Infection in the elderly.

abstract：:Tyrosine kinase inhibitors represent the standard of care for several diseases and drug targets in hematologic malignancies. Infectious complications vary by disease status and prior therapy, but overall incidence of infections generally is low. In chronic diseases, such as chronic myeloid leukemia and chronic lymphoc...

journal_title：Infectious disease clinics of North America

authors： Kin A,Schiffer CA

更新日期：2020-06-01 00:00:00

abstract：:Throughout history, infectious diarrhea has been associated with crowding, poor sanitation, and war. Although descriptions of infectious diarrhea exist in the earliest records of civilization, effective measures for prevention were not widely or consistently used until the modern era of active public health promotion....

journal_title：Infectious disease clinics of North America

authors： Lim ML,Wallace MR

更新日期：2004-06-01 00:00:00

abstract：:This article addresses current issues regarding serologic testing for selected STDs, particularly those for which serologic testing has been useful for diagnosis, monitoring therapy, or seroepidemiology. For each selected pathogen, the authors discuss the strengths and weaknesses of the serologic tests as diagnostic a...

journal_title：Infectious disease clinics of North America

authors： Thomas DL,Quinn TC

更新日期：1993-12-01 00:00:00

abstract：:This article reviews the changing epidemiology of infections associated with injection drug use, perceived barriers to care, features of successful programs for outpatient antimicrobial treatment, models of shared decision making at the time of discharge, and linkage to preventative care after antimicrobial completion...

journal_title：Infectious disease clinics of North America

authors： Hurley H,Sikka M,Jenkins T,Cari EV,Thornton A

更新日期：2020-09-01 00:00:00

abstract：:Antimicrobial resistance is a natural evolutionary process, which in the case of Mycobacterium tuberculosis is based on spontaneous chromosomal mutations, meaning that well-designed combination drug regimens provided under supervised therapy will prevent the emergence of drug-resistant strains. Unfortunately, limited ...

journal_title：Infectious disease clinics of North America

authors： Kurz SG,Furin JJ,Bark CM

更新日期：2016-06-01 00:00:00

abstract：:At the close of the 19th century, the germ theory had generated a new understanding of the causes of acute infectious diseases and revealed new directions for study. This understanding contributed to the greatest improvements in health in the history of medicine. At the end of the 20th century, the second stage of thi...

journal_title：Infectious disease clinics of North America

authors： Ewald PW

更新日期：2004-03-01 00:00:00

abstract：:Staphylococcus aureus is a leading cause of bacteremia and endocarditis. Over the past several years, the frequency of S. aureus bacteremia (SAB) has increased dramatically. This increasing frequency, coupled with increasing rates of antibiotic resistance, has renewed interest in this serious, common infection. S. aur...

journal_title：Infectious disease clinics of North America

authors： Petti CA,Fowler VG Jr

更新日期：2002-06-01 00:00:00

abstract：:As the result of a formidable effort, the recent TB epidemic in the United States has abated; however, major questions remain as the risk of TB diminishes. Will we maintain an adequate public health effort not only to prevent another resurgence of TB but also to renew our pursuit of TB elimination? Do we have the will...

journal_title：Infectious disease clinics of North America

authors： Griffith DE

更新日期：1998-09-01 00:00:00

abstract：:Cytomegaloviruses (CMVs) are DNA viruses and are members of the Herpesviridae family. Morphologically, CMV resembles other herpes viruses, particularly herpes simplex viruses, with important cytopathic differences. CMVs are recognized pathogens that cause community-acquired pneumonia (CAP) in compromised hosts, such a...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2010-03-01 00:00:00

abstract：:Although antibiotic therapy is the mainstay of therapy for gram-negative bacillary bacteremia, the amelioration of the underlying conditions, the correction of predisposing factors, the drainage of abscesses, the removal of infected foreign bodies, and adequate supportive care are also of paramount importance for curi...

journal_title：Infectious disease clinics of North America

authors： Calandra T,Cometta A

更新日期：1991-12-01 00:00:00

abstract：:In this article, gynecologic conditions of increased importance in the HIV-infected woman are discussed. Women living with HIV may have an increase in menstrual disorders, lower genital tract neoplasias, gynecologic surgery, and sexually transmitted infections. The literature relevant to choosing a method of contracep...

journal_title：Infectious disease clinics of North America

authors： Cejtin HE

更新日期：2008-12-01 00:00:00

abstract：:The diagnostic approach to the compromised host with CNS infection depends on an analysis of the patient's clinical manifestations of CNS disease, the acuteness or subacuteness of the clinical presentation, and an analysis of the type of immune defect compromising the patient's host defenses. Most patients with CNS in...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:Diarrhea is one of the most common causes of morbidity and mortality in children worldwide. The causes of acute diarrhea in children vary with the location, time of year, and population studied. There is increasing recognition of a widening array of enteric pathogens associated with diarrheal diseases. Adequate fluid ...

journal_title：Infectious disease clinics of North America

authors： Dennehy PH

更新日期：2005-09-01 00:00:00

abstract：:The identification of characteristic clinical, serologic, and immunologic responses to primary HIV infection has contributed greatly to our understanding of the natural history of HIV infection. Subjects usually present with a mononucleosis-like illness and during the period of primary infection there is a characteris...

journal_title：Infectious disease clinics of North America

authors： Tindall B,Cooper DA,Donovan B,Penny R

更新日期：1988-06-01 00:00:00

abstract：:Vancomycin and daptomycin are options for the initial treatment of patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Treatment options for persistent MRSA bacteremia or bacteremia due to vancomycin-intermediate or vancomycin-resistant strains include daptomycin, ceftaroline, and combination ...

journal_title：Infectious disease clinics of North America

authors： Holubar M,Meng L,Alegria W,Deresinski S

更新日期：2020-12-01 00:00:00

abstract：:Global eradication of smallpox, elimination of poliomyelitis in the Western Hemisphere, and a 90% decrease in Haemophilus influenzae meningitis in the Western Hemisphere mark some of the achievements of immunization programs around the world. Yet many serious problems continue to exist, particularly in the developing ...

journal_title：Infectious disease clinics of North America

authors： Grossman M

更新日期：1995-06-01 00:00:00

abstract：:This article provides background information on the pharmacokinetics of antibacterial agents in patients who have normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. The use of serum levels; newer strategies for cefazolin, va...

journal_title：Infectious disease clinics of North America

authors： Gilbert B,Robbins P,Livornese LL Jr

更新日期：2009-12-01 00:00:00

abstract：:Antimicrobial stewardship programs aim to monitor, improve, and measure responsible antibiotic use. The intensive care unit (ICU), with its critically ill patients and prevalence of multiple drug-resistant pathogens, presents unique challenges. This article reviews approaches to stewardship with application to the ICU...

journal_title：Infectious disease clinics of North America

authors： Doernberg SB,Chambers HF

更新日期：2017-09-01 00:00:00

abstract：:Acquired immunodeficiency syndrome (AIDS) is the lethal end stage of a sexually transmitted disease caused by a virus that is producing the major epidemic of our century. In this article we describe the history and epidemiology of AIDS and the disease states associated with infection with the human immunodeficiency vi...

journal_title：Infectious disease clinics of North America

authors： Wood RW,Collier A

更新日期：1987-03-01 00:00:00

abstract：:The central nervous system and systemic complications of bacterial meningitis cause significant morbidity and mortality. This article offers insight into the clinical features, pathogenesis, and management of these complications. In many instances, the improved outcome of intervention is based on clinical suspicion an...

journal_title：Infectious disease clinics of North America

authors： Rauf SJ,Roberts NJ Jr

更新日期：1999-09-01 00:00:00

abstract：:This article establishes the pharmacokinetic-pharmacodynamic parameters that are important when considering the intracellular activity of antibiotics. Generally speaking, the main classes of antibiotics seem to share globally the same properties against extracellular and intracellular organisms. The specific cellular ...

journal_title：Infectious disease clinics of North America

authors： Carryn S,Chanteux H,Seral C,Mingeot-Leclercq MP,Van Bambeke F,Tulkens PM

更新日期：2003-09-01 00:00:00

abstract：:Fulminant meningitis requires aggressive management in an intensive care unit setting. The pathophysiology of the various factors that damage the central nervous system in this disease have been reviewed, as well as the management of the many complications of this serious, often devastating, infection. The etiologic a...

journal_title：Infectious disease clinics of North America

authors： Roos KL,Scheld WM

更新日期：1989-03-01 00:00:00

abstract：:Renal transplant recipients continue to have progressive kidney dysfunction and renal graft loss has been attributed to emerging opportunistic infections, specifically BK virus (BKV). BKV is postulated to be selected by the new potent immunosuppressive medications and to be an important factor in graft failure. The pr...

journal_title：Infectious disease clinics of North America

authors： Balba GP,Javaid B,Timpone JG Jr

更新日期：2013-06-01 00:00:00

abstract：:Critical-care units can be barometers for appropriate antimicrobial use. There, life and death hang on empirical antimicrobial therapy for treatment of infectious diseases. With increasing therapeutic empiricism, triple-drug, broad-spectrum regimens are often necessary, but cannot be continued without fear of the doub...

journal_title：Infectious disease clinics of North America

authors： Owens RC Jr

更新日期：2009-09-01 00:00:00

abstract：:Occupational transmission of hepatitis B virus (HBV), hepatitis C virus, and HIV has been documented. The risk for occupationally transmitted infection varies for these three viruses. Despite effective pre- and postexposure prophylaxis for HBV and recent recommendations for postexposure chemoprophylaxis after an HIV e...

journal_title：Infectious disease clinics of North America

authors： Cardo DM,Bell DM

更新日期：1997-06-01 00:00:00

abstract：:Genome-wide association studies have identified polymorphisms located near the gene encoding IL28B, which turned out to be the best predictor of response to pegylated interferon plus ribavirin for chronic hepatitis C virus (HCV) genotype 1 infection. This association was extended to spontaneous clearance of HCV, sugge...

journal_title：Infectious disease clinics of North America

authors： Berger CT,Kim AY

更新日期：2012-12-01 00:00:00

abstract：:We have proposed a model in which the initiation of human parturition in the presence of infection is controlled by the host. Systemic maternal infections such as pyelonephritis or localized infections such as deciduitis can trigger parturition by the activation of the monocyte and macrophage system in peripheral bloo...

journal_title：Infectious disease clinics of North America

authors： Gomez R,Romero R,Edwin SS,David C

更新日期：1997-03-01 00:00:00

abstract：:Use of the most rapid and reliable laboratory tests for mycobacterial detection, identification, and susceptibility testing is important for TB control. In 1993, CDC experts made recommendations regarding optimal methods of mycobacterial testing (i.e., stains for AFB, culture, identification, and susceptibility testin...

journal_title：Infectious disease clinics of North America

authors： Woods GL

更新日期：2002-03-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. The mortality rate due to severe CAP has shown little improvement over the past few years, with a rate as high as 50% mainly in patients admitted to intensive care units. Death and adverse outcomes from CAP ...

journal_title：Infectious disease clinics of North America

authors： Sibila O,Restrepo MI,Anzueto A

更新日期：2013-03-01 00:00:00

abstract：:This article focuses on the use of immunoglobulin variable regions, including Id, anti-Id, anticlonotypes, and Id engineering as putative vaccines and vaccine strategies for infectious diseases; and specific discussion of Id systems involving antigenic determinants associated with potentially pathogenic organisms. ...

journal_title：Infectious disease clinics of North America

authors： Hefty PS,Kennedy RC

更新日期：1999-03-01 00:00:00