Abstract：
PURPOSE:The effects of midazolam-thiopental coinduction on recovery were investigated and compared with thiopental induction. METHODS:Fifty patients, ASA 1 or 2, undergoing minor orthopedic surgery, were randomly divided into coinduction and thiopental groups. During preoxygenation, the patients received midazolam 0.1 mg.kg(-1) (coinduction group) or saline (thiopental group) 1 min before induction of anesthesia with thiopental. Isoflurane and nitrous oxide were used to maintain anesthesia. Isoflurane concentration was adjusted to keep blood pressure within +/-20% of the preoperative value. The time to awaken (open eyes, give name and birth-date) and the time to discharge readiness were recorded. Psychomotor tests, including simple light reaction time (SLRT), sedation analogue scale (SAS), and digit span test, were performed pre- and postoperatively. RESULTS:The induction dose of thiopental was significantly lower in the coinduction group. End-tidal isoflurane concentration during surgery was also lower in the coinduction group. There were no significant differences in awakening times and discharge readiness between the two groups. Although SAS values were lower in the coinduction group than in the thiopental group 8 and 24 h after anesthesia, other test results were similar in both groups. The frequency of nausea and vomiting in the recovery period was lower in the coinduction group. CONCLUSION:We conclude that midazolam-thiopental coinduction is a suitable technique when used in conjunction with isoflurane in day-case surgery.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Baykara N,Sahin T,Toker Kdoi
10.1007/s005400170044subject
Has Abstractpub_date
2001-01-01 00:00:00pages
6-10issue
1eissn
0913-8668issn
1438-8359journal_volume
15pub_type
临床试验,杂志文章,随机对照试验abstract：PURPOSE:Propofol and ketamine have become progressively popular in electroconvulsive therapy (ECT) anesthesia, although propofol shortened seizure duration and ketamine might cause cardiotoxicity, psychotic episodes, and delayed recovery. Ketofol is a combination of ketamine and propofol, and the current study was desi...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-012-1378-6
更新日期：2012-08-01 00:00:00
abstract：:Cerebral injury following cardiac surgery continues to be a significant source of morbidity and mortality after cardiac surgery. A spectrum of injuries ranging from subtle neurocognitive dysfunction to fatal strokes are caused by a complex series of multifactorial mechanisms. Protecting the brain from these injuries h...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-007-0514-1
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:We investigated the mechanism by which inhibition of carbonic anhydrase (CA) increases organ blood flow. METHODS:Regional blood flow (rBF) in white rabbits anesthetized with ketamine/urethane was measured in the kidney, liver, stomach wall, and abdominal muscle by means of laser blood flow probes. Data obtaine...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/BF02480036
更新日期：1997-09-01 00:00:00
abstract：PURPOSES:In the present study, we investigated whether flurbiprofen axetil (FA) alleviates hypoxemia during one-lung ventilation (OLV) by reducing the pulmonary shunt/total perfusion (Q s/Q t) ratio, and examined the relationship between the Q s/Q t ratio and the thromboxane B2 (TXB2)/6-keto-prostaglandin F1α (6-K-PGF1...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-015-2060-6
更新日期：2015-12-01 00:00:00
abstract：PURPOSE:We assessed the accuracy of a point-of-care blood gas analyzer in providing data from saline samples obtained by gastrointestinal tonometry (Tonometrics Catheter; Tonometrics Division, Instrumentarium, Helsinki, Finland) for the calculation of intramucosal pH (pHi) and the P(CO)(2) gap (intramucosal P(CO)(2) - ...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-003-0209-1
更新日期：2004-01-01 00:00:00
abstract：:Within the airway management field, simulation has been used as a tool of training for over 40 years. Simulation training offers a chance of active involvement for the trainees. It can effectively enhance and upgrade the knowledge and skills of the trainees in airway management, and subsequently decrease medical error...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-015-2116-7
更新日期：2016-04-01 00:00:00
abstract：:Brachial plexus block is commonly used for upper limb surgery. Although the procedure is safe, it may be associated with some life-threatening complications. We performed right-sided supraclavicular brachial plexus block for below-elbow amputation in a 45-year-old female. At completion of the block the patient develop...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-010-1076-1
更新日期：2011-04-01 00:00:00
abstract：:The coronavirus disease 2019 (COVID-19) pandemic is caused by a coronavirus that is transmitted primarily via aerosol, droplets or direct contact. This may place anesthetists at higher risk of infection due to their frequent involvement in aerosol-generating airway interventions. Many anesthethetic COVID-19 guidelines...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-020-02819-2
更新日期：2020-12-01 00:00:00
abstract：PURPOSE:Newborns are often sedated during MRI but sedation itself creates adverse events and management is more challenging in this environment. Oral glucose/sucrose administration has been studied in newborns during painful procedures; however, its effectiveness in keeping newborns sleepy and motionlessness during pai...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-016-2296-9
更新日期：2017-04-01 00:00:00
abstract：:Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity. However, the effect of directly delivering levobupivacaine into tracheal smooth muscle has not been adequately explored. We performed this study to determine the in vitro effects of levobupivacaine on iso...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-015-2026-8
更新日期：2015-10-01 00:00:00
abstract：PURPOSE:In emergency situations, rescuers occasionally must secure the airway while the patient is in a position other than the ideal supine position. We hypothesized that the laryngeal mask airway Supreme(®) (Supreme) may be useful for emergent airway management in several positions and compared the utility of the Sup...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-011-1145-0
更新日期：2011-08-01 00:00:00
abstract：:Laparoscopic adjustable gastric banding (LAGB) is a common type of bariatric surgery worldwide, though not so in Japan. Here we report the anesthetic management of LAGB in ten Japanese patients with morbid obesity. General anesthesia was induced with propofol, fentanyl, and vecuronium bromide and maintained with sevof...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-007-0529-7
更新日期：2007-01-01 00:00:00
abstract：PURPOSE:The use of volatile anesthetics is reportedly related to altered cerebrovascular carbon dioxide (CO2) reactivity. We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke. METHODS:Twenty-four patients with previous stroke and 20 pat...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-008-0608-4
更新日期：2008-01-01 00:00:00
abstract：:The acute neuroinflammatory response to surgery may play a key pathogenic role in postoperative delirium (POD). Here, we investigated the contribution of acute postoperative pain to neuroinflammation and related delirium-like behaviors after surgery in adult and aged rats. Animals were assigned into four groups: contr...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-019-02635-3
更新日期：2019-06-01 00:00:00
abstract：PURPOSE:Morphine is a powerful analgesic but its effect is often diminished owing to the development of tolerance. It has been suggested that morphine activates microglia through its action on the toll-like receptor 4 (TLR4) in the spinal cord, leading to suppression of the morphine effect. However, it has not been exa...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-012-1469-4
更新日期：2013-02-01 00:00:00
abstract：:In many anesthesia textbooks written in English, lidocaine, tetracaine, bupivacaine, ropivacaine, and chloroprocaine are listed as useful local anesthetics for spinal anesthesia. In contrast, T-cain is not included in these lists, even though it has been reported to be suitable for spinal anesthesia in Japan. T-cain w...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-015-2066-0
更新日期：2015-10-01 00:00:00
abstract：:Alveolar capillary dysplasia (ACD), which is a rare and lethal congenital pulmonary anomaly found in newborns, begins its onset or causes deterioration of the infant's condition some time after birth. Various congenital anomalies in combination with ACD have been reported, except for subglottic stenosis. Therefore, we...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-010-1080-5
更新日期：2011-04-01 00:00:00
abstract：:Preeclampsia can cause myriad organ dysfunction, including cranial nerve palsies that pose diagnostic and management dilemmas. We present an unusual case of third nerve palsy, (presenting as diplopia, ptosis) with hypertension, hyperreflexia, proteinuria, easy bruising in a parturient at 34 + 6/52 weeks of twins gesta...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-013-1586-8
更新日期：2013-10-01 00:00:00
abstract：PURPOSE:The diaphragm is one of the organs directly affected by abdominal sepsis. Evidence suggests that sepsis induces diaphragmatic fatigability and that activated neutrophils play a crucial role in the development of diaphragmatic fatigability. In the present study, we investigated whether olprinone, a phosphodieste...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-007-0572-4
更新日期：2008-01-01 00:00:00
abstract：OBJECTIVES:When physicians become patients, they may expect special privileges, extra attention from caregivers, and non-routine treatments. Consequently, physician patients may not be treated per routine-which possibly worsens care rather than improving it. We thus tested the primary hypothesis that in-hospital mortal...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-016-2273-3
更新日期：2017-02-01 00:00:00
abstract：INTRODUCTION:We investigated the continuous infusion rates of rocuronium necessary to obtain the surgical muscle relaxation before, during, and after the Pringle maneuver on patients who underwent hepatectomy. METHODS:Fifteen patients were induced by total intravenous anesthesia with propofol. After obtaining the cali...
journal_title：Journal of anesthesia
pub_type： 临床试验,杂志文章
doi：10.1007/s00540-018-2498-4
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:Intravenous cannulation is a painful and stressful procedure. The objective of this study was to compare the analgesic efficacy of the eutectic mixture of local anesthetics (EMLA(®)) with that of the Valsalva maneuver in adult patients during i.v. cannulation. METHODS:One hundred ninety-five patients were rand...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-012-1540-1
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:Direct hemoperfusion (DHP) with polymixin B-immobilized fiber (PMX) has been reported to be effective for patients with septic shock. The aim of this study was to clarify the mechanism of PMX-DHP effect on septic shock. METHODS:The following parameters were measured in septic shock patients who were treated wi...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-005-0366-5
更新日期：2006-01-01 00:00:00
abstract：:Beta-adrenergic blockers (β-blockers) are clearly indicated for the long-term treatment of patients with systolic heart failure and post-acute myocardial infarction. Early small-scale studies reported their potential benefits for perioperative use; subsequent randomized controlled trials, however, failed to reproduce ...
journal_title：Journal of anesthesia
pub_type： 杂志文章,评审
doi：10.1007/s00540-019-02691-9
更新日期：2020-02-01 00:00:00
abstract：:Neuraxial anesthesia is a common practice in obstetrics. Evidence suggests that preprocedural ultrasound versus the conventional landmark location method accurately identifies a given intervertebral space and predicts the needle insertion depth required to reach the spinal canal. However, whether the preprocedural ult...
journal_title：Journal of anesthesia
pub_type： 杂志文章,meta分析
doi：10.1007/s00540-020-02750-6
更新日期：2020-06-01 00:00:00
abstract：:We describe the anesthetic management of a patient with pectus excavatum, receiving the minimally invasive Nuss operation, which corrects chest wall deformity by insertion of a convex steel bar (pectus bar). An 8-year-old female patient was scheduled for the Nuss operation. The manipulation of the bar in the thorax wa...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-004-0269-x
更新日期：2005-01-01 00:00:00
abstract：:We report on the anesthetic management of a 69-year-old female Jehovah's Witness undergoing cardiopulmonary bypass to replace the ascending aorta; the patient refused transfusion of stored autologous or allogeneic blood products for religious reasons. The strategy involved preoperative hematopoiesis with recombinant h...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-009-0764-1
更新日期：2009-01-01 00:00:00
abstract：:A 75-year-old female patient underwent right vitrectomy under total intravenous anesthesia with propofol, ketamine and fentanyl. During the surgery sudden severe bradycardia (heart rate, 33 beats per min), without hypotension, occurred, which was relatively atropine-insensitive. This event was accompanied by a marked ...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-008-0632-4
更新日期：2008-01-01 00:00:00
abstract：:It is recommended that the period of fasting before elective surgery should be shortened to facilitate a rapid recovery by preventing catabolism. We examined the effects of a short period of fasting on metabolism by performing indirect calorimetry (IC) under general anesthesia. A prospective observational study involv...
journal_title：Journal of anesthesia
pub_type： 杂志文章
doi：10.1007/s00540-014-1950-3
更新日期：2015-06-01 00:00:00
abstract：PURPOSE:We aimed to evaluate postoperative analgesia of morphine, or clonidine, or morphine plus clonidine, added to caudal bupivacaine in children undergoing infra-umbilical urological and genital procedures. METHODS:Eighty patients aged 1-10 years were prospectively enrolled. After the induction of general anesthesi...
journal_title：Journal of anesthesia
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00540-011-1297-y
更新日期：2012-04-01 00:00:00
