Abstract:
:As the result of a formidable effort, the recent TB epidemic in the United States has abated; however, major questions remain as the risk of TB diminishes. Will we maintain an adequate public health effort not only to prevent another resurgence of TB but also to renew our pursuit of TB elimination? Do we have the will to extend the fight against TB worldwide as the TB threat in the United States declines? What is the best way to incorporate new diagnostic technology into routine practice? What are the best strategies for preventing and treating TB in AIDS patients? From the standpoint of NTM lung diseases, the major challenges are to educate clinicians about the variety and clinical presentation of NTM lung pathogens in order to recognize NTM lung disease as early as possible and to maximize treatment options. Hopefully, we can also improve upon the recent unprecedented progress in treatment regimens for NTM diseases of all types.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
Griffith DEdoi
10.1016/s0891-5520(05)70200-2subject
Has Abstractpub_date
1998-09-01 00:00:00pages
593-611issue
3eissn
0891-5520issn
1557-9824pii
S0891-5520(05)70200-2journal_volume
12pub_type
杂志文章,评审abstract::The identification of characteristic clinical, serologic, and immunologic responses to primary HIV infection has contributed greatly to our understanding of the natural history of HIV infection. Subjects usually present with a mononucleosis-like illness and during the period of primary infection there is a characteris...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
abstract::This article presents a discussion of the management of vascular prosthetic infections. The emphasis is on aortic graft infections, but other peripheral graft infections are also discussed. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::Influenza is a zoonotic respiratory virus that affects birds, mammals, and humans. Influenza viruses are unique in their genetic instability, which frequently results in antigenic drift or shift. Antigenic shifts are responsible for influenza epidemics. Influenza A pandemics have been responsible for millions of death...
journal_title:Infectious disease clinics of North America
pub_type: 历史文章,杂志文章
doi:10.1016/S0891-5520(03)00095-3
更新日期:2004-03-01 00:00:00
abstract::Oral mucositis is a serious complication of cancer therapy and in severely immunosuppressed patients. In immunosuppressed patients, the signs and symptoms of infection often are muted because of limited host response, and accurate diagnosis and appropriate treatment may be difficult. Prevention of mucosal breakdown, s...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2007.03.003
更新日期:2007-06-01 00:00:00
abstract::Ultrasound for diagnosis and staging of schistosomiasis and echinococcosis have paved the way over the past several decades for the application of ultrasound in tropical diseases. Until recently, the size and cost of ultrasound systems limited the application in low-resource settings. The increase in portable ultrasou...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2018.10.008
更新日期:2019-03-01 00:00:00
abstract::Urinary tract infections are common during infancy and childhood but are easily overlooked because of the unspecific symptoms. Prevention of renal scarring and its potential long-term consequences is possible but requires an increased awareness of the diagnosis, the imaging revealing anomalies within the urinary tract...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70370-6
更新日期:1997-09-01 00:00:00
abstract::Staphylococcus aureus is a leading cause of bacteremia and endocarditis. Over the past several years, the frequency of S. aureus bacteremia (SAB) has increased dramatically. This increasing frequency, coupled with increasing rates of antibiotic resistance, has renewed interest in this serious, common infection. S. aur...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(01)00003-4
更新日期:2002-06-01 00:00:00
abstract::KS is a major cause of morbidity and mortality among AIDS patients and a treatment problem in the sporadic cases that are not associated with HIV. All four forms of the disease are linked to a newly described herpesvirus, HHV-8 or KSHV, via strong epidemiologic associations and biologic plausibility as a causal agent....
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70409-8
更新日期:1998-03-01 00:00:00
abstract::Coccidioides, a fungus, is endemic to specific parts of the Western Hemisphere. This article examines the prevalence, pathogenesis and host defense, clinical manifestations, diagnosis, and treatment of coccidioidomycosis. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章
doi:10.1016/s0891-5520(02)00040-5
更新日期:2003-03-01 00:00:00
abstract::At the heart of imminent healthcare reform are the future physicians of this decade. Medical educators will want to stimulate a desire within students to practice humanitarian, cost-effective, community-oriented primary care. Further studies to examine the effects of medical student experiences in international electi...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::Tyrosine kinase inhibitors represent the standard of care for several diseases and drug targets in hematologic malignancies. Infectious complications vary by disease status and prior therapy, but overall incidence of infections generally is low. In chronic diseases, such as chronic myeloid leukemia and chronic lymphoc...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2020.02.008
更新日期:2020-06-01 00:00:00
abstract::Acute bacterial endocarditis (ABE) is clinically distinct from subacute bacterial endocarditis in terms of pathologic virulence, acuteness and severity of illness, complications, and prognosis. The term infectious endocarditis may be useful as a general term but conveys no meaningful clinical information. ABE presents...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70328-7
更新日期:1996-12-01 00:00:00
abstract::Fulminant meningitis requires aggressive management in an intensive care unit setting. The pathophysiology of the various factors that damage the central nervous system in this disease have been reviewed, as well as the management of the many complications of this serious, often devastating, infection. The etiologic a...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract::Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculi...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2007.12.009
更新日期:2008-06-01 00:00:00
abstract::Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear. Unfortunately, two of the pathogens for which these agent...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-09-01 00:00:00
abstract::Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of t...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70210-5
更新日期:1998-09-01 00:00:00
abstract::Infection is a well-described complication of cirrhosis and is a major cause of death in this population. This article examines the types of infections related with cirrhosis, such as bacteremia, urinary tract infections, meningitis, and others. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70150-1
更新日期:2001-06-01 00:00:00
abstract::Septic shock is a common life-threatening problem, usually presenting with fever, tachycardia, tachypnea, and often a source of infection. The cardiac index is increased, with a decreased systemic vascular resistance, and a reversibly decreased ejection fraction with an increased end diastolic volume. The myocardial d...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70298-1
更新日期:1996-06-01 00:00:00
abstract::AIDS is characteristically associated with several intracellular enteric protozoan infections that often cause chronic and sometimes fatal intractable large-volume diarrhea. Until the AIDS epidemic, several of these parasitic infections were almost unknown as causes of human disease. This article reviews the diseases ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1993-09-01 00:00:00
abstract::In the ICU, fever can be expected to accompany an extensive number of conditions of both infectious and noninfectious etiologies. It is crucial to identify the precise cause of fever, because certain conditions in either category may be life-threatening, whereas others require no treatment at all. It is important to r...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70294-4
更新日期:1996-03-01 00:00:00
abstract::Bronchiolitis is a lower respiratory tract illness caused by viral infection in children 2 years of age and younger, frequently associated with wheezing on physical examination. It is a common cause of hospitalization, particularly in patients with risk factors for more serious disease. The diagnosis can be made based...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2017.10.002
更新日期:2018-03-01 00:00:00
abstract::CSF evaluation is the single most important aspect of the laboratory diagnosis of meningitis. Analysis of the CSF abnormalities produced by bacterial, mycobacterial, and fungal infections may greatly facilitate diagnosis and direct initial therapy. Basic studies of CSF that should be performed in all patients with men...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
abstract::Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and mic...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2017.01.002
更新日期:2017-06-01 00:00:00
abstract::The number of species that comprise the family of Bartonellaceae, genus Bartonella, has recently increased from one to 11 species, five of which have been associated with different diseases and syndromes in humans. The rapidly growing number of human pathogens has led several investigators to regard bartonellosis and ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70215-4
更新日期:2000-03-01 00:00:00
abstract::This article reviews the changing epidemiology of infections associated with injection drug use, perceived barriers to care, features of successful programs for outpatient antimicrobial treatment, models of shared decision making at the time of discharge, and linkage to preventative care after antimicrobial completion...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2020.06.009
更新日期:2020-09-01 00:00:00
abstract::An increasing number of HIV-infected patients will require surgical therapy. The methods of diagnosis and therapeutic planning for HIV-infected patients are the same as for all other patients. Surgery should be advised if an operation is likely to have a positive effect on the patient's life. Most patients with AIDS w...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Antiviral agents aimed at treating HSV-2 chronically infected individuals have proven to be effective in the prevention of symptomatic genital herpes and the reduction of viral shedding. These agents play a key role in current HIV prevention trials that will assess the role of suppression of HSV-2 infection on the ris...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2005.04.005
更新日期:2005-06-01 00:00:00
abstract::Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection preventi...
journal_title:Infectious disease clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.idc.2019.08.005
更新日期:2019-12-01 00:00:00
abstract::This article focuses on the use of immunoglobulin variable regions, including Id, anti-Id, anticlonotypes, and Id engineering as putative vaccines and vaccine strategies for infectious diseases; and specific discussion of Id systems involving antigenic determinants associated with potentially pathogenic organisms. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70041-6
更新日期:1999-03-01 00:00:00
abstract::Antimicrobial stewardship programs aim to monitor, improve, and measure responsible antibiotic use. The intensive care unit (ICU), with its critically ill patients and prevalence of multiple drug-resistant pathogens, presents unique challenges. This article reviews approaches to stewardship with application to the ICU...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2017.05.002
更新日期:2017-09-01 00:00:00