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Implanted defibrillators and primary prevention of sudden cardiac death: where are we today?

Abstract：

:Implanted defibrillators have become a mainstream therapy for the prevention of sudden cardiac death (SCD) from ventricular tachyarrhythmias in patients with chronic coronary artery disease. A decade of studies has confirmed the superiority of ICDs over antiarrhythmic drug therapy in prolonging the life of patients with a prior history of sustained VT or VF. Furthermore, recent studies have examined the role of ICD therapy in the primary prophylaxis against sudden death in patients considered at high risk for ventricular tachyarrhythmias. These studies have revealed that in selected patients with the substrate of chronic coronary artery disease and a ventricular scar, ICDs lead to important relative and absolute reductions in mortality in such patients without a prior history of VT or VF. Clinicians caring for patients with chronic coronary artery disease (CAD) and severe LV dysfunction, who are at a risk of sudden cardiac death, need to carefully consider this information when managing this patient population.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Ray IB,Reddy VY

doi

10.1016/j.ijcard.2003.10.032

subject

Has Abstract

pub_date

2005-01-01 00:00:00

pages

15-20

issue

1

eissn

0167-5273

issn

1874-1754

pii

S0167527304000270

journal_volume

98

pub_type

杂志文章,评审

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