Influence of Aging and Environment on Presentation of Infection in Older Adults.

Abstract:

:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and frailty. We also describe clinical factors influencing infection risk and presentation in older adults, including temperature regulation, cognitive decline, and malnutrition. Finally, we discuss the influence of the setting in which older adults reside on the clinical evaluation of infection. Understanding the influence of all these changes may facilitate the prevention, early recognition, and treatment of infections in older adults.

authors

El Chakhtoura NG,Bonomo RA,Jump RLP

doi

10.1016/j.idc.2017.07.017

subject

Has Abstract

pub_date

2017-12-01 00:00:00

pages

593-608

issue

4

eissn

0891-5520

issn

1557-9824

pii

S0891-5520(17)30071-5

journal_volume

31

pub_type

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