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Anesthetic management without perioperative platelet transfusion for cervical laminectomy and laminoplasty in a case of May-Hegglin anomaly.

Abstract：

:May-Hegglin anomaly (MHA) is an inherited autosomal dominant disorder characterized by giant platelets and inclusion bodies in granulocytes, and thrombocytopenia. There is no consensus on the perioperative management of this disorder. We report a case involving a patient with MHA who was perioperatively managed without platelet transfusion for cervical laminectomy and laminoplasty. In our case, the platelet count was measured to be 0.6 × 104/µL using an automatic blood cell counter. Peripheral blood smear and genetic test analyses were performed, leading to a definitive diagnosis of MHA. However, clot retraction, serotonin release, and platelet aggregation were normal. Total intravenous anesthesia with propofol and remifentanil, in combination with intermittent injection of fentanyl, was administered. The total blood loss volume was 300 mL, and perioperative course was uneventful. Visual platelet count and platelet function were preserved in this case, although platelet or red blood cell transfusion was not performed. No bleeding tendency was observed during perioperative management.

journal_name

J Anesth

journal_title

Journal of anesthesia

authors

Kumemura M,Omae T,Kou K,Sakuraba S,Niimi N,Kunishima S

doi

10.1007/s00540-018-2522-8

subject

Has Abstract

pub_date

2018-08-01 00:00:00

pages

641-644

issue

4

eissn

0913-8668

issn

1438-8359

pii

10.1007/s00540-018-2522-8

journal_volume

32

pub_type

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