Abstract:
BACKGROUND:The trends in the IHD mortality rates vary widely across countries, reflecting the heterogeneity in the variation of the exposure to the main risk factors and in the access to different management strategies among settings. We aimed to identify model-based patterns in the time trends in IHD mortality in 50 countries from the five continents, between 1980 and 2010. METHODS AND RESULTS:Mixed models were used to identify time trends in age-standardized mortality rates (ASMR) (age group 35+years; world standard population), all including random terms for intercept, slope, quadratic and cubic. Model-based clustering was used to identify the patterns. We identified five main patterns of IHD mortality trends in the last three decades, similar for men and women. Pattern 1 had the highest ASMR and pattern 2 exhibited the most pronounced decrease in ASMR during the entire study period. Pattern 3 was characterized by an initial increase in ASMR, followed by a sharp decline. Countries in pattern 4 had the lowest ASMR throughout the study period. It was further divided into patterns 4a (consistent decrease in ASMR throughout the period of analysis) and 4b (less pronounced declines and highest rates observed mostly between 1996 and 2004). There was no correspondence between the geographic or economical grouping of the analyzed countries and the patterns found in this study. CONCLUSIONS:Our study yielded a new framework for the description, interpretation and prediction of IHD mortality trends worldwide.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Gouvinhas C,Severo M,Azevedo A,Lunet Ndoi
10.1016/j.ijcard.2013.11.004subject
Has Abstractpub_date
2014-01-01 00:00:00pages
309-14issue
3eissn
0167-5273issn
1874-1754pii
S0167-5273(13)01976-1journal_volume
170pub_type
杂志文章abstract:BACKGROUND:According to recent clinical trial data, correction of iron deficiency with intravenous (i.v.) iron has favorable outcomes on cardiac function. We evaluated whether i.v. iron treatment of anemic rats has favorable effect on the left ventricular (LV) performance and remodeling and the role of oxidative/nitros...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.03.039
更新日期:2016-06-01 00:00:00
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2007.06.072
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abstract::Percutaneous coronary interventions (PCI), including balloon angioplasty and implantation of both bare metal and drug eluting coronary stents, are associated with risk of restenosis and in-stent thrombosis. A better understanding of signals that regulate cellular proliferation, neointimal formation and vessel wall thi...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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abstract::Cardiac Magnetic Resonance (CMR) imaging has recently become a very useful tool in the diagnosis of myocarditis. We describe a patient in whom acute myocarditis was presented as an acute myocardial infarction and had an atypical course with rapid normalization of ECG abnormalities. In this case CMR imaging was essenti...
journal_title:International journal of cardiology
pub_type: 信件
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(88)90293-8
更新日期:1988-09-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2008-03-14 00:00:00
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pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2017.12.009
更新日期:2018-03-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2017.04.063
更新日期:2017-08-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/j.ijcard.2003.11.033
更新日期:2005-03-18 00:00:00
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pub_type: 杂志文章
doi:10.1016/0167-5273(93)90234-8
更新日期:1993-06-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/0167-5273(92)90295-e
更新日期:1992-09-01 00:00:00
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pub_type: 杂志文章,随机对照试验
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更新日期:2011-01-21 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1996-08-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.10.029
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2014-08-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2016.06.188
更新日期:2016-10-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析,评审
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更新日期:2015-01-01 00:00:00
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pub_type: 杂志文章,随机对照试验
doi:10.1016/j.ijcard.2010.04.093
更新日期:2011-03-17 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2018.04.128
更新日期:2018-09-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
doi:10.1016/j.ijcard.2019.03.063
更新日期:2019-07-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:1987-03-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2013.01.184
更新日期:2013-09-10 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2016-11-01 00:00:00
abstract:INTRODUCTION:The progression of aortic stenosis (AS) has been shown to be faster in patients with the metabolic syndrome. We sought to determine the relationships between blood pressure, inflammation, oxidative stress and valvular inflammation in a population of normotensive and prehypertensive patients with AS. METHO...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2009.05.054
更新日期:2010-12-03 00:00:00