Abstract:
PURPOSE:Propofol and ketamine have become progressively popular in electroconvulsive therapy (ECT) anesthesia, although propofol shortened seizure duration and ketamine might cause cardiotoxicity, psychotic episodes, and delayed recovery. Ketofol is a combination of ketamine and propofol, and the current study was designed to evaluate the effect of ketamine, propofol, and ketofol on hemodynamic profile, duration of seizure activity, and recovery times in patients undergoing ECT. METHODS:Ninety patients (44 women, mean age 27.8 ± 7.2 years) in one ECT session were enrolled and randomized to the propofol, ketamine, or ketofol group. Hemodynamic profile duration of seizure activity and recovery times were recorded. RESULTS:Motor seizure duration in the propofol group was significantly decreased compared to other groups (p < 0.001), whereas spontaneous breathing time in the ketamine group statistically increased compared to the propofol group (p = 0.001), and also eye-opening time (p < 0.001) and obeying-command time (p < 0.001) was significantly increased in the ketamine group compared to other groups. Heart rate (HR) at induction (ketamine 91.2 ± 13.6 vs. propofol 77 ± 13.4 and ketofol 79.9 ± 15.6; p < 0.013; p < 0.08, respectively) was statistically significantly increased in the ketamine group compared to other groups, and HR at the third minute (ketamine 92 ± 12.9 vs. propofol 79.4 ± 9.3 and ketofol 81.5 ± 14.2; p < 0.012, p < 0.048) was also statistically significantly increased in ketamine group compared to other groups. CONCLUSION:The ketofol 1:1 mixture is associated with longer mean seizure time than propofol, and shorter mean recovery times than ketamine, with better hemodynamic stability, without any important side effects in ECT anesthesia.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Yalcin S,Aydoğan H,Selek S,Kucuk A,Yuce HH,Karababa F,Bilgiç Tdoi
10.1007/s00540-012-1378-6subject
Has Abstractpub_date
2012-08-01 00:00:00pages
562-7issue
4eissn
0913-8668issn
1438-8359journal_volume
26pub_type
杂志文章,随机对照试验abstract:PURPOSE:Dexmedetomidine acts as a selective α2-adrenergic receptor agonist and an imidazoline receptor agonist, both of which are known to affect insulin secretion. Here, we investigated the effects of clinically relevant concentrations of dexmedetomidine on insulin secretion under in vivo conditions. Furthermore, its ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-014-1943-2
更新日期:2015-06-01 00:00:00
abstract::We compared the characteristics of postoperative pharyngeal morbidity in intubation between the AirWay Scope (AWS) and Macintosh laryngoscope in 68 ASA I-II female patients aged 35-77 years in a randomized, double-blinded, controlled fashion. After induction of general anesthesia, the patient's trachea was intubated u...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-011-1195-3
更新日期:2011-10-01 00:00:00
abstract::In a prospective controlled trial to compare conventional interscalene brachial plexus block (ISBPB) using anatomic landmarks and electro-stimulation with a combined technique of ultrasound guidance followed by nerve stimulation, 60 patients were randomized into 2 matched equal groups: Group A using nerve stimulation ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1366-x
更新日期:2012-08-01 00:00:00
abstract::Within the airway management field, simulation has been used as a tool of training for over 40 years. Simulation training offers a chance of active involvement for the trainees. It can effectively enhance and upgrade the knowledge and skills of the trainees in airway management, and subsequently decrease medical error...
journal_title:Journal of anesthesia
pub_type: 杂志文章,评审
doi:10.1007/s00540-015-2116-7
更新日期:2016-04-01 00:00:00
abstract::We measured plasma epinephrine and norepinephrine concentrations in a rabbit model simulating subarachnoid hemorrhage (SAH), following the injection of prostaglandin F(2alpha) (PGF(2alpha)) into the basal cistern. In this model, plasma epinephrine values increased significantly (to 4.2-fold those before injection), su...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060161
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:For direct laryngoscopy, we compared midline and left-molar approaches with respect to ease of intubation, using a Macintosh blade. We investigated the relationship between failure of the left-molar approach and preoperative risk factors for difficult intubation. METHODS:With local ethics committee approval, 2...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0694-3
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:Intravenous cannulation is a painful and stressful procedure. The objective of this study was to compare the analgesic efficacy of the eutectic mixture of local anesthetics (EMLA(®)) with that of the Valsalva maneuver in adult patients during i.v. cannulation. METHODS:One hundred ninety-five patients were rand...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1540-1
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:Inguinal hernia repair is a common procedure, and can be performed under spinal anesthesia. Although adequate analgesia is crucial to postoperative recovery, the optimal protective analgesic regimen remains to be established. PURPOSE:To investigate the effects of preoperative etoricoxib within a protective ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2368-5
更新日期:2017-10-01 00:00:00
abstract::While the demand for bariatric surgery is increasing, hospital capacity remains limited. The ERABS (Enhanced Recovery After Bariatric Surgery) protocol has been implemented in a number of bariatric centers. We retrospectively compared the operating room logistics and postoperative complications between pre-ERABS and E...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2089-6
更新日期:2016-02-01 00:00:00
abstract:PURPOSE:We previously confirmed the effectiveness of dexmedetomidine (DEX) for stabilizing hemodynamics as well as sparing anesthetics during anesthetic induction in patients undergoing cardiac surgery (Kunisawa et al. in J Clin Anesth 21:194-199, 1). In this study, we investigated whether these effects of DEX continue...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-011-1215-3
更新日期:2011-12-01 00:00:00
abstract::Preeclampsia can cause myriad organ dysfunction, including cranial nerve palsies that pose diagnostic and management dilemmas. We present an unusual case of third nerve palsy, (presenting as diplopia, ptosis) with hypertension, hyperreflexia, proteinuria, easy bruising in a parturient at 34 + 6/52 weeks of twins gesta...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1586-8
更新日期:2013-10-01 00:00:00
abstract::Recently, gastric ultrasonography has been used as a noninvasive portable tool for evaluating gastric content and volume in adults and children. Pediatric patients are not always cooperative, especially younger ones, and it may be difficult to keep them in the appropriate scanning position without sedation. Hence, we ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2204-3
更新日期:2016-10-01 00:00:00
abstract::Small children are physiologically subject to arterial oxygen desaturation. However, few reports have referred to the risk factors related to postanesthetic hypoxemia and the duration of hypoxemia. The purpose of this study was to clarify these two aspects. Eighty-five ASA physical status I infants and children were i...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070016
更新日期:1993-01-01 00:00:00
abstract::In recent decades anesthesia safety has not been improved in low-income countries. This prospective audit describes the incidence of hypoxia and related events detected among a cohort of patients undergoing surgery in the maternity unit at Sylvanus Olympio University Teaching Hospital, Togo, West Africa, by using puls...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2048-2
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Transcutaneous electrical acupoint stimulation (TEAS), a non-invasive and non-pharmacological adjunctive intervention for perioperative analgesia, may also reduce the incidence of postoperative pulmonary complications. The effect of TEAS on video-assisted thoracic surgical (VATS) patients is still unknown, h...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-015-2057-1
更新日期:2017-02-01 00:00:00
abstract::The effect of famotidine on neonates was studied in 34 obstetric patients who underwent elective cesarean section. In the famotidine group, 20 mg of famotidine was intramuscularly injected at 60 min before induction of anesthesia, and 0.5 mg of atropine was injected at 30 min before induction. In the control group, on...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050276
更新日期:1991-07-01 00:00:00
abstract::Although anaphylactoid reactions to local anesthetics are well known, a radioallergosorbent test (RAST) to detect specific drug reagin (IgE) anti-body has not been developed. We established RAST for local anesthetics by using carboxylic acid derivatives of lidocaine, procaine and methylparaben. Serum samples were take...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054090030074
更新日期:1989-03-01 00:00:00
abstract::The effect of verapamil on ventricular dysrhythmias was evaluated using two canine models. In one model, ventricular dysrhythmias were induced by 1% halothane-epinephrine (1.5 approximately 30 micro g/kg/min.) in 20 dogs (Group I). In the other model, ventricular dysrhythmias were induced by digoxin (0.1 approximately...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054080020028
更新日期:1988-03-01 00:00:00
abstract::With the aim to optimize surgical safety, the World Health Organization (WHO) introduced the Surgical Safety Checklist (SSCL) in 2008. The SSCL has been piloted in many countries worldwide and shown to improve both safety attitudes within surgical teams and patient outcomes. In the study reported here we investigated ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1737-y
更新日期:2014-06-01 00:00:00
abstract::Rectal luminal regional P(CO2) (Pr(CO2)) was compared with gastric luminal Pr(CO2) measured by automated air tonometry at intervals of 10 min in 20 children aged 6-16 years scheduled for elective surgery under general anesthesia. In 5 patients, measurement of rectal Pr(CO2) failed because of catheter-related problems....
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章
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更新日期:2006-01-01 00:00:00
abstract:PURPOSE:Direct hemoperfusion (DHP) with polymixin B-immobilized fiber (PMX) has been reported to be effective for patients with septic shock. The aim of this study was to clarify the mechanism of PMX-DHP effect on septic shock. METHODS:The following parameters were measured in septic shock patients who were treated wi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-005-0366-5
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:We compared the insertion performance of the pediatric size 1.5-3 i-gel airway device with that of the ProSeal laryngeal mask airway (PLMA) in anesthetized children in a prospective, randomized, controlled manner. METHODS:We included 134 children, aged 3 months to 15 years, scheduled for elective surgery under...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1477-4
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:Peripheral gangrene (PG) is a known complication requiring limb amputation among sepsis survivors; however, its incidence and associated risk factors remain controversial. We aimed to examine the incidence of limb amputation among sepsis survivors, and to investigate factors independently associated with limb a...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-020-02858-9
更新日期:2021-02-01 00:00:00
abstract::Iatrogenic injury is a difficult situation for a surgeon. Being successful in saving a patient at risk is the major concern in this situation. Once an iatrogenic injury to the superior vena cava (SVC) is found, increasing the intrathoracic pressure is theoretically able to overcome the venous pressure and to alleviate...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0857-x
更新日期:2010-04-01 00:00:00
abstract:PURPOSE:Intrathecal morphine provides superior pain control for patients undergoing cesarean delivery when compared to intravenous opioid patient-controlled analgesia. However, no study has assessed the overall cost associated with each modality as a primary outcome. The aim of this study is to determine the overall co...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2263-5
更新日期:2017-02-01 00:00:00
abstract::Tracheomalacia after thyroidectomy is a life-threatening situation. However, it is difficult to predict postoperative tracheal obstruction with certainty. A case of a 74-year-old woman with a long-standing adenomatous goiter (98 g) is reported. She had undergone partial right lobe thyroidectomy 54 years earlier. After...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1181-9
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:The use of continuous epidural anesthesia in patients with chronic renal failure is rare and controversial. In this study, we compared the effects of epidural versus general anesthesia on early postoperative renal function in patients who underwent renal transplantation surgery. METHODS:Sixty-eight adult patie...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s005400200004
更新日期:2002-01-01 00:00:00
abstract::Mechanical influences independent of chemoreceptor function on ventilatory control were studied in halothane-anesthetized, artificially ventilated patients using the technique reported by Altose et al. (Respir Physiol 66: 171-180, 1986). Contribution of mechanical factor was indirectly assessed by comparing the values...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060387
更新日期:1992-10-01 00:00:00
abstract::Amrinone, a phosphodiesterase inhibitor, is a non-glycosidic noncatecholamine with both vasodilator and positive inotropic effects. We were interested in assessing the effect of amrinone on postischemic cardiac performance in the isolated heart-lung preparation. Twenty-four male Wistar-ST rats were used. They were ran...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02483394
更新日期:1996-12-01 00:00:00
abstract::Bronchial thermoplasty (BT) is a recently introduced bronchoscopic treatment for patients with asthma refractory to pharmacotherapy. Intraprocedural sedation management is important for successful performance of BT. However, the results of general anesthesia in patients undergoing BT have not been well described. The ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2485-9
更新日期:2018-06-01 00:00:00