Bloodborne pathogen transmission in health care workers. Risks and prevention strategies.

abstract：:Population growth in the twentieth century is at its highest level in history, with the world's population now doubling in approximately 40 years. An unprecedented 90 million people are being added worldwide each year, with most of the growth taking place in the developing world. The implications of this rate of growt...

journal_title：Infectious disease clinics of North America

authors： Rosenfield A

更新日期：1991-06-01 00:00:00

abstract：:Antiviral agents aimed at treating HSV-2 chronically infected individuals have proven to be effective in the prevention of symptomatic genital herpes and the reduction of viral shedding. These agents play a key role in current HIV prevention trials that will assess the role of suppression of HSV-2 infection on the ris...

journal_title：Infectious disease clinics of North America

authors： Reynolds SJ,Quinn TC

更新日期：2005-06-01 00:00:00

abstract：:At the heart of imminent healthcare reform are the future physicians of this decade. Medical educators will want to stimulate a desire within students to practice humanitarian, cost-effective, community-oriented primary care. Further studies to examine the effects of medical student experiences in international electi...

journal_title：Infectious disease clinics of North America

authors： Chiller TM,De Mieri P,Cohen I

更新日期：1995-06-01 00:00:00

abstract：:Changes that occur in the pharmacology of drugs in the elderly must be considered in the use of antimicrobial agents. Although absorption of orally administered drugs is not affected in a significant way, renal function decreases, drug-drug interactions increase, compliance with regimens may be decreased, and drug tox...

journal_title：Infectious disease clinics of North America

authors： Stalam M,Kaye D

更新日期：2000-06-01 00:00:00

abstract：:Antigens located in the midgut of the tick are hidden from the host's immune system. Egg production of ticks can be reduced when ticks are fed on animals vaccinated with midgut antigens of the tick, and a subunit vaccine formulated with the recombinant antigen Bm86 is now available that can reduce the number of ticks ...

journal_title：Infectious disease clinics of North America

authors： Lee R,Opdebeeck JP

更新日期：1999-03-01 00:00:00

abstract：:Improvements in donor selection, testing of donors for markers of infection, and viral inactivation of plasma-derived products have helped reduce the risk of transfusion-associated infections, including hepatitis B (HBV), hepatitis C (HCV), and human immunodeficiency viruses (HIV). The potential for transmission of em...

journal_title：Infectious disease clinics of North America

authors： Chamberland M,Khabbaz RF

更新日期：1998-03-01 00:00:00

abstract：:Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of t...

journal_title：Infectious disease clinics of North America

authors： Collin BA,Ramphal R

更新日期：1998-09-01 00:00:00

abstract：:Campylobacter is now known to be a major cause of gastrointestinal illness throughout the world. There are seven species known to be associated with enteritis, and it is likely that more will be described. Campylobacter jejuni is responsible for more than 95 per cent of the cases of diarrhea due to Campylobacter. Cont...

journal_title：Infectious disease clinics of North America

authors： Cornick NA,Gorbach SL

更新日期：1988-09-01 00:00:00

abstract：:Animal models have proven to be invaluable in bridging the gap between in vitro susceptibility testing of an antibiotic and anticipating results obtained in clinical studies. Variables such as antibiotic concentration, inoculum of organism, and pharmacokinetic parameters of the drug can be carefully controlled to prov...

journal_title：Infectious disease clinics of North America

authors： Tunkel AR,Scheld WM

更新日期：1989-09-01 00:00:00

abstract：:It appears incontestable that there is a link between genital ulcer disease and HIV infection. On the one hand the natural history and response to therapy of syphilis, HSV-2, and chancroid are all modified by the immunosuppressive effects of HIV infection. On the other hand, HIV transmission is probably facilitated by...

journal_title：Infectious disease clinics of North America

authors： Augenbraun MH,McCormack WM

更新日期：1994-06-01 00:00:00

abstract：:Amebiasis is a widespread parasitic disease caused by Entamoeba histolytica. This protozoan organism is the third leading parasitic cause of death in the developing world and is an important health risk to travelers in endemic areas. Amebiasis most commonly results in asymptomatic colonization of the gastrointestinal ...

journal_title：Infectious disease clinics of North America

authors： Hughes MA,Petri WA Jr

更新日期：2000-09-01 00:00:00

abstract：:Cytomegalovirus (CMV) continues to be responsible for a substantial fraction of the morbidity and mortality that follows organ transplantation. The three major consequences of CMV infection are CMV disease (encompassing a range of clinical illness), superinfection with opportunistic pathogens, and injury to the transp...

journal_title：Infectious disease clinics of North America

authors： Hibberd PL,Snydman DR

更新日期：1995-12-01 00:00:00

abstract：:A small number of bacterial agents, including enterotoxigenic Escherichia coli (ETEC), enteropathogenic E. coli (EPEC), Shigella and Vibrio cholerae 01 and one virus, rotavirus, combine to cause a major proportion of the diarrheal illness of public health importance worldwide. Salmonella typhi is by far the major caus...

journal_title：Infectious disease clinics of North America

authors： Levine MM,Edelman R

更新日期：1990-03-01 00:00:00

abstract：:Infections accompanying severe pancreatitis are secondary and of three types: infected pancreatic necrosis, infected pseudocyst (including peripancreatic fluid collection), and pancreatic abscess. The first is an earlier, more morbid process, with antibiotics supportive and surgical debridement necessary. The latter t...

journal_title：Infectious disease clinics of North America

authors： Traverso LW

更新日期：1992-09-01 00:00:00

abstract：:Mold infections carry a substantial clinical and economic burden in solid organ transplant (SOT) recipients with a high overall mortality of near 30%. The most important pathogens include Aspergillus, the Zygomycetes, Fusarium, Scedosporium/Pseudallescheria, and the dematiaceous (dark) molds. Risk factors for the infe...

journal_title：Infectious disease clinics of North America

authors： Lemonovich TL

更新日期：2018-09-01 00:00:00

abstract：:The number of species that comprise the family of Bartonellaceae, genus Bartonella, has recently increased from one to 11 species, five of which have been associated with different diseases and syndromes in humans. The rapidly growing number of human pathogens has led several investigators to regard bartonellosis and ...

journal_title：Infectious disease clinics of North America

authors： Maguiña C,Gotuzzo E

更新日期：2000-03-01 00:00:00

abstract：:Staphylococcus aureus is an important pathogen in the hospital and in the community, and it is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S aureus is needed. The most extensively tested vaccine against S aureus, which is a capsular polysaccharide-based vaccine known as S...

journal_title：Infectious disease clinics of North America

authors： Schaffer AC,Lee JC

更新日期：2009-03-01 00:00:00

abstract：:Mass gatherings have attracted the attention of the medical community because of the increased demand made on existing services and the potential for public health problems resulting from changes in population dynamics and behaviors. Crowding, lack of hygiene, and rapid population movement at mass gatherings can lead ...

journal_title：Infectious disease clinics of North America

authors： Al-Tawfiq JA,Memish ZA

更新日期：2012-09-01 00:00:00

abstract：:Infection with HIV is a problem of growing magnitude among women and children in the United States. During 1991, AIDS will be among the five leading causes of death for women of childbearing age. Over 80% of children with HIV have acquired the infection vertically, and AIDS is now a leading cause of death of children ...

journal_title：Infectious disease clinics of North America

authors： Kline MW,Shearer WT

更新日期：1992-03-01 00:00:00

abstract：:Catheter-related bloodstream infections (CRBSI) are responsible for significant morbidity, mortality, and excess health care costs. It is increasingly evident that many CRBSI can be prevented with current knowledge and techniques. Preventive measures can be broadly grouped into clinical practice-based interventions an...

journal_title：Infectious disease clinics of North America

authors： Rupp ME,Majorant D

更新日期：2016-12-01 00:00:00

abstract：:Viral hepatitis is a major global public health problem affecting hundreds of millions of people and is associated with significant morbidity and mortality. Five major biologically unrelated hepatotropic viruses cause most of the global burden of viral hepatitis. Hepatitis B and hepatitis C are associated with a signi...

journal_title：Infectious disease clinics of North America

authors： Lanini S,Ustianowski A,Pisapia R,Zumla A,Ippolito G

更新日期：2019-12-01 00:00:00

abstract：:Genome-wide association studies have identified polymorphisms located near the gene encoding IL28B, which turned out to be the best predictor of response to pegylated interferon plus ribavirin for chronic hepatitis C virus (HCV) genotype 1 infection. This association was extended to spontaneous clearance of HCV, sugge...

journal_title：Infectious disease clinics of North America

authors： Berger CT,Kim AY

更新日期：2012-12-01 00:00:00

abstract：:An ever-increasing population of immunocompromised individuals, including not only the burgeoning AIDS population but also those patients whose host defenses have been damaged by a wide variety of diseases and their therapies, requires prophylaxis against infectious diseases. Existing vaccines can provide some benefit...

journal_title：Infectious disease clinics of North America

authors： Hibberd PL,Rubin RH

更新日期：1990-03-01 00:00:00

abstract：:The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria. This article reviews the role of CD14,...

journal_title：Infectious disease clinics of North America

authors： Ingalls RR,Heine H,Lien E,Yoshimura A,Golenbock D

更新日期：1999-06-01 00:00:00

abstract：:The returning traveler with fever presents a diagnostic challenge for the health care provider. When evaluating such a patient, the highest priority should be given to diseases that are potentially fatal or may represent public health threats. A good history is paramount and needs to include destination, time and dura...

journal_title：Infectious disease clinics of North America

authors： Speil C,Mushtaq A,Adamski A,Khardori N

更新日期：2007-12-01 00:00:00

abstract：:Septic shock is a common life-threatening problem, usually presenting with fever, tachycardia, tachypnea, and often a source of infection. The cardiac index is increased, with a decreased systemic vascular resistance, and a reversibly decreased ejection fraction with an increased end diastolic volume. The myocardial d...

journal_title：Infectious disease clinics of North America

authors： Toney JF,Parker MM

更新日期：1996-06-01 00:00:00

abstract：:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and...

journal_title：Infectious disease clinics of North America

authors： El Chakhtoura NG,Bonomo RA,Jump RLP

更新日期：2017-12-01 00:00:00

abstract：:This article presents a discussion of the management of vascular prosthetic infections. The emphasis is on aortic graft infections, but other peripheral graft infections are also discussed. ...

journal_title：Infectious disease clinics of North America

authors： Golan JF

更新日期：1989-06-01 00:00:00

abstract：:Influenza is a zoonotic respiratory virus that affects birds, mammals, and humans. Influenza viruses are unique in their genetic instability, which frequently results in antigenic drift or shift. Antigenic shifts are responsible for influenza epidemics. Influenza A pandemics have been responsible for millions of death...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2004-03-01 00:00:00

abstract：:Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. It accounts for 500,000 hospitalizations and 45,000 deaths each year, and it represents one of the most common causes of ICU admission. The mortality rate due to severe CAP has shown little improvement over ...

journal_title：Infectious disease clinics of North America

authors： Restrepo MI,Anzueto A

更新日期：2009-09-01 00:00:00