Influence of fluoride on rat kidney antioxidant system: effects of methionine and vitamin E.


:The aim of the study has been to determine and compare the influence upon the kidney antioxidative system, exercised by administration of vitamin E, and vitamin E in combination with methionine, under conditions of oxidative stress induced by sodium fluoride. The experiment was carried out on Wistar FL rats (adult males) that, for 35 days, were administered water, NaF, NaF with vitamin E, or vitamin E with methionine (doses: 10 mg NaF/kg of body mass/24 h, 3 mg vitamin E per 10 microl per rat for 24 h, 2 mg methionine per rat for 24 h). The influence of administered sodium fluoride and antioxidants upon the antioxidative system in kidney was examined by analyzing the concentration of malondialdehyde (MDA) and the activity of the most important antioxidative enzymes (SOD, total and both its isoenzymes, GPX, GST, GR, and CAT). The studies carried out confirmed the disadvantageous effect of the administered dose of NaF upon the antixodiative system in rats (increase in the concentration MDA, decrease activity of all antioxidative enzymes). The administration of vitamin E increased the activity of studied enzymes with the exception of glutathione reductase GR; it also reduced the processes of lipid peroxidation. It has been found that combined doses of vitamin E and methionine were most effective in inhibiting lipid peroxidation processes. The results confirmed the antioxidative properties of methionine.


Biol Trace Elem Res


Błaszczyk I,Grucka-Mamczar E,Kasperczyk S,Birkner E




Has Abstract


2008-01-01 00:00:00












  • The Expression of Zinc Transporters Changed in the Intestine of Weaned Pigs Exposed to Zinc Chitosan Chelate.

    abstract::This study was conducted to investigate the effect of zinc chitosan chelate (CS-Zn) on zinc transporter expression and content of tissue zinc in weaned piglets. A total of 90 weaned pigs (Duroc × Landrace × Yorkshire) were randomly allocated to treatment groups with supplementation of 100 mg/kg zinc as ZnSO4, 100 mg/k...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Lv M,Fu X,Hu L,Yue X,Han X

    更新日期:2016-12-01 00:00:00

  • Biological monitoring, by in vivo XRF measurements, of occupational exposure to lead, cadmium, and mercury.

    abstract::In vivo X-ray fluorescence (XRF) techniques were used for biological monitoring of lead, cadmium, and mercury. Lead accumulates in bone, the level of which may thus be used for monitoring of exposure. However, there was no close association between lead levels in bone and exposure time, partly because of differences i...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Skerfving S,Christoffersson JO,Schütz A,Welinder H,Spång G,Ahlgren L,Mattsson S

    更新日期:1987-08-01 00:00:00

  • Developmental Neurotoxicity of Arsenic: Involvement of Oxidative Stress and Mitochondrial Functions.

    abstract::Over the last decade, there has been an increased concern about the health risks from exposure to arsenic at low doses, because of their neurotoxic effects on the developing brain. The exact mechanism underlying arsenic-induced neurotoxicity during sensitive periods of brain development remains unclear, although enhan...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Chandravanshi LP,Gupta R,Shukla RK

    更新日期:2018-11-01 00:00:00

  • Metal determination by EDXRF in lichens. A contribution to pollutants monitoring.

    abstract::Samples of Evernia prunastri, collected in a mountainous zone, were exposed in urban and highly industrialized areas in order to monitor the atmospheric pollution. Amounts of Cr, Mn, Fe, Ni, Cu, Zn, and Pb were determined by EDXRF spectrometry in secondary target excitation mode and in the thin film approach. An incre...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Caniglia G,Calliari I,Celin L,Tollardo AM

    更新日期:1994-10-01 00:00:00

  • Effects of nutrition on zinc, folic acid, and vitamin B12 levels during pregnancy.

    abstract::In this article, we report the results of a case control study carried out on 290 Turkish pregnant women at 5-24 wk of gestation to determine their zinc, folic acid, and vitamin B12 levels in relation to their nutritional and socioeconomic status. The women were divided into two groups (n=145 each), depending on the s...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Erdogan M,Ustüner I,Cengiz B,Söylemez F,Cavdar AO

    更新日期:2006-02-01 00:00:00

  • Selenium-dependent glutathione peroxidase modules encoded by RNA viruses.

    abstract::Glutathione peroxidase (GPx) is the prototypical eukaryotic selenoprotein, with the rare amino acid selenocysteine (Sec) at the enzyme active site, encoded by the UGA codon in RNA. A DNA virus, Molluscum contagiosum, has now been shown to encode a functional selenium-dependent GPx enzyme. Using modifications of conven...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zhang W,Ramanathan CS,Nadimpalli RG,Bhat AA,Cox AG,Taylor EW

    更新日期:1999-11-01 00:00:00

  • Mercury, Lead, Cadmium, and Barium Levels in Human Breast Milk and Factors Affecting Their Concentrations in Hamadan, Iran.

    abstract::Breast milk is considered the best source of nutrition for all infants. However, exposure of newborns to toxic metals is of special interest due to their potential harmful effects. Thus, the primary aims of this study were to determine the concentration of toxic heavy metals including lead, mercury, cadmium, and bariu...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Vahidinia A,Samiee F,Faradmal J,Rahmani A,Taravati Javad M,Leili M

    更新日期:2019-01-01 00:00:00

  • Fluoride and Biological Calcification I: Effect of Fluoride on Collagen-Induced In Vitro Mineralization and Demineralization Reactions.

    abstract::An in vitro system employing collagen isolated from the sheep tendons to induce mineralization and demineralization reactions was used not only to study the effect of various concentrations of fluoride on the collagen-induced mineralization and demineralization reactions but also to compare their action with the inhib...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Kakkar M,Kapoor V,Singla SK,Jethi RK

    更新日期:2020-08-27 00:00:00

  • Selenium Nanoparticles Act Potentially on the Growth Performance, Hemato-Biochemical Indices, Antioxidative, and Immune-Related Genes of European Seabass (Dicentrarchus labrax).

    abstract::The current study investigated the role of selenium (Se) nanoparticles on the growth performance, hemato-biochemical indices, antioxidative, and immune-related genes of European seabass (Dicentrarchus labrax). Therefore, fish with initial weight of 20.53 ± 0.10 g/fish were fed diets with 0, 0.25, 0.5, and 1 mg Se nano...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Abd El-Kader MF,Fath El-Bab AF,Abd-Elghany MF,Abdel-Warith AA,Younis EM,Dawood MAO

    更新日期:2020-10-15 00:00:00

  • Selenite or selenomethionine interaction with methylmercury on uptake and toxicity showing a weak selenite protection: studies on cultured K-562 cells.

    abstract::Selenium and methylmercuric chloride (MMC) interactions regarding cellular uptake and selenium protection on MMC toxicity have been studied. Human K-562 cells were pretreated or simultaneously treated with either selenite (5 or 50 microM) or selenomethionine (10 or 50 microM) together with (3.5 or 5 microM) MMC. Cells...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Frisk P,Yaqob A,Nilsson K,Lindh U

    更新日期:2001-06-01 00:00:00

  • Effect of oral aluminum and aluminum citrate on blood level and short-term tissue distribution of aluminum in the rat.

    abstract::Aluminum (Al) absorption seems to be very low, but many factors can enhance it in animals and humans. In the present study, we investigated the acute effect of Na citrate on Al absorption by monitoring Al levels in blood and several tissues. For this purpose, 18 Wistar male rats were divided into 3 groups: control, Al...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Deng Z,Coudray C,Gouzoux L,Mazur A,Rayssiguier Y,Pépin D

    更新日期:1998-08-01 00:00:00

  • Iodine Deficiency as Assessed by Neonatal TSH in a Sample of Mother-and-Newborn Pairs in Jiangsu Province, China.

    abstract::China has eliminated iodine deficiency disorders since 2011 via the implementation of universal salt iodisation. Following this, a new revised salt iodisation policy was introduced to reduce iodine content in table salt. Since maternal iodine deficiency can lead to cognitive impairment and cretinism in infants, the ai...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Zhou H,Lu Y,Pan B,Zhao Q,Ma ZF

    更新日期:2021-01-01 00:00:00

  • Risk Assessment of Metal(Loid)s Exposed to Infants via Consumption of Weaning Foods from Different Supermarkets in Sheffield, UK.

    abstract::Infant complementary foods are readily available in the UK markets and nowadays, weaning mothers prefer feeding their babies with these products due to modern lifestyles. However, there is a dearth of research with respect to the health risk assessment of trace essential and potentially toxic elements in these product...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Ajala LO,Obasi NA,Okafor MC,Onwukeme VI

    更新日期:2020-07-16 00:00:00

  • Microsomal membrane peroxidation by an Fe3+/paraquat system. Consequences of phenobarbital induction.

    abstract::Descriptions of the effects of paraquat (P2+) on the peroxidation of liver microsomes are very divergent. Therefore, the presence of ferric iron in the medium and the activity of microsomal mixed-function oxidase system are two factors that we have taken into consideration to explain the discrepancies. The results sho...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Fernandez Y,Subirade I,Anglade F,Periquet A,Mitjavila S

    更新日期:1995-01-01 00:00:00

  • Selenium and mercury in native and introduced fish species of patagonian lakes, Argentina.

    abstract::A survey of mercury (Hg) and selenium (Se) contents was performed in fish collected from lakes located in two National Parks of the northern patagonian Andean range. Two native species, catfish (Diplomystes viedmensis) and creole perch (Percichthys trucha), and three introduced species, brown trout (Salmo trutta), rai...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Arribére MA,Ribeiro Guevara S,Bubach DF,Arcagni M,Vigliano PH

    更新日期:2008-04-01 00:00:00

  • Association of headaches and the metals.

    abstract::Lack of specific markers constitutes a problem during diagnosis of headache syndromes. Recently, some metals have gained importance as biological parameters for the diagnosis and during treatment. Low-ionized Mg and high-ionized Ca/Mg in patients with daily migrainous headaches were noted. The blood Na level was shown...

    journal_title:Biological trace element research

    pub_type: 杂志文章,评审


    authors: Donma O,Donma MM

    更新日期:2002-01-01 00:00:00

  • Effect of Time Interval on Arsenic Toxicity to Paddy Field Cyanobacteria as Evident by Nitrogen Metabolism, Biochemical Constituent, and Exopolysaccharide Content.

    abstract::Arsenic poisoning in aquatic ecosystem is a global concern that obstructs the productivity of agricultural lands (paddy fields) by targeting the growth of cyanobacteria. The cyanobacteria also tolerate and accumulate elevated concentration of arsenic (As) inside the cell and excrete out from cells in less toxic forms ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Patel A,Tiwari S,Prasad SM

    更新日期:2020-08-06 00:00:00

  • Presence of Toxic Heavy Metals in Platelet-Rich Fibrin: a Pilot Study.

    abstract::Platelet-rich fibrin (PRF) is widely used blood-derived biomaterial which is directly applied to the surgical wounds. Depending on its autologous origin, PRF is thought as a safe material. However, it is not known to what extent the blood-derived toxins can be found in the PRF by considering the systemic exposure rate...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Yaprak E,Yolcubal İ

    更新日期:2019-10-01 00:00:00

  • The effect of a moderate zinc deficiency and dietary fat source on the activity and expression of the Δ(3)Δ (2)-enoyl-CoA isomerase in the liver of growing rats.

    abstract::Auxiliary enzymes participate in β-oxidation of unsaturated fatty acids. The objective of the study was to investigate the impact of a moderate zinc deficiency and a high intake of polyunsaturated fat on Δ(3)Δ(2)-enoyl-CoA isomerase (ECI) in the liver and other tissues. Five groups of eight weanling rats each were fed...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Justus J,Weigand E

    更新日期:2014-06-01 00:00:00

  • Effect of High Dietary Manganese on the Immune Responses of Broilers Following Oral Salmonella typhimurium Inoculation.

    abstract::Manganese (Mn) is an essential nutrient for both host and pathogen. Recent studies have demonstrated the nutritional immunity of Mn against Salmonella infection in mammals. To investigate the effect of high dietary Mn on immune responses of broilers following Salmonella challenge, 144 1-day-old male broilers were fed ...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章


    authors: Pan S,Zhang K,Ding X,Wang J,Peng H,Zeng Q,Xuan Y,Su Z,Wu B,Bai S

    更新日期:2018-02-01 00:00:00

  • Effect of Acetyl-L-Carnitine on Antioxidant Status, Lipid Peroxidation, and Oxidative Damage of Arsenic in Rat.

    abstract::Arsenic (As) is a widespread environmental contaminant present around the world in both organic and inorganic forms. Oxidative stress is postulated as the main mechanism for As-induced toxicity. This study was planned to examine the protective effect of acetyl-L-carnitine (ALC) on As-induced oxidative damage in male r...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Sepand MR,Razavi-Azarkhiavi K,Omidi A,Zirak MR,Sabzevari S,Kazemi AR,Sabzevari O

    更新日期:2016-05-01 00:00:00

  • Inflammatory Factor Alterations in the Gastrointestinal Tract of Cocks Overexposed to Arsenic Trioxide.

    abstract::Exposure of people and animals to arsenic (As) is a global public health concern because As is widely distributed and associated with numerous adverse effects. As is a poisonous metalloid and arsenic trioxide (As2O3) is a form of As. Thus far, there have been very few reports on the inflammatory factor alterations of ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Xing M,Zhao P,Guo G,Guo Y,Zhang K,Tian L,He Y,Chai H,Zhang W

    更新日期:2015-10-01 00:00:00

  • The effect of selenium supplementation in the prevention of DNA damage in white blood cells of hemodialyzed patients: a pilot study.

    abstract::Patients with chronic kidney disease (CKD) have an increased incidence of cancer. It is well known that long periods of hemodialysis (HD) treatment are linked to DNA damage due to oxidative stress. In this study, we examined the effect of selenium (Se) supplementation to CKD patients on HD on the prevention of oxidati...

    journal_title:Biological trace element research

    pub_type: 杂志文章,随机对照试验


    authors: Zachara BA,Gromadzinska J,Palus J,Zbrog Z,Swiech R,Twardowska E,Wasowicz W

    更新日期:2011-09-01 00:00:00

  • Zinc, copper, and zinc- or copper-dependent enzymes in human hypertension.

    abstract::Imbalance of zinc and copper status has been hypothesized in human hypertension. A case-control study was carried out to elucidate the possible relationship between zinc and copper status and essential hypertension. Thirty-one subjects affected by mild stable hypertension, pharmacologically untreated, were investigate...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Vivoli G,Bergomi M,Rovesti S,Pinotti M,Caselgrandi E

    更新日期:1995-08-01 00:00:00

  • The influence of endodontic broken stainless steel instruments on the urinary levels of iron.

    abstract::Previous studies on the endodontic broken stainless steel instruments have mainly focused on retrieval of specimens. However, the systemic consequences of the retained separated instruments need an investigation. The current study aimed to evaluate the correlation between broken stainless steel instruments inside the ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Saghiri MA,Asatourian A,Haraji A,Ramezani GH,Garcia-Godoy F,Scarbecz M,Sheibani N

    更新日期:2014-06-01 00:00:00

  • Effects of taurine on oxidative stress parameters and chromium levels altered by acute hexavalent chromium exposure in mice kidney tissue.

    abstract::The kidney has been regarded as a critical organ of toxicity induced by acute exposure to hexavalent chromium [Cr(VI)] compounds. Reactive intermediates and free radicals generated during reduction process might be responsible for Cr(VI) toxicity. In this study, the effects of pretreatment or posttreatment of taurine ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Boşgelmez II,Güvendik G

    更新日期:2004-01-01 00:00:00

  • Comparison of Thymulin Activity with Other Measures of Marginal Zinc Deficiency.

    abstract::Activity of the immunoregulatory peptide thymulin reflects differences in zinc status. This study compared thymulin activity with four other zinc status measures in rats fed zinc at either 5 or 25 ppm. Rats fed the lower zinc showed the following results compared with rats with adequate zinc intake: serum thymulin act...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: DiSilvestro RA,Dardenne M,Joseph E

    更新日期:2021-02-01 00:00:00

  • Chromium, nickel, and arsenic determinations in human samples by thermal and epithermal neutron activation analyses.

    abstract::Both thermal and epithermal neutron activation analyses have been employed to determine chromium and nickel in lung tissue and arsenic in urine. Based on accuracy, precision, and detection limits, these techniques have been successfully used to analyze lung tissue from a deceased welder, who died, from cancer, and to ...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Landsberger S,Simsons A

    更新日期:1987-08-01 00:00:00

  • Synergistic Effects of Genistein and Zinc on Bone Metabolism and the Femoral Metaphyseal Histomorphology in the Ovariectomized Rats.

    abstract::In this study, we evaluated the synergistic effects of genistein and zinc on bone metabolism, bone mineral density, and the femoral metaphyseal histomorphology in the ovariectomized rats. Sixty female Sprague-Dawley rats, aged 13 weeks, were divided into sham-operated group (SHAM), ovariectomized group (OVX), genistei...

    journal_title:Biological trace element research

    pub_type: 杂志文章


    authors: Qi S

    更新日期:2018-06-01 00:00:00

  • Selenium status, plasma zinc, copper, and magnesium in vegetarians.

    abstract::Plasma zinc (Zn), copper (Cu), and magnesium (Mg) concentrations, copper/zinc ratio, and selenium (Se) status were studied in 44 vegetarians (22 males and 22 females) and their age- and sex-matched nonvegetarians in the Bratislava region (Slovakia). Vegetarians had statistically significant lower levels of plasma Zn a...

    journal_title:Biological trace element research

    pub_type: 临床试验,杂志文章


    authors: Kadrabová J,Madaric A,Kováciková Z,Ginter E

    更新日期:1995-10-01 00:00:00