Immunotherapy with antibodies to core lipopolysaccharide: a critical appraisal.

abstract：:In the preantibiotic era, deep fascial space infections were common, and physicians were well acquainted with their complex and sometimes subtle manifestations. Widespread use of antibiotics, however, not only has significantly decreased the incidence of deep neck infections but also has altered their clinical manifes...

journal_title：Infectious disease clinics of North America

authors： Blomquist IK,Bayer AS

更新日期：1988-03-01 00:00:00

abstract：:The diagnostic approach to the compromised host with CNS infection depends on an analysis of the patient's clinical manifestations of CNS disease, the acuteness or subacuteness of the clinical presentation, and an analysis of the type of immune defect compromising the patient's host defenses. Most patients with CNS in...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:A wide range of soft-tissue infections can occur in diabetic patients, the consequences of which can be devastating. Early recognition and intervention, which may involve both surgical and medical approaches, can improve clinical outcomes. ...

journal_title：Infectious disease clinics of North America

authors： Sentochnik DE

更新日期：1995-03-01 00:00:00

abstract：:Mass gatherings have attracted the attention of the medical community because of the increased demand made on existing services and the potential for public health problems resulting from changes in population dynamics and behaviors. Crowding, lack of hygiene, and rapid population movement at mass gatherings can lead ...

journal_title：Infectious disease clinics of North America

authors： Al-Tawfiq JA,Memish ZA

更新日期：2012-09-01 00:00:00

abstract：:CSF evaluation is the single most important aspect of the laboratory diagnosis of meningitis. Analysis of the CSF abnormalities produced by bacterial, mycobacterial, and fungal infections may greatly facilitate diagnosis and direct initial therapy. Basic studies of CSF that should be performed in all patients with men...

journal_title：Infectious disease clinics of North America

authors： Greenlee JE

更新日期：1990-12-01 00:00:00

abstract：:Septic arthritis still continues to be a common and serious problem at major urban medical centers and is one of the most rapidly destructive forms of acute arthritis. The yearly incidence of bacterial arthritis varies from 2 to 10 per 100,000 in the general population to 30 to 70 per 100,000 in patients with rheumato...

journal_title：Infectious disease clinics of North America

authors： García-De La Torre I

更新日期：2006-12-01 00:00:00

abstract：:Cytomegalovirus (CMV) continues to be responsible for a substantial fraction of the morbidity and mortality that follows organ transplantation. The three major consequences of CMV infection are CMV disease (encompassing a range of clinical illness), superinfection with opportunistic pathogens, and injury to the transp...

journal_title：Infectious disease clinics of North America

authors： Hibberd PL,Snydman DR

更新日期：1995-12-01 00:00:00

abstract：:The penicillins continue to be important antibiotics for the treatment and prophylaxis of many infectious diseases. The emergence of resistant microorganism has led to the development of newer penicillin compounds that have extended spectrums of antimicrobial activity. Beta-lactamase production by many pathogenic bact...

journal_title：Infectious disease clinics of North America

authors： Bush LM,Calmon J,Johnson CC

更新日期：1989-09-01 00:00:00

abstract：:Ebola virus disease (EVD) is a deadly zoonotic disease caused by the Ebola virus. There is no specific treatment approved for EVD. Supportive care and management of complications are mainstays of treatment. Effective outbreak control requires a multidisciplinary team effort applying case management, infection preventi...

journal_title：Infectious disease clinics of North America

authors： Nicastri E,Kobinger G,Vairo F,Montaldo C,Mboera LEG,Ansunama R,Zumla A,Ippolito G

更新日期：2019-12-01 00:00:00

abstract：:Heart transplant remain the definitive therapy for end-stage heart failure but is limited by the availability of suitable donors. Ventricular assist devices (VAD) are designed as mechanical pumps to supplement or replace the function of damaged ventricles and maintain appropriate blood flow in patients with end-stage ...

journal_title：Infectious disease clinics of North America

authors： Teoh TK,Hannan MM

更新日期：2018-12-01 00:00:00

abstract：:Infections accompanying severe pancreatitis are secondary and of three types: infected pancreatic necrosis, infected pseudocyst (including peripancreatic fluid collection), and pancreatic abscess. The first is an earlier, more morbid process, with antibiotics supportive and surgical debridement necessary. The latter t...

journal_title：Infectious disease clinics of North America

authors： Traverso LW

更新日期：1992-09-01 00:00:00

abstract：:Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and mic...

journal_title：Infectious disease clinics of North America

authors： Schmitt SK

更新日期：2017-06-01 00:00:00

abstract：:Traditionally, imaging of renal infections was largely through a multimodality approach. Excretory urography, ultrasonography, nuclear scintigraphy, and CT all played major roles; however, in recent years, CT has increased in prominence in the imaging and evaluation of renal infection. Part of the reason for this tren...

journal_title：Infectious disease clinics of North America

authors： Kaplan DM,Rosenfield AT,Smith RC

更新日期：1997-09-01 00:00:00

abstract：:Changes that occur in the pharmacology of drugs in the elderly must be considered in the use of antimicrobial agents. Although absorption of orally administered drugs is not affected in a significant way, renal function decreases, drug-drug interactions increase, compliance with regimens may be decreased, and drug tox...

journal_title：Infectious disease clinics of North America

authors： Stalam M,Kaye D

更新日期：2000-06-01 00:00:00

abstract：:Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris-like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus was provided and criti...

journal_title：Infectious disease clinics of North America

authors： Wormser GP,Pritt B

更新日期：2015-06-01 00:00:00

abstract：:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and...

journal_title：Infectious disease clinics of North America

authors： El Chakhtoura NG,Bonomo RA,Jump RLP

更新日期：2017-12-01 00:00:00

abstract：:The incidence of meningococcal disease is at an historic low in the United States, but prevention remains a priority because of the devastating outcomes and risk for outbreaks. Available vaccines are recommended routinely for persons at increased risk for disease to protect against all major serogroups of Neisseria me...

journal_title：Infectious disease clinics of North America

authors： Cohn A,MacNeil J

更新日期：2015-12-01 00:00:00

abstract：:Although a small number of infections in total joint replacements are blood borne from distant sources, most infections appear to have been derived at operation. Strenuous attempts to reduce this risk by cleaning the air in the wound environment, coupled with prophylactic antibiotics, have reduced infection rates by a...

journal_title：Infectious disease clinics of North America

authors： Gillespie WJ

更新日期：1990-09-01 00:00:00

abstract：:HA-1A is a human monoclonal IgM antibody that binds to endotoxin. The results of the clinical trials of HA-1A demonstrate that HA-1A reduces mortality among patients with sepsis and gram-negative bacteremia. Secondary endpoints, including resolution of organ failure, discharge from intensive care unit, and discharge f...

journal_title：Infectious disease clinics of North America

authors： Smith CR,Straube RC,Ziegler EJ

更新日期：1992-03-01 00:00:00

abstract：:The combination of molecular pathogen diagnostics and the biomarker procalcitonin (PCT) are changing the use of antimicrobials in patients admitted to critical care units with severe community-acquired pneumonia, possible septic shock, or other clinical syndromes. An elevated serum PCT level is good supportive evidenc...

journal_title：Infectious disease clinics of North America

authors： Gilbert DN

更新日期：2017-09-01 00:00:00

abstract：:Water serves as a major reservoir for the environmental mycobacteria. Many cases of cutaneous mycobacterial disease result from water exposure. The current theory of the pathogenesis of M. avium complex lung disease involves inhalation of organisms aerosolized from surface water. Disseminated M. avium disease in AIDS ...

journal_title：Infectious disease clinics of North America

authors： Wallace RJ Jr

更新日期：1987-09-01 00:00:00

abstract：:Compromised travelers represent a diverse and challenging group of individuals. They include HIV-infected patients who are at risk for potentially adverse reactions to immunizations, and new exposures to enteric water-borne opportunistic pathogens associated with chronic infections. Such travelers may encounter unfami...

journal_title：Infectious disease clinics of North America

authors： Mileno MD,Bia FJ

更新日期：1998-06-01 00:00:00

abstract：:When properly used, disinfection and sterilization can ensure the safe use of invasive and noninvasive medical devices. The method of disinfection and sterilization depends on the intended use of the medical device: critical items (contact sterile tissue) must be sterilized before use; semicritical items (contact muco...

journal_title：Infectious disease clinics of North America

authors： Rutala WA,Weber DJ

更新日期：2016-09-01 00:00:00

abstract：:Antimicrobial resistance is a natural evolutionary process, which in the case of Mycobacterium tuberculosis is based on spontaneous chromosomal mutations, meaning that well-designed combination drug regimens provided under supervised therapy will prevent the emergence of drug-resistant strains. Unfortunately, limited ...

journal_title：Infectious disease clinics of North America

authors： Kurz SG,Furin JJ,Bark CM

更新日期：2016-06-01 00:00:00

abstract：:This article focuses on the use of immunoglobulin variable regions, including Id, anti-Id, anticlonotypes, and Id engineering as putative vaccines and vaccine strategies for infectious diseases; and specific discussion of Id systems involving antigenic determinants associated with potentially pathogenic organisms. ...

journal_title：Infectious disease clinics of North America

authors： Hefty PS,Kennedy RC

更新日期：1999-03-01 00:00:00

abstract：:The emergence of antimicrobial resistance among several common bacterial pathogens requires that clinical microbiology laboratories have the ability to promptly and accurately recognize resistance in patients' isolates. Laboratories have several options for performing routine susceptibility testing, including the brot...

journal_title：Infectious disease clinics of North America

authors： Jorgensen JH

更新日期：1997-12-01 00:00:00

abstract：:Injection drug use is the most common transmission route for hepatitis C. High rates of infection are observed among individuals on opioid agonist therapy. Although people who inject drugs carry the highest burden, few have initiated treatment. We present a comprehensive review of the evidence on the efficacy of HCV m...

journal_title：Infectious disease clinics of North America

authors： Norton BL,Akiyama MJ,Zamor PJ,Litwin AH

更新日期：2018-06-01 00:00:00

abstract：:Patients with hematologic malignancy or those who undergo hematopoietic stem cell transplantation experience variable degrees of immunosuppression, dependent on underlying disease, therapy received, time since transplant, and complications, such as graft-versus-host disease. Vaccination is an important strategy to mit...

journal_title：Infectious disease clinics of North America

authors： Kamboj M,Shah MK

更新日期：2019-06-01 00:00:00

abstract：:Infectious complications remain a major source of morbidity and mortality for patients with end-stage renal disease on dialysis. The majority of these complications are related to dialysis access devices, and as such represent a potentially modifiable risk factor. This article reviews the important infectious complica...

journal_title：Infectious disease clinics of North America

authors： Bagdasarian N,Heung M,Malani PN

更新日期：2012-03-01 00:00:00

abstract：:The central nervous system and systemic complications of bacterial meningitis cause significant morbidity and mortality. This article offers insight into the clinical features, pathogenesis, and management of these complications. In many instances, the improved outcome of intervention is based on clinical suspicion an...

journal_title：Infectious disease clinics of North America

authors： Rauf SJ,Roberts NJ Jr

更新日期：1999-09-01 00:00:00