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4D flow cardiac magnetic resonance in children and adults with congenital heart disease: Clinical experience in a high volume center.

Abstract：

BACKGROUND:Cardiac magnetic resonance (CMR) imaging with velocity encoding along all three directions of flow, known as 4DFlow CMR, provides both anatomical and functional information. Few data are available on the usefulness of 4DFlow CMR in everyday practice. Here, our objective was to investigate the usefulness of 4DFlow CMR for assessing congenital heart disease (CHD) in everyday practice. METHODS:From 2017 to 2019, consecutive patients who underwent 4DFlow CMR were included prospectively at a single high-volume centre. The parameters recommended by an expert's consensus statement for each diagnosis (congenital valvulopathy, septal defect, complex CHD, tetralogy of Fallot, aortic abnormalities) were assessed by two blinded experienced readers. 4DFlow CMRs that provided all recommended parameters were considered successful. Inter-observer and intra-observer agreement were investigated. RESULTS:We included 187 adults and 60 children covering broad ranges of weight (4.5-142 kg) and age (0.1-67 years). 4DFlow CMR was always the second-line imaging modality, after inconclusive echocardiography, and was successful in 231/247 (91%) patients, with no significant difference between children and adults (54/60, 90%; and 177/187, 95%; respectively; p = .13). Longer time using 4DFlow CMR at our centre was associated with success; in children, older age was also associated with exam success. There was an about 12-month learning curve in children. The success rate was lowest in neonates. Inter-observer and intra-observer agreement were substantial. CONCLUSION:Our results suggest that 4DFlow CMR usually provides a comprehensive assessment of CHD in adults and children. A learning curve exists for children and the investigation remains challenging in neonates.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Isorni MA,Moisson L,Moussa NB,Monnot S,Raimondi F,Roussin R,Boet A,van Aerschot I,Fournier E,Cohen S,Kara M,Hascoet S

doi

10.1016/j.ijcard.2020.07.021

subject

Has Abstract

pub_date

2020-12-01 00:00:00

pages

168-177

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(20)33469-0

journal_volume

320

pub_type

杂志文章

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