Abstract:
:The effects of selenium were investigated on three human colon cancer cell lines: Caco 2, HRT 18, and HT 29. At low concentrations (10-100 nM), selenium stimulated cell growth in serum-free medium. Thus, selenium is an essential trace element for cell proliferation. At higher concentrations, selenium inhibited cell growth. The rate of 75Se uptake was the same in all of the cell lines studied, but the quantity incorporated differed. GSH-Px activity was dependent on the selenium content of the medium. DNA and protein synthesis paralleled the growth curve. Comparison with the curve of viability revealed that selenium inhibited cell growth in two ways: by inhibiting DNA synthesis, without affecting cell viability, and, at higher doses, by cytotoxicity.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Nano JL,Czerucka D,Menguy F,Rampal Pdoi
10.1007/BF02919096subject
Has Abstractpub_date
1989-04-01 00:00:00pages
31-43issue
1-2eissn
0163-4984issn
1559-0720journal_volume
20pub_type
杂志文章abstract::Zinc concentrations in the dorsal horn of spinal cord are important for wound healing, neurological function, and reproduction. However, the response of the spinal cord to alterations in dietary zinc is unknown in rats after spinal cord injury (SCI). The current study explored cellular zinc levels and zinc transporter...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-012-9414-9
更新日期:2012-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章,随机对照试验
doi:10.1007/s12011-015-0541-y
更新日期:2016-07-01 00:00:00
abstract::Aspergillus terreus was cultivated on Harrold's medium supplemented with 0.1% (w/v) cadmium chloride as well as on sulfur free medium amended with 0.1% (w/v) sodium selenite and potassium tellurite separately. The cell free extract of the fungus for each treatment was fractionated on a column packed with Sephadex G 75...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02990464
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:103:2:169
更新日期:2005-02-01 00:00:00
abstract::This study aimed to investigate the effects of a combination of a dairy product fermented by lactobacilli (DFL) and galactooligosaccharides (GOS) on mineral balances in growing rats with hypochlorhydria induced by a proton pump inhibitor (PPI). Three-week-old male rats were assigned to receive one of six diets: a cont...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9681-0
更新日期:2013-06-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s12011-017-0949-7
更新日期:2017-09-01 00:00:00
abstract::Plasma molybdenum concentrations were determined in children, ages two to 12 yr, with and without phenylketonuria (PKU). Mean plasma molybdenum concentrations did not differ significantly between the children with PKU (1.33 +/- 0.5 microgram/L) and without PKU (1.75 +/- 0.8 microgram/L). Plasma molybdenum concentratio...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02785307
更新日期:1993-09-01 00:00:00
abstract::Head hair concentrations of zinc, copper, manganese, alid iron from a total of 418 subjects (154 male and 264 female) aged between 6 mo and 20 yr were measured mainly with flameless atomic absorption spectrophotometry. Only zinc analysis of a part of the female samples (n = 140) were analyzed with inductively coupled ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:77:1:43
更新日期:2000-10-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:2002-03-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02820017
更新日期:1998-04-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0512-3
更新日期:2016-05-01 00:00:00
abstract::Aflatoxin B1 (AFB1) is the most toxic among the mycotoxins and causes detrimental health effects on the liver of human and animals. Selenium (Se) plays an important role in protection of various animal species against numerous notorious toxic agents. The present study is designed to explore the protective effects of S...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1623-4
更新日期:2019-10-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-018-1527-3
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abstract::Nonenzymatic glycation of long-lived proteins has been implicated in several complications related to age and diabetes. Dicarbonyl compounds such as methylglyoxal (MGO) have been identified as the predominant source for the formation of advanced glycation end-products (AGEs) in various tissues. We investigated the eff...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8915-7
更新日期:2011-11-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02788959
更新日期:1995-08-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-009-8571-y
更新日期:2010-11-01 00:00:00
abstract::Sediments from 14 stations in the Foshan Waterway, a river crossing the industrial district of Guangdong Province, South China, were sampled and subsequently analyzed. The 14 stations were selected for the pollution discharging features of the river, such as the hydrology, the distribution of pollution sources, and th...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-013-9789-2
更新日期:2013-11-01 00:00:00
abstract::X-ray Fluorescence (XRF) Analysis and Atomic Absorption Spectrophotometry (AAS) have been used in assessing heavy metal pollution from some gold mines in Ghana. The presence and levels of heavy metals in gold ore, gold tailings, inland waters, and river sediments have been determined. Using these techniques, the heavy...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/BF02992682
更新日期:1990-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 临床试验,杂志文章
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journal_title:Biological trace element research
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journal_title:Biological trace element research
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pub_type: 杂志文章
doi:10.1007/s12011-020-02228-2
更新日期:2021-03-01 00:00:00
abstract::Variations of micro- and macrominerals concentration in Swertia speciosa were determined by atomic absorption spectroscopy. The mineral elements showed significant changes in roots and leaves collected from different altitudes. Among all the elements, highest concentration (more than 2,000 mg/kg) of Ca and K were reco...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-010-8611-7
更新日期:2010-12-01 00:00:00
abstract::The toxic mechanism of La3+ to Escherichia coli is investigated by detecting the concentration change of La3+ in E. coli cells growing in La3+-containing medium. Stimulatory action and inhibitory effect of La3+ in different concentrations can be attributed to the permeability alteration of the cell. Low concentration ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/bter:114:1:293
更新日期:2006-01-01 00:00:00
abstract::The kidney has been regarded as a critical organ of toxicity induced by acute exposure to hexavalent chromium [Cr(VI)] compounds. Reactive intermediates and free radicals generated during reduction process might be responsible for Cr(VI) toxicity. In this study, the effects of pretreatment or posttreatment of taurine ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:102:1-3:209
更新日期:2004-01-01 00:00:00
abstract::The objective of this study was to investigate the iron source absorption in the small intestine of broiler. In situ ligated intestinal loops of 70 birds were poured into one of seven solutions, including inorganic iron (FeSO4, Fe2(SO4)3), organic Fe glycine chelate (Fe-Gly(II), Fe-Gly(III)), the mixtures (FeSO4 with ...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-014-0179-1
更新日期:2015-02-01 00:00:00
abstract::In this study, the induction of metallothionein (MT) in one species of oyster Ostrea edulis exposed to copper (Cu) and zinc (Zn) was examined. The quantity of total protein (mg protein/mg dry wt) in each sample and the measurement of MT were determined by the Lowry and silver (Ag)-saturation methods. Our results show ...
journal_title:Biological trace element research
pub_type: 杂志文章
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更新日期:1996-07-01 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-020-02431-1
更新日期:2020-10-15 00:00:00
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journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1385/BTER:113:2:177
更新日期:2006-11-01 00:00:00
abstract::The aim of this study was to investigate the effect of lead (Pb) poisoning on nitric oxide (NO) content, inducible nitric oxide synthase (iNOS) activity, the messenger RNA (mRNA) levels of inflammatory factors (nuclear factor-kappa B (NF-κB), tumor necrosis factor-α (TNF-α), cyclooxygenase-2 (COX-2), prostaglandin E s...
journal_title:Biological trace element research
pub_type: 杂志文章
doi:10.1007/s12011-015-0532-z
更新日期:2016-06-01 00:00:00