Abstract：
:Asynchronous depolarization and contraction sequence, secondary to intraventricular conduction defects or to permanent right ventricular apical pacing, is associated with adverse effects that may be clinically evident in the failing heart. Experimental and clinical studies have suggested that asynchronous ventricular contraction deteriorates left ventricular performance and induces unfavourable left ventricular remodelling. Although such contraction does not appear to affect resting coronary artery blood flow, it increases endomyocardial pressure during diastole and decreases regional myocardial perfusion in the interventricular septum. The magnitude of these effects may correlate with the duration of the asynchrony. Despite these detrimental effects, there is no evidence that ventricular asynchrony reduces collateral myocardial blood flow, myocardial oxygen consumption or cardiac efficiency, neither in patients with normal coronary arteries, nor in patients with coronary artery disease. Furthermore, in patients with acute ischaemic syndromes, ventricular asynchrony exerts a neutral effect on the ischaemic myocardium. Cardiac resynchronization therapy improves left ventricular systolic and diastolic function without an increase in myocardial oxygen consumption or energy cost. This therapy may decrease the inhomogeneity in regional oxidative metabolism, myocardial perfusion and cardiac efficiency. Further experimental and clinical studies are needed on this area.
journal_name
Int J Cardioljournal_title
International journal of cardiologyauthors
Kyriakides ZS,Manolis AG,Kolettis TMdoi
10.1016/j.ijcard.2006.03.091subject
Has Abstractpub_date
2007-06-25 00:00:00pages
3-9issue
1eissn
0167-5273issn
1874-1754pii
S0167-5273(06)00988-0journal_volume
119pub_type
杂志文章,评审abstract：INTRODUCTION:A number of challenges can affect long-term performance of endocardial implanted systems in pediatric patients. Select Secure™ lead offers potential advantages for this population. This analysis aims to evaluate long-term performance of this lead in children, with and without congenital heart disease. MET...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.01.007
更新日期：2018-03-15 00:00:00
abstract：BACKGROUND:Doxorubicin (DOXO) is an effective anti-neoplastic drug but its clinical benefits are hampered by cardiotoxicity. Oxidative stress, apoptosis and myocardial fibrosis mediate the anthracycline cardiomyopathy. ROS trigger TGF-β pathway that activates cardiac fibroblasts promoting fibrosis. Myocardial stiffness...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2015.12.008
更新日期：2016-02-15 00:00:00
abstract：:Acute myocardial infarction during pregnancy is rare but may be associated with high risk complications. We present a very rare case about an acute myocardial infarction with anterior ST elevation in a 40-year-old woman, at 38th week of gestational period. The coronary arteriograms showed a diffuse left coronary vasos...
journal_title：International journal of cardiology
pub_type： 信件,评审
doi：10.1016/j.ijcard.2006.01.016
更新日期：2007-01-31 00:00:00
abstract：BACKGROUND:Lipid-lowering agents are known to reduce long-term mortality in patients with stable angina or multiple risk factors. However, the effects of lipid-lowering treatment on inflammatory process during and immediately after the acute phase of unstable angina remain unclear. In this study we assessed the effects...
journal_title：International journal of cardiology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.ijcard.2005.05.055
更新日期：2006-04-28 00:00:00
abstract：BACKGROUND:In the end of the last century arterial switch operation (ASO) replaced atrial redirection according to Senning or Mustard as the surgical technique for infants with transposition of the great arteries (TGA). Better survival with the new technique has been shown. However, exercise performance and quality of ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2011.10.116
更新日期：2013-06-20 00:00:00
abstract：BACKGROUND:Multi-antibiotic resistance in bacterial infections is a growing threat to public health. Some experiments were carried out to study the multi-antibiotic resistance. METHODS:The changes of the multi-antibiotic resistance with time were achieved by numerical simulations and the mathematical models, with the ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.05.069
更新日期：2016-09-15 00:00:00
abstract：:The recent death of a popular politician in India was followed by a spate of sudden deaths. In this letter, we analyze the deaths as reported in newspapers, and try to arrive at a reason for this strange phenomenon. ...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.09.475
更新日期：2010-11-19 00:00:00
abstract：BACKGROUND:Heart failure with preserved ejection fraction (HFpEF) is among the most common forms of heart failure (HF). We aimed to investigate the prognostic significance of serum potassium levels and its interaction with type-2 diabetes mellitus in patients with HFpEF. METHODS:Consecutive HFpEF patients were prospec...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.04.029
更新日期：2020-10-15 00:00:00
abstract：:Left ventricular outflow tract obstruction caused by a discrete subaortic membrane in a young female was successfully dilated using an Inoue balloon catheter. The Inoue balloon catheter was used in a retrograde manner via the femoral artery. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(96)02579-x
更新日期：1996-04-19 00:00:00
abstract：BACKGROUND:Heart failure (HF) is a major healthcare problem contributing significantly to hospital admission stays and National Health Service (NHS) spending. Reducing length of hospital stay (LoS) in HF is paramount in reducing this burden and is influenced by factors relating to the condition, sociodemographics and c...
journal_title：International journal of cardiology
pub_type： 杂志文章,多中心研究
doi：10.1016/j.ijcard.2016.01.132
更新日期：2016-03-15 00:00:00
abstract：:The effect and choice of a drug to control heart rate for symptomatic improvement in patients with isolated mitral stenosis with normal sinus rhythm (n = 10) or atrial fibrillation (n = 10) were studied. Digoxin (0.25-0.5 mg daily), metoprolol (50-100 mg twice a day) and verapamil (40-80 mg three times a day) were eva...
journal_title：International journal of cardiology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0167-5273(89)90223-4
更新日期：1989-12-01 00:00:00
abstract：:Levosimendan and dobutamine are comparable inotropic drugs as regards their hemodynamic effects and clinical outcomes in decompensated heart failure (HF). The aim of this study was to compare the effects of levosimendan and dobutamine treatment on NT-proBNP levels in patients with decompensated HF. Forty-four patients...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.06.136
更新日期：2008-07-21 00:00:00
abstract：BACKGROUND:Timing of surgery for mitral regurgitation (MR) is one of the more difficult decisions for the practicing cardiologist. METHODS AND RESULTS:In order to determine useful clinical cut-offs, we investigated the influence of baseline echocardiographic predictors for survival in a long-time follow-up cohort. Dat...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2008.06.037
更新日期：2009-10-02 00:00:00
abstract：INTRODUCTION:Sports activity has been associated with the development of atrial arrhythmias. Atrial fibrillation (AF) is frequently observed after successful ablation for atrial flutter. Sports activity as a risk factor for AF development after flutter ablation has not been studied. METHODS:We analyzed outcome in 137 ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2005.02.043
更新日期：2006-02-08 00:00:00
abstract：AIMS:Cardiac rehabilitation (CR) improves morbidity and mortality. Uptake varies for patients following acute coronary syndrome (ACS). Entry into CR is often dependent on the management strategy received, lower following percutaneous coronary intervention (PCI), higher following coronary artery bypass grafting (CABG). ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.11.005
更新日期：2020-11-10 00:00:00
abstract：BACKGROUND:Providing continuous follow-up care to patients with congenital heart disease (CHD) remains a challenge in many settings. Previous studies highlight that patients with CHD experience discontinuation of follow-up care, but mainly describe a single-centre perspective, neglecting inter-institutional variations....
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.01.016
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:The relative importance of focal drivers, multiple wavelets, rotors and endocardial-epicardial circuits in the maintenance of persistent AF remains unclear. Our objective was to characterize AF wavefront (WF) dynamics during persistent AF. METHODS:The Ensite 3000 (St Jude Medical) non-contact mapping system...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2016.11.085
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVES:Study of outcomes of pregnancy in women with congenital heart disease. MATERIAL AND METHODS:The cardiac state during and after pregnancy was analysed in 173 women (mean age 28 years, range 21-41) referred for fetal echocardiography and evaluation of maternal heart during 201 pregnancies. Acyanotic lesions w...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2007.10.030
更新日期：2009-01-09 00:00:00
abstract：:Relapsing polychondritis is a rare disease characterized by recurrent inflammatory lesions involving cartilaginous structures, the eyes, the ears and the cardiovascular system. Valvar insufficiency represents the most common of the cardiac abnormalities and appears in 8 percent of patients. We describe two patients ha...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(87)90214-2
更新日期：1987-03-01 00:00:00
abstract：:It is common practice to hospitalize patients with chest pain for a period of observation and to perform further diagnostic evaluation such as exercise treadmill testing (ETT) once acute myocardial infarction (AMI) has been excluded. This study evaluates the safety and efficacy of immediate ETT for patients admitted t...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(00)00338-7
更新日期：2000-09-15 00:00:00
abstract：:Implanted defibrillators have become a mainstream therapy for the prevention of sudden cardiac death (SCD) from ventricular tachyarrhythmias in patients with chronic coronary artery disease. A decade of studies has confirmed the superiority of ICDs over antiarrhythmic drug therapy in prolonging the life of patients wi...
journal_title：International journal of cardiology
pub_type： 杂志文章,评审
doi：10.1016/j.ijcard.2003.10.032
更新日期：2005-01-01 00:00:00
abstract：:No-reflow phenomenon is associated with a poor prognosis and its underlying mechanisms are still poorly understood. von Willebrand Factor (vWF) is a central molecule in haemostasis which plays an important role in acute coronary syndromes. However its possible role in no-reflow has not been assessed prior to this stud...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2009.07.046
更新日期：2010-11-19 00:00:00
abstract：:In a newborn infant with a complex congenital heart disease, a right modified Blalock-Taussig anastomosis was created because of the pulmonary atresia. A 4-mm Gore-Tex tube was inadvertently connected to the upper right pulmonary vein. Clinical signs of an arteriovenous fistula with no improvement in oxygen saturation...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(94)90137-6
更新日期：1994-11-01 00:00:00
abstract：BACKGROUND:Incidence and prognostic impact of heart failure (HF) progression has been not well addressed. METHODS:From 2009 until 2015, consecutive ambulatory HF patients were recruited. HF progression was defined by the presence of at least two of the following criteria: step up of ≥1 New York Heart Association (NYHA...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2018.08.049
更新日期：2019-02-15 00:00:00
abstract：:Right ventricular infarction (RVI) occurs in approximately 50% of patients with inferior myocardial infarction (MI). The assessment of RVI is important for identifying patients being at increased risk of in hospital mortality and poorer prognosis if impaired right ventricular (RV) systolic function is present. We repo...
journal_title：International journal of cardiology
pub_type： 信件
doi：10.1016/j.ijcard.2007.05.047
更新日期：2008-07-21 00:00:00
abstract：:Blood flow velocities were recorded using Doppler ultrasound in 40 babies aged between 1 day and 4 weeks who had coarctation of the aorta or interruption of the aortic arch. High velocity jets of 3 m/sec or more in the descending aorta were detected in only 3 patients, two of whom had interruption of the aortic arch. ...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(89)90333-1
更新日期：1989-04-01 00:00:00
abstract：:Although Hippocrates (460-c.375 BC) has been traditionally recognized as the Father of Medicine, the fact that he was seminal in the development of cardiology is much less well known. Evidence is presented to support the notion that Hippocrates could also be considered the Father of Cardiology. Hippocrates also had ma...
journal_title：International journal of cardiology
pub_type： 传,历史文章,杂志文章
doi：10.1016/s0167-5273(01)00571-x
更新日期：2001-12-01 00:00:00
abstract：:We report a case of a criss-cross heart in a 6-month-old male child with echocardiographic and angiocardiographic findings of concordant atrioventricular and discordant ventriculoarterial connexions and an intact ventricular septum. This entity has been described with a ventricular septal defect as part of its own ana...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/0167-5273(90)90102-b
更新日期：1990-03-01 00:00:00
abstract：BACKGROUND:We assessed the association between multiple meteorological factors and air pollutants and the number of acute myocardial infarction (AMI) cases using a multi-step process. METHODS:Daily AMI hospitalizations matched with 16 meteorological factors and air pollutants in 7 metropolitan provinces of the Republi...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/j.ijcard.2020.08.060
更新日期：2021-01-01 00:00:00
abstract：:Eight children, age between 4.5 and 19 years were treated with moricizine for supraventricular tachycardia during the last 3 years. The tachycardia was documented by surface electrocardiogram (ECG), and/or by ambulatory ECG in all the children and the mechanism of tachycardia was determined by previously published sur...
journal_title：International journal of cardiology
pub_type： 杂志文章
doi：10.1016/s0167-5273(96)02763-5
更新日期：1996-11-15 00:00:00
