Abstract:
:Infection with HIV is a problem of growing magnitude among women and children in the United States. During 1991, AIDS will be among the five leading causes of death for women of childbearing age. Over 80% of children with HIV have acquired the infection vertically, and AIDS is now a leading cause of death of children in many urban areas of the United States. Gender and age have important influences on the progression of HIV disease and on the occurrence of complicating illnesses. Zidovudine can slow HIV disease progression, and several regimens of prophylaxis are effective against P. carinii pneumonia, which is the leading cause of death among adults and children with AIDS. Intravenous immunoglobulin may be effective for prevention of serious infections in some children with symptomatic HIV infection. Ultimately, prevention of HIV infection among women and children depends on targeted education and, possibly, the development of medical strategies for interruption of vertical transmission.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
Kline MW,Shearer WTsubject
Has Abstractpub_date
1992-03-01 00:00:00pages
1-17issue
1eissn
0891-5520issn
1557-9824journal_volume
6pub_type
杂志文章,评审abstract::This article presents a discussion of the management of vascular prosthetic infections. The emphasis is on aortic graft infections, but other peripheral graft infections are also discussed. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-06-01 00:00:00
abstract::Antiviral agents aimed at treating HSV-2 chronically infected individuals have proven to be effective in the prevention of symptomatic genital herpes and the reduction of viral shedding. These agents play a key role in current HIV prevention trials that will assess the role of suppression of HSV-2 infection on the ris...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2005.04.005
更新日期:2005-06-01 00:00:00
abstract::No practitioner can hide from HIV. Patients infected with HIV are treated in every type of practice setting as the number of cases increases at an alarming rate. This article provides 10 basic guidelines for the care of HIV-infected patients. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章
doi:
更新日期:1994-06-01 00:00:00
abstract::An increasing number of HIV-infected patients will require surgical therapy. The methods of diagnosis and therapeutic planning for HIV-infected patients are the same as for all other patients. Surgery should be advised if an operation is likely to have a positive effect on the patient's life. Most patients with AIDS w...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-09-01 00:00:00
abstract::Successful antimicrobial stewardship programs rely on engagement with hospital administrators. Antimicrobial stewards should understand the unique pressures and demands of hospital and health system administration and be familiar with key terminology and regulatory requirements. This article provides guidance on strat...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2019.10.003
更新日期:2020-03-01 00:00:00
abstract::The desideratum of "appropriate" antibiotic therapy include efficacy, safety, and low cost. Strategies for achieving these goals include education, control of the hospital formulary, written justification forms and automatic stop orders, ongoing utilization review, restriction, required consultation, control of labora...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-12-01 00:00:00
abstract::Global eradication of smallpox, elimination of poliomyelitis in the Western Hemisphere, and a 90% decrease in Haemophilus influenzae meningitis in the Western Hemisphere mark some of the achievements of immunization programs around the world. Yet many serious problems continue to exist, particularly in the developing ...
journal_title:Infectious disease clinics of North America
pub_type: 历史文章,杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract::In this article, gynecologic conditions of increased importance in the HIV-infected woman are discussed. Women living with HIV may have an increase in menstrual disorders, lower genital tract neoplasias, gynecologic surgery, and sexually transmitted infections. The literature relevant to choosing a method of contracep...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2008.05.006
更新日期:2008-12-01 00:00:00
abstract::Acquired immunodeficiency syndrome (AIDS) is the lethal end stage of a sexually transmitted disease caused by a virus that is producing the major epidemic of our century. In this article we describe the history and epidemiology of AIDS and the disease states associated with infection with the human immunodeficiency vi...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-03-01 00:00:00
abstract::Living safely after organ transplantation starts before transplant and continues after transplant. To minimize a solid organ transplant (SOT) recipient's risk for infection and risk for injury, it is important to plan for numerous potential exposures after transplant. These include potential exposure to others with vi...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2018.04.014
更新日期:2018-09-01 00:00:00
abstract::Staphylococcus aureus is a leading cause of bacteremia and endocarditis. Over the past several years, the frequency of S. aureus bacteremia (SAB) has increased dramatically. This increasing frequency, coupled with increasing rates of antibiotic resistance, has renewed interest in this serious, common infection. S. aur...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(01)00003-4
更新日期:2002-06-01 00:00:00
abstract::Catheter-related bloodstream infections (CRBSI) are responsible for significant morbidity, mortality, and excess health care costs. It is increasingly evident that many CRBSI can be prevented with current knowledge and techniques. Preventive measures can be broadly grouped into clinical practice-based interventions an...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2016.07.001
更新日期:2016-12-01 00:00:00
abstract::Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection preventi...
journal_title:Infectious disease clinics of North America
pub_type: 历史文章,杂志文章,评审
doi:10.1016/j.idc.2019.08.005
更新日期:2019-12-01 00:00:00
abstract::Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2009.04.003
更新日期:2009-09-01 00:00:00
abstract::Invasive candidiasis is a collective term that refers to a group of infectious syndromes caused by a variety of species of Candida, 5 of which cause most cases. Candidemia is the most commonly recognized syndrome associated with invasive candidiasis. Certain conditions may influence the likelihood for one species vers...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2015.10.013
更新日期:2016-03-01 00:00:00
abstract::The emergence of antimicrobial resistance among several common bacterial pathogens requires that clinical microbiology laboratories have the ability to promptly and accurately recognize resistance in patients' isolates. Laboratories have several options for performing routine susceptibility testing, including the brot...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70390-1
更新日期:1997-12-01 00:00:00
abstract::Acute bacterial endocarditis (ABE) is clinically distinct from subacute bacterial endocarditis in terms of pathologic virulence, acuteness and severity of illness, complications, and prognosis. The term infectious endocarditis may be useful as a general term but conveys no meaningful clinical information. ABE presents...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70328-7
更新日期:1996-12-01 00:00:00
abstract::Considering experience acquired in the past years, it seems as though physicians have reached a plateau in the frequency of peritonitis. A peritonitis rate of 1 every 2 patient years may be acceptable. Further reduction of this peritonitis rate will require inordinately large efforts on all fronts. One will have to co...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70171-9
更新日期:2001-09-01 00:00:00
abstract::Norovirus is the leading cause of acute gastroenteritis. In older adults, it is responsible for an estimated 3.7 million illnesses; 320,000 outpatient visits; 69,000 emergency department visits; 39,000 hospitalizations; and 960 deaths annually in the United States. Older adults are particularly at risk for severe outc...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2017.07.012
更新日期:2017-12-01 00:00:00
abstract::Although only few cases of diphtheria are reported annually in the United States, substantial numbers of adults have declining levels of protective serum antitoxin. A recent outbreak of diphtheria in Sweden emphasizes the importance of reimmunizing adults in diphtheria toxoid, included as part of routine use of tetanu...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
abstract::Fulminant meningitis requires aggressive management in an intensive care unit setting. The pathophysiology of the various factors that damage the central nervous system in this disease have been reviewed, as well as the management of the many complications of this serious, often devastating, infection. The etiologic a...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1989-03-01 00:00:00
abstract::HA-1A is a human monoclonal IgM antibody that binds to endotoxin. The results of the clinical trials of HA-1A demonstrate that HA-1A reduces mortality among patients with sepsis and gram-negative bacteremia. Secondary endpoints, including resolution of organ failure, discharge from intensive care unit, and discharge f...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1992-03-01 00:00:00
abstract::Water serves as a major reservoir for the environmental mycobacteria. Many cases of cutaneous mycobacterial disease result from water exposure. The current theory of the pathogenesis of M. avium complex lung disease involves inhalation of organisms aerosolized from surface water. Disseminated M. avium disease in AIDS ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-09-01 00:00:00
abstract::This article familiarizes the clinician with the principles of bacterial susceptibility testing and reporting to facilitate communication with the clinical microbiology laboratory. The emergence of resistance in nearly all commonly isolated bacterial organisms has highlighted the need for ongoing dialogue between the ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2004.04.001
更新日期:2004-09-01 00:00:00
abstract::The approach to neurologic diagnosis and management of HIV-infected and AIDS patients follows that used in general neurologic practice but takes into account the altered probabilities of differential diagnosis in this group of patients. Clinical and neurodiagnostic evaluations, when pursued with a background understan...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
abstract::This article provides background information on the pharmacokinetics of antibacterial agents in patients who have normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. The use of serum levels; newer strategies for cefazolin, va...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2009.06.009
更新日期:2009-12-01 00:00:00
abstract::Cytomegalovirus (CMV) continues to be responsible for a substantial fraction of the morbidity and mortality that follows organ transplantation. The three major consequences of CMV infection are CMV disease (encompassing a range of clinical illness), superinfection with opportunistic pathogens, and injury to the transp...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1995-12-01 00:00:00
abstract::Cellulitis is a common clinical diagnosis in the outpatient and inpatient setting; studies have demonstrated a surprisingly high misdiagnosis rate: nearly one-third of cases are other conditions (ie, pseudocellulitis). This high rate of misdiagnosis is thought to contribute to nearly $515 million in avoidable health c...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2020.10.001
更新日期:2021-03-01 00:00:00
abstract::Prevention is the best method for avoiding potentially serious complications of Lyme and other tick-borne diseases. In this article, we discuss preventative measures that can be used by individuals or communities. Among the topics discussed are personal protective measures, tick reduction, reservoir reduction, and vac...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2008.03.007
更新日期:2008-09-01 00:00:00
abstract::Staphylococcus aureus is an important pathogen in the hospital and in the community, and it is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S aureus is needed. The most extensively tested vaccine against S aureus, which is a capsular polysaccharide-based vaccine known as S...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2008.10.005
更新日期:2009-03-01 00:00:00