Abstract：
:HTLV-1 infection is endemic in several Latin American countries. HTLV-1-associated myelophathy/tropical spastic paraparesis (HAM/TSP) and adult T-cell leukemia lymphoma (ATLL) are emerging diseases in the region. Documented risk factors for acquiring the virus include breast-feeding, contaminated blood transfusion, and sexual intercourse, all of which are amenable to prevention efforts. Strongyloides stercoralis hyperinfection syndrome and therapeutic failure in apparently healthy patients with nondisseminated strongyloidiasis may be markers of HTLV-1 infection. HTLV-1 co-infection may adversely effect the clinical course of scabies and HIV disease. The new enzyme-linked immunosorbent assays (ELISA) are sensitive and specific, and Western blot technology is reliable for differentiating HTLV-1 from less common HTLV-2. HTLV-1 screening of blood donors and individuals with any disorder that suggests infection has become a necessity in Latin America to prevent the spread of this important emerging pathogen.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
Gotuzzo E,Arango C,de Queiroz-Campos A,Istúriz REdoi
10.1016/s0891-5520(05)70225-7subject
Has Abstractpub_date
2000-03-01 00:00:00pages
211-39, x-xiissue
1eissn
0891-5520issn
1557-9824pii
S0891-5520(05)70225-7journal_volume
14pub_type
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