Abstract:
:Mechanical influences independent of chemoreceptor function on ventilatory control were studied in halothane-anesthetized, artificially ventilated patients using the technique reported by Altose et al. (Respir Physiol 66: 171-180, 1986). Contribution of mechanical factor was indirectly assessed by comparing the values of arterial carbon dioxide tension at which the subjects started breathing efforts during CO(2) loading induced by the following two methods. 1) Partial rebreathing of expired gas and 2) Mechanical hypoventilation (successive decrease in inflation volume). These two maneuvers resulted in a similar rate of increase in end-expiratory carbon dioxide tension. However, contrary to the observation made by Altose et al. in awake volunteers, we found comparable values of ventilatory recruitment threshold for Pa(CO)(2). Thus, we speculate that halothane anesthesia and/or loss of consciousness impair transmission of afferent information from the lung and/or chest wall musculature. Such effects may be responsible for the depression of load compensatory mechanism during anesthesia.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Kochi T,Ide T,Isono S,Mizuguchi Tdoi
10.1007/s0054020060387subject
Has Abstractpub_date
1992-10-01 00:00:00pages
387-94issue
4eissn
0913-8668issn
1438-8359journal_volume
6pub_type
杂志文章abstract::The effects of butorphanol injection on baroreflex control of heart rate were investigated using both pressor and depressor tests in eighteen adult patients. Baroreflex sensitivity was attenuated after butorphanol injection in the pressor test using phenylephrine, whereas it was unchanged in the depressor test using n...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054030070411
更新日期:1993-10-01 00:00:00
abstract:PURPOSE:Local epinephrine infiltration often causes beta1-adrenoceptor-mediated tachycardia, hypertension, and arrhythmia. Landiolol, a short acting beta1-adrenoceptor blocker, may represent the most ideal agent to attenuate these adverse effects. In this study, we examined the effects of landiolol on the hemodynamic c...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00540-004-0281-1
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:Multimodal analgesia increases the chance of successful discharge and pain control after surgery, and pregabalin is being promoted as an effective analgesic, based on placebo-controlled studies. We investigated whether adding pregabalin improved pain control and reduced opioid requests when it was added to a mu...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1447-x
更新日期:2012-12-01 00:00:00
abstract:PURPOSE:Remifentanil has been available in Japan for 3 years. The use of this new opioid is considered a useful adjuvant to general anesthesia. Knowing the exact cost-effectiveness of remifentanil should lead to improved anesthetic outcomes with a reasonable cost. METHODS:This single-blinded, prospective, randomized s...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-010-1006-2
更新日期:2010-12-01 00:00:00
abstract::The pharmacokinetics and pharmacodynamics of vecuronium bromide were studied in patients under general anesthesia of enflurane and nitrous oxide in oxygen. Eighteen patients were randomly divided into two groups which received either 0.05 mg.kg(-1) (low dose group) or 0.20 mg.kg(-1) (high dose group) of vecuronium int...
journal_title:Journal of anesthesia
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s0054020060028
更新日期:1992-01-01 00:00:00
abstract::Enzyme inhibition on anaerobic dehalogenation of halothane by various analgesic or hypnotic agents was investigated in vitro using rat liver microsomal fraction. The production rate of chloro-difluoro-ethylene (CDE) and chloro-trifluoro-ethane (CTE), anaerobic metabolites of halothane, was measured when various concen...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050331
更新日期:1991-10-01 00:00:00
abstract::We explored whether there were large differences in operating room (OR) times for two common procedures performed by multiple surgeons at each of several hospitals thousands of miles apart. Mean OR time, "wheels in" to "wheels out," for ten consecutive cases of each of laparoscopic cholecystectomy and lung lobectomy w...
journal_title:Journal of anesthesia
pub_type: 杂志文章,多中心研究
doi:10.1007/s00540-006-0419-4
更新日期:2006-01-01 00:00:00
abstract::A large amount of pharmacological and clinical evidence supports the abuse potential of propofol. Although previous case reports have indicated that recreational use of propofol is primarily by medical professionals, its spread among the general public has recently been highlighted. This is the first case report to sh...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1275-4
更新日期:2012-04-01 00:00:00
abstract::We measured plasma epinephrine and norepinephrine concentrations in a rabbit model simulating subarachnoid hemorrhage (SAH), following the injection of prostaglandin F(2alpha) (PGF(2alpha)) into the basal cistern. In this model, plasma epinephrine values increased significantly (to 4.2-fold those before injection), su...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060161
更新日期:1992-04-01 00:00:00
abstract::Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity. However, the effect of directly delivering levobupivacaine into tracheal smooth muscle has not been adequately explored. We performed this study to determine the in vitro effects of levobupivacaine on iso...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2026-8
更新日期:2015-10-01 00:00:00
abstract::There has been no study comparing the advantage and disadvantage of various antihypertensive agents during surgery for pheochromocytomas because the study is difficult in clinical setting. In the present experiments using dogs, after increasing the arterial blood pressure with norepinephrine, we decreased it to the ba...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050396
更新日期:1991-10-01 00:00:00
abstract::We report on five patients who underwent MRI-guided focused ultrasound ablation of prostatic cancer under epidural anesthesia with intravenous dexmedetomidine sedation. This pioneering procedure requires an immobile therapeutic field with adequate sedation and analgesia provided to the patients. Duration of the proced...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1189-1
更新日期:2011-10-01 00:00:00
abstract:PURPOSE:Postoperative sore throat (POST) after general anesthesia with endotracheal intubation is a common and undesirable complication. In this study, we evaluated the combined effects of paracetamol and dexamethasone on the prevention of POST in patients after general anesthesia. METHODS:A total of 226 patients sche...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-017-2411-6
更新日期:2017-12-01 00:00:00
abstract::We have performed a systematic literature review and a meta-analysis investigating the effect of beta-adrenergic antagonist on perioperative pain in randomized clinical trials (RCTs). The search included the CENTRAL, CINAHL, EMBASE, and MEDLINE databases (from inception to 10 February 2015). From the retrieved full te...
journal_title:Journal of anesthesia
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00540-015-2041-9
更新日期:2015-12-01 00:00:00
abstract:PURPOSE:We investigated the effect of low-dose droperidol on heart rate-corrected QT (QTc) interval and interaction with propofol. METHODS:Seventy-two patients undergoing upper limb surgery were included in this study. Patients were randomly allocated to one of three groups: group S (n = 24), which received 1 ml salin...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1625-5
更新日期:2013-12-01 00:00:00
abstract::We report here a 59-year-old man with a saber-sheath tracheal narrowing who was scheduled to undergo pharyngeal tumor resection under general anesthesia. The tracheal narrowing was not clearly detected by chest radiography during the preoperative examination, but it was visible on axial computed tomography (CT) images...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0841-5
更新日期:2010-02-01 00:00:00
abstract:BACKGROUND:Cardiac surgery and sternotomy are procedures accompanied by substantial postoperative pain which is challenging to treat. In general, intravenous (IV) opioids are used in the immediate postoperative phase, followed by oral opioids. Oral opioids are easier to use and generally less expensive. Our goal was th...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1770-x
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:It has been suggested that the different degrees of fade induced by nondepolarizing neuromuscular blocking agents in repetitive muscular contractions may be due to the varying affinities or binding kinetics of presynaptic nicotinic receptors. We compared the degree of fade induced by mivacurium, cisatracurium, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400300024
更新日期:2003-01-01 00:00:00
abstract::Holmium laser enucleation of prostate (HoLEP) is being performed with increasing frequency as a minimally invasive alternative to transurethral resection of the prostate (TURP) for the surgical management of benign prostatic hyperplasia (BPH). HoLEP offers the advantage of use of normal saline for irrigation, instead ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-016-2256-4
更新日期:2016-12-01 00:00:00
abstract:PURPOSE:Increased glucose variability may be associated with worse outcomes in critically ill patients. Hyperinsulinemic normoglycemia provides intensive glucose control during surgery and may reduce glucose variability. Our objective was to compare glycemic variability between two methods of glucose control in cardiac...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-016-2295-x
更新日期:2017-04-01 00:00:00
abstract:PURPOSE:We aimed to introduce a simple, lightweight continuous positive airway pressure (CPAP)-delivery device for the nondependent lung during one-lung ventilation, to investigate how the type of three-way stopcocks, and the compliance and resistance of a test lung affect the relationship between the oxygen flow rate ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0681-8
更新日期:2009-01-01 00:00:00
abstract::The influence of sevoflurane on lidocaine-induced convulsions was studied in cats. The convulsive threshold (mean +/- SD) was 41.4 +/- 6.5 mg. l(-1) with lidocaine infusion (6 mg.kg(-1).min(-1)), increasing significantly to 66.6 +/- 10.9 mg. l(-1) when the end-tidal concentration of sevoflurane was 0.8%. However, the ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050060
更新日期:1991-01-01 00:00:00
abstract::Familial dysautonomia is an inherited disorder characterized by autonomic and sensory nervous system neuropathy resulting in extremely labile blood pressure (severe hypertension followed by hypotension). As more patients with familial dysautonomia reach adulthood due to improved medical treatment, perioperative encoun...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0795-7
更新日期:2009-01-01 00:00:00
abstract::While the demand for bariatric surgery is increasing, hospital capacity remains limited. The ERABS (Enhanced Recovery After Bariatric Surgery) protocol has been implemented in a number of bariatric centers. We retrospectively compared the operating room logistics and postoperative complications between pre-ERABS and E...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2089-6
更新日期:2016-02-01 00:00:00
abstract::A 75-year-old female patient underwent right vitrectomy under total intravenous anesthesia with propofol, ketamine and fentanyl. During the surgery sudden severe bradycardia (heart rate, 33 beats per min), without hypotension, occurred, which was relatively atropine-insensitive. This event was accompanied by a marked ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0632-4
更新日期:2008-01-01 00:00:00
abstract::Thirty six patients were received epidural anesthesia with or without buprenorphine (BPN) during upper abdominal surgery. They were divided into three groups of 12 patients as follows; G-I received 20 ml of 1% lidocaine epidurally, G-II received 20 ml of 1% lidocaine epidurally and 0.6 mg BPN intravenously, G-III rece...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054000040242
更新日期:1990-07-01 00:00:00
abstract:PURPOSE:The aim of this pilot study was to evaluate the diagnostic value of pleth variability index (PVI) to predict fluid responsiveness in newborn infants during surgery. METHODS:PVI was continuously recorded in 29 mechanically ventilated newborn infants during surgery, and episodes of clinically indicated volume ex...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1511-6
更新日期:2013-04-01 00:00:00
abstract::We report three cases with systolic anterior motion (SAM) after mitral valve plasty. Preoperative mitral valve morphology is a risk factor for SAM. The morphological characteristics of SAM have been revealed in several studies. We found a small distance between coaptation and the interventricular septum in all cases, ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1731-4
更新日期:2014-06-01 00:00:00
abstract:PURPOSE:Vascular risk factors, including metabolic syndrome, are known to contribute to the development of cognitive dysfunction. We tested the hypothesis that patients with metabolic syndrome are more likely to develop cognitive dysfunction after noncardiac surgery. METHODS:Age- and education-balanced patients (n = 6...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-011-1137-0
更新日期:2011-06-01 00:00:00
abstract::The electroencephalograms (EEG) of 55 children under isoflurane anesthesia were studied to elucidate any change in pattern with age. The children ranged from 1 month to 14 years of age were divided into six age groups. The standard minimum alveolar concentration (MAC) was determined in each group. Anesthesia was induc...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514699
更新日期:1994-06-01 00:00:00