Abstract：
:Invasive candidiasis is a collective term that refers to a group of infectious syndromes caused by a variety of species of Candida, 5 of which cause most cases. Candidemia is the most commonly recognized syndrome associated with invasive candidiasis. Certain conditions may influence the likelihood for one species versus another in a specific clinical scenario, and this can have important implications for selection of antifungal therapy and the duration of treatment. Molecular diagnostic technology plays an ever-increasing role as an adjunct to traditional culture-based diagnostics, offering significant potential toward improvement in patient care.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
McCarty TP,Pappas PGdoi
10.1016/j.idc.2015.10.013subject
Has Abstractpub_date
2016-03-01 00:00:00pages
103-24issue
1eissn
0891-5520issn
1557-9824pii
S0891-5520(15)00114-2journal_volume
30pub_type
杂志文章,评审abstract：:AIDS is characteristically associated with several intracellular enteric protozoan infections that often cause chronic and sometimes fatal intractable large-volume diarrhea. Until the AIDS epidemic, several of these parasitic infections were almost unknown as causes of human disease. This article reviews the diseases ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1993-09-01 00:00:00
abstract：:Although infective endocarditis is certainly not the most common infection seen in injecting drug users, it is the infection that clinicians most commonly think of when they consider infectious complications of injected drug use. The microbiology of infective endocarditis in injection drug users has remained relativel...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0891-5520(02)00019-3
更新日期：2002-09-01 00:00:00
abstract：:Since the introduction of the floroquinolones for clinical use in the late 1980s, they have been used successfully for a large number of clinical situations. As experience accumulates, the indications and optimal use of these agents gradually become more clear. Unfortunately, two of the pathogens for which these agent...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1995-09-01 00:00:00
abstract：:Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of t...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0891-5520(05)70210-5
更新日期：1998-09-01 00:00:00
abstract：:Population growth in the twentieth century is at its highest level in history, with the world's population now doubling in approximately 40 years. An unprecedented 90 million people are being added worldwide each year, with most of the growth taking place in the developing world. The implications of this rate of growt...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection preventi...
journal_title：Infectious disease clinics of North America
pub_type： 历史文章,杂志文章,评审
doi：10.1016/j.idc.2019.08.005
更新日期：2019-12-01 00:00:00
abstract：:Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2009.04.003
更新日期：2009-09-01 00:00:00
abstract：:In this article, gynecologic conditions of increased importance in the HIV-infected woman are discussed. Women living with HIV may have an increase in menstrual disorders, lower genital tract neoplasias, gynecologic surgery, and sexually transmitted infections. The literature relevant to choosing a method of contracep...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2008.05.006
更新日期：2008-12-01 00:00:00
abstract：:Urinary tract infections are common during infancy and childhood but are easily overlooked because of the unspecific symptoms. Prevention of renal scarring and its potential long-term consequences is possible but requires an increased awareness of the diagnosis, the imaging revealing anomalies within the urinary tract...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0891-5520(05)70370-6
更新日期：1997-09-01 00:00:00
abstract：:Staphylococcus aureus is an important pathogen in the hospital and in the community, and it is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S aureus is needed. The most extensively tested vaccine against S aureus, which is a capsular polysaccharide-based vaccine known as S...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2008.10.005
更新日期：2009-03-01 00:00:00
abstract：:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2017.07.017
更新日期：2017-12-01 00:00:00
abstract：:Genome-wide association studies have identified polymorphisms located near the gene encoding IL28B, which turned out to be the best predictor of response to pegylated interferon plus ribavirin for chronic hepatitis C virus (HCV) genotype 1 infection. This association was extended to spontaneous clearance of HCV, sugge...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2012.08.010
更新日期：2012-12-01 00:00:00
abstract：:Critical-care units can be barometers for appropriate antimicrobial use. There, life and death hang on empirical antimicrobial therapy for treatment of infectious diseases. With increasing therapeutic empiricism, triple-drug, broad-spectrum regimens are often necessary, but cannot be continued without fear of the doub...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2009.04.015
更新日期：2009-09-01 00:00:00
abstract：:The penicillins continue to be important antibiotics for the treatment and prophylaxis of many infectious diseases. The emergence of resistant microorganism has led to the development of newer penicillin compounds that have extended spectrums of antimicrobial activity. Beta-lactamase production by many pathogenic bact...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-09-01 00:00:00
abstract：:Serum protein binding of antimicrobials can reduce antimicrobial activity, restrict tissue distribution, and delay drug elimination. Binding percentages of 80 per cent or more have the potential to significantly reduce free drug levels and affect therapeutic efficacy in patients. However, binding-induced alterations i...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-09-01 00:00:00
abstract：:Vancomycin and daptomycin are options for the initial treatment of patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Treatment options for persistent MRSA bacteremia or bacteremia due to vancomycin-intermediate or vancomycin-resistant strains include daptomycin, ceftaroline, and combination ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2020.04.003
更新日期：2020-12-01 00:00:00
abstract：:Although a small number of infections in total joint replacements are blood borne from distant sources, most infections appear to have been derived at operation. Strenuous attempts to reduce this risk by cleaning the air in the wound environment, coupled with prophylactic antibiotics, have reduced infection rates by a...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1990-09-01 00:00:00
abstract：:Many functional, demographic, and immunologic changes associated with aging are responsible for increasing the incidence and severity of infectious diseases in the elderly. Management is complicated by age-related organ system changes. Because many of the elderly are on multiple medications for underlying illnesses, a...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2007.07.006
更新日期：2007-09-01 00:00:00
abstract：:Pulmonary or extrapulmonary tuberculosis occurs in 5 to 35 per cent of AIDS patients, frequently precedes the diagnosis of AIDS, and is increasing in incidence. Clinically, AIDS-associated tuberculosis is similar in presentation to progressive, primary tuberculosis and can be treated effectively with standard antitube...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-06-01 00:00:00
abstract：:Antiretroviral management of treatment-naive patients begins with the decision of when to start treatment. Current treatment guidelines suggest starting therapy in anyone with AIDS, HIV-related symptoms, or a CD4 cell count less than 200/mm3 regardless of symptoms. Starting treatment in asymptomatic patients with CD4 ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章
doi：10.1016/j.idc.2007.01.002
更新日期：2007-03-01 00:00:00
abstract：:Infections accompanying severe pancreatitis are secondary and of three types: infected pancreatic necrosis, infected pseudocyst (including peripancreatic fluid collection), and pancreatic abscess. The first is an earlier, more morbid process, with antibiotics supportive and surgical debridement necessary. The latter t...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1992-09-01 00:00:00
abstract：:Various nontuberculous mycobacteria can cause infection of skin and soft tissues. These organisms are also known as atypical mycobacteria, anonymous mycobacteria, and mycobacteria other than tuberculosis. These organisms are much more common causes of cutaneous infection than Mycobacterium tuberculosis. Infections cau...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1994-09-01 00:00:00
abstract：:This article presents a discussion of the management of vascular prosthetic infections. The emphasis is on aortic graft infections, but other peripheral graft infections are also discussed. ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1989-06-01 00:00:00
abstract：:Erythema migrans (EM) is the most common objective manifestation of Borrelia burgdorferi infection. Systemic symptoms are usually present. Most patients do not recall a preceding tick bite. Despite a characteristic appearance, EM is not pathognomonic for Lyme disease and must be distinguished from other similar appear...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2015.02.001
更新日期：2015-06-01 00:00:00
abstract：:Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris-like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus was provided and criti...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2015.02.009
更新日期：2015-06-01 00:00:00
abstract：:The most frequent and best-studied agent of urinary tract infection (UTI) is Escherichia coli, which serves as a useful model pathogen for understanding microbial virulence in relation to UTI pathogenesis. The E. coli strains that cause most UTIs and other extraintestinal E. coli infections represent a highly speciali...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/s0891-5520(03)00027-8
更新日期：2003-06-01 00:00:00
abstract：:The approach to neurologic diagnosis and management of HIV-infected and AIDS patients follows that used in general neurologic practice but takes into account the altered probabilities of differential diagnosis in this group of patients. Clinical and neurodiagnostic evaluations, when pursued with a background understan...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1988-06-01 00:00:00
abstract：:When properly used, disinfection and sterilization can ensure the safe use of invasive and noninvasive medical devices. The method of disinfection and sterilization depends on the intended use of the medical device: critical items (contact sterile tissue) must be sterilized before use; semicritical items (contact muco...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2016.04.002
更新日期：2016-09-01 00:00:00
abstract：:Since the beginning of the epidemic, extensive research has been conducted in the field of HIV infection. Original research and subsequent meta-analyses have contributed to a better understanding of the disease. Epidemiologic research has shown, for example, that male circumcision reduces the risk of female-to-male tr...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：10.1016/j.idc.2009.01.013
更新日期：2009-06-01 00:00:00
abstract：:Water serves as a major reservoir for the environmental mycobacteria. Many cases of cutaneous mycobacterial disease result from water exposure. The current theory of the pathogenesis of M. avium complex lung disease involves inhalation of organisms aerosolized from surface water. Disseminated M. avium disease in AIDS ...
journal_title：Infectious disease clinics of North America
pub_type： 杂志文章,评审
doi：
更新日期：1987-09-01 00:00:00
