Structural studies of the SET domain from RIZ1 tumor suppressor.

abstract：:Chronic kidney disease (CKD) has recently emerged as a major risk factor for cardiovascular pathology. CKD patients display accelerated atherosclerotic process, leading to circulatory complications. However, it is currently not clear how uremic conditions accelerate atherosclerosis. Apoptosis is an important homeostat...

journal_title：Biochemical and biophysical research communications

authors： Trécherel E,Godin C,Louandre C,Benchitrit J,Poirot S,Mazière JC,Massy ZA,Galmiche A

更新日期：2012-01-06 00:00:00

abstract：:Although oxygen levels in the extracellular space of most mammalian tissues are just a few percent, under standard cell culture conditions they are not regulated and are often substantially higher. Some cellular sources of reactive oxygen species, like NADPH oxidase 4, are sensitive to oxygen levels in the range betwe...

journal_title：Biochemical and biophysical research communications

authors： Maddalena LA,Selim SM,Fonseca J,Messner H,McGowan S,Stuart JA

更新日期：2017-11-04 00:00:00

abstract：:Pulse labeling followed by SDS-PAGE electrophoresis of immunoprecipitated [35S]methionine-labeled steroid sulfatase (STS) gave a single band of molecular weight 65,000 daltons. After a chase period of 18 hours the material appeared as molecular weight approximately 64,000. No labeled STS could be detected in fibroblas...

journal_title：Biochemical and biophysical research communications

authors： Horwitz AL,Warshawsky L,King J,Burns G

更新日期：1986-03-13 00:00:00

abstract：:Engineered adipose tissue could be used for the reconstruction or augmentation of soft tissues lost due to mastectomy or lumpectomy in plastic and reconstructive surgery. Preadipocytes are a feasible cell source for adipose tissue regeneration. However, the enhancement of the in vivo adipogenic conversion of preadipoc...

journal_title：Biochemical and biophysical research communications

authors： Cho SW,Kim I,Kim SH,Rhie JW,Choi CY,Kim BS

更新日期：2006-06-30 00:00:00

abstract：:Adenosine inhibits ram sperm adenylate cyclase activity which is membrane-bound and comprises only the catalytic subunit. The inhibition parameters of adenylate cyclase by adenosine were not modified when the enzyme was purified 3 to 5,000 fold. Optimal inhibition by adenosine was found to require a high concentration...

journal_title：Biochemical and biophysical research communications

authors： Henry D,Ferino F,Tomova S,Ferry N,Stengel D,Hanoune J

更新日期：1986-06-30 00:00:00

abstract：:Reaction of metmyoglobin with peroxides is known to involve the formation, possibly via a porphyrin radical-cation, of a ferryl (iron(IV)-oxo) species and a protein radical; there is a little information available as to which of these species initiates the damage which is observed on incubating membrane fractions with...

journal_title：Biochemical and biophysical research communications

authors： Newman ES,Rice-Evans CA,Davies MJ

更新日期：1991-09-30 00:00:00

abstract：:DNA mismatch repair (MMR) is critical for the maintenance of genomic stability. MMR is initiated by recognition of DNA mismatches by the protein, MutS, which subsequently recruits downstream repair factors. To better understand the mechanism by which MutS identifies and specifically binds mismatched basepairs embedded...

journal_title：Biochemical and biophysical research communications

authors： Jia Y,Bi L,Li F,Chen Y,Zhang C,Zhang X

更新日期：2008-08-08 00:00:00

abstract：:The effect of the mitochondrial dye rhodamine 123 (Rho 123) on protein synthesis (PS) activity was investigated in mitochondria isolated from liver and from both chloroma and erythroleukemia tumors. Incorporation of labelled leucine into mitochondrial protein was used to measure the rate of PS. While PS specific activ...

journal_title：Biochemical and biophysical research communications

authors： Abou-Khalil WH,Arimura GK,Yunis AA,Abou-Khalil S

更新日期：1986-06-13 00:00:00

abstract：:Arrestins have important roles in G protein-coupled receptor (GPCR) signaling including desensitization of GPCRs and G protein-independent signaling. There have been four arrestins identified: arrestin1, arrestin2 (e.g. β-arrestin1), arrestin3 (e.g. β-arrestin2), and arrestin4. β-Arrestin1 and β-arrestin2 are ubiquito...

journal_title：Biochemical and biophysical research communications

authors： Yun Y,Kim DK,Seo MD,Kim KM,Chung KY

更新日期：2015-01-30 00:00:00

abstract：:Previous reports have shown that CaM-kinase IV can phosphorylate the transcription factor CREB in vitro on Ser133. Furthermore, transfected CaM-kinase IV can activate CREB-dependent transcription, but at a lower efficiency than the cAMP-kinase. In this paper we examine the kinetics and site-specificity of CREB phospho...

journal_title：Biochemical and biophysical research communications

authors： Enslen H,Tokumitsu H,Soderling TR

更新日期：1995-02-27 00:00:00

abstract：:The modification of chromatin structure is increasingly recognized to be an important facet of transcriptional regulation. Here, we report that Brahma-related gene 1 (BRG1), a chromatin remodeling enzyme, plays a crucial role in IFN-γ-induced TRIM22 expression. Our results showed that IFN-γ failed to induce TRIM22 exp...

journal_title：Biochemical and biophysical research communications

authors： Wang Y,Gao B,Xu W,Xiong S

更新日期：2011-07-08 00:00:00

abstract：:Epidemiological and experimental data suggest a role for polyunsaturated fatty acids in the etiology of breast cancer. In this report we have studied arachidonic acid and linoleic acid metabolism in the human breast carcinoma cell line BT-20 which overexpresses both EGF receptor and the homologous erbB-2 oncogene prod...

journal_title：Biochemical and biophysical research communications

authors： Reddy N,Everhart A,Eling T,Glasgow W

更新日期：1997-02-03 00:00:00

abstract：:Lariciresinol is an enterolignan precursor isolated from the herb Sambucus williamsii, a folk medicinal plant used for its therapeutic properties. In this study, the antifungal properties and mode of action of lariciresinol were investigated. Lariciresinol displays potent antifungal properties against several human pa...

journal_title：Biochemical and biophysical research communications

authors： Hwang B,Cho J,Hwang IS,Jin HG,Woo ER,Lee DG

更新日期：2011-07-08 00:00:00

abstract：:The human leukemia cell line KU812 had been described as an immature prebasophilic cell line and exhibits a potential to differentiate into mature basophils. We studied the effect of interleukin-4 (IL-4) on the basophilic differentiation of KU812 cells. When KU812 cells were cultured with 1 ng/ml IL-4, cellular histam...

journal_title：Biochemical and biophysical research communications

authors： Hara T,Yamada K,Tachibana H

更新日期：1998-06-29 00:00:00

abstract：:Methanococcus voltae produces two flagellins of molecular weight 31,000 and 33,000. Amino acid analysis as well as peptide mapping with cyanogen bromide, chymotrypsin and Staphylococcus aureus V-8 protease indicates that the two flagellins are distinct. N-terminal sequencing of the 31,000 Mc. voltae flagellin as well ...

journal_title：Biochemical and biophysical research communications

authors： Kalmokoff ML,Karnauchow TM,Jarrell KF

更新日期：1990-02-28 00:00:00

abstract：:Recombination in a bovine papillomavirus shuttle vector carrying direct repeats of Moloney murine leukemia virus LTR sequence was examined. Differently from similar vectors carrying direct repeats of SV40 polyA addition signal or neomycin resistance gene, the vector exhibited no homologous recombination between the re...

journal_title：Biochemical and biophysical research communications

authors： Kitamura Y,Naito A,Yoshikura H

更新日期：1991-08-30 00:00:00

abstract：:The spectrum of resting cytochrome c oxidase is modulated by valinomycin addition, which induces a red shift of the Soret band. The enzyme is known both to fluoresce and phosphorescence, effects which can be modulated by certain protein reagents and quenchers. Valinomycin had little effect upon fluorescence at 335 nm,...

journal_title：Biochemical and biophysical research communications

authors： Butko P,He J,Nicholls P

更新日期：1992-12-30 00:00:00

abstract：:The recognition and removal of interstrand cross-links is perhaps the least understood of all repair pathways in eukaryotic cells. We have shown previously that uncoupling of cross-links occurs in mammalian cell extracts and have identified a number of factors that mediate this process. However, we have not observed c...

journal_title：Biochemical and biophysical research communications

authors： Lu X,Zhang N,Vasquez K,Barton M,Legerski R

更新日期：2005-10-14 00:00:00

abstract：:TonEBP/NFAT5 transcription factor is a master regulator of genes involved in osmoprotection. Cyclooxygenase 2 (COX2) has been reported to be a cytoprotective molecule in the inner renal medulla, where cells are physiologically exposed to the highest osmolality of the body. Our aim was to study whether COX2 expression ...

journal_title：Biochemical and biophysical research communications

authors： Favale NO,Casali CI,Lepera LG,Pescio LG,Fernández-Tome MC

更新日期：2009-04-10 00:00:00

abstract：:Human monomorphic and polymorphic arylamine acetyltransferases (EC 2.3.1.5) were expressed in monkey kidney COS-1 cells and used to study the N- and O-acetylation of a number of carcinogenic amines and their N-hydroxy metabolites. The monomorphic enzyme N-acetylated the aromatic amines, 2-aminofluorene and 4-aminobiph...

journal_title：Biochemical and biophysical research communications

authors： Minchin RF,Reeves PT,Teitel CH,McManus ME,Mojarrabi B,Ilett KF,Kadlubar FF

更新日期：1992-06-30 00:00:00

abstract：:Peroxisomes catalyze a number of essential metabolic functions especially related to lipid metabolism. There is increasing evidence suggesting that peroxisomes are also involved in the synthesis of isoprenoids via the mevalonate pathway at least in rat liver. In order to obtain independent evidence for a role of perox...

journal_title：Biochemical and biophysical research communications

authors： Wanders RJ,Romeijn GJ

更新日期：1998-06-29 00:00:00

abstract：:MET, also known as hepatocyte growth factor receptor (HGFR), is a receptor tyrosine kinase with an important role, both in normal cellular function as well as in oncogenesis. In many cancer types, abnormal activation of MET is related to poor prognosis and various strategies to inhibit its function, including small mo...

journal_title：Biochemical and biophysical research communications

authors： Humbert M,Medová M,Aebersold DM,Blaukat A,Bladt F,Fey MF,Zimmer Y,Tschan MP

更新日期：2013-02-08 00:00:00

abstract：:Peptides with a molecular weight of 5 kDa have been isolated from seeds of the pinto bean and red bean, respectively. The peptides manifest an N-terminal sequence with remarkable resemblance to those of cowpea 10-kDa protein precursor and garden pea disease resistance response protein. The bean peptides possess potent...

journal_title：Biochemical and biophysical research communications

authors： Ye XY,Ng TB

更新日期：2001-07-13 00:00:00

abstract：:The activity of the enzyme tyrosine aminotransferase and the synthesis of its specific mRNA were evaluated at different hours of the day in the liver of 3-, 12- and 24-month old BN rats. The enzyme activity has a circadian rhythm with a peak at midnight in 3- and 12-month old, which shifts to 03.00 hrs in 24-month old...

journal_title：Biochemical and biophysical research communications

authors： Servillo G,Della Fazia MA,Viola-Magni M

更新日期：1991-02-28 00:00:00

abstract：:The addition of low concentrations of phorbol 12-myristate 13-acetate to rabbit neutrophils induces cell aggregation, degranulation, increased oxygen consumption and an increase in the amount of actin associated with the cytoskeleton without a rise in the level of intracellular free calcium as measured using the fluor...

journal_title：Biochemical and biophysical research communications

authors： Sha'afi RI,White JR,Molski TF,Shefcyk J,Volpi M,Naccache PH,Feinstein MB

更新日期：1983-07-29 00:00:00

abstract：:The transcription factor sterol regulatory element-binding protein 1c (SREBP1c) plays an important role in the control of fatty acid metabolism in the liver. Evidence suggests that mammalian target of rapamycin (mTOR) complex 1 (mTORC1) contributes to the regulation of SREBP1c expression, but signaling downstream of m...

journal_title：Biochemical and biophysical research communications

authors： Li S,Ogawa W,Emi A,Hayashi K,Senga Y,Nomura K,Hara K,Yu D,Kasuga M

更新日期：2011-08-26 00:00:00

abstract：:Chondromodulin-I (ChM-I) is a cartilage-specific glycoprotein that stimulates the growth of chondrocytes and inhibits the tube formation of endothelial cells. In the present study, we identified a novel ChM-I like molecule, designated ChM1L. Cloning of full length cDNAs of human, mouse, and rat ChM1L revealed that ChM...

journal_title：Biochemical and biophysical research communications

authors： Yamana K,Wada H,Takahashi Y,Sato H,Kasahara Y,Kiyoki M

更新日期：2001-02-02 00:00:00

abstract：:In this report, we demonstrate that HL-60 nuclei isolated in calcium but not EGTA containing buffers specifically bind PE and express approximately 37,000 receptor sites/nucleus. Nuclear phorbol ester binding is lost by isolation in the absence of calcium, but can be repleted by the addition of partially purified prot...

journal_title：Biochemical and biophysical research communications

authors： Kraft AS,Appling C,Berkow RL

更新日期：1987-04-14 00:00:00

abstract：:Circulating hormones are engaged in initiating and controlling the process of spermatogenesis, however, the Sertoli cell tight junctions prevent these substances from directly influencing the spermatogenic cells. Thus, the Sertoli cells play a vital role in regulating the spermatogenic process. Our studies correlate r...

journal_title：Biochemical and biophysical research communications

authors： Page KC,Heitzman DA,Chernin MI

更新日期：1996-05-15 00:00:00

abstract：:Although brain natriuretic peptide (BNP) is a novel natriuretic peptide originally identified in porcine brain, recent investigation has verified the presence of BNP in porcine heart. In order to identify BNP as a circulating hormone, we analyzed the regional distribution and molecular form of immunoreactive (ir-) BNP...

journal_title：Biochemical and biophysical research communications

authors： Aburaya M,Minamino N,Kangawa K,Tanaka K,Matsuo H

更新日期：1989-12-15 00:00:00