Abstract:
:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and frailty. We also describe clinical factors influencing infection risk and presentation in older adults, including temperature regulation, cognitive decline, and malnutrition. Finally, we discuss the influence of the setting in which older adults reside on the clinical evaluation of infection. Understanding the influence of all these changes may facilitate the prevention, early recognition, and treatment of infections in older adults.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
El Chakhtoura NG,Bonomo RA,Jump RLPdoi
10.1016/j.idc.2017.07.017subject
Has Abstractpub_date
2017-12-01 00:00:00pages
593-608issue
4eissn
0891-5520issn
1557-9824pii
S0891-5520(17)30071-5journal_volume
31pub_type
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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pub_type: 杂志文章,评审
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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