Distribution of various nickel compounds in rat organs after oral administration.

Abstract:

:In this study, eight kinds of nickel (Ni) compounds were orally administered to Wistar male rats and the distribution of each compound was investigated 24 h after the administration. The Ni compounds used in this experiment were nickel metal [Ni-M], nickel oxide (green) [NiO(G)], nickel oxide (black) [NiO(B)], nickel subsulfide [Ni3S2], nickel sulfide [NiS], nickel sulfate [NiSO4], nickel chloride [NiCl2], and nickel nitrate [Ni(NO3)2]. The solubilities of the nickel compounds in saline solution were in the following order; [Ni(NO3)2 > NiCl2 > NiSO4] > [NiS > Ni3S2] > [NiO(B) > Ni-M > NiO(G)]. The Ni level in the visceral organs was higher in the rats given soluble Ni compounds; Ni(NO3)2, NiCl2, NiSO4, than that in the rats receiving other compounds. In the rats to which soluble Ni compounds were administered, 80-90% of the recovered Ni amounts in the examined organs was detected in the kidneys. On the other hand, the Ni concentration in organs administered scarcely soluble Ni compounds; NiO(B), NiO(G), and Ni-M were very low. The estimated absorbed fraction of each Ni compounds was increased with the increase of the solubility. These results suggest that the kinetic behavior of Ni compounds administered orally is closely related with the solubility of Ni compounds, and that the solubility of Ni compounds is one of the important factors for determining the health effect of Ni compounds.

journal_name

Biol Trace Elem Res

authors

Ishimatsu S,Kawamoto T,Matsuno K,Kodama Y

doi

10.1007/BF02789001

subject

Has Abstract

pub_date

1995-07-01 00:00:00

pages

43-52

issue

1

eissn

0163-4984

issn

1559-0720

journal_volume

49

pub_type

杂志文章
  • Seasonal variation of metals in seawater, sediment, and Manila clam Ruditapes philippinarum from China.

    abstract::Concentrations of trace metals (Cu, Pb, Zn, Cd, Cr, Hg, and As) were determined for the first time in seawater, sediment, and Manila clam from Deer Island, Liaoning Province, China. The seawater, sediment, and clam samples were collected seasonally at three clam farming sites around Deer Island during 2010-2011. The a...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9628-5

    authors: Zhao L,Yang F,Wang Y,Huo Z,Yan X

    更新日期:2013-06-01 00:00:00

  • Caffeic Acid Protects against Iron-Induced Cardiotoxicity by Suppressing Angiotensin-Converting Enzyme Activity and Modulating Lipid Spectrum, Gluconeogenesis and Nucleotide Hydrolyzing Enzyme Activities.

    abstract::The protective effects of caffeic acid on angiotensin-converting enzyme (ACE) and purinergic enzyme activities, as well as gluconeogenesis was investigated in iron-induced cardiotoxicity. Cardiotoxicity was induced in heart tissues harvested from healthy male SD rats by 0.1 mM FeSO4. Treatment was carried out by co-in...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02227-3

    authors: Salau VF,Erukainure OL,Islam MS

    更新日期:2021-03-01 00:00:00

  • Comparison of metal concentrations in bones of long-living mammals.

    abstract::The aim of this study was to compare zinc, copper, lead, cadmium, and mercury concentrations in the bones of long-living mammals-humans (Homo sapiens) and Canidae (dogs Canis familiaris and foxes Vulpes vulpes) from northwestern Poland and to determine the usefulness of Canidae as bioindicators of environmental exposu...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9615-x

    authors: Lanocha N,Kalisinska E,Kosik-Bogacka DI,Budis H,Sokolowski S,Bohatyrewicz A

    更新日期:2013-05-01 00:00:00

  • Heme and Non-heme Iron on Growth Performances, Blood Parameters, Tissue Mineral Concentration, and Intestinal Morphology of Weanling Pigs.

    abstract::This experiment was conducted to evaluate the effects of heme and non-heme iron sources on growth performances, blood parameters, tissue mineral concentration, and intestinal morphology in weanling pigs. At 25 days of age, 32 newly weaned piglets (Duroc × Landrace × Yorkshire; 8.66 ± 0.59 kg) were allocated to one of ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1385-z

    authors: Zhuo Z,Yu X,Li S,Fang S,Feng J

    更新日期:2019-02-01 00:00:00

  • Positive PCNA and Ki-67 Expression in the Testis Correlates with Spermatogenesis Dysfunction in Fluoride-Treated Rats.

    abstract::The present study aimed to evaluate the effect of fluoride (F) on spermatogenesis in male rats. F- at 50 and 100 mg/L was administered for 70 days, after which the testicular and epididymis tissues were collected to observe the histopathological structure under a light microscope. The ultrastructure of the testis and ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1338-6

    authors: Zhao WP,Wang HW,Liu J,Tan PP,Luo XL,Zhu SQ,Chen XL,Zhou BH

    更新日期:2018-12-01 00:00:00

  • Selenium Prevents Lead-Induced Necroptosis by Restoring Antioxidant Functions and Blocking MAPK/NF-κB Pathway in Chicken Lymphocytes.

    abstract::Recent studies have identified a new existence of a genetically programmed and regulated cell death characterized by necrotic cell death morphology, termed necroptosis. Lead (Pb) is a ubiquitously distributed environmental pollutant that is highly toxic to animals and human beings. However, no detailed report has been...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-020-02094-y

    authors: Zhang J,Hao X,Xu S

    更新日期:2020-12-01 00:00:00

  • Determining human dietary requirements for boron.

    abstract::A dietary requirement is defined as the lowest continuing intake of a nutrient that for a specified indicator of adequacy, will maintain a defined level of nutriture in an individual. An essential dietary component is one that the body cannot synthesize in sufficient quantities to maintain health. Recommended dietary ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783138

    authors: Sutherland B,Strong P,King JC

    更新日期:1998-01-01 00:00:00

  • Neuroprotective Effect of Portulaca oleraceae Ethanolic Extract Ameliorates Methylmercury Induced Cognitive Dysfunction and Oxidative Stress in Cerebellum and Cortex of Rat Brain.

    abstract::Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0546-6

    authors: Sumathi T,Christinal J

    更新日期:2016-07-01 00:00:00

  • Serum protein and zinc levels in patients with thoracic empyema.

    abstract::The element Zn is the metal component or activator of many important enzymes. The tissue concentrations and activities of Zn metalloenzymes direct the rate of protein and nucleic acid syntheses, thereby influencing tissue growth and reperative processes. Most of the serum Zn is normally bound to circulating proteins. ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02786257

    authors: Balkan ME,Ozgüneş H

    更新日期:1996-08-01 00:00:00

  • The effects of dietary supplementation with chromium picolinate throughout gestation on productive performance, Cr concentration, serum parameters, and colostrum composition in sows.

    abstract::The objective of this study was to determine the effects of supplemental chromium as chromium picolinate (CrPic) on productive performance, chromium (Cr) concentration, serum parameters, and colostrum composition in sows. Thirty Yorkshire sows were bred with semen from a pool of Landrace boars. The sows were equally g...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9699-3

    authors: Wang L,Shi Z,Jia Z,Su B,Shi B,Shan A

    更新日期:2013-07-01 00:00:00

  • Dietary boron supplementation enhanced the action of estrogen, but not that of parathyroid hormone, to improve trabecular bone quality in ovariectomized rats.

    abstract::This study investigated whether boron would enhance the ability of 17beta-estradiol (E2) or parathyroid hormone (PTH) to improve bone quality in ovariectomized OVX rats. Adult OVX rats were treated for 5 wk with vehicle, boron (5 ppm as boric acid), E2 (30 microg/kg/d, sc), PTH (60 microg/kg/d, sc), or a combination o...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/bter:82:1-3:109

    authors: Sheng MH,Taper LJ,Veit H,Qian H,Ritchey SJ,Lau KH

    更新日期:2001-07-01 00:00:00

  • Dose- and time-dependent effects of luteolin on liver metallothioneins and metals in carbon tetrachloride-induced hepatotoxicity in mice.

    abstract::The aim of this study was to investigate the protective effect of luteolin on liver Ca, Mg, Zn, Cu, Fe, and Mn content in mice with carbon tetrachloride (CCl4)-induced hepatotoxicity. Additionally, liver metallothionein (MT) expression was studied. Luteolin was administered intraperitoneally (i.p.) as a single 5- or 5...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-008-8181-0

    authors: Domitrović R,Jakovac H,Grebić D,Milin C,Radosević-Stasić B

    更新日期:2008-01-01 00:00:00

  • Trace elements in different brands of yerba mate tea.

    abstract::Yerba mate (Ilex paraguariensis), a widely consumed beverage in South America, contains various biochemically active substances, among them are several minerals. This paper reports on the results of a survey of trace elements in the yerba mate infusions. Three different commercially available trademarks of I. paraguar...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-011-9056-3

    authors: Bragança VL,Melnikov P,Zanoni LZ

    更新日期:2011-12-01 00:00:00

  • Effects of La3+ on the competence of Escherichia coli as studied by microcalorimetry.

    abstract::A series of microcalorimetric experiments were performed to investigate the effect of La(3+) on the formation of the competent state of Escherichia coli HB101 by using a LKB-2277 BioActivity Monitor at 37 C. The thermogenic curves in the absence and in the presence of La(3+) were obtained. Based on these curves, we ca...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/bter:91:3:267

    authors: Wenhua L,Yi L,Ruming Z,Zhixiong X,Ping S,Songsheng Q

    更新日期:2003-03-01 00:00:00

  • Toxicity of Copper Oxide (CuO) Nanoparticles on Human Blood Lymphocytes.

    abstract::CuO nanoparticles (CuO-NPs) serve several important functions in human life, particularly in the fields of medicine, engineering, and technology. These nanoparticles have been utilized as catalysts, semiconductors, sensors, gaseous and solid ceramic pigments, and magnet rotatable devices. Further use for CuO-NPs has b...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-017-1170-4

    authors: Assadian E,Zarei MH,Gilani AG,Farshin M,Degampanah H,Pourahmad J

    更新日期:2018-08-01 00:00:00

  • Heavy Metals in Indigenous Preparations Used for Sex Selection During Pregnancy in India.

    abstract::Indigenous preparations (IPs) have evoked a considerable interest in alleviating infections and chronic diseases and improving wellbeing. While such formulations have been a part of traditional practice in several countries and many have been reviewed scientifically for their claims, several of them until date remain ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-018-1411-1

    authors: Ganguli A,Rai P,Balachandran S,Gupta R,Sharma R,Neogi SB

    更新日期:2019-04-01 00:00:00

  • Influence of the coat color on the trace elemental status measured by particle-induced X-ray emission in horse hair.

    abstract::The influence of hair color on the trace elemental status in horse's hair has been studied. A current analytical technique such as particle-induced X-ray emission (PIXE) used in this study has provided reliable, rapid, easy, and relatively inexpensive diagnostic methods. Twenty-eight elements (Al, Br, Ca, Cl, Co, Cu, ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:103:2:169

    authors: Asano K,Suzuki K,Chiba M,Sera K,Matsumoto T,Asano R,Sakai T

    更新日期:2005-02-01 00:00:00

  • Comparison of clastogenic effects of antimony and bismuth as trioxides on mice in vivo.

    abstract::Comparison of the clastogenic effects of antimony and bismuth used as trioxides, when administered orally by gavaging to laboratory bred male mice, showed that the former was more strongly clastogenic than the latter. Three doses of each chemical (400, 666.67, and 1000 mg/kg body wt), corresponding to 1/50, 1/30, and ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02783802

    authors: Gurnani N,Sharma A,Talukder G

    更新日期:1993-05-01 00:00:00

  • Modulation of testicular and whole blood trace element concentrations in conjunction with testosterone release following kisspeptin administration in male rabbits (Oryctolagus cuniculus).

    abstract::The present study investigated the role of kisspeptin-10 on reproductively significant trace elements in relation to testosterone release in male rabbits, Oryctolagus cuniculus. Groups of rabbits were exposed to single 1 μg kisspeptin dose (i.v., saphenous vein), while simultaneous groups were pretreated with a kisspe...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-013-9720-x

    authors: Qureshi IZ,Abbas Q

    更新日期:2013-08-01 00:00:00

  • Synergistic toxicity between arsenic and methylated selenium compounds.

    abstract::Arsenite has been known for half a century to have a protective effect against selenium poisoning. Paradoxically, arsenite inhibits the conversion of inorganic selenium salts to methylated excretory products, although methylation has long been regarded as a detoxification mechanism for selenium. Moreover, there is evi...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02919103

    authors: Kraus RJ,Ganther HE

    更新日期:1989-04-01 00:00:00

  • Comparison of selenium levels in pre-eclamptic and normal pregnancies.

    abstract::Abnormal placentation is the likely cause of the slow fetal growth and the high levels of circulating lipid peroxides found in severe pre-eclampsia. These peroxides are probably responsible for the high thromboxane:prostacyclin ratio found in this disease and may participate in the endothelial cell damage which is its...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784164

    authors: Rayman MP,Abou-Shakra FR,Ward NI,Redman CW

    更新日期:1996-10-01 00:00:00

  • Combined effects of muscular dystrophy, ecological stress, and selenium on blood antioxidant status in broiler chickens.

    abstract::The results obtained in this study demonstrated that experimentally induced alimentary muscular dystrophy (MD) in Cobb 500 broiler chickens resulted in increased plasma concentrations of malondialdehyde (MDA), deviations in activities of erythrocyte antioxidant enzymes Cu,Zn-SOD (decrease), and CAT (increase) as well ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-010-8782-2

    authors: Georgieva NV,Stoyanchev K,Bozakova N,Jotova I

    更新日期:2011-09-01 00:00:00

  • Trace elements found to be variable in two coral reef species, Heliofungia actiniformis and Galaxea fascicularis, collected from the Ryukyu Islands.

    abstract::Biominerals and metals of intertidal corals of two species (Heliofungia actiniformis, Quoy and Gaimard; Galaxea fascicularis, Linnaeus), collected from the Iriomote Island of Ryukyu, were examined with an inductively coupled plasma atomic emission spectrometer (ICP-AES). Twelve elements were detectable in the corallin...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/BF02784268

    authors: Yamada G,Fujimori K,Yamada M,Minami T,Tohno S,Tohno Y

    更新日期:1998-11-01 00:00:00

  • Sodium selenate partially corrects impaired functional responses in detrusor muscle in streptozotocin-induced diabetic rats.

    abstract::Selenium selenate was administered to streptozotocin-induced diabetic rats to assess its effects on the detrusor muscle. Thirty-two rats were divided into four groups of eight subjects each. The study animals were made diabetic by means of a single intravenous injection of streptozotocin (STZ). The responsiveness of t...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:93:1-3:171

    authors: Gür S,Cinel I

    更新日期:2003-07-01 00:00:00

  • Enrichment, Distribution of Vanadium-Containing Protein in Vanadium-Enriched Sea Cucumber Apostichopus japonicus and the Ameliorative Effect on Insulin Resistance.

    abstract::Sea cucumbers are a potential source of natural organic vanadium that may improve insulin resistance. In this work, vanadium was accumulated rapidly in blood, body wall, and intestine by sea cucumber Apostichopus japonicus. Furthermore, water-soluble vanadium-containing proteins, the main form of the organic vanadium,...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-015-0517-y

    authors: Liu Y,Zhou Q,Zhao Y,Wang Y,Wang Y,Wang J,Xu J,Xue C

    更新日期:2016-05-01 00:00:00

  • Promotion of lipid oxidation by selenate and selenite and indicators of lipid peroxidation in the rat.

    abstract::The AIN-93 reformulation of the AIN-76A rodent diet includes a change in selenium supplement from sodium selenite to sodium selenate to reduce dietary lipid peroxidation. A change to selenate as the standard form of Se in rat diets would render results from previous work using selenite less relevant for comparison wit...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:79:3:257

    authors: Moak MA,Christensen MJ

    更新日期:2001-03-01 00:00:00

  • Retraction note to: The effect of lead acetate toxicity on experimental male albino rat.

    abstract::Retraction to: Biol Trace Elem Res 144(1–3):1120–1132, DOI 10.1007/s12011-011-9149-z. Article has been retracted due to duplicate publication. ...

    journal_title:Biological trace element research

    pub_type: 撤回出版物

    doi:10.1007/s12011-012-9550-2

    authors: Ibrahim NM,Eweis EA,El-Beltagi HS,Abdel-Mobdy YE

    更新日期:2013-01-01 00:00:00

  • Evaluation of allicin for the treatment of experimentally induced subacute lead poisoning in sheep.

    abstract::Garlic (Allium sativum) is known to reduce lead toxicity in some species of animals. The objective of this study was to evaluate the efficacy of allicin, one of the most active components of garlic, in the treatment of subacute lead intoxication in sheep. Nine female sheep weighing 25-29 kg orally received a daily dos...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1007/s12011-008-8185-9

    authors: Najar-Nezhad V,Aslani MR,Balali-Mood M

    更新日期:2008-01-01 00:00:00

  • Magnesium Supplementation and the Effects on Wound Healing and Metabolic Status in Patients with Diabetic Foot Ulcer: a Randomized, Double-Blind, Placebo-Controlled Trial.

    abstract::Hypomagnesemia is associated with the development of neuropathy and abnormal platelet activity, both of which are risk factors for diabetic foot ulcer (DFU). This study was carried out to evaluate the effects of magnesium administration on wound healing and metabolic status in subjects with DFU. This randomized, doubl...

    journal_title:Biological trace element research

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s12011-017-1056-5

    authors: Razzaghi R,Pidar F,Momen-Heravi M,Bahmani F,Akbari H,Asemi Z

    更新日期:2018-02-01 00:00:00

  • Effects of statins on oxidative stress.

    abstract::Free oxygen radicals and insufficient antioxidant enzymes have been implicated in the pathogenesis of hypercholesterolemia (HC). Trace elements function as cofactors in antioxidant enzymes. Antioxidant system and trace elements were investigated in many different studies including HC, but these subjects have not been ...

    journal_title:Biological trace element research

    pub_type: 杂志文章

    doi:10.1385/BTER:98:2:119

    authors: Yilmaz MI,Baykal Y,Kilic M,Sonmez A,Bulucu F,Aydin A,Sayal A,Kocar IH

    更新日期:2004-05-01 00:00:00