Abstract:
PURPOSE:Postoperative sore throat (POST) after general anesthesia with endotracheal intubation is a common and undesirable complication. In this study, we evaluated the combined effects of paracetamol and dexamethasone on the prevention of POST in patients after general anesthesia. METHODS:A total of 226 patients scheduled for urologic surgery under general anesthesia were randomly assigned to one of two groups. In the DexaPara group (n = 113), dexamethasone (10 mg) and paracetamol (1000 mg) was infused. In the Dexa group (n = 113), dexamethasone (10 mg) alone was given. POST, hoarseness, and dysphagia were monitored. The postoperative wound pain score and perioperative opioid requirements were compared. In addition, complications related to opioids were compared between the groups. RESULTS:The overall incidence of POST was lower in the DexaPara group than in the Dexa group [42 (37%) vs. 72 (64%), p < 0.001]. The incidence of POST while resting at postoperative 1 and 6 h was lower in the DexaPara group than in the Dexa group (p = 0.008 and p = 0.004, respectively). The incidence of postoperative nausea, vomiting, drowsiness, shivering, and headache was comparable between the groups. CONCLUSIONS:Paracetamol and dexamethasone infusion reduced the incidence of POST without serious complications in patients for urologic surgery under general anesthesia.
journal_name
J Anesthjournal_title
Journal of anesthesiaauthors
Lee J,Park HP,Jeong MH,Kim HCdoi
10.1007/s00540-017-2411-6subject
Has Abstractpub_date
2017-12-01 00:00:00pages
869-877issue
6eissn
0913-8668issn
1438-8359pii
10.1007/s00540-017-2411-6journal_volume
31pub_type
杂志文章,随机对照试验abstract:PURPOSE:Midazolam premedication administered by the intranasal route is noninvasive with good bioavailability. Atomised intranasal midazolam spray ensures accurate drug dosage and better patient acceptability, with rapid onset of action and virtually complete absorption. METHODS:Sixty pediatric patients scheduled for ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-012-1341-6
更新日期:2012-06-01 00:00:00
abstract::Iatrogenic injury is a difficult situation for a surgeon. Being successful in saving a patient at risk is the major concern in this situation. Once an iatrogenic injury to the superior vena cava (SVC) is found, increasing the intrathoracic pressure is theoretically able to overcome the venous pressure and to alleviate...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0857-x
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abstract:BACKGROUND:During perioperative care, the continuous measurement of blood pressure (BP) provides superior physiological monitoring compared to intermittent techniques, especially for patients with comorbid conditions such as severe obesity. The current study prospectively assesses the accuracy of a continuous, noninvas...
journal_title:Journal of anesthesia
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doi:10.1007/s00540-014-1835-5
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abstract:AIM:Assessment of breathing on clinical examination requires visualization of "chest" wall movement. However, in mechanically ventilated paralyzed patients, chest expansion is smaller than that of the abdomen. The aim of this study was to determine chest and upper abdominal movements in mechanically ventilated patients...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-013-1703-8
更新日期:2014-04-01 00:00:00
abstract::The direct effects of nitrous oxide on left ventricular contractility and myocardial oxygen consumption (MVO2) in the ischemic isolated rat heart were studied. The rat heart was isolated and perfused by a Langendorf technique. The aortic stump was cannulated and the heart was perfused with Kumpeis solution bubbled wit...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02514658
更新日期:1994-09-01 00:00:00
abstract::Since perioperative anaphylaxis occurs suddenly, and it can be life-threatening, anesthesiologists need to have sufficient knowledge of the epidemiology of perioperative anaphylaxis and appropriate coping strategies to deal with it. Recent studies conducted in Western countries reported the characteristics of perioper...
journal_title:Journal of anesthesia
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更新日期:2021-02-01 00:00:00
abstract:PURPOSE:Peripheral gangrene (PG) is a known complication requiring limb amputation among sepsis survivors; however, its incidence and associated risk factors remain controversial. We aimed to examine the incidence of limb amputation among sepsis survivors, and to investigate factors independently associated with limb a...
journal_title:Journal of anesthesia
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doi:10.1007/s00540-020-02858-9
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abstract::Levobupivacaine has been developed as a safer alternative to bupivacaine because of its reduced systemic toxicity. However, the effect of directly delivering levobupivacaine into tracheal smooth muscle has not been adequately explored. We performed this study to determine the in vitro effects of levobupivacaine on iso...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-015-2026-8
更新日期:2015-10-01 00:00:00
abstract::Treacher Collins syndrome (TCS) is a congenital malformation of craniofacial development; in these patients conventional direct laryngoscopy is very difficult and often unsuccessful because of the upper airway malformation. A 20-year-old man with TCS was scheduled for elective tympanoplasty. The patient showed the cha...
journal_title:Journal of anesthesia
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更新日期:2008-01-01 00:00:00
abstract::There has been no study comparing the advantage and disadvantage of various antihypertensive agents during surgery for pheochromocytomas because the study is difficult in clinical setting. In the present experiments using dogs, after increasing the arterial blood pressure with norepinephrine, we decreased it to the ba...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054010050396
更新日期:1991-10-01 00:00:00
abstract::We measured plasma epinephrine and norepinephrine concentrations in a rabbit model simulating subarachnoid hemorrhage (SAH), following the injection of prostaglandin F(2alpha) (PGF(2alpha)) into the basal cistern. In this model, plasma epinephrine values increased significantly (to 4.2-fold those before injection), su...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s0054020060161
更新日期:1992-04-01 00:00:00
abstract:PURPOSE:The properties of two new-generation CO(2) absorbents, Amsorb Plus (Armstrong Medical, Coleraine, UK) and Drägersorb Free (Drager, Lubeck, Germany), were compared with those of Amsorb (Armstrong Medical) and Sodasorb II (W.R. Grace, Lexington, MA, USA). METHODS:The concentration of compound A produced by each ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-004-0253-5
更新日期:2004-01-01 00:00:00
abstract::Cardiac surgery with cardiopulmonary bypass (CPB) is frequently associated with a complex array of post-operative clinical abnormalities, including low-output syndrome and pulmonary dysfunction. It has been reported that oxygen free radicals are one of the important factors causing reperfusion injury. To determine whe...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02483345
更新日期:1996-06-01 00:00:00
abstract:PURPOSE:We aimed to introduce a simple, lightweight continuous positive airway pressure (CPAP)-delivery device for the nondependent lung during one-lung ventilation, to investigate how the type of three-way stopcocks, and the compliance and resistance of a test lung affect the relationship between the oxygen flow rate ...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0681-8
更新日期:2009-01-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0694-3
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:Morphine is a powerful analgesic but its effect is often diminished owing to the development of tolerance. It has been suggested that morphine activates microglia through its action on the toll-like receptor 4 (TLR4) in the spinal cord, leading to suppression of the morphine effect. However, it has not been exa...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1469-4
更新日期:2013-02-01 00:00:00
abstract:PURPOSE:We hypothesized anterograde amnesia could be predicted by the bispectral index (BIS) during epidural puncture in patients premedicated with intramuscular midazolam. METHODS:We investigated 64 consecutive patients undergoing gynecological laparotomy under general anesthesia combined with epidural anesthesia. Mi...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-009-0748-1
更新日期:2009-01-01 00:00:00
abstract::Anesthetic management of anterior mediastinal masses (AMM) is challenging. We describe the successful anesthetic management of two patients with AMM in which dexmedetomidine was used at supra-sedative doses. Our first case was a 41-year-old man who presented with a 10 x 9 x 11 cm AMM, a pericardial effusion, compressi...
journal_title:Journal of anesthesia
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doi:10.1007/s00540-010-0946-x
更新日期:2010-08-01 00:00:00
abstract::The effect of verapamil on ventricular dysrhythmias was evaluated using two canine models. In one model, ventricular dysrhythmias were induced by 1% halothane-epinephrine (1.5 approximately 30 micro g/kg/min.) in 20 dogs (Group I). In the other model, ventricular dysrhythmias were induced by digoxin (0.1 approximately...
journal_title:Journal of anesthesia
pub_type: 杂志文章
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更新日期:1988-03-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
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更新日期:2010-06-01 00:00:00
abstract::Dexmedetomidine (DEX) for sedation in diagnostic and interventional cardiac catheterization (DICC) has been reported to require other drugs or rescue drugs because of its insufficient sedative effect when used alone. We administered DEX and adjusted its dose according to the bispectral index (BIS) monitor™ for DICC in...
journal_title:Journal of anesthesia
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更新日期:2012-04-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-018-2485-9
更新日期:2018-06-01 00:00:00
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journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-012-1527-y
更新日期:2013-06-01 00:00:00
abstract::We present a life-threatening case of hemothorax resulting from right brachiocephalic vein perforation during right internal jugular vein catheterization. We considered that the guidewire had punctured the right brachiocephalic vein extraluminally and the catheter inserted over the guidewire had enlarged the size of t...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s00540-008-0696-1
更新日期:2009-01-01 00:00:00
abstract:PURPOSE:To investigate the differences in recovery of postural stability, after obtaining similar intravenous sedation levels with midazolam, in elderly and younger patients undergoing dental surgery. METHODS:We studied 15 elderly patients (>65 years) and 15 younger patients (<55 years) after intravenous sedation. Mid...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/s005400200024
更新日期:2002-01-01 00:00:00
abstract::We tested hypertonic saline solution (HS) to determine its effectiveness in surgical procedures for prostatic hypertrophy. We randomly selected 40 patients undergoing elective transurethral resection of the prostate for either infusion of HS (3% NaCl) at 4ml·kg(-1)·min(-1) (HS group) or lactated Ringer's solution (LR)...
journal_title:Journal of anesthesia
pub_type: 杂志文章
doi:10.1007/BF02471385
更新日期:1996-09-01 00:00:00
abstract:PURPOSE:Ultrasound (US)-guided continuous interscalene brachial plexus block (CBPB) is known to provide effective pain relief for arthroscopic rotator cuff repair. This study was conducted to compare analgesic efficacy and forearm muscle tone of the basal infusion rate and bolus dose of 0.2 % ropivacaine for US-guided ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1681-x
更新日期:2014-02-01 00:00:00
abstract:PURPOSE:Postoperative pain is an important health-care issue. Patient-controlled analgesia (PCA) is considered the gold standard for systemic postoperative pain treatment. Methadone PCA is used for patients with chronic pain and those in the palliative care setting. However, its efficacy as a first-line drug for acute ...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1785-3
更新日期:2014-08-01 00:00:00
abstract:PURPOSE:The use of volatile anesthetics is reportedly related to altered cerebrovascular carbon dioxide (CO2) reactivity. We examined the comparative effects of sevoflurane versus isoflurane on cerebrovascular CO2 reactivity in patients with previous stroke. METHODS:Twenty-four patients with previous stroke and 20 pat...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-008-0608-4
更新日期:2008-01-01 00:00:00
abstract:PURPOSE:Nowadays the size of the streamlined liner of the pharynx airway (SLIPA™) is selected by matching the width of the thyroid cartilage of the patient to the widest dimension of the SLIPA™. The objective of this work was to improve the method of selection by matching the distance between the otobasion inferius and...
journal_title:Journal of anesthesia
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00540-013-1571-2
更新日期:2013-08-01 00:00:00