当前位置： SCI文献检索 > INTERNATIONAL JOURNAL OF CARDIOLOGY期刊下所有文献 > Heart failure and inflammation-related biomarkers as predictors of new-onset diabetes in the general population.

Heart failure and inflammation-related biomarkers as predictors of new-onset diabetes in the general population.

Abstract：

BACKGROUND:There is a strong reciprocal relationship between heart failure (HF) and diabetes mellitus (DM). Shared pathophysiological mechanisms might be a possible explanation. Therefore, we hypothesised that biomarkers linked to HF would also predict new-onset type 2 DM in the general population. METHODS AND RESULTS:We utilized the Prevention of Vascular and Renal End-stage Disease (PREVEND) cohort (mean age 48.9years, 51% female) to study the relationship between HF and DM in 7953 participants free of baseline HF and DM. Multiple HF-related, inflammation-related and renal function-related biomarkers were evaluated regarding their predictive utility in new-onset DM. Incidence of DM in participants who developed HF was 11.8%, versus 5.4% in those who had not developed HF (p<0.001). Incidence of HF in participants who developed DM was 8.5%, versus 3.8% in those who had not developed DM (p<0.001). Classical HF biomarkers, NT-proBNP and hs-TnT were not associated with an increased risk for new-onset DM. However, inflammatory biomarkers hs-CRP [hazard ratio (HR) 1.16, (95% CI 1.05 to 1.29), p=0.005], procalcitonin [HR 1.34, (95% CI 1.07 to 1.69), p=0.012] and PAI-1 [HR 1.55, (95% CI 1.37 to 1.75), p<0.001] remained significantly associated with new-onset DM, even after multivariable adjustment for established predictors of DM. CONCLUSIONS:Although HF and DM have a strong correlation with each other, systemic biomarkers that predict HF do not have a predictive value in new-onset DM. This suggests that other, indirect, pathophysiological mechanisms related to inflammation may explain their strong relation.

journal_name

Int J Cardiol

journal_title

International journal of cardiology

authors

Suthahar N,Meijers WC,Brouwers FP,Heerspink HJL,Gansevoort RT,van der Harst P,Bakker SJL,de Boer RA

doi

10.1016/j.ijcard.2017.10.035

subject

Has Abstract

pub_date

2018-01-01 00:00:00

pages

188-194

eissn

0167-5273

issn

1874-1754

pii

S0167-5273(17)34233-X

journal_volume

250

pub_type

杂志文章

相关文献

INTERNATIONAL JOURNAL OF CARDIOLOGY文献大全
  • Efficacy of intramyocardial injection of Algisyl-LVR for the treatment of ischemic heart failure in swine.

    abstract：BACKGROUND:Progressive thinning and dilation of the LV due to ischemic heart failure (IHF) increases wall stress and myocardial oxygen consumption. Injectable biopolymers implanted in the myocardial wall have been used to increase wall thickness to reduce chamber volume, decrease wall stress, and improve cardiac functi...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2017.09.179

    authors： Choy JS,Leng S,Acevedo-Bolton G,Shaul S,Fu L,Guo X,Zhong L,Guccione JM,Kassab GS

    更新日期：2018-03-15 00:00:00

  • Cerebral haemorrhage in anticoagulated patients with non-septic mechanical valvular prosthesis.

    abstract：:Cerebral haemorrhage in anticoagulated patients with mechanical valvular prosthesis poses an uncommon but difficult management problem. Four such patients are presented: one patient had delayed haemorrhagic transformation of a preexisting cerebral infarct, one probably had de novo haemorrhage complicating hypertension...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(91)90005-a

    authors： Lau CP,Chang CM,Lau GK,Wong CK,Fong PC,Yu YL

    更新日期：1991-03-01 00:00:00

  • Cardiac sarcoidosis evaluated with gadolinium-enhanced magnetic resonance and contrast-enhanced 64-slice computed tomography.

    abstract：:Sarcoidosis is a multi-system granulomatous disorder of unknown etiology with symptomatic cardiac involvement in up to 7% of patients. The clinical features of sarcoid heart disease include congestive heart failure, arrhythmias, conduction disturbances, and sudden death. We evaluated the value of contrast-enhanced mul...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2005.07.059

    authors： Smedema JP,Truter R,de Klerk PA,Zaaiman L,White L,Doubell AF

    更新日期：2006-09-20 00:00:00

  • Facilitated PCI in younger Chinese patients with AMI.

    abstract：:Presently, facilitated percutaneous coronary intervention (PCI) in patients remains controversial. We evaluated the efficacy and safety of facilitated PCI, intravenous low-dose rt-PA administration prior to urgent PCI, in Chinese patients < 70 years of age with ST-segment elevation myocardial infarction. Our results s...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2006.08.021

    authors： Xu F,Chen YG,Li JF,Li GS,Ji QS,Lv RJ,Liu TT,Sun Y,Li RJ,Zhang W,Zhang Y

    更新日期：2007-09-14 00:00:00

  • Neutrophil-derived myeloperoxidase promotes atherogenesis and neointima formation in mice.

    abstract：BACKGROUND:Myeloperoxidase (MPO), expressed mainly in neutrophils, is an enzyme linked to inflammation and oxidative stress. MPO is an independent prognostic marker in healthy individuals as well as in patients with coronary artery disease. In this present study we analyze the role of MPO in experimental atherogenesis ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2015.11.128

    authors： Tiyerili V,Camara B,Becher MU,Schrickel JW,Lütjohann D,Mollenhauer M,Baldus S,Nickenig G,Andrié RP

    更新日期：2016-02-01 00:00:00

  • Association between VO₂ peak estimated by a 1-km treadmill walk and mortality. A 10-year follow-up study in patients with cardiovascular disease.

    abstract：PURPOSE:The aim of this study is to assess the association between peak oxygen uptake (VO2 peak), determined using a perceptually regulated 1-km walking test (1k-TWT), and all-cause mortality in cardiac patients. METHODS:1255 male patients, aged 25-85 years, completed a moderate 1k-TWT to estimate VO2 peak. Subjects w...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2014.02.039

    authors： Grazzi G,Myers J,Bernardi E,Terranova F,Grossi G,Codecà L,Volpato S,Conconi F,Mazzoni G,Chiaranda G

    更新日期：2014-05-01 00:00:00

  • Transmission of calibration errors (input) by generalized transfer functions to the aortic pressures (output) at different hemodynamic states.

    abstract：BACKGROUND:Aortic pressure waveforms are calculated non-invasively by applying generalized transfer functions (GTF) to tonometric radial pressure waveforms. Input errors mainly during acquisition and calibration of tonometric pressures are "transferred" to aortic pressure calculation. The present study aimed to quantif...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2005.07.014

    authors： Papaioannou TG,Lekakis JP,Karatzis EN,Papamichael CM,Stamatelopoulos KS,Protogerou AD,Mavrikakis M,Stefanadis C

    更新日期：2006-06-07 00:00:00

  • TGFβ1 contributes to cardiomyogenic-like differentiation of human bone marrow mesenchymal stem cells.

    abstract：BACKGROUND:The majority of the protocols for cardiomyocyte differentiation of MSC use 5-azacytidine as an inducer. As transforming growth factor β1 and 5-azacytidine share similar target signaling pathways, we examined whether transforming growth factor β1 can play a role in cardiac differentiation process in human mes...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2011.08.003

    authors： Mohanty S,Bose S,Jain KG,Bhargava B,Airan B

    更新日期：2013-02-10 00:00:00

  • Association between the Ser128Arg variant of the E-selectin and risk of coronary artery disease in the central China.

    abstract：BACKGROUND:The E-selectin mediates the interaction of activated endothelial cells with leukocytes and plays a fundamental role in the pathogenesis of coronary atherosclerosis. It has been suggested that a S/R (Ser128Arg) polymorphism of E-selectin might be associated with the predisposition to coronary artery disease (...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2004.07.011

    authors： Li Y,Wei YS,Wang M,Zhang PA,Jiang XJ,Huang CX

    更新日期：2005-08-03 00:00:00

  • Relationships between positive psychological constructs and health outcomes in patients with cardiovascular disease: A systematic review.

    abstract：:Depression and anxiety are well-known to be associated with adverse health outcomes in cardiac patients. However, there has been less work synthesizing the effects of positive psychological constructs (e.g., optimism) on health-related outcomes in cardiac patients. We completed a systematic review of prospective obser...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2015.05.121

    authors： DuBois CM,Lopez OV,Beale EE,Healy BC,Boehm JK,Huffman JC

    更新日期：2015-09-15 00:00:00

  • Haemodynamic changes during dobutamine stress echocardiography in patients with and without ischaemia.

    abstract：:We studied haemodynamic changes during dobutamine stress echocardiography in 69 patients (mean age 58 years, 6 female, 63 male) referred for investigation of chest pain. We used a standard protocol of 3 min stages using infusion rates of 5, 10, 20, 30 and 40 micrograms/kg/min. Heart rate rose from 74 (13) to 123 (21) ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/s0167-5273(96)02846-x

    authors： Mishra MB,Cooke RA,Jackson G,Chambers JB

    更新日期：1997-01-03 00:00:00

  • Is left ventricular diastolic function an independent marker of prognosis after acute myocardial infarction?

    abstract：BACKGROUND:In addition to clinical risk markers, indices of left ventricular (LV) systolic function are valuable prognostic markers after acute myocardial infarction (MI). Previous studies have also suggested that LV diastolic function may contribute with prognostic information. The present study assessed whether this ...

    journal_title：International journal of cardiology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2004.05.006

    authors： Quintana M,Edner M,Kahan T,Hjemdahl P,Sollevi A,Rehnqvist N

    更新日期：2004-08-01 00:00:00

  • Detection of myosin gene expression in the developing heart using probes derived by polymerase chain reaction.

    abstract：:The polymerase chain reaction provides a rapid method for the molecular cloning of DNA probes suitable for the detection of specific messenger RNA. We have used this approach to prepare probes specific for human cardiac myosin messenger RNA and demonstrate here the use of such probes in the analysis of human cardiac d...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(91)90133-a

    authors： Barton PJ,Moscoso G,Thompson RP

    更新日期：1991-01-01 00:00:00

  • Determinants of survival and hospitalization in older, heart failure patients receiving home healthcare.

    abstract：INTRODUCTION:Since reported evidence is both scarce and controversial, the objective of this study is to determine the risk factors involved in the prognosis of older patients with heart failure (HF) receiving home healthcare from primary care professionals. METHODS:Retrospective cohort community study was carried out...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.01.170

    authors： Muñoz MA,Real J,Del Val JL,Vinyoles E,Mundet X,Frigola-Capell E,Llauger MA,Orfila F,Domingo M,Verdú-Rotellar JM

    更新日期：2016-03-15 00:00:00

  • The effects of dopexamine hydrochloride on cardiopulmonary haemodynamics following cardiopulmonary bypass surgery.

    abstract：:We studied the effects of dopexamine hydrochloride in 14 patients following cardiopulmonary bypass for coronary revascularisation (12 patients) or valve replacement (2 patients). The drug was administered by intravenous infusion at rates of 1, 2, 4 and 6 micrograms/kilogram/minute for a period of 10 minutes at each do...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(89)90197-6

    authors： Hunter DN,Gray H,Mudaliar Y,Morgan C,Evans TW

    更新日期：1989-06-01 00:00:00

  • Clinical characteristics and outcome of chronic ischemic heart failure in angina-free patients.

    abstract：:We sought to determine clinical characteristics as well as outcome of angina-free patients with chronic ischemic heart failure. In comparison with ischemic chest pain patients, angina-free patients have higher heart rate and systolic blood pressure on admission, lower number of diseased coronary artery vessels at coro...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2007.04.137

    authors： Bestetti RB,Yoshitake R,Cardoso TA,Freitas PF,Cordeiro JA,Theodoropoulos TA

    更新日期：2008-08-01 00:00:00

  • Outpatient volumes and medical staffing resources as predictors for continuity of follow-up care during transfer of adolescents with congenital heart disease.

    abstract：BACKGROUND:Providing continuous follow-up care to patients with congenital heart disease (CHD) remains a challenge in many settings. Previous studies highlight that patients with CHD experience discontinuation of follow-up care, but mainly describe a single-centre perspective, neglecting inter-institutional variations....

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2020.01.016

    authors： Skogby S,Moons P,Johansson B,Sunnegårdh J,Christersson C,Nagy E,Winberg P,Hanséus K,Trzebiatowska-Krzynska A,Fadl S,Fernlund E,Kazamia K,Rydberg A,Zühlke L,Goossens E,Bratt EL

    更新日期：2020-07-01 00:00:00

  • Detection of right ventricular myocardial fibrosis using quantitative CT attenuation of the right ventricular myocardium in the late phase on 320 slice CT in subjects with pulmonary hypertension.

    abstract：PURPOSE:Right ventricular myocardial (RVM) fibrosis may be a significant indicator of prognosis in pulmonary hypertension (PH). To detect the presence of RVM fibrosis in PH subjects, we employed ECG gated 320-slice CT. METHODS:62 confirmed PH subjects (16 males; 55±16years; 45 chronic thromboembolic PH (CTEPH) who und...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2016.11.131

    authors： Ozawa K,Funabashi N,Takaoka H,Tanabe N,Tatsumi K,Kobayashi Y

    更新日期：2017-02-01 00:00:00

  • Cannabis as a precipitant of cardiovascular emergencies.

    abstract：:Cannabis smoking is on the increase both in the United Kingdom and in the United States. For over three decades it has been known that cannabis has pathophysiological effects on the cardiovascular system, and previously an association with an increased risk of myocardial infarction has been reported. However, it is no...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2004.10.038

    authors： Lindsay AC,Foale RA,Warren O,Henry JA

    更新日期：2005-09-30 00:00:00

  • "Cardiovascular magnetic resonance imaging reveals myocardial inflammation and coronary artery ectasia during the acute phase of Kawasaki disease".

    abstract：:In a patient with Kawasaki disease, during the acute phase, cardiovascular magnetic resonance has been successfully used for simultaneous evaluation of coronary arteries, myocardial function and the presence of myocardial inflammation. This comprehensive protocol revealed clinically relevant information that was misse...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2008.05.005

    authors： Mavrogeni S,Papadopoulos G,Karanasios E,Cokkinos DV

    更新日期：2009-08-21 00:00:00

  • Anthracycline-induced cardiomyopathy: favourable effects of cardiac resynchronization therapy.

    abstract：:We report a case of severe refractory congestive heart failure after anthracycline chemotherapy in a patient with a narrow QRS interval on the electrocardiogram and echocardiographic evidence of left ventricular dyssynchrony, where cardiac resynchronization therapy resulted in normalization of left ventricular ejectio...

    journal_title：International journal of cardiology

    pub_type： 信件

    doi：10.1016/j.ijcard.2008.11.194

    authors： Ahlehoff O,Galløe AM,Hansen PR

    更新日期：2010-07-09 00:00:00

  • Anomalous drainage of the right superior vena cava into the left atrium in a 61-year-old woman.

    abstract：:This report describes a 61-year-old female with an anomalous drainage of the right superior vena cava into the left atrium. The patient presented progressively severe dyspnea and precordial pain on exertion, lightheadedness, easy fatiguability and a constant decline in her performance but normal cardiac and pulmonary ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/s0167-5273(98)00054-0

    authors： Rosenkranz S,Stäblein A,Deutsch HJ,Verhoeven HW,Erdmann E

    更新日期：1998-05-15 00:00:00

  • Outcomes of patients with chronic kidney disease and implantable cardiac defibrillator: primary versus secondary prevention.

    abstract：BACKGROUND:Chronic kidney disease (CKD) is associated with worse survival in patients with implantable cardiac defibrillators (ICDs). This study examined the association of outcomes with CKD in patients receiving an ICD for primary versus secondary prevention. METHODS:The study included 696 patients who underwent ICD ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2011.07.087

    authors： Hage FG,Aljaroudi W,Aggarwal H,Bhatia V,Miller J,Doppalapudi H,Wazni O,Iskandrian AE

    更新日期：2013-04-30 00:00:00

  • Pacing in congenital heart disease - A four-decade experience in a single tertiary centre.

    abstract：BACKGROUND:The increased risk of brady- and tachy-arrhythmias in the congenital heart disease (CHD) population means that cardiac rhythm management devices are often required at an early age and expose patients to device-related complications. The present study drew upon four decades of experience at a tertiary adult c...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2017.02.151

    authors： Midha D,Chen Z,Jones DG,Williams HJ,Lascelles K,Jarman J,Clague J,Till J,Dimopoulos K,Babu-Narayan SV,Markides V,Gatzoulis MA,Wong T

    更新日期：2017-08-15 00:00:00

  • Cangrelor compared with clopidogrel in patients with prior myocardial infarction - Insights from the CHAMPION trials.

    abstract：BACKGROUND:Patients who have had a prior myocardial infarction (MI) are at increased risk for adverse outcomes after subsequent percutaneous coronary intervention (PCI). OBJECTIVE:The objective of this study is to examine the efficacy and safety of cangrelor, a potent intravenous P2Y12 inhibitor, in patients with prio...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.ijcard.2017.10.006

    authors： Eisen A,Harrington RA,Stone GW,Steg PG,Gibson CM,Hamm CW,Price MJ,Prats J,Deliargyris EN,Mahaffey KW,White HD,Bhatt DL,CHAMPION Investigators.

    更新日期：2018-01-01 00:00:00

  • Management of massive air embolism during open heart surgery.

    abstract：:Two patients in whom a massive bolus of air was introduced into the arterial circuit and ascending aorta during valve replacement and in whom the recovery was complete are presented. The technical details of the management of this serious accident are described. ...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/0167-5273(85)90236-0

    authors： Kumar AS,Jayalakshmi TS,Kale SC,Saxena BK,Singh V,Paul SJ

    更新日期：1985-12-01 00:00:00

  • Antidepressant use before coronary artery bypass surgery is associated with long-term mortality.

    abstract：BACKGROUND:Depression is common in patients with coronary artery disease and is associated with increased cardiovascular morbidity and mortality. Previous reports on the relationship between antidepressant use before coronary artery bypass grafting (CABG) and survival are conflicting. Our aim was to study the associati...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2012.08.010

    authors： Stenman M,Holzmann MJ,Sartipy U

    更新日期：2013-09-10 00:00:00

  • A systematic review of the effectiveness of oral health promotion activities among patients with cardiovascular disease.

    abstract：AIMS:This study aimed to review the effectiveness of oral health promotion activities conducted among patients with cardiovascular disease. METHODS AND RESULTS:Three electronic databases were searched for effective papers using standardized search methods, and key findings of effective studies were summarized. The ini...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,评审

    doi：10.1016/j.ijcard.2010.11.014

    authors： Lam OL,Zhang W,Samaranayake LP,Li LS,McGrath C

    更新日期：2011-09-15 00:00:00

  • Altered autonomic neural control of the cardiovascular system in patients with polycystic ovary syndrome.

    abstract：PURPOSE:Polycystic ovary syndrome (PCOS) is frequently accompanied by the presence of cardiovascular risk factors. It has also been recognized that there is a significant relationship between the autonomic nervous system and adverse cardiac events. Heart rate recovery (HRR) after exercise is a marker of parasympathetic...

    journal_title：International journal of cardiology

    pub_type： 杂志文章

    doi：10.1016/j.ijcard.2007.08.037

    authors： Tekin G,Tekin A,Kiliçarslan EB,Haydardedeoğlu B,Katircibaşi T,Koçum T,Erol T,Cölkesen Y,Sezgin AT,Müderrisoğlu H

    更新日期：2008-10-30 00:00:00

  • Metabolic syndrome and insulin resistance are associated with abnormal left ventricular diastolic function and structure independent of blood pressure and fasting plasma glucose level.

    abstract：BACKGROUND:Abnormal left ventricular (LV) structure and diastolic function are frequently detected in a variety of heart diseases, and insulin resistance has been suggested to be associated with LV diastolic dysfunction (LVDD). The aims of this study were to determine the association between LVDD or LV structure and me...

    journal_title：International journal of cardiology

    pub_type： 杂志文章,多中心研究

    doi：10.1016/j.ijcard.2011.02.039

    authors： Hwang YC,Jee JH,Kang M,Rhee EJ,Sung J,Lee MK

    更新日期：2012-08-23 00:00:00