Abstract:
BACKGROUND:To determine the cardiological substrate in acute stroke patients presenting with a cardioembolic stroke subtype. METHODS:Data of 402 consecutive patients with cardioembolic stroke (cerebral infarction, n=347; transient ischaemic attack, n=55) were collected from a prospective hospital-based stroke registry in which data on 2000 stroke patients over a 10-year period were included. In all patients, specific cardiac disorders were identified by physical examination and results of electrocardiography and transthoracic echocardiography. Holter monitoring and more sensitive techniques of cardiac imaging were used in selected cases. RESULTS:Cardioembolic cerebral ischaemia accounted for 20% of all acute strokes (25% of ischaemic cerebrovascular events). Cardiac sources of embolism included the following: (a) structural cardiac disorders associated with arrhythmia (n=232), the most frequent being left ventricular hypertrophic hypertensive disease (n=120) and rheumatic mitral valve disease (n=49); (b) structural cardiac disease with sustained sinus rhythm (n=81), the most frequent being systolic left ventricular dysfunction of both ischaemic (n=35) or non-ischaemic (n=24) aetiology; and (c) isolated atrial dysrhythmia (atrial fibrillation, n=88 and atrial flutter, n=1). CONCLUSIONS:Hypertrophic hypertensive cardiac disease complicated with atrial fibrillation was the most frequent cardiac source of emboli in cardioembolic stroke. Other important cardiac sources were isolated atrial fibrillation, rheumatic mitral valve disease, and systolic left ventricular dysfunction of ischaemic and non-ischaemic cause. The incidence of traditional emboligenous-prone cardiac disorders, such as mitral valve prolapse and mitral annular calcification was low.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Pujadas Capmany R,Arboix A,Casañas-Muñoz R,Anguera-Ferrando Ndoi
10.1016/j.ijcard.2003.02.007subject
Has Abstractpub_date
2004-06-01 00:00:00pages
129-34issue
2-3eissn
0167-5273issn
1874-1754pii
S0167527303003619journal_volume
95pub_type
杂志文章abstract:BACKGROUND:Definition of ischemic cardiomyopathy (IC) is not always obvious, which is why new criteria based on prognosis and the extent of the coronary artery disease (CAD) have been proposed. In the present study, we assess the capability of late gadolinium-enhanced cardiovascular magnetic resonance (CMR) for predict...
journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2006.03.040
更新日期:2007-03-20 00:00:00
abstract::We analysed clinical features and outcome in 850 patients with thromboangiitis obliterans (TAO), based on the 1993 Nationwide Survey of Vasculitis database collected from 3722 clinical sites in Japan. The survey was designed to assess clinical manifestation categorized by Fontaine's classification, distribution of les...
journal_title:International journal of cardiology
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doi:10.1016/s0167-5273(00)00190-x
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/s0167-5273(98)00179-x
更新日期:1998-10-01 00:00:00
abstract::Tachycardias mediated by atrioventricular accessory pathways, which are refractory to antiarrhythmic drug therapy have been treated both by surgery and by catheter ablation with high energy direct current shock. These procedures have variable success rates and substantial associated morbidity and mortality. Radiofrequ...
journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
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更新日期:1993-12-15 00:00:00
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journal_title:International journal of cardiology
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更新日期:2007-08-09 00:00:00
abstract:BACKGROUND:Many patients fail to receive β-blockers before cardiac resynchronization therapy defibrillator (CRT-D) implantation, or receive them at a suboptimal dose, and require optimization after implantation. We assessed the effectiveness of a structured program for β-blocker titration in CRT-D patients followed up ...
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更新日期:2017-06-01 00:00:00
abstract:BACKGROUND:Transcatheter aortic valve replacement (TAVR) is an alternative to open cardiac surgery in selected patients with severe aortic stenosis (AS). Carotid artery stenosis (CAS) has been associated with an increased risk of stroke following cardiac surgery, although the association between CAS and outcomes follow...
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.11.078
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doi:10.1016/0167-5273(88)90274-4
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journal_title:International journal of cardiology
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更新日期:2005-06-08 00:00:00
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journal_title:International journal of cardiology
pub_type: 临床试验,杂志文章
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更新日期:1998-03-13 00:00:00
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journal_title:International journal of cardiology
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更新日期:2015-07-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.07.058
更新日期:2016-10-15 00:00:00
abstract:BACKGROUND:Recent clinical trials have evaluated the cardiovascular outcomes of dipeptidyl peptidase-4 (DPP-4) inhibitors in patients with type 2 diabetes mellitus (T2DM), but those with end-stage renal disease (ESRD) were ineligible for participation in these trials. We aimed to characterize the impact of DPP-4 inhibi...
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pub_type: 杂志文章
doi:10.1016/j.ijcard.2016.05.062
更新日期:2016-09-01 00:00:00
abstract::Chronic thromboembolic pulmonary hypertension (CTEPH) is a subgroup of pulmonary hypertension that differs from all other forms of PH in terms of its pathophysiology, patient characteristics and treatment. For implementation of the European Guidelines on Diagnosis and Treatment of Pulmonary Hypertension in Germany, th...
journal_title:International journal of cardiology
pub_type: 杂志文章,评审
doi:10.1016/j.ijcard.2018.08.079
更新日期:2018-12-01 00:00:00
abstract::This study was performed to evaluate whether transoesophageal atrial pacing could also stop ventricular tachycardias with low rates and no haemodynamic impairment. Prior to resorting to ventricular endocardial pacing, seven male patients, aged between 15 and 73 years, were treated by transoesophageal atrial pacing for...
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pub_type: 杂志文章
doi:10.1016/0167-5273(90)90318-y
更新日期:1990-09-01 00:00:00
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pub_type: 杂志文章,评审
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pub_type: 杂志文章,评审
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pub_type: 临床试验,杂志文章,多中心研究
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pub_type: 杂志文章,多中心研究
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更新日期:2009-10-02 00:00:00
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pub_type: 杂志文章
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2004-03-01 00:00:00
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pub_type: 杂志文章
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更新日期:2015-04-01 00:00:00
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journal_title:International journal of cardiology
pub_type: 信件
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更新日期:2010-07-09 00:00:00
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journal_title:International journal of cardiology
pub_type: 社论
doi:
更新日期:2002-01-01 00:00:00
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更新日期:2017-08-15 00:00:00