Abstract:
PURPOSE:To investigate the differences in recovery of postural stability, after obtaining similar intravenous sedation levels with midazolam, in elderly and younger patients undergoing dental surgery. METHODS:We studied 15 elderly patients (>65 years) and 15 younger patients (<55 years) after intravenous sedation. Midazolam was carefully titrated over 4-5 min until slow response to verbal commands, ptosis of the eyelid, or slight slurring of speech was obtained. Parameters were postural balance tests and an addition test, as a psychomotor function test. RESULTS:The dose of midazolam in the elderly group (0.045 +/- 0.012 mg.kg(-1)) was 62% of that in the younger group (0.074 +/- 0.026 mg.kg(-1)). In evaluation of the percentile rank of a balance test with a visual feedback system, which contained a dynamic balance element, recovery at 60 min in the elderly group was significantly slower than that in the younger group. However, the recovery times for the balance test and the addition test, at which the significantly changed values were restored to the baseline values, were 120 min and 90 min, respectively, in both groups. CONCLUSION:In the recovery from sedation, elderly patients had more difficulty in acquiring postural adjustment during movement than in maintaining a standing posture. If the dose is carefully administered, however, even elderly patients might be able to return home 2 h after midazolam administration, as could the younger patients.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Fujisawa T,Suzuki S,Tanaka K,Kamekura N,Fukushima K,Kemmotsu Odoi
10.1007/s005400200024subject
Has Abstractpub_date
2002-01-01 00:00:00pages
198-202issue
3eissn
0913-8668issn
1438-8359journal_volume
16pub_type
杂志文章abstract:PURPOSE:This study aimed to investigate the efficacy of the ClearSight™ system (Edwards Lifesciences, Irvine, CA) for reducing the incidence of hypotension compared with the traditional oscillometric blood pressure monitoring in cesarean delivery under spinal anesthesia. METHODS:Forty patients undergoing cesarean deli...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-018-2560-2
更新日期:2018-12-01 00:00:00
abstract::Fifteen infants and children (M = 7, F = 8), aged from 0 to 13 years, who underwent cardiac catheterization and cardioangiography under ketamine-diazepam anesthesia were the subjects of this study. The effect of a contrast medium, isolamate sodium (66.8%) on the plasma somolality and vasopressin concentration was stud...
journal_title:Journal of anesthesia
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journal_title:Journal of anesthesia
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abstract::Recent publications provided controversial results indicating that perioperative heparin bridging anticoagulation (HBA) increased the bleeding risk without decreasing the thromboembolic risk in patients undergoing minor surgery. To investigate if this is also the case in high-risk patients undergoing major abdominal m...
journal_title:Journal of anesthesia
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更新日期:2016-08-01 00:00:00
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journal_title:Journal of anesthesia
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journal_title:Journal of anesthesia
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更新日期:2021-02-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-005-0351-z
更新日期:2006-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2018-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2017-10-01 00:00:00
abstract::The direct effects of nitrous oxide on left ventricular contractility and myocardial oxygen consumption (MVO2) in the ischemic isolated rat heart were studied. The rat heart was isolated and perfused by a Langendorf technique. The aortic stump was cannulated and the heart was perfused with Kumpeis solution bubbled wit...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514658
更新日期:1994-09-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1766-6
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:Dexmedetomidine acts as a selective α2-adrenergic receptor agonist and an imidazoline receptor agonist, both of which are known to affect insulin secretion. Here, we investigated the effects of clinically relevant concentrations of dexmedetomidine on insulin secretion under in vivo conditions. Furthermore, its ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1943-2
更新日期:2015-06-01 00:00:00
abstract::There has been no study comparing the advantage and disadvantage of various antihypertensive agents during surgery for pheochromocytomas because the study is difficult in clinical setting. In the present experiments using dogs, after increasing the arterial blood pressure with norepinephrine, we decreased it to the ba...
journal_title:Journal of anesthesia
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更新日期:1991-10-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2003-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1292-3
更新日期:2012-04-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1938-z
更新日期:2015-06-01 00:00:00
abstract:PURPOSE:Flexible fiber-optic bronchoscope-guided orotracheal intubation is a valuable technique with demonstrated benefits in the management of difficult airways. Despite its popularity with anesthesia providers, the technique is not fail-safe and airway-related complications secondary to failed intubation attempts rem...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-014-1920-9
更新日期:2015-04-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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pub_type: 杂志文章,实务指引
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更新日期:2014-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-0907-4
更新日期:2010-06-01 00:00:00
abstract::The influence of sevoflurane on lidocaine-induced convulsions was studied in cats. The convulsive threshold (mean +/- SD) was 41.4 +/- 6.5 mg. l(-1) with lidocaine infusion (6 mg.kg(-1).min(-1)), increasing significantly to 66.6 +/- 10.9 mg. l(-1) when the end-tidal concentration of sevoflurane was 0.8%. However, the ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050060
更新日期:1991-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054000040303
更新日期:1990-10-01 00:00:00
abstract::Anesthesiologists daily witness the consequences of tobacco use, the most common preventable cause of death. Smoking-related diseases such as atherosclerosis and chronic obstructive pulmonary disease increase anesthetic risk, and even smokers without overt disease are at increased risk for morbidity such as pulmonary ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
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更新日期:2007-01-01 00:00:00
abstract::We report a case of hypermagnesemia in a hospitalized patient after prolonged laxative use; due to preexisting impaired consciousness and digestive problems, the hypermagnesemia was difficult to detect until it almost became fatal. A 64-year-old man who was a patient at another hospital for treatment of head injury an...
journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2007-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
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更新日期:2013-12-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:1992-07-01 00:00:00
abstract::Cardiac surgery is associated with a high incidence of cardiovascular and other complications during the perioperative period that translate into increased mortality and prolonged hospital stays. Safe comprehensive perioperative management is required to eliminate these adverse events. Dexmedetomidine is a selective α...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
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更新日期:2015-02-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:2011-08-01 00:00:00