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International standardization of diagnostic criteria for microvascular angina.

Abstract：

:Standardization of diagnostic criteria for ischemic symptoms due to coronary microvascular dysfunction (CMD) is needed for further investigation of patients presenting with anginal chest pain consistent with "microvascular angina" (MVA). At the annual Coronary Vasomotion Disorders International Study Group (COVADIS) Summits held in August 2014 and 2015, the following criteria were agreed upon for the investigative diagnosis of microvascular angina: (1) presence of symptoms suggestive of myocardial ischemia; (2) objective documentation of myocardial ischemia, as assessed by currently available techniques; (3) absence of obstructive CAD (<50% coronary diameter reduction and/or fractional flow reserve (FFR) >0.80) (4) confirmation of a reduced coronary blood flow reserve and/or inducible microvascular spasm. These standardized criteria provide an investigative structure for mechanistic, diagnostic, prognostic and clinical trial studies aimed at developing an evidence base needed for guidelines in this growing patient population. Standardized criteria will facilitate microvascular angina registries and recruitment of suitable patients into clinical trials. Mechanistic research will also benefit from the implementation of standardized diagnostic criteria for MVA.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Ong P,Camici PG,Beltrame JF,Crea F,Shimokawa H,Sechtem U,Kaski JC,Bairey Merz CN,Coronary Vasomotion Disorders International Study Group (COVADIS).

doi

10.1016/j.ijcard.2017.08.068

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

16-20

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(17)30812-4

journal_volume

250

pub_type

杂志文章,评审

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