Abstract:
:Renal transplant recipients continue to have progressive kidney dysfunction and renal graft loss has been attributed to emerging opportunistic infections, specifically BK virus (BKV). BKV is postulated to be selected by the new potent immunosuppressive medications and to be an important factor in graft failure. The prevalence of BKV nephropathy (BKVN) is estimated to be 1% to 10% and renal allograft loss from BKVN has been estimated to occur in up to 50% of affected recipients. With the increasing recognition of BKV infection using PCR assays coupled with the immediate reduction in immunosuppression for BKVN, the incidence of graft failure secondary to BKVN may be decreasing.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
Balba GP,Javaid B,Timpone JG Jrdoi
10.1016/j.idc.2013.02.002subject
Has Abstractpub_date
2013-06-01 00:00:00pages
271-83issue
2eissn
0891-5520issn
1557-9824pii
S0891-5520(13)00016-0journal_volume
27pub_type
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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