HA-1A. A human monoclonal antibody for the treatment of gram-negative sepsis.

abstract：:As the result of a formidable effort, the recent TB epidemic in the United States has abated; however, major questions remain as the risk of TB diminishes. Will we maintain an adequate public health effort not only to prevent another resurgence of TB but also to renew our pursuit of TB elimination? Do we have the will...

journal_title：Infectious disease clinics of North America

authors： Griffith DE

更新日期：1998-09-01 00:00:00

abstract：:Fulminant meningitis requires aggressive management in an intensive care unit setting. The pathophysiology of the various factors that damage the central nervous system in this disease have been reviewed, as well as the management of the many complications of this serious, often devastating, infection. The etiologic a...

journal_title：Infectious disease clinics of North America

authors： Roos KL,Scheld WM

更新日期：1989-03-01 00:00:00

abstract：:Acquired immunodeficiency syndrome (AIDS) is the lethal end stage of a sexually transmitted disease caused by a virus that is producing the major epidemic of our century. In this article we describe the history and epidemiology of AIDS and the disease states associated with infection with the human immunodeficiency vi...

journal_title：Infectious disease clinics of North America

authors： Wood RW,Collier A

更新日期：1987-03-01 00:00:00

abstract：:In the ICU, fever can be expected to accompany an extensive number of conditions of both infectious and noninfectious etiologies. It is crucial to identify the precise cause of fever, because certain conditions in either category may be life-threatening, whereas others require no treatment at all. It is important to r...

journal_title：Infectious disease clinics of North America

authors： Cunha BA,Shea KW

更新日期：1996-03-01 00:00:00

abstract：:An increasing number of HIV-infected patients will require surgical therapy. The methods of diagnosis and therapeutic planning for HIV-infected patients are the same as for all other patients. Surgery should be advised if an operation is likely to have a positive effect on the patient's life. Most patients with AIDS w...

journal_title：Infectious disease clinics of North America

authors： Macho JR,Schecter WP

更新日期：1992-09-01 00:00:00

abstract：:Use of the most rapid and reliable laboratory tests for mycobacterial detection, identification, and susceptibility testing is important for TB control. In 1993, CDC experts made recommendations regarding optimal methods of mycobacterial testing (i.e., stains for AFB, culture, identification, and susceptibility testin...

journal_title：Infectious disease clinics of North America

authors： Woods GL

更新日期：2002-03-01 00:00:00

abstract：:CSF evaluation is the single most important aspect of the laboratory diagnosis of meningitis. Analysis of the CSF abnormalities produced by bacterial, mycobacterial, and fungal infections may greatly facilitate diagnosis and direct initial therapy. Basic studies of CSF that should be performed in all patients with men...

journal_title：Infectious disease clinics of North America

authors： Greenlee JE

更新日期：1990-12-01 00:00:00

abstract：:This article establishes the pharmacokinetic-pharmacodynamic parameters that are important when considering the intracellular activity of antibiotics. Generally speaking, the main classes of antibiotics seem to share globally the same properties against extracellular and intracellular organisms. The specific cellular ...

journal_title：Infectious disease clinics of North America

authors： Carryn S,Chanteux H,Seral C,Mingeot-Leclercq MP,Van Bambeke F,Tulkens PM

更新日期：2003-09-01 00:00:00

abstract：:Acute bacterial endocarditis (ABE) is clinically distinct from subacute bacterial endocarditis in terms of pathologic virulence, acuteness and severity of illness, complications, and prognosis. The term infectious endocarditis may be useful as a general term but conveys no meaningful clinical information. ABE presents...

journal_title：Infectious disease clinics of North America

authors： Cunha BA,Gill MV,Lazar JM

更新日期：1996-12-01 00:00:00

abstract：:This article reviews the changing epidemiology of infections associated with injection drug use, perceived barriers to care, features of successful programs for outpatient antimicrobial treatment, models of shared decision making at the time of discharge, and linkage to preventative care after antimicrobial completion...

journal_title：Infectious disease clinics of North America

authors： Hurley H,Sikka M,Jenkins T,Cari EV,Thornton A

更新日期：2020-09-01 00:00:00

abstract：:Emerging tick-borne infections continue to be observed in the United States and elsewhere. Current information on the epidemiology, clinical and laboratory features, and treatment of infections due to Ehrlichia muris-like agent, deer tick virus, Borrelia miyamotoi sensu lato, and Heartland virus was provided and criti...

journal_title：Infectious disease clinics of North America

authors： Wormser GP,Pritt B

更新日期：2015-06-01 00:00:00

abstract：:The problem of prophylaxis in orthopedic implant surgery will become increasingly important and complex as the population ages and requires more arthroplasty procedures, and the prevalence of antimicrobial-resistant bacteria meanwhile also continues to rise. Energy spent preventing prosthetic joint infection is more e...

journal_title：Infectious disease clinics of North America

authors： Marculescu CE,Osmon DR

更新日期：2005-12-01 00:00:00

abstract：:This article presents a discussion of the management of vascular prosthetic infections. The emphasis is on aortic graft infections, but other peripheral graft infections are also discussed. ...

journal_title：Infectious disease clinics of North America

authors： Golan JF

更新日期：1989-06-01 00:00:00

abstract：:Within the past several years, the decision to employ outpatient parenteral antibiotic therapy (OPAT) is driven by adequacy of insurance, availability of appropriate resources within the community, and the clinical stability of the patient. Current dogma is that virtually any diagnosed disease can be treated outside t...

journal_title：Infectious disease clinics of North America

authors： Brown RB

更新日期：1998-12-01 00:00:00

abstract：:The unknowns persisting in the understanding of the mode of action of anti-core lipopolysaccharide antibodies are discussed, and a study of two anti-lipid A monoclonal antibodies is reviewed. This article also critically analyzes the results of the recent clinical trials with monoclonal antibodies. ...

journal_title：Infectious disease clinics of North America

authors： Baumgartner JD

更新日期：1991-12-01 00:00:00

abstract：:Mass gatherings have attracted the attention of the medical community because of the increased demand made on existing services and the potential for public health problems resulting from changes in population dynamics and behaviors. Crowding, lack of hygiene, and rapid population movement at mass gatherings can lead ...

journal_title：Infectious disease clinics of North America

authors： Al-Tawfiq JA,Memish ZA

更新日期：2012-09-01 00:00:00

abstract：:Vaccine recommendations continue to evolve as a result of new vaccines, safety considerations, changing disease incidence (e.g., polio), and public health priorities. The pace of discovery is accelerating and advisory committees will need to respond accordingly. Each vaccine, new or old, will be required to earn its p...

journal_title：Infectious disease clinics of North America

authors： Gardner P,Peter G

更新日期：2001-03-01 00:00:00

abstract：:Recent decades have witnessed the emergence and spread of parasites resistant to standard drug therapies, particularly malaria. Chloroquine-resistant Plasmodium falciparum has now spread to most malarial areas, and resistance to other antimalarial drugs, including mefloquine and sulfadoxine-pyrimethamine, have become ...

journal_title：Infectious disease clinics of North America

authors： Barat LM,Bloland PB

更新日期：1997-12-01 00:00:00

abstract：:Bioterrorism preparedness is clearly a goal for the health care community, working in concert with city, county, state, and federal public health and emergency authorities and in collaboration with law enforcement at the local and federal levels. Opening the channels of communication between all groups involved, obtai...

journal_title：Infectious disease clinics of North America

authors： Miller JM

更新日期：2001-12-01 00:00:00

abstract：:Reactive arthritis is classified as a spondyloarthropathy. Current concepts of disease suggest an infectious trigger, followed by inflammatory arthritis. Several mechanisms have been proposed to explain the interaction of host susceptibility and microorganism. Diagnosis relies on a compatible clinical syndrome and mic...

journal_title：Infectious disease clinics of North America

authors： Schmitt SK

更新日期：2017-06-01 00:00:00

abstract：:Although antibiotic therapy is the mainstay of therapy for gram-negative bacillary bacteremia, the amelioration of the underlying conditions, the correction of predisposing factors, the drainage of abscesses, the removal of infected foreign bodies, and adequate supportive care are also of paramount importance for curi...

journal_title：Infectious disease clinics of North America

authors： Calandra T,Cometta A

更新日期：1991-12-01 00:00:00

abstract：:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and...

journal_title：Infectious disease clinics of North America

authors： El Chakhtoura NG,Bonomo RA,Jump RLP

更新日期：2017-12-01 00:00:00

abstract：:This article reviews in brief the basic principles of echocardiography and their application in infective endocarditis. The role of echocardiography in relation to surgical decision making is emphasized. The special problems of vegetations, valve ring abscess, leaflet perforation, prosthetic valve endocarditis, and in...

journal_title：Infectious disease clinics of North America

authors： Murphy JG,Foster-Smith K

更新日期：1993-03-01 00:00:00

abstract：:This article discusses two tick-borne illnesses: Powassan encephalitis, a rare cause of central nervous system infection caused by the Powassan virus, and Colorado tick fever, an acute febrile illness caused by the Colorado tick fever virus common to the Rocky Mountain region of North America. ...

journal_title：Infectious disease clinics of North America

authors： Romero JR,Simonsen KA

更新日期：2008-09-01 00:00:00

abstract：:Recurrent urinary tract infections (UTIs) are common, especially in women. Low-dose daily or postcoital antimicrobial prophylaxis is effective for prevention of recurrent UTIs and women can self-diagnose and self-treat a new UTI with antibiotics. The increasing resistance rates of Escherichia coli to antimicrobial age...

journal_title：Infectious disease clinics of North America

authors： Geerlings SE,Beerepoot MA,Prins JM

更新日期：2014-03-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over ...

journal_title：Infectious disease clinics of North America

authors： Restrepo MI,Anzueto A

更新日期：2009-09-01 00:00:00

abstract：:The diagnostic approach to the compromised host with CNS infection depends on an analysis of the patient's clinical manifestations of CNS disease, the acuteness or subacuteness of the clinical presentation, and an analysis of the type of immune defect compromising the patient's host defenses. Most patients with CNS in...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:The identification of characteristic clinical, serologic, and immunologic responses to primary HIV infection has contributed greatly to our understanding of the natural history of HIV infection. Subjects usually present with a mononucleosis-like illness and during the period of primary infection there is a characteris...

journal_title：Infectious disease clinics of North America

authors： Tindall B,Cooper DA,Donovan B,Penny R

更新日期：1988-06-01 00:00:00

abstract：:A wide range of soft-tissue infections can occur in diabetic patients, the consequences of which can be devastating. Early recognition and intervention, which may involve both surgical and medical approaches, can improve clinical outcomes. ...

journal_title：Infectious disease clinics of North America

authors： Sentochnik DE

更新日期：1995-03-01 00:00:00

abstract：:Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of t...

journal_title：Infectious disease clinics of North America

authors： Collin BA,Ramphal R

更新日期：1998-09-01 00:00:00