Pharmacologic issues of antiretroviral agents and immunosuppressive regimens in HIV-infected solid organ transplant recipients.

abstract：:No practitioner can hide from HIV. Patients infected with HIV are treated in every type of practice setting as the number of cases increases at an alarming rate. This article provides 10 basic guidelines for the care of HIV-infected patients. ...

journal_title：Infectious disease clinics of North America

authors： Glatt AE

更新日期：1994-06-01 00:00:00

abstract：:Septic arthritis still continues to be a common and serious problem at major urban medical centers and is one of the most rapidly destructive forms of acute arthritis. The yearly incidence of bacterial arthritis varies from 2 to 10 per 100,000 in the general population to 30 to 70 per 100,000 in patients with rheumato...

journal_title：Infectious disease clinics of North America

authors： García-De La Torre I

更新日期：2006-12-01 00:00:00

abstract：:Catheter-related bloodstream infections (CRBSI) are responsible for significant morbidity, mortality, and excess health care costs. It is increasingly evident that many CRBSI can be prevented with current knowledge and techniques. Preventive measures can be broadly grouped into clinical practice-based interventions an...

journal_title：Infectious disease clinics of North America

authors： Rupp ME,Majorant D

更新日期：2016-12-01 00:00:00

abstract：:Ultrasound for diagnosis and staging of schistosomiasis and echinococcosis have paved the way over the past several decades for the application of ultrasound in tropical diseases. Until recently, the size and cost of ultrasound systems limited the application in low-resource settings. The increase in portable ultrasou...

journal_title：Infectious disease clinics of North America

authors： Kaminstein D,Heller T,Tamarozzi F

更新日期：2019-03-01 00:00:00

abstract：:HIV and tropical infections affect each other mutually. HIV infection may alter the natural history of tropical infectious diseases, impede rapid diagnosis, or reduce the efficacy of antiparasitic treatment. Tropical infections may facilitate the transmission of HIV and accelerate progression from asymptomatic HIV inf...

journal_title：Infectious disease clinics of North America

authors： Harms G,Feldmeier H

更新日期：2005-03-01 00:00:00

abstract：:Nosocomial diarrhea due to infection with C. difficile is a major health care problem, causing 20% to 30% of institutionally acquired diarrhea and affecting up to 8% of hospitalized patients. The clinical microbiology laboratory should be able to provide both diagnostic and epidemiologic services for institutions wher...

journal_title：Infectious disease clinics of North America

authors： Peterson LR,Kelly PJ

更新日期：1993-06-01 00:00:00

abstract：:Vancomycin and daptomycin are options for the initial treatment of patients with methicillin-resistant Staphylococcus aureus (MRSA) bacteremia. Treatment options for persistent MRSA bacteremia or bacteremia due to vancomycin-intermediate or vancomycin-resistant strains include daptomycin, ceftaroline, and combination ...

journal_title：Infectious disease clinics of North America

authors： Holubar M,Meng L,Alegria W,Deresinski S

更新日期：2020-12-01 00:00:00

abstract：:Animal models have proven to be invaluable in bridging the gap between in vitro susceptibility testing of an antibiotic and anticipating results obtained in clinical studies. Variables such as antibiotic concentration, inoculum of organism, and pharmacokinetic parameters of the drug can be carefully controlled to prov...

journal_title：Infectious disease clinics of North America

authors： Tunkel AR,Scheld WM

更新日期：1989-09-01 00:00:00

abstract：:Staphylococcus aureus is a leading cause of bacteremia and endocarditis. Over the past several years, the frequency of S. aureus bacteremia (SAB) has increased dramatically. This increasing frequency, coupled with increasing rates of antibiotic resistance, has renewed interest in this serious, common infection. S. aur...

journal_title：Infectious disease clinics of North America

authors： Petti CA,Fowler VG Jr

更新日期：2002-06-01 00:00:00

abstract：:The emergence of resistance to antimicrobial agents continues to be a major problem among both nosocomial and community-acquired pathogens. Bacteria employ a variety of strategies to avoid the inhibitory effects of antibiotic agents, and have evolved highly efficient means for the dissemination of resistance traits. T...

journal_title：Infectious disease clinics of North America

authors： Fraimow HS,Abrutyn E

更新日期：1995-09-01 00:00:00

abstract：:Although infective endocarditis is certainly not the most common infection seen in injecting drug users, it is the infection that clinicians most commonly think of when they consider infectious complications of injected drug use. The microbiology of infective endocarditis in injection drug users has remained relativel...

journal_title：Infectious disease clinics of North America

authors： Brown PD,Levine DP

更新日期：2002-09-01 00:00:00

abstract：:The viral hemorrhagic fever (VHF) syndrome is a potentially life-threatening infection typified by a combination of a capillary leak syndrome and bleeding diathesis. Most but not all agents causing VHF are arboviruses, with transmission to humans resulting from an arthropod bite. Agents of VHF affect humans on all con...

journal_title：Infectious disease clinics of North America

authors： Meltzer E

更新日期：2012-06-01 00:00:00

abstract：:A wide range of soft-tissue infections can occur in diabetic patients, the consequences of which can be devastating. Early recognition and intervention, which may involve both surgical and medical approaches, can improve clinical outcomes. ...

journal_title：Infectious disease clinics of North America

authors： Sentochnik DE

更新日期：1995-03-01 00:00:00

abstract：:The emergence of antimicrobial resistance among several common bacterial pathogens requires that clinical microbiology laboratories have the ability to promptly and accurately recognize resistance in patients' isolates. Laboratories have several options for performing routine susceptibility testing, including the brot...

journal_title：Infectious disease clinics of North America

authors： Jorgensen JH

更新日期：1997-12-01 00:00:00

abstract：:It appears incontestable that there is a link between genital ulcer disease and HIV infection. On the one hand the natural history and response to therapy of syphilis, HSV-2, and chancroid are all modified by the immunosuppressive effects of HIV infection. On the other hand, HIV transmission is probably facilitated by...

journal_title：Infectious disease clinics of North America

authors： Augenbraun MH,McCormack WM

更新日期：1994-06-01 00:00:00

abstract：:HIV testing and incidence are stable, but trends for certain populations are concerning. Primary prevention must be reinvigorated and target vulnerable populations. Science and policy have progressed to improve the accuracy, speed, privacy, and affordability of HIV testing. More potent and much better tolerated HIV tr...

journal_title：Infectious disease clinics of North America

authors： Rodriguez CV,Horberg MA

更新日期：2014-09-01 00:00:00

abstract：:Various nontuberculous mycobacteria can cause infection of skin and soft tissues. These organisms are also known as atypical mycobacteria, anonymous mycobacteria, and mycobacteria other than tuberculosis. These organisms are much more common causes of cutaneous infection than Mycobacterium tuberculosis. Infections cau...

journal_title：Infectious disease clinics of North America

authors： Dalovisio JR,Pankey GA

更新日期：1994-09-01 00:00:00

abstract：:The diagnostic approach to the compromised host with CNS infection depends on an analysis of the patient's clinical manifestations of CNS disease, the acuteness or subacuteness of the clinical presentation, and an analysis of the type of immune defect compromising the patient's host defenses. Most patients with CNS in...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:Successful antimicrobial stewardship programs rely on engagement with hospital administrators. Antimicrobial stewards should understand the unique pressures and demands of hospital and health system administration and be familiar with key terminology and regulatory requirements. This article provides guidance on strat...

journal_title：Infectious disease clinics of North America

authors： Buckel WR,Kaye KS,Patel PK

更新日期：2020-03-01 00:00:00

abstract：:Staphylococcus aureus is an important pathogen in the hospital and in the community, and it is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S aureus is needed. The most extensively tested vaccine against S aureus, which is a capsular polysaccharide-based vaccine known as S...

journal_title：Infectious disease clinics of North America

authors： Schaffer AC,Lee JC

更新日期：2009-03-01 00:00:00

abstract：:In healthy adults and children in developed countries, most foodborne and water-borne infections are short-lived and resolve without specific treatment. In developing areas, these infections may produce acute mortality and chronic morbidity caused by developmental impairment. Immune-compromised hosts are at increased ...

journal_title：Infectious disease clinics of North America

authors： Steiner T

更新日期：2013-09-01 00:00:00

abstract：:At the close of the 19th century, the germ theory had generated a new understanding of the causes of acute infectious diseases and revealed new directions for study. This understanding contributed to the greatest improvements in health in the history of medicine. At the end of the 20th century, the second stage of thi...

journal_title：Infectious disease clinics of North America

authors： Ewald PW

更新日期：2004-03-01 00:00:00

abstract：:Coccidioides, a fungus, is endemic to specific parts of the Western Hemisphere. This article examines the prevalence, pathogenesis and host defense, clinical manifestations, diagnosis, and treatment of coccidioidomycosis. ...

journal_title：Infectious disease clinics of North America

authors： Chiller TM,Galgiani JN,Stevens DA

更新日期：2003-03-01 00:00:00

abstract：:Histoplasmosis is a fungus disease of nearly worldwide distribution. Because of its wide distribution and tendency to be endemic near large cities, it is the most common systemic mycosis in the United States, with an estimated 500,000 new infections per year. Although millions of persons in the United States have been...

journal_title：Infectious disease clinics of North America

authors： Wheat LJ

更新日期：1988-12-01 00:00:00

abstract：:Bioterrorism preparedness is clearly a goal for the health care community, working in concert with city, county, state, and federal public health and emergency authorities and in collaboration with law enforcement at the local and federal levels. Opening the channels of communication between all groups involved, obtai...

journal_title：Infectious disease clinics of North America

authors： Miller JM

更新日期：2001-12-01 00:00:00

abstract：:Bronchiolitis is a lower respiratory tract illness caused by viral infection in children 2 years of age and younger, frequently associated with wheezing on physical examination. It is a common cause of hospitalization, particularly in patients with risk factors for more serious disease. The diagnosis can be made based...

journal_title：Infectious disease clinics of North America

authors： Kyler KE,McCulloh RJ

更新日期：2018-03-01 00:00:00

abstract：:Antimicrobial resistance is a natural evolutionary process, which in the case of Mycobacterium tuberculosis is based on spontaneous chromosomal mutations, meaning that well-designed combination drug regimens provided under supervised therapy will prevent the emergence of drug-resistant strains. Unfortunately, limited ...

journal_title：Infectious disease clinics of North America

authors： Kurz SG,Furin JJ,Bark CM

更新日期：2016-06-01 00:00:00

abstract：:Serum protein binding of antimicrobials can reduce antimicrobial activity, restrict tissue distribution, and delay drug elimination. Binding percentages of 80 per cent or more have the potential to significantly reduce free drug levels and affect therapeutic efficacy in patients. However, binding-induced alterations i...

journal_title：Infectious disease clinics of North America

authors： Craig WA,Ebert SC

更新日期：1989-09-01 00:00:00

abstract：:Mass gatherings have attracted the attention of the medical community because of the increased demand made on existing services and the potential for public health problems resulting from changes in population dynamics and behaviors. Crowding, lack of hygiene, and rapid population movement at mass gatherings can lead ...

journal_title：Infectious disease clinics of North America

authors： Al-Tawfiq JA,Memish ZA

更新日期：2012-09-01 00:00:00

abstract：:Recent decades have witnessed the emergence and spread of parasites resistant to standard drug therapies, particularly malaria. Chloroquine-resistant Plasmodium falciparum has now spread to most malarial areas, and resistance to other antimalarial drugs, including mefloquine and sulfadoxine-pyrimethamine, have become ...

journal_title：Infectious disease clinics of North America

authors： Barat LM,Bloland PB

更新日期：1997-12-01 00:00:00