Abstract:
INTRODUCTION:We conducted a meta-analysis of randomized, controlled trials of combined electrical stimulation versus conventional exercise training or placebo control in heart failure patients. METHODS:A systematic search was conducted of Medline (Ovid) (1950-September 2011), Embase.com (1974-September 2011), Cochrane Central Register of Controlled Trials and CINAHL (1981-September 2011). The search strategy included a mix of MeSH and free text terms for the key concepts heart failure, exercise training and functional electrical stimulation (FES). RESULTS:FES produced inferior improvements in peak VO2 when compared to cycle training: mean difference (MD) -0.32 ml.kg(-1).min(-1) (95% C.I. -0.63 to -0.02 ml.kg(-1).min(-1), p=0.04), however FES elicited superior improvements in peak VO2: MD 2.30 ml.kg(-1).min(-1) (95% C.I. 1.98 to 2.62 ml.kg(-1).min(-1), p<0.00001); and six minute walk distance to sedentary care or sham FES; MD 46.9 m (95% C.I. 22.5 to 71.3m, p=0.0002). There was no difference in change in quality of life between cycling and FES, but FES elicited significantly larger improvements in Minnesota Living with Heart Failure score than placebo or sham treatment; MD 1.15 (95% C.I. 0.69 to 1.61, p<0.00001). Moreover, the total FES intervention hours were strongly correlated with change in peak VO2, (r=0.80, p=0.02). CONCLUSIONS:Passive or active exercise is beneficial for patients with moderate to severe heart failure, but active cycling, or other aerobic/resistance activity is preferred in patients with heart failure who are able to exercise, and FES is the preferred modality in those unable to actively exercise. The benefits of FES may however, be smaller than those observed in conventional exercise training. Aggregate hours of electrical stimulation therapy were associated with larger improvements in cardio-respiratory fitness.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Smart NA,Dieberg G,Giallauria Fdoi
10.1016/j.ijcard.2011.12.019subject
Has Abstractpub_date
2013-07-15 00:00:00pages
80-6issue
1eissn
0167-5273issn
1874-1754pii
S0167-5273(11)02183-8journal_volume
167pub_type
杂志文章,meta分析,评审abstract::Left ventricular (LV) aneurysm has been recognized to frequently become a substrate of ventricular tachyarrhythmias. We report a case of a 66-year-old woman with symptomatic sustained monomorphic ventricular tachycardia (SMVT) originating from saccular apical LV aneurysm without definite underlying diseases. We perfor...
journal_title:International journal of cardiology
pub_type: 信件
doi:10.1016/S0167-5273(03)00222-5
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abstract::Although increasing hypertension rates have been reported in several African populations, little is known about the frequency of resulting hypertensive complications in these populations. We recorded the electrocardiograms of 482 male and 284 female civil servants in Benin City, Nigeria. Five different criteria were u...
journal_title:International journal of cardiology
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pub_type: 杂志文章,多中心研究
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journal_title:International journal of cardiology
pub_type: 杂志文章
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pub_type: 社论
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pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章,评审
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究
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journal_title:International journal of cardiology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.ijcard.2016.10.080
更新日期:2017-01-15 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章,meta分析
doi:10.1016/j.ijcard.2012.05.008
更新日期:2013-09-01 00:00:00
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pub_type: 信件
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更新日期:2010-06-25 00:00:00
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pub_type: 杂志文章
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pub_type: 杂志文章
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更新日期:2020-09-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2016-11-01 00:00:00
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journal_title:International journal of cardiology
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pub_type: 信件
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pub_type: 杂志文章
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pub_type: 信件
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journal_title:International journal of cardiology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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pub_type: 信件
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pub_type: 信件
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更新日期:2009-02-06 00:00:00
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journal_title:International journal of cardiology
pub_type: 杂志文章
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更新日期:2015-02-15 00:00:00