improving vascular function. Changes of these pleiotropic effects and their relationship to lipid profile after withdrawal of statin treatment remained unclear. METHODS:We investigated the changes of lipid profile and plasma concentr...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Lai WT,Lee KT,Chu CS,Voon WC,Yen HW,Tsai LY,Sheu SH

    更新日期:2005-02-28 00:00:00

  • The role of red blood cells in the progression and instability of atherosclerotic plaque.

    abstract::This review attempts to present a focused summary of selected areas of the rapidly growing knowledge regarding the red blood cells role in atherosclerotic plaque progression and instability. A summary of the characteristics of the erythrocyte membranes is provided, followed by a brief review of the in vitro and in viv...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,评审


    authors: Tziakas DN,Chalikias GK,Stakos D,Boudoulas H

    更新日期:2010-06-25 00:00:00

  • The role of implantable cardioverter-defibrillators in patients with continuous flow left ventricular assist devices - A meta-analysis.

    abstract:BACKGROUND:Left ventricular assist devices (LVADs) and implantable cardioverter defibrillators (ICD) are each known to improve mortality in patients with advanced congestive heart failure (CHF). If ICDs contribute to improved survival specifically in recipients of LVADs is currently unknown. AIM:To evaluate the impact...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,meta分析


    authors: Agrawal S,Garg L,Nanda S,Sharma A,Bhatia N,Manda Y,Singh A,Fegley M,Shirani J

    更新日期:2016-11-01 00:00:00

  • A novel heart rate control model provides insights linking LF-HRV behavior to the open-loop gain.

    abstract:BACKGROUND:Low-frequency heart rate variability (LF-HRV) at rest has already been successfully modeled as self-sustained oscillations in a nonlinear control loop, but these models fail to simulate LF-HRV decreases either during aerobic exercise or in heart failure patients. Following control engineering practices, we a...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Dvir H,Bobrovsky BZ,Gabbay U

    更新日期:2013-09-20 00:00:00

  • Functional capacity and quality of life in middle-age men and women with high and low number of metabolic risk factors.

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    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Levinger I,Goodman C,Hare DL,Jerums G,Selig S

    更新日期:2009-04-03 00:00:00

  • Left atrial appendage closure with the Amplatzer™ Cardiac Plug: impact of shape and device sizing on follow-up leaks.

    abstract:BACKGROUND:The Amplatzer Cardiac Plug (ACP) is a relatively new system for left atrial appendage (LAA) closure. In general, the particular design of the device and the variability of the LAA anatomy make the sizing process challenging. The objective of our study was to analyze the impact of the shape and sizing of the ...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Freixa X,Tzikas A,Sobrino A,Chan J,Basmadjian AJ,Ibrahim R

    更新日期:2013-09-30 00:00:00

  • Medium platelet volume as a noninvasive predictor of chronic total occlusion in non-infarct artery in patients with non-ST-segment elevation myocardial infarction and multivessel coronary artery disease.

    abstract:BACKGROUND:Chronic total occlusion (CTO) in a noninfarct-related artery (non-IRA) is an independent predictor of mortality in non-ST elevation myocardial infarction (NSTEMI). Mean platelet volume (MPV) is associated with cardiovascular events in NSTEMI. Little is known about the predictors of non-IRA-CTO in patients wi...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Tajstra M,Hawranek M,Desperak P,Ciślak A,Gierlotka M,Lekston A,Poloński L,Gąsior M

    更新日期:2017-02-01 00:00:00

  • Isolated right ventricular dysfunction without myocardial infarction.

    abstract::Right ventricular (RV) infarction or dysfunction is commonly complicated with acute inferior myocardial infarction. In this report, we describe a patient with unstable angina pectoris who showed a temporary isolated RV dysfunction. The patient had total occlusion of proximal right coronary artery, including RV branch,...

    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Otsuka Y,Kawamura A,Miyazaki S

    更新日期:2008-02-20 00:00:00

  • Age, body mass index and 2-hour plasma glucose are the major determinants of blood pressure in Chinese women newly diagnosed to have glucose intolerance.

    abstract::Hypertension and diabetes frequently coexist and greatly increase cardiovascular risk. There are relatively few data on the relationship between blood pressure and plasma glucose in newly diagnosed diabetic subjects especially in Chinese. We examined the glycaemic status, blood pressure profiles and other clinical and...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Ko GT,Chan JC,Cockram CS

    更新日期:1999-04-30 00:00:00

  • Clinical features, and in-hospital and 1-year mortalities of patients with acute heart failure and severe renal dysfunction. Data from the Italian Registry IN-HF Outcome.

    abstract:BACKGROUND:Chronic renal dysfunction (RD) frequently coexists with heart failure (HF) and influences outcome. Patients with acute HF (AHF) and severe RD are frequently excluded in the trials. We characterized these subjects and assessed incidence and predictors of in-hospital and one-year mortalities. METHODS:We selec...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Cioffi G,Mortara A,Di Lenarda A,Oliva F,Lucci D,Senni M,Cacciatore G,Chinaglia A,Tarantini L,Metra M,Maggioni AP,Tavazzi L,Italian Acute Heart Failure Survey.

    更新日期:2013-10-09 00:00:00

  • Sildenafil therapy for pulmonary arterial hypertension associated with atrial septal defects.

    abstract:BACKGROUND:There is increasing evidence for beneficial effects of the type 5 phosphodiesterase inhibitor, sildenafil, in idiopathic pulmonary arterial hypertension (PAH). The effects of sildenafil in severe PAH associated with an atrial septal defect (ASD) have not been clearly delineated. METHODS:This extended case s...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Lim ZS,Salmon AP,Vettukattil JJ,Veldtman GR

    更新日期:2007-05-31 00:00:00

  • Prevalence of Takayasu arteritis in young women with acute ischemic heart disease.

    abstract:OBJECTIVES:Takayasu arteritis (TA), a systemic vasculitis typically occurring in female patients aged ≤40, can affect coronary arteries and cause ischemic heart disease (IHD). In this study, we investigated the prevalence of TA in young women presenting with IHD in the Emergency Department. METHODS:We evaluated hospit...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Cavalli G,Tomelleri A,Di Napoli D,Baldissera E,Dagna L

    更新日期:2018-02-01 00:00:00

  • A comparison study of the echocardiographic changes in hypertensive patients treated with telmisartan vs. enalapril.

    abstract:BACKGROUND:Hypertension-induced cardiac dysfunction is variable among different anti-hypertensive medications. This study compares the effects of telmisartan and enalapril on echocardiographic parameters in hypertensive patients. MATERIALS AND METHODS:This was a randomised single blinded study. Eighty hypertensive pat...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,随机对照试验


    authors: Hadi NR,Abdulzahra MS,Al-Huseini LM,Al-Aubaidy HA

    更新日期:2017-03-01 00:00:00

  • Recovery of electrophysiological parameters after conversion of atrial fibrillation.

    abstract::We investigated the recovery of electrophysiological parameters from electrical remodeling after conversion of chronic lone atrial fibrillation in humans. Clinical studies have shown that the longer atrial fibrillation lasts, the more difficult it becomes to maintain the sinus rhythm after cardioversion. To explore th...

    journal_title:International journal of cardiology

    pub_type: 杂志文章


    authors: Sato T,Mitamura H,Kurita Y,Takeshita A,Shinagawa K,Miyoshi S,Kanki H,Hara M,Takatsuki S,Soejima K,Ogawa S

    更新日期:2001-07-01 00:00:00

  • Both levosimendan and dobutamine treatments result in significant reduction of NT-proBNP levels, but levosimendan has better and prolonged neurohormonal effects than dobutamine.

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    journal_title:International journal of cardiology

    pub_type: 信件


    authors: Cavusoglu Y,Tek M,Birdane A,Ata N,Demirustu C,Gorenek B,Unalir A,Timuralp B

    更新日期:2008-07-21 00:00:00

  • Metformin and contrast-induced acute kidney injury in diabetic patients treated with primary percutaneous coronary intervention for ST segment elevation myocardial infarction: Amulticenter study.

    abstract:AIM:To analyze the association between chronic metformin treatment and the development of contrast-induced acute kidney injury (CI-AKI) after primary percutaneous coronary intervention (PCI) for ST segment elevation myocardial infarction (STEMI). METHODS:Patients with type 2 diabetes mellitus (T2DM) treated with PCI <...

    journal_title:International journal of cardiology

    pub_type: 杂志文章,多中心研究


    authors: Zeller M,Labalette-Bart M,Juliard JM,Potier L,Feldman LJ,Steg PG,Cottin Y,Roussel R

    更新日期:2016-10-01 00:00:00