Genetic regulation of arrested development in nematodes: are age-1 and daf-gene orthologs present in Dictyocaulus viviparus?

Abstract:

:In opposite to the free-living soil nematode Caenorhabditis elegans, the genetic regulation of hypobiosis or inhibited or arrested development in parasitic nematodes is completely unknown. In C. elegans, the daf-genes or the age-1 gene are of major importance in signaling pathways regulating arrested development. To investigate if orthologs of these genes are present in the bovine lungworm Dictyocaulus viviparus, a PCR analysis with gene-specific primer combinations was performed. No orthologs of the age-1 or daf-genes could be identified in D. viviparus. The possible differences in the role of the daf-genes concerning arrested development in parasitic and free-living nematodes will be discussed.

journal_name

Parasitol Res

journal_title

Parasitology research

authors

Strube C,von Samson-Himmelstjerna G,Schnieder T

doi

10.1007/s00436-007-0594-8

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

1111-5

issue

4

eissn

0932-0113

issn

1432-1955

journal_volume

101

pub_type

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