Developments in STD/HIV interactions: the intertwining epidemics of HIV and HSV-2.

Abstract:

:Antiviral agents aimed at treating HSV-2 chronically infected individuals have proven to be effective in the prevention of symptomatic genital herpes and the reduction of viral shedding. These agents play a key role in current HIV prevention trials that will assess the role of suppression of HSV-2 infection on the risk for HIV acquisition and transmission. An added clinical benefit of treating HSV-2/HIV-coinfected individuals is the potential survival benefit, as suggested by earlier studies and by the recent findings that HSV-2/HIV dually infected individuals have higher viral loads. The results of the current HSV-2 suppression trials may provide additional tools to fight the global spread of HIV infection. Treatment of HSV-2/HIV dually infected individuals may prove to be a low-cost intervention to improve clinical outcomes and delay the need for antiretroviral therapy.

authors

Reynolds SJ,Quinn TC

doi

10.1016/j.idc.2005.04.005

subject

Has Abstract

pub_date

2005-06-01 00:00:00

pages

415-25

issue

2

eissn

0891-5520

issn

1557-9824

pii

S0891-5520(05)00036-X

journal_volume

19

pub_type

杂志文章,评审
  • Viral and fungal infections of the oral cavity in immunocompetent patients.

    abstract::Oral lesions are easily visualized and often are signs of systemic diseases. Clinical diagnosis of viral and fungal infections can sometimes be confusing because many lesions will have similar clinical presentations. This article reviews the more common viral- and fungal-associated lesions found in the oral cavity in ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70110-0

    authors: Glick M,Siegel MA

    更新日期:1999-12-01 00:00:00

  • Applications of therapy in animal models to bacterial infection in human disease.

    abstract::Animal models have proven to be invaluable in bridging the gap between in vitro susceptibility testing of an antibiotic and anticipating results obtained in clinical studies. Variables such as antibiotic concentration, inoculum of organism, and pharmacokinetic parameters of the drug can be carefully controlled to prov...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Tunkel AR,Scheld WM

    更新日期:1989-09-01 00:00:00

  • Invasive Candidiasis.

    abstract::Invasive candidiasis is a collective term that refers to a group of infectious syndromes caused by a variety of species of Candida, 5 of which cause most cases. Candidemia is the most commonly recognized syndrome associated with invasive candidiasis. Certain conditions may influence the likelihood for one species vers...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2015.10.013

    authors: McCarty TP,Pappas PG

    更新日期:2016-03-01 00:00:00

  • Recommended schedules for routine immunization of children and adults.

    abstract::Vaccine recommendations continue to evolve as a result of new vaccines, safety considerations, changing disease incidence (e.g., polio), and public health priorities. The pace of discovery is accelerating and advisory committees will need to respond accordingly. Each vaccine, new or old, will be required to earn its p...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70264-6

    authors: Gardner P,Peter G

    更新日期:2001-03-01 00:00:00

  • Meningitis due to protozoa and helminths.

    abstract::This article reviews the microbiology, pathogenesis, epidemiology, clinical manifestations, diagnostic tests, and recent advances in the therapy of protozoan and helminthic infections of the central nervous system, with more emphasis given to protozoan than to helminthic infections. ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Niu MT,Duma RJ

    更新日期:1990-12-01 00:00:00

  • Norovirus Infection in Older Adults: Epidemiology, Risk Factors, and Opportunities for Prevention and Control.

    abstract::Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outc...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2017.07.012

    authors: Cardemil CV,Parashar UD,Hall AJ

    更新日期:2017-12-01 00:00:00

  • Mycobacterial diseases. Tuberculosis and Mycobacterium avium complex.

    abstract::Pulmonary or extrapulmonary tuberculosis occurs in 5 to 35 per cent of AIDS patients, frequently precedes the diagnosis of AIDS, and is increasing in incidence. Clinically, AIDS-associated tuberculosis is similar in presentation to progressive, primary tuberculosis and can be treated effectively with standard antitube...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Jacobson MA

    更新日期:1988-06-01 00:00:00

  • Update and Commentary on Four Emerging Tick-Borne Infections: Ehrlichia muris-like Agent, Borrelia miyamotoi, Deer Tick Virus, Heartland Virus, and Whether Ticks Play a Role in Transmission of Bartonella henselae.

    abstract::Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris-like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus was provided and criti...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2015.02.009

    authors: Wormser GP,Pritt B

    更新日期:2015-06-01 00:00:00

  • Strategies to improve antibiotic use.

    abstract::The desideratum of "appropriate" antibiotic therapy include efficacy, safety, and low cost. Strategies for achieving these goals include education, control of the hospital formulary, written justification forms and automatic stop orders, ongoing utilization review, restriction, required consultation, control of labora...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Bryan CS

    更新日期:1989-12-01 00:00:00

  • Coccidioidomycosis.

    abstract::Coccidioides, a fungus, is endemic to specific parts of the Western Hemisphere. This article examines the prevalence, pathogenesis and host defense, clinical manifestations, diagnosis, and treatment of coccidioidomycosis. ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章

    doi:10.1016/s0891-5520(02)00040-5

    authors: Chiller TM,Galgiani JN,Stevens DA

    更新日期:2003-03-01 00:00:00

  • Reactive Arthritis.

    abstract::Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and mic...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2017.01.002

    authors: Schmitt SK

    更新日期:2017-06-01 00:00:00

  • Infection in the elderly.

    abstract::Many functional, demographic, and immunologic changes associated with aging are responsible for increasing the incidence and severity of infectious diseases in the elderly. Management is complicated by age-related organ system changes. Because many of the elderly are on multiple medications for underlying illnesses, a...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2007.07.006

    authors: Htwe TH,Mushtaq A,Robinson SB,Rosher RB,Khardori N

    更新日期:2007-09-01 00:00:00

  • The role of the clinical microbiology laboratory in the management of Clostridium difficile-associated diarrhea.

    abstract::Nosocomial diarrhea due to infection with C. difficile is a major health care problem, causing 20% to 30% of institutionally acquired diarrhea and affecting up to 8% of hospitalized patients. The clinical microbiology laboratory should be able to provide both diagnostic and epidemiologic services for institutions wher...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Peterson LR,Kelly PJ

    更新日期:1993-06-01 00:00:00

  • Infectious diarrhea in history.

    abstract::Throughout history, infectious diarrhea has been associated with crowding, poor sanitation, and war. Although descriptions of infectious diarrhea exist in the earliest records of civilization, effective measures for prevention were not widely or consistently used until the modern era of active public health promotion....

    journal_title:Infectious disease clinics of North America

    pub_type: 历史文章,杂志文章

    doi:10.1016/j.idc.2004.01.006

    authors: Lim ML,Wallace MR

    更新日期:2004-06-01 00:00:00

  • Advances in the imaging of renal infection. Helical CT and modern coordinated imaging.

    abstract::Traditionally, imaging of renal infections was largely through a multimodality approach. Excretory urography, ultrasonography, nuclear scintigraphy, and CT all played major roles; however, in recent years, CT has increased in prominence in the imaging and evaluation of renal infection. Part of the reason for this tren...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70380-9

    authors: Kaplan DM,Rosenfield AT,Smith RC

    更新日期:1997-09-01 00:00:00

  • Approach to immunization in the immunosuppressed host.

    abstract::An ever-increasing population of immunocompromised individuals, including not only the burgeoning AIDS population but also those patients whose host defenses have been damaged by a wide variety of diseases and their therapies, requires prophylaxis against infectious diseases. Existing vaccines can provide some benefit...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Hibberd PL,Rubin RH

    更新日期:1990-03-01 00:00:00

  • Human T-cell lymphotropic virus-I in Latin America.

    abstract::HTLV-1 infection is endemic in several Latin American countries. HTLV-1-associated myelophathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia lymphoma (ATLL) are emerging diseases in the region. Documented risk factors for acquiring the virus include breast-feeding, contaminated blood transfusion, an...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70225-7

    authors: Gotuzzo E,Arango C,de Queiroz-Campos A,Istúriz RE

    更新日期:2000-03-01 00:00:00

  • Gynecologic issues in the HIV-infected woman.

    abstract::In this article, gynecologic conditions of increased importance in the HIV-infected woman are discussed. Women living with HIV may have an increase in menstrual disorders, lower genital tract neoplasias, gynecologic surgery, and sexually transmitted infections. The literature relevant to choosing a method of contracep...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2008.05.006

    authors: Cejtin HE

    更新日期:2008-12-01 00:00:00

  • Assays for antibodies to varicella-zoster virus.

    abstract::Anti-varicella-zoster virus serum antibody assays and their use in vaccine development are described. Of particular interest are FAMA and neutralization assays and the gpELISA. These and other assays are compared and summarized in terms of characteristics including biologic relevance, sensitivity, specificity, and sui...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70311-1

    authors: Krah DL

    更新日期:1996-09-01 00:00:00

  • Laboratory issues in the detection and reporting of antibacterial resistance.

    abstract::The emergence of antimicrobial resistance among several common bacterial pathogens requires that clinical microbiology laboratories have the ability to promptly and accurately recognize resistance in patients' isolates. Laboratories have several options for performing routine susceptibility testing, including the brot...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70390-1

    authors: Jorgensen JH

    更新日期:1997-12-01 00:00:00

  • Meta-analytical studies on the epidemiology, prevention, and treatment of human immunodeficiency virus infection.

    abstract::Since the beginning of the epidemic, extensive research has been conducted in the field of HIV infection. Original research and subsequent meta-analyses have contributed to a better understanding of the disease. Epidemiologic research has shown, for example, that male circumcision reduces the risk of female-to-male tr...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2009.01.013

    authors: Vergidis PI,Falagas ME,Hamer DH

    更新日期:2009-06-01 00:00:00

  • Treating foodborne illness.

    abstract::In healthy adults and children in developed countries, most foodborne and water-borne infections are short-lived and resolve without specific treatment. In developing areas, these infections may produce acute mortality and chronic morbidity caused by developmental impairment. Immune-compromised hosts are at increased ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2013.05.006

    authors: Steiner T

    更新日期:2013-09-01 00:00:00

  • Emerging issues in blood safety.

    abstract::Improvements in donor selection, testing of donors for markers of infection, and viral inactivation of plasma-derived products have helped reduce the risk of transfusion-associated infections, including hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency viruses (HIV). The potential for transmission of em...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70419-0

    authors: Chamberland M,Khabbaz RF

    更新日期:1998-03-01 00:00:00

  • Amebic liver abscess.

    abstract::Amebiasis is a widespread parasitic disease caused by Entamoeba histolytica. This protozoan organism is the third leading parasitic cause of death in the developing world and is an important health risk to travelers in endemic areas. Amebiasis most commonly results in asymptomatic colonization of the gastrointestinal ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/s0891-5520(05)70121-5

    authors: Hughes MA,Petri WA Jr

    更新日期:2000-09-01 00:00:00

  • Prevention of traveler's diarrhea.

    abstract::Preventing traveler's diarrhea is usually a matter of common sense, good luck, and the host's ability to defend against enteric pathogens, particularly enterotoxigenic Escherichia coli. Untreated tap water, ice cubes, unpasteurized milk products, salads, food from street vendors, and dining in unhygienic-appearing res...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Tellier R,Keystone JS

    更新日期:1992-06-01 00:00:00

  • Impact of human immunodeficiency virus infection on women and infants.

    abstract::Infection with HIV is a problem of growing magnitude among women and children in the United States. During 1991, AIDS will be among the five leading causes of death for women of childbearing age. Over 80% of children with HIV have acquired the infection vertically, and AIDS is now a leading cause of death of children ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Kline MW,Shearer WT

    更新日期:1992-03-01 00:00:00

  • Viral Hepatitis: Etiology, Epidemiology, Transmission, Diagnostics, Treatment, and Prevention.

    abstract::Viral hepatitis is a major global public health problem affecting hundreds of millions of people and is associated with significant morbidity and mortality. Five major biologically unrelated hepatotropic viruses cause most of the global burden of viral hepatitis. Hepatitis B and hepatitis C are associated with a signi...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2019.08.004

    authors: Lanini S,Ustianowski A,Pisapia R,Zumla A,Ippolito G

    更新日期:2019-12-01 00:00:00

  • Role of Procalcitonin in the Management of Infected Patients in the Intensive Care Unit.

    abstract::The combination of molecular pathogen diagnostics and the biomarker procalcitonin (PCT) are changing the use of antimicrobials in patients admitted to critical care units with severe community-acquired pneumonia, possible septic shock, or other clinical syndromes. An elevated serum PCT level is good supportive evidenc...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2017.05.003

    authors: Gilbert DN

    更新日期:2017-09-01 00:00:00

  • Drug-Resistant Tuberculosis: Challenges and Progress.

    abstract::Antimicrobial resistance is a natural evolutionary process, which in the case of Mycobacterium tuberculosis is based on spontaneous chromosomal mutations, meaning that well-designed combination drug regimens provided under supervised therapy will prevent the emergence of drug-resistant strains. Unfortunately, limited ...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:10.1016/j.idc.2016.02.010

    authors: Kurz SG,Furin JJ,Bark CM

    更新日期:2016-06-01 00:00:00

  • Primary human immunodeficiency virus infection. Clinical and serologic aspects.

    abstract::The identification of characteristic clinical, serologic, and immunologic responses to primary HIV infection has contributed greatly to our understanding of the natural history of HIV infection. Subjects usually present with a mononucleosis-like illness and during the period of primary infection there is a characteris...

    journal_title:Infectious disease clinics of North America

    pub_type: 杂志文章,评审

    doi:

    authors: Tindall B,Cooper DA,Donovan B,Penny R

    更新日期:1988-06-01 00:00:00