Abstract:
:Cerebral injury following cardiac surgery continues to be a significant source of morbidity and mortality after cardiac surgery. A spectrum of injuries ranging from subtle neurocognitive dysfunction to fatal strokes are caused by a complex series of multifactorial mechanisms. Protecting the brain from these injuries has focused on intervening on each of the various etiologic factors. Although numerous studies have focused on a pharmacologic solution, more success has been found with nonpharmacologic strategies, including optimal temperature management and reducing emboli generation.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Grocott HP,Yoshitani Kdoi
10.1007/s00540-007-0514-1subject
Has Abstractpub_date
2007-01-01 00:00:00pages
367-77issue
3eissn
0913-8668issn
1438-8359journal_volume
21pub_type
杂志文章,评审abstract:PURPOSE:Postoperative pain is an important health-care issue. Patient-controlled analgesia (PCA) is considered the gold standard for systemic postoperative pain treatment. Methadone PCA is used for patients with chronic pain and those in the palliative care setting. However, its efficacy as a first-line drug for acute ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1785-3
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:The present study aimed to investigate the effects of different dosages of propofol, that induced different depths of anesthesia, on the local activity and connectivity of nuclei within the cortico-reticulo-thalamic loops, as well as the release of amino acids in those nuclei. METHODS:The nonlinear dynamics an...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02667-9
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:We conducted a survey to clarify the actual circumstances in which the lungs could not be ventilated and the trachea could not be intubated (CVCI). METHODS:A questionnaire was mailed to all the university hospitals in Japan, asking about CVCI they had experienced during induction of anesthesia in 1998, and bef...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-003-0187-3
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVES:When physicians become patients, they may expect special privileges, extra attention from caregivers, and non-routine treatments. Consequently, physician patients may not be treated per routine-which possibly worsens care rather than improving it. We thus tested the primary hypothesis that in-hospital mortal...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2273-3
更新日期:2017-02-01 00:00:00
abstract:PURPOSE:Intravenous infusion of lidocaine attenuates the stress response to surgery. We aimed to evaluate the effects of perioperative lidocaine on the hemodynamic and hormonal responses for cesarean delivery. METHODS:After the gaining of ethical approval, 90 patients scheduled for elective cesarean delivery were rand...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-009-0738-3
更新日期:2009-01-01 00:00:00
abstract::May-Hegglin anomaly (MHA) is an inherited autosomal dominant disorder characterized by giant platelets and inclusion bodies in granulocytes, and thrombocytopenia. There is no consensus on the perioperative management of this disorder. We report a case involving a patient with MHA who was perioperatively managed withou...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2522-8
更新日期:2018-08-01 00:00:00
abstract:PURPOSE:Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during pai...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2296-9
更新日期:2017-04-01 00:00:00
abstract::To study the effects of repeated ketamine administration (0: saline, 12.5, 25, and 50 mg·kg-1 every 3 days for a total of five times, subcutaneously) on the central muscarinic acetylcholine receptors (mAchRs), receptor binding assays of mAchR were carried out in the forebrain of mice, using [3H]quinuclidinyl benzilate...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02479877
更新日期:1995-09-01 00:00:00
abstract:PURPOSE:The present case-control study was conducted to evaluate whether acute normovolemic hemodilution (ANH) can reduce the need for perioperative allogeneic blood transfusion (ABT) and affect the incidence of perioperative complications in free-flap reconstruction of the head and neck. METHODS:This single-center, r...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-019-02714-5
更新日期:2020-04-01 00:00:00
abstract:PURPOSE:Painful neuropathic conditions of cancer pain often show little response to nonopioid and opioid analgesics but may be eased by antidepressants and anticonvulsants. Although gabapentin is effective in the treatment of neuropathic pain in patients with cancer, some patients experience intolerable side effects su...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0913-6
更新日期:2010-06-01 00:00:00
abstract:PURPOSE:The study was planned to compare the sensitivity of a twitch neuromuscular monitoring test, the train-of-four (TOF), with a tetanic test, double-burst stimulation (DBS), during a subclinical dose of vecuronium. METHODS:Twenty consenting. ASA I patients (16 to 65 years of age) of both sexes were studied. The ul...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02480738
更新日期:1997-12-01 00:00:00
abstract:PURPOSE:The effects of midazolam-thiopental coinduction on recovery were investigated and compared with thiopental induction. METHODS:Fifty patients, ASA 1 or 2, undergoing minor orthopedic surgery, were randomly divided into coinduction and thiopental groups. During preoxygenation, the patients received midazolam 0.1...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400170044
更新日期:2001-01-01 00:00:00
abstract:PURPOSE:Midazolam premedication administered by the intranasal route is noninvasive with good bioavailability. Atomised intranasal midazolam spray ensures accurate drug dosage and better patient acceptability, with rapid onset of action and virtually complete absorption. METHODS:Sixty pediatric patients scheduled for ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1341-6
更新日期:2012-06-01 00:00:00
abstract::Admission on the day of surgery for elective cardiac and non-cardiac surgery has been established as a prevalent, critical practice. This approach realizes medical, logistical, psychological and fiscal benefits, and its success is predicated on an effective outpatient pre-operative evaluation. The establishment of a h...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2139-8
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Epinephrine added to local anesthetic agents for spinal anesthesia is frequently used to prolong the duration of anesthesia. Epinephrine stimulates the alpha-adrenoceptor, and it is known that the alpha2-adrenoceptor agonists have a central inhibitory effect. We investigated the effect of intrathecal epinephrin...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00540-004-0233-9
更新日期:2004-01-01 00:00:00
abstract::The electroencephalograms (EEG) of 55 children under isoflurane anesthesia were studied to elucidate any change in pattern with age. The children ranged from 1 month to 14 years of age were divided into six age groups. The standard minimum alveolar concentration (MAC) was determined in each group. Anesthesia was induc...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514699
更新日期:1994-06-01 00:00:00
abstract:PURPOSE:To investigate the differences in recovery of postural stability, after obtaining similar intravenous sedation levels with midazolam, in elderly and younger patients undergoing dental surgery. METHODS:We studied 15 elderly patients (>65 years) and 15 younger patients (<55 years) after intravenous sedation. Mid...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400200024
更新日期:2002-01-01 00:00:00
abstract:PURPOSES:In the present study, we investigated whether flurbiprofen axetil (FA) alleviates hypoxemia during one-lung ventilation (OLV) by reducing the pulmonary shunt/total perfusion (Q s/Q t) ratio, and examined the relationship between the Q s/Q t ratio and the thromboxane B2 (TXB2)/6-keto-prostaglandin F1α (6-K-PGF1...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-015-2060-6
更新日期:2015-12-01 00:00:00
abstract::The hemodynamic and metabolic changes in hypotensive state induced with prostaglandin E1 (PGE1) or trimetaphan (TMT) infusion were investigated in dogs. Mean arterial pressure was decreased by about 50% with 1.58 microg/kg/min of PGE1 or 45 microg/kg/min of TMT. Heart rate, pulmonary capillary wedge pressure and centr...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030210
更新日期:1989-09-01 00:00:00
abstract::Cardiac surgery is associated with a high incidence of cardiovascular and other complications during the perioperative period that translate into increased mortality and prolonged hospital stays. Safe comprehensive perioperative management is required to eliminate these adverse events. Dexmedetomidine is a selective α...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-014-1857-z
更新日期:2015-02-01 00:00:00
abstract::The incidence of noncardiac surgery in patients with the Fontan circulation has increased over the years due to the elongated life expectancy of these patients. In patients with the Fontan circulation, pulmonary blood flow is passive, so it is important to keep pulmonary vascular resistance low. One-lung ventilation (...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1333-6
更新日期:2012-06-01 00:00:00
abstract:PURPOSE:The recommended method for elucidating the effects of strong ions other than lactate on acid-base balance is to calculate the non-lactate strong ion difference (SIDnl). A relationship between HCO3 (-) and SIDnl in hyperchloremic patients has already been demonstrated; in the present study, the relationships bet...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1007/s00540-016-2158-5
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:Because blood concentrations of local anesthetics sometimes reach toxic levels after transversus abdominis plane (TAP) block, reduction of the dose has been necessary to reduce the risk of systemic toxicity. We therefore investigated the effects of TAP block with 0.25 % levobupivacaine (100 mg) on postoperative...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-015-1993-0
更新日期:2015-08-01 00:00:00
abstract:PURPOSE:Increased glucose variability may be associated with worse outcomes in critically ill patients. Hyperinsulinemic normoglycemia provides intensive glucose control during surgery and may reduce glucose variability. Our objective was to compare glycemic variability between two methods of glucose control in cardiac...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2295-x
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:Local epinephrine infiltration often causes beta1-adrenoceptor-mediated tachycardia, hypertension, and arrhythmia. Landiolol, a short acting beta1-adrenoceptor blocker, may represent the most ideal agent to attenuate these adverse effects. In this study, we examined the effects of landiolol on the hemodynamic c...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00540-004-0281-1
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:The purpose of this study was to determine whether intraoperative infusion of remifentanil induces acute tolerance to opioids, and compare the postoperative pain and opioid consumption by the effect site concentrations of remifentanil. METHODS:One hundred and ninety-eight patients undergoing gastrectomy were r...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2569-6
更新日期:2018-12-01 00:00:00
abstract::A syringe pump is used to inject precise doses of drugs having a strong action; for example, vasoactive drugs. Unexpected and undetected halt of a syringe pump can lead to potentially life-threatening complications. We experienced a sudden halt in the movement of a syringe pump (Terufusion syringe pump; Terumo, Tokyo,...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-005-0382-5
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:There are no sufficient evidences for the sedative effect of gabapentin during anesthesia, especially intravenous sedation (IVS). The purpose of this study was to evaluate the sedative effect of gabapentin as preanesthetic medication during the IVS with propofol. METHODS:10 volunteer subjects joined this study...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
doi:10.1007/s00540-018-2559-8
更新日期:2018-12-01 00:00:00
abstract::A substantial proportion of patients with coronavirus disease 19 (COVID-19) develop severe respiratory failure. Although the exact pathophysiology of severe COVID-19 pneumonia remains unknown and the characteristics of these patients are heterogeneous, the acute respiratory failure often fulfills criteria for acute re...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02845-0
更新日期:2020-08-31 00:00:00
abstract::We report three cases with systolic anterior motion (SAM) after mitral valve plasty. Preoperative mitral valve morphology is a risk factor for SAM. The morphological characteristics of SAM have been revealed in several studies. We found a small distance between coaptation and the interventricular septum in all cases, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1731-4
更新日期:2014-06-01 00:00:00