Abstract:
:Community-acquired pneumonia (CAP) is the leading cause of death from infectious diseases in the United States. The mortality rate due to severe CAP has shown little improvement over the past few years, with a rate as high as 50% mainly in patients admitted to intensive care units. Death and adverse outcomes from CAP result from a complex interplay between the pathogen and the host. Several therapies have been tested in patients with severe CAP in recent years. This article reviews recent data regarding different treatments including antimicrobials and adjunctive therapies in patients with severe CAP.
journal_name
Infect Dis Clin North Amjournal_title
Infectious disease clinics of North Americaauthors
Sibila O,Restrepo MI,Anzueto Adoi
10.1016/j.idc.2012.11.014subject
Has Abstractpub_date
2013-03-01 00:00:00pages
133-47issue
1eissn
0891-5520issn
1557-9824pii
S0891-5520(12)00130-4journal_volume
27pub_type
杂志文章,评审abstract::Lyme disease affects the nervous system in about 10% to 15% of infected individuals, most commonly causing lymphocytic meningitis. Cranial neuropathies, particularly facial nerve palsy, also occur frequently. Figuring prominently in the European literature, but less emphasized in the United States, is painful radiculi...
journal_title:Infectious disease clinics of North America
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abstract::The viral hemorrhagic fever (VHF) syndrome is a potentially life-threatening infection typified by a combination of a capillary leak syndrome and bleeding diathesis. Most but not all agents causing VHF are arboviruses, with transmission to humans resulting from an arthropod bite. Agents of VHF affect humans on all con...
journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-12-01 00:00:00
abstract::This article focuses on the use of immunoglobulin variable regions, including Id, anti-Id, anticlonotypes, and Id engineering as putative vaccines and vaccine strategies for infectious diseases; and specific discussion of Id systems involving antigenic determinants associated with potentially pathogenic organisms. ...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70041-6
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abstract::Anti-varicella-zoster virus serum antibody assays and their use in vaccine development are described. Of particular interest are FAMA and neutralization assays and the gpELISA. These and other assays are compared and summarized in terms of characteristics including biologic relevance, sensitivity, specificity, and sui...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/s0891-5520(05)70311-1
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abstract::Cytomegaloviruses (CMVs) are DNA viruses and are members of the Herpesviridae family. Morphologically, CMV resembles other herpes viruses, particularly herpes simplex viruses, with important cytopathic differences. CMVs are recognized pathogens that cause community-acquired pneumonia (CAP) in compromised hosts, such a...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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更新日期:2001-09-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
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更新日期:2005-12-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:10.1016/j.idc.2007.03.003
更新日期:2007-06-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-03-01 00:00:00
abstract::Herpes zoster (HZ) is the result of reactivation of latent varicella zoster virus (VZV) and occurs most frequently in older adults. Classically, HZ presents as a unilateral, selflimited, dermatomal rash. Postherpetic neuralgia (PHN) is a common sequela, presenting as severe pain that persists after the rash has resolv...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
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更新日期:2017-12-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1990-12-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1991-12-01 00:00:00
abstract::Inoculation of Treponema pallidum during intimate physical contact is followed by development of a papule that rapidly erodes, yielding the syphilitic chancre. Hematogenous dissemination results in secondary syphilis, a multisystem disease characterized by skin rash, lymph node enlargement, hepatitis, arthritis, and c...
journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1987-03-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
doi:
更新日期:1988-06-01 00:00:00
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journal_title:Infectious disease clinics of North America
pub_type: 杂志文章,评审
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更新日期:1987-03-01 00:00:00
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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更新日期:1991-06-01 00:00:00
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journal_title:Infectious disease clinics of North America
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doi:10.1016/s0891-5520(05)70110-0
更新日期:1999-12-01 00:00:00
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journal_title:Infectious disease clinics of North America
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更新日期:2019-03-01 00:00:00
abstract::Living safely after organ transplantation starts before transplant and continues after transplant. To minimize a solid organ transplant (SOT) recipient's risk for infection and risk for injury, it is important to plan for numerous potential exposures after transplant. These include potential exposure to others with vi...
journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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journal_title:Infectious disease clinics of North America
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更新日期:1995-09-01 00:00:00
abstract::Although only few cases of diphtheria are reported annually in the United States, substantial numbers of adults have declining levels of protective serum antitoxin. A recent outbreak of diphtheria in Sweden emphasizes the importance of reimmunizing adults in diphtheria toxoid, included as part of routine use of tetanu...
journal_title:Infectious disease clinics of North America
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更新日期:1990-03-01 00:00:00