Deep soft-tissue infections in diabetic patients.

abstract：:Acquired immunodeficiency syndrome (AIDS) is the lethal end stage of a sexually transmitted disease caused by a virus that is producing the major epidemic of our century. In this article we describe the history and epidemiology of AIDS and the disease states associated with infection with the human immunodeficiency vi...

journal_title：Infectious disease clinics of North America

authors： Wood RW,Collier A

更新日期：1987-03-01 00:00:00

abstract：:Although antimicrobial stewardship has been shown to improve microbiologic susceptibility patterns, decrease drug toxicities, and lower overall drug costs in the inpatient setting, there are few studies assessing programs in the long-term care (LTC) setting. Implementing antimicrobial stewardship programs in LTC setti...

journal_title：Infectious disease clinics of North America

authors： Rhee SM,Stone ND

更新日期：2014-06-01 00:00:00

abstract：:Since the beginning of the epidemic, extensive research has been conducted in the field of HIV infection. Original research and subsequent meta-analyses have contributed to a better understanding of the disease. Epidemiologic research has shown, for example, that male circumcision reduces the risk of female-to-male tr...

journal_title：Infectious disease clinics of North America

authors： Vergidis PI,Falagas ME,Hamer DH

更新日期：2009-06-01 00:00:00

abstract：:Changes that occur in the pharmacology of drugs in the elderly must be considered in the use of antimicrobial agents. Although absorption of orally administered drugs is not affected in a significant way, renal function decreases, drug-drug interactions increase, compliance with regimens may be decreased, and drug tox...

journal_title：Infectious disease clinics of North America

authors： Stalam M,Kaye D

更新日期：2000-06-01 00:00:00

abstract：:Staphylococcus aureus is an important pathogen in the hospital and in the community, and it is increasingly resistant to multiple antibiotics. A nonantimicrobial approach to controlling S aureus is needed. The most extensively tested vaccine against S aureus, which is a capsular polysaccharide-based vaccine known as S...

journal_title：Infectious disease clinics of North America

authors： Schaffer AC,Lee JC

更新日期：2009-03-01 00:00:00

abstract：:As the result of a formidable effort, the recent TB epidemic in the United States has abated; however, major questions remain as the risk of TB diminishes. Will we maintain an adequate public health effort not only to prevent another resurgence of TB but also to renew our pursuit of TB elimination? Do we have the will...

journal_title：Infectious disease clinics of North America

authors： Griffith DE

更新日期：1998-09-01 00:00:00

abstract：:Global eradication of smallpox, elimination of poliomyelitis in the Western Hemisphere, and a 90% decrease in Haemophilus influenzae meningitis in the Western Hemisphere mark some of the achievements of immunization programs around the world. Yet many serious problems continue to exist, particularly in the developing ...

journal_title：Infectious disease clinics of North America

authors： Grossman M

更新日期：1995-06-01 00:00:00

abstract：:Acute bacterial endocarditis (ABE) is clinically distinct from subacute bacterial endocarditis in terms of pathologic virulence, acuteness and severity of illness, complications, and prognosis. The term infectious endocarditis may be useful as a general term but conveys no meaningful clinical information. ABE presents...

journal_title：Infectious disease clinics of North America

authors： Cunha BA,Gill MV,Lazar JM

更新日期：1996-12-01 00:00:00

abstract：:Serum protein binding of antimicrobials can reduce antimicrobial activity, restrict tissue distribution, and delay drug elimination. Binding percentages of 80 per cent or more have the potential to significantly reduce free drug levels and affect therapeutic efficacy in patients. However, binding-induced alterations i...

journal_title：Infectious disease clinics of North America

authors： Craig WA,Ebert SC

更新日期：1989-09-01 00:00:00

abstract：:Infection is a well-described complication of cirrhosis and is a major cause of death in this population. This article examines the types of infections related with cirrhosis, such as bacteremia, urinary tract infections, meningitis, and others. ...

journal_title：Infectious disease clinics of North America

authors： Johnson DH,Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:Patients with hematologic malignancy or those who undergo hematopoietic stem cell transplantation experience variable degrees of immunosuppression, dependent on underlying disease, therapy received, time since transplant, and complications, such as graft-versus-host disease. Vaccination is an important strategy to mit...

journal_title：Infectious disease clinics of North America

authors： Kamboj M,Shah MK

更新日期：2019-06-01 00:00:00

abstract：:Fulminant meningitis requires aggressive management in an intensive care unit setting. The pathophysiology of the various factors that damage the central nervous system in this disease have been reviewed, as well as the management of the many complications of this serious, often devastating, infection. The etiologic a...

journal_title：Infectious disease clinics of North America

authors： Roos KL,Scheld WM

更新日期：1989-03-01 00:00:00

abstract：:Septic arthritis still continues to be a common and serious problem at major urban medical centers and is one of the most rapidly destructive forms of acute arthritis. The yearly incidence of bacterial arthritis varies from 2 to 10 per 100,000 in the general population to 30 to 70 per 100,000 in patients with rheumato...

journal_title：Infectious disease clinics of North America

authors： García-De La Torre I

更新日期：2006-12-01 00:00:00

abstract：:An ever-increasing population of immunocompromised individuals, including not only the burgeoning AIDS population but also those patients whose host defenses have been damaged by a wide variety of diseases and their therapies, requires prophylaxis against infectious diseases. Existing vaccines can provide some benefit...

journal_title：Infectious disease clinics of North America

authors： Hibberd PL,Rubin RH

更新日期：1990-03-01 00:00:00

abstract：:The viral hemorrhagic fever (VHF) syndrome is a potentially life-threatening infection typified by a combination of a capillary leak syndrome and bleeding diathesis. Most but not all agents causing VHF are arboviruses, with transmission to humans resulting from an arthropod bite. Agents of VHF affect humans on all con...

journal_title：Infectious disease clinics of North America

authors： Meltzer E

更新日期：2012-06-01 00:00:00

abstract：:Animal models have proven to be invaluable in bridging the gap between in vitro susceptibility testing of an antibiotic and anticipating results obtained in clinical studies. Variables such as antibiotic concentration, inoculum of organism, and pharmacokinetic parameters of the drug can be carefully controlled to prov...

journal_title：Infectious disease clinics of North America

authors： Tunkel AR,Scheld WM

更新日期：1989-09-01 00:00:00

abstract：:Oral mucositis is a serious complication of cancer therapy and in severely immunosuppressed patients. In immunosuppressed patients, the signs and symptoms of infection often are muted because of limited host response, and accurate diagnosis and appropriate treatment may be difficult. Prevention of mucosal breakdown, s...

journal_title：Infectious disease clinics of North America

authors： Epstein JB

更新日期：2007-06-01 00:00:00

abstract：:Although a small number of infections in total joint replacements are blood borne from distant sources, most infections appear to have been derived at operation. Strenuous attempts to reduce this risk by cleaning the air in the wound environment, coupled with prophylactic antibiotics, have reduced infection rates by a...

journal_title：Infectious disease clinics of North America

authors： Gillespie WJ

更新日期：1990-09-01 00:00:00

abstract：:A polyvalent vaccine has been prepared from the capsular polysaccharide of 24 different serotypes of Klebsiella spp. Nearly 200 volunteers have received this vaccine. It is very well tolerated and elicits both binding (ELISA) and functional antibody to 21 of 24 antigens. Antibodies were also detected against 10 seroty...

journal_title：Infectious disease clinics of North America

authors： Cross AS,Sadoff JC,Furer E,Cryz SJ Jr

更新日期：1990-06-01 00:00:00

abstract：:Heart transplant remain the definitive therapy for end-stage heart failure but is limited by the availability of suitable donors. Ventricular assist devices (VAD) are designed as mechanical pumps to supplement or replace the function of damaged ventricles and maintain appropriate blood flow in patients with end-stage ...

journal_title：Infectious disease clinics of North America

authors： Teoh TK,Hannan MM

更新日期：2018-12-01 00:00:00

abstract：:This article familiarizes the clinician with the principles of bacterial susceptibility testing and reporting to facilitate communication with the clinical microbiology laboratory. The emergence of resistance in nearly all commonly isolated bacterial organisms has highlighted the need for ongoing dialogue between the ...

journal_title：Infectious disease clinics of North America

authors： Joyce M,Woods CW

更新日期：2004-09-01 00:00:00

abstract：:The ability of a host to sense invasion by a pathogenic organism, and to respond appropriately to control infection, is paramount to survival. To that end, an array of receptors and binding proteins has evolved as part of the innate immune system to detect Gram-negative bacteria. This article reviews the role of CD14,...

journal_title：Infectious disease clinics of North America

authors： Ingalls RR,Heine H,Lien E,Yoshimura A,Golenbock D

更新日期：1999-06-01 00:00:00

abstract：:Pneumonia remains a major cause of morbidity and mortality in the immunocompromised host. The type and timing of immunosuppression will predispose the patient to infections with certain pathogens. This article discusses the types of immunosuppression and their infectious and noninfectious implications. Key points of t...

journal_title：Infectious disease clinics of North America

authors： Collin BA,Ramphal R

更新日期：1998-09-01 00:00:00

abstract：:In older adults, pathophysiologic, clinical, and environmental factors all affect the presentation of infections. We explore how age-related changes influence the manifestation and evaluation of infections in this population. Specific topics include immunosenescence, age-related organ-specific physiologic changes, and...

journal_title：Infectious disease clinics of North America

authors： El Chakhtoura NG,Bonomo RA,Jump RLP

更新日期：2017-12-01 00:00:00

abstract：:Tyrosine kinase inhibitors represent the standard of care for several diseases and drug targets in hematologic malignancies. Infectious complications vary by disease status and prior therapy, but overall incidence of infections generally is low. In chronic diseases, such as chronic myeloid leukemia and chronic lymphoc...

journal_title：Infectious disease clinics of North America

authors： Kin A,Schiffer CA

更新日期：2020-06-01 00:00:00

abstract：:Infectious complications remain a major source of morbidity and mortality for patients with end-stage renal disease on dialysis. The majority of these complications are related to dialysis access devices, and as such represent a potentially modifiable risk factor. This article reviews the important infectious complica...

journal_title：Infectious disease clinics of North America

authors： Bagdasarian N,Heung M,Malani PN

更新日期：2012-03-01 00:00:00

abstract：:Preventing traveler's diarrhea is usually a matter of common sense, good luck, and the host's ability to defend against enteric pathogens, particularly enterotoxigenic Escherichia coli. Untreated tap water, ice cubes, unpasteurized milk products, salads, food from street vendors, and dining in unhygienic-appearing res...

journal_title：Infectious disease clinics of North America

authors： Tellier R,Keystone JS

更新日期：1992-06-01 00:00:00

abstract：:The diagnostic approach to the compromised host with CNS infection depends on an analysis of the patient's clinical manifestations of CNS disease, the acuteness or subacuteness of the clinical presentation, and an analysis of the type of immune defect compromising the patient's host defenses. Most patients with CNS in...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2001-06-01 00:00:00

abstract：:Influenza is a zoonotic respiratory virus that affects birds, mammals, and humans. Influenza viruses are unique in their genetic instability, which frequently results in antigenic drift or shift. Antigenic shifts are responsible for influenza epidemics. Influenza A pandemics have been responsible for millions of death...

journal_title：Infectious disease clinics of North America

authors： Cunha BA

更新日期：2004-03-01 00:00:00

abstract：:Oral lesions are easily visualized and often are signs of systemic diseases. Clinical diagnosis of viral and fungal infections can sometimes be confusing because many lesions will have similar clinical presentations. This article reviews the more common viral- and fungal-associated lesions found in the oral cavity in ...

journal_title：Infectious disease clinics of North America

authors： Glick M,Siegel MA

更新日期：1999-12-01 00:00:00