Abstract：
:The involvement of protein kinase C in the initiation of free oxygen radical generation by rat leukocytes in response to the nematode Nippostrongylus brasiliensis was investigated. Inhibitors of protein kinase C, trifluoperazine and 1-(5-isoquinolinylsulfonyl)-2-methylpiperazine (H-7), inhibited free radical generation in response to N. brasiliensis in vitro. Neither inhibitor affected free radical generation by the cell-free xanthine/xanthine oxidase system, indicating that the agents did not scavenge free radicals; they also failed to affect leukocyte viability. Furthermore, activators of protein kinase C, the calcium ionophore A23187 and the diacylglycerol 1-oleoyl-2-acetyl-rac-glycerol (OAG), enhanced free radical generation by leukocytes in response to N. brasiliensis in vitro. Thus, protein kinase C apparently plays an important role in the initiation of free radical generation in response to N. brasiliensis; since free radicals may play a critical role in worm expulsion, this implies that protein kinase C may also be important in the rejection of N. brasiliensis from the small intestine of the rat.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Smith NCdoi
10.1007/BF00928421subject
Has Abstractpub_date
1991-01-01 00:00:00pages
521-5issue
6eissn
0932-0113issn
1432-1955journal_volume
77pub_type
杂志文章abstract：:The purpose of the present study was to assess the effect of leaf hexane and chloroform extracts of Aegle marmelos, Andrographis lineata, Andrographis paniculata, Cocculus hirsutus, Eclipta prostrata, and Tagetes erecta on repellent, ovicidal, and oviposition-deterrent activities against Culex tritaeniorhynchus Giles ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1690-8
更新日期：2010-01-01 00:00:00
abstract：:The eggshells of young developmental stages in the uterus are rather thin and homogenous. In the brezel stage of Brugia malayi they are 35 nm thick and 20 nm in Litomosoides carinii. In young developmental stages up to brezel stages the eggshells bind the lectins WGA, DBA and PNA labelled with colloidal gold. This sho...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00535333
更新日期：1987-01-01 00:00:00
abstract：:The giant thorny-headed worm Macracanthorhynchus hirudinaceus is a zoonotic acanthocephalan species with a worldwide distribution. Its natural definitive hosts are primarily pigs and wild boars (Sus scrofa), and scarabaeid beetles serve as the intermediate host. To date, there has only been one record of this acanthoc...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5922-7
更新日期：2018-07-01 00:00:00
abstract：:Knowledge of species and genotypes on Cryptosporidium involved in human transmission is fundamental in studying the epidemiology of cryptosporidiosis. This is the first study in molecular epidemiology of cryptosporidiosis that has been made in Chile. Cryptosporidium parvum species and genotypes involved in human and b...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1391-x
更新日期：2005-08-01 00:00:00
abstract：:The use of the term guild community as an intermediate level between component and supra-community proves to be advantageous within the different steps of parasite communities. It can comprise more information than a component community but researchers are able to analyse important parts of the supra-community without...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s004360100386
更新日期：2001-06-01 00:00:00
abstract：:NADH- or NADPH-oxidase activity was cytochemically detected at the ultrastructural level during the process of interaction between Trypanosoma cruzi and activated mouse peritoneal macrophages. The reaction product, indicative of enzyme activity, was found in the portion of the plasma membrane of the macrophages to whi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00578506
更新日期：1987-01-01 00:00:00
abstract：:The experimental study investigated the ability of tortoise tick Hyalomma aegyptium to play a role in forming and maintaining natural foci of Q fever. We tested the competence of H. aegyptium larvae to acquire Coxiella burnetii infection from mammals, serve as a C. burnetii vector between mammalian hosts, and be a lon...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2037-1
更新日期：2010-11-01 00:00:00
abstract：:Schistosoma is the causative agent of schistosomiasis, a common infectious disease distributed worldwide. Our previous phosphoproteomic analysis suggested that glycogen synthase kinase 3 (GSK3), a conserved protein kinase in eukaryotes, is likely involved in protein phosphorylation of Schistosoma japonicum. Here, we a...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06731-2
更新日期：2020-07-01 00:00:00
abstract：:A clinical field trial was performed to evaluate the efficacy of imidacloprid, the active ingredient of Advantage 10% Spot-On, against natural lice infestations on dogs. Imidacloprid was highly effective against both sucking (Linognathus setosus) and biting (Trichodectes canis) lice over the 6-week period of the trial...
journal_title：Parasitology research
pub_type： 临床试验,杂志文章
doi：10.1007/s004360050560
更新日期：1999-04-01 00:00:00
abstract：:Thus far, Entamoeba species have been classified based on morphology such as the number of nuclei in mature cysts and their hosts. Using recently developed molecular tools, ruminant Entamoeba spp. are currently classified into four species/genotypes: E. bovis and Entamoeba ribosomal lineages (RL) 1, 2, and 4. However,...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5689-2
更新日期：2018-01-01 00:00:00
abstract：:Global pollinator decline has recently been discussed in the context of honey and bumble bee infections from various pathogens including viruses, bacteria, microsporidia and mites. The microsporidian pathogens Nosema apis, Nosema ceranae and Nosema bombi may in fact be major candidates contributing to this decline. Di...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2640-9
更新日期：2012-04-01 00:00:00
abstract：:Studies of the immune response in chronic helminth infections suggest that parasites modulate the host's immune response. Taenia solium metacestodes, in particular, produce molecules that down-regulate cell-mediated immunity. We have described a small RNA peptide termed metacestode factor (MF) that depresses the murin...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050367
更新日期：1998-01-01 00:00:00
abstract：:Hysterothylacium zhoushanensis sp. nov. collected from the intestine of the flatfish Pseudorhombus oligodon (Bleeker) (Pleuronectiformes: Paralichthyidae) in the East China Sea is described and illustrated by light and scanning electron microscopy. The new species can be easily distinguished from its congeners by the ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3095-3
更新日期：2012-12-01 00:00:00
abstract：:Schistosomiasis japonica remains one important public health concern that cause great loss of humans' health and social-economic development in the Peoples' Republic of China. At the end of 1990s and the beginning of 2000s, there were still about 0.8 million patients and nearly 85 million people living in the epidemic...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3295-5
更新日期：2013-04-01 00:00:00
abstract：:The internal transcribed spacer (ITS) region was used to study the intraspecies variation of Brugia spp. in cat reservoirs. Blood specimens from seven naturally infected cats were collected from two different geographical brugian-endemic areas in Thailand. The DNAPAR tree of these Brugia spp. was constructed using a m...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1352-x
更新日期：2009-06-01 00:00:00
abstract：:Toxoplasma gondii is a zoonotic protozoan of almost all species of mammals and birds. However, no information is available about seroprevalence of the pathogen in stray dogs in seven cities from Inner Mongolia, Jilin, Liaoning province, China. Using the indirect hemagglutination antibody (IHA) test with a cutoff titer...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4746-y
更新日期：2015-12-01 00:00:00
abstract：:Reports of an unusual intraerythrocytic pathogen in amphibian blood have been made for decades; these pathogens appear as membrane-bound vacuoles within erythrocytes. It is now understood that the pathogen is a Rickettsia bacteria, which are obligate intracellular parasites, and most are transmitted by arthropod vecto...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1869-z
更新日期：2010-07-01 00:00:00
abstract：:Schistosomiasis affects more than 200 million people worldwide; another 600 million are at risk of infection. The schistosomulum stage is believed to be the target of protective immunity in the attenuated cercaria vaccine model. In an attempt to identify genes up-regulated in the schistosomulum stage in relation to ce...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2045-1
更新日期：2011-01-01 00:00:00
abstract：:The present work aimed at studying the possible association of HLA antigens with Entamoeba histolytica/E. dispar asymptomatic infection in a Mexican mestizo population. A case-control design was selected for evaluation of the role of genetic markers in parasite infection. For this purpose the HLA-A, HLA-B, and HLA-DR ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050641
更新日期：1999-10-01 00:00:00
abstract：:The genus Plasmodium (Plasmodiidae) ranks among the most widespread intracellular protozoan parasites affecting a wide range of mammals, birds, and reptiles. Little information is available about lizard malaria parasites in South America, and the pathological features of the resulting parasitoses remain unknown or poo...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06756-7
更新日期：2020-08-01 00:00:00
abstract：:Strongyloides stercoralis can cause severe infection both in humans and dogs. Coproparasitological examination has low sensitivity for the diagnosis of this parasite; hence, different diagnostic techniques have been implemented. However, serology and molecular methods have been assessed almost exclusively in humans. I...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-017-5468-0
更新日期：2017-07-01 00:00:00
abstract：:This experimental study on pigs was designed to simulate natural, long-term exposure to Ascaris suum under modern management conditions. Parasite kinetics were followed in pigs receiving A. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931733
更新日期：1992-01-01 00:00:00
abstract：:Increased gametocytemia in infections with resistant strains of Plasmodium species and their enhanced transmissibility are a matter of concern in planning and evaluating the impact of malaria control strategies. Various studies have determined weekly gametocyte carriage in response to antimalarial drugs in clinical tr...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3789-9
更新日期：2014-04-01 00:00:00
abstract：:This study was designed to provide a comprehensive description of the ultrastructure of the esophagus of Trichinella spiralis muscle larvae. Although the esophagus exhibited basically the same structure throughout its entire length, being composed of a single cell-layered epithelium, the basal lamina, and the cuticle,...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931189
更新日期：1988-01-01 00:00:00
abstract：:Mosquitoes (Diptera: Culicidae) are important vectors for a wide range of pathogenic organisms. As large parts of the human population in developed countries live in cities, the occurrence of vector-borne diseases in urban areas is of particular interest for epidemiologists and public health authorities. In this study...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4237-6
更新日期：2015-02-01 00:00:00
abstract：:In vitro leucocyte proliferative responses to parasite antigens and to mitogens as well as lymphocyte sub-types were compared in guinea pigs with genetically determined differences in their ability to express protective immunity against Trichostronylus colubriformis infection. Proliferative responses to parasite antig...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050048
更新日期：2000-04-01 00:00:00
abstract：:One of the main drawbacks of experimental amebiasis is the lack of an adequate animal model for invasive intestinal lesions. Mongolian gerbils are useful because both intestinal and hepatic amebiasis can be produced experimentally with Entamoeba histolytica trophozoites. In this paper we show results obtained with in ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050228
更新日期：1997-01-01 00:00:00
abstract：:In the present study, we have tested the effect of different polyamine inhibitors of the spermidine metabolizing enzymes deoxyhypusine synthase and homospermidine synthase in different chloroquine resistant Plasmodium falciparum strains, in the mosquito Anopheles stephensi (Diptera: Culicidae) and in a Trypanosoma eva...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1162-0
更新日期：2004-09-01 00:00:00
abstract：:In the present study, 29 bank voles (Clethrionomys glareolus) were studied for their endo- and ectoparasite fauna. The rodents were trapped in Dormagen, a city in North Rhine-Westphalia, Germany. A total of ten different parasite species were identified: four endoparasite (four Nematoda) and six ectoparasite (three In...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0725-2
更新日期：2007-12-01 00:00:00
abstract：:The beta-tubulin coding sequences were investigated for the Chinese liver fluke, Clonorchis sinensis. A cDNA library of adult C. sinensis was screened with cDNA probes synthesized by polymerase chain reaction using degenerate primers, and two beta-tubulin cDNAs, CsTB1 and CsTB3, were subsequently cloned. The CsTB1 and...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-009-1512-z
更新日期：2009-10-01 00:00:00
