Mold Infections in Solid Organ Transplant Recipients.

Abstract:

:Mold infections carry a substantial clinical and economic burden in solid organ transplant (SOT) recipients with a high overall mortality of near 30%. The most important pathogens include Aspergillus, the Zygomycetes, Fusarium, Scedosporium/Pseudallescheria, and the dematiaceous (dark) molds. Risk factors for the infections vary by transplant type but include degree of immune suppression and loss of skin or mucosal integrity. Correct diagnosis usually requires histopathology and/or culture. Management often requires a multidisciplinary team approach with combined antifungal and surgical therapies. This article reviews the epidemiology, risk factors, microbiology, diagnostic, and treatment approach to mold infections in SOT recipients.

authors

Lemonovich TL

doi

10.1016/j.idc.2018.04.006

subject

Has Abstract

pub_date

2018-09-01 00:00:00

pages

687-701

issue

3

eissn

0891-5520

issn

1557-9824

pii

S0891-5520(18)30041-2

journal_volume

32

pub_type

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