Response to repeated inoculations with Ascaris suum eggs in pigs during the fattening period. I. Studies on worm population kinetics.


:This experimental study on pigs was designed to simulate natural, long-term exposure to Ascaris suum under modern management conditions. Parasite kinetics were followed in pigs receiving A. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg (baconers). In pigs inoculated twice weekly with 500 eggs, there was an initial marked rise in the numbers of hepatic milk spots, but as early as around week 6 after the start of inoculations and until week 16, at which time the last pigs were slaughtered, the numbers of spots diminished drastically. In pigs receiving only 25 eggs twice weekly, low and moderately fluctuating numbers of spots were seen throughout the experiment. Larvae recoverable from the livers and lungs were observed mainly during the beginning of the experiment. Before patency, immature intestinal worms were found in moderate numbers that showed a rough positive correlation with the dose levels, but at the time at which adult worms started to appear, immature parasites could practically no longer be found. In all, only 10 of 40 pigs harbored adults, and 4 of these 10 pigs harbored 80% of the total worm population. The results show that acquired dose-dependent host responses to A. suum play an important role in regulating the worm population along the migratory route of the parasite and that the final burden of worms in the small intestine is dose-dependent and highly variable.


Parasitol Res


Parasitology research


Eriksen L,Nansen P,Roepstorff A,Lind P,Nilsson O




Has Abstract


1992-01-01 00:00:00












  • Evaluation of antileishmanial potential of Tinospora sinensis against experimental visceral leishmaniasis.

    abstract::The chemotherapeutic interventions against visceral leishmaniasis (VL) are limited and facing serious concerns of toxicity, high cost, and emerging drug resistance. There is a greater interest in new drug developments from traditionally used medicinal plants which offers unprecedented diversity in structures and bioac...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Singh N,Kumar A,Gupta P,Chand K,Samant M,Maurya R,Dube A

    更新日期:2008-02-01 00:00:00

  • Neuroanatomy of Cysticercus cellulosae (Cestoda) as revealed by acetylcholinesterase and nonspecific esterase histochemistry.

    abstract::The nervous system of Cysticercus cellulosae, the metacestode stage of the tapeworm Taenia solium, was delineated using histochemical methods for the localization of the enzyme markers; nonspecific esterase and acetylcholinesterase. The main features of the nervous system include a pair of cerebral ganglia, a circumce...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Vasantha S,Kumar BV,Roopashree SD,Das S,Shankar SK

    更新日期:1992-01-01 00:00:00

  • Babesia bovis: vaccination studies with three groups of high molecular weight antigens from lysate of infected erythrocytes.

    abstract::A void volume fraction and fractions of mean sizes 800 kdalton and 300 kdalton were isolated by gel filtration from lysate of bovine erythrocytes infected with Babesia bovis. All fractions had good serological activity, as assayed by ELISA and IFA. Groups of four splenectomized calves were vaccinated with each fractio...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Waltisbuhl DJ,Goodger BV,Wright IG,Mirre GB,Commins MA

    更新日期:1987-01-01 00:00:00

  • Thelohanellus niloticus sp. nov. (Myxozoa: Myxosporea), a parasite of the Nile carp Labeo niloticus from the River Nile, Egypt.

    abstract::In the present study, the morphology and morphometric characterization of Thelohanellus niloticus sp. nov., a new myxozoan belonging to genus Thelohanellus Kudo, 1933 (Myxosporea, Bivalvulida) infecting the gills of Labeo niloticus (Osteichthyes, Cyprinidae), were described for the first time from the River Nile at El...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Abdel-Ghaffar F,Morsy K,Bashtar AR,El-Ganainy S,Gamal S

    更新日期:2013-01-01 00:00:00

  • Comparative genotyping of Echinococcus granulosus infecting buffalo in Iran using cox1 gene.

    abstract::Twenty-five isolates of Echinococcus granulosus protoscoleces from hydatid cysts were collected from 25 buffaloes in five different provinces of Iran. DNA was extracted from protoscoleces and used for phylogenetical analysis. For this aim, the DNA was amplified using specific primers derived from cox1 gene and, subseq...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Pour AA,Hosseini SH,Shayan P

    更新日期:2011-05-01 00:00:00

  • Zoonotic and genetically diverse subtypes of Blastocystis in US pre-weaned dairy heifer calves.

    abstract::Blastocystis is an emerging zoonotic pathogen with global distribution. However, limited data exist on the prevalence and genetic diversity of Blastocystis in the USA and in food animals. We conducted the first large-scale molecular investigation of Blastocystis in the USA by testing 2539 fecal samples from dairy heif...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Maloney JG,Lombard JE,Urie NJ,Shivley CB,Santin M

    更新日期:2019-02-01 00:00:00

  • Investigations into the production and function of leukotrienes during histotropic development of Oesophagostomum dentatum.

    abstract::The dynamics of production and excretion of leukotrienes by parasitic larvae of Oesophagostomum dentatum and their role for the development of the larvae were studied. Larvae were cultured in vitro to the fourth stage (L4). Leukotriene B4 (LTB4) was detected in homogenates and in supernatant of larvae, with the homoge...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Daugschies A

    更新日期:1996-01-01 00:00:00

  • Effects of sex and age on the susceptibility of C57BL/6J mice to infection with Brachylaima cribbi and the course of infection in NOD SCID mice.

    abstract::The C57BL/6J strain of Mus musculus is susceptible to the terrestrial trematode Brachylaima cribbi. The duration of infection in these mice is generally 9-12 weeks with a peak excretion of eggs at 4 weeks post-infection (wpi). The effects of age and sex on the course of infection were investigated by comparing infecti...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Butcher AR,Palethorpe HM,Grove DI

    更新日期:2002-07-01 00:00:00

  • Use of enzyme-linked immunosorbent assay and enzyme-linked immunoelectrotransfer blot for the diagnosis and monitoring of neurocysticercosis.

    abstract::A total of 70 proven cases of neurocysticercosis from la Réunion (Indian Ocean) were studied with enzyme-linked immunoassay (ELISA) and immunoelectrotransfer blot (EITB) to detect specific antibodies in serum and cerebrospinal fluid (CSF). Absorbance levels of antibody to crude Taenia solium cyst extract as an antigen...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Simac C,Michel P,Andriantsimahavandy A,Esterre P,Michault A

    更新日期:1995-01-01 00:00:00

  • Tackling the growing threat of dengue: Phyllanthus niruri-mediated synthesis of silver nanoparticles and their mosquitocidal properties against the dengue vector Aedes aegypti (Diptera: Culicidae).

    abstract::Mosquitoes are vectors of devastating pathogens and parasites, causing millions of deaths every year. Dengue is a mosquito-borne viral infection found in tropical and subtropical regions around the world. Recently, transmission has strongly increased in urban and semiurban areas, becoming a major international public ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Suresh U,Murugan K,Benelli G,Nicoletti M,Barnard DR,Panneerselvam C,Kumar PM,Subramaniam J,Dinesh D,Chandramohan B

    更新日期:2015-04-01 00:00:00

  • Development of a loop-mediated isothermal amplification (LAMP) and a direct LAMP for the specific detection of Nosema ceranae, a parasite of honey bees.

    abstract::Nosema ceranae is a ubiquitous microsporidian pathogen infecting the midgut of honey bees. The infection causes bee nosemosis, a disease associated with malnutrition, dysentery, and lethargic behavior, and results in considerable economic losses in apiculture. The use of a rapid, sensitive, and inexpensive DNA-based m...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Lannutti L,Mira A,Basualdo M,Rodriguez G,Erler S,Silva V,Gisder S,Genersch E,Florin-Christensen M,Schnittger L

    更新日期:2020-12-01 00:00:00

  • Asian fish tapeworm, Khawia japonensis (Yamaguti, 1934), has expanded its European invasive range.

    abstract::The invasive fish tapeworm, Khawia japonensis (Yamaguti, 1934) originally described in Japan, is reported for the first time in Slovakia. The tapeworm was found in farmed common carp (Cyprinus carpio L.) from East-Slovakian breeding fish pond. This finding is registered 4 years after the first announcement of this par...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Oros M,Barčák D,Bazsalovicsová E,Hanzelová V

    更新日期:2015-05-01 00:00:00

  • Larvicidal activity of lipophilic extract of Hypericum carinatum (Clusiaceae) against Aedes aegypti (Diptera: Culicidae) and benzophenones determination.

    abstract::In this study, the larvicidal activity of an enriched fraction of the major lipophilic phenolic compounds from Hypericum carinatum Griseb. (Clusiaceae) was investigated against larvae of Aedes aegypti (Diptera: Culicidae), the main vector of dengue virus in Brazil. The larval mortality rate ranged 37.33 to 72.00 % at ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: da Silva FC,de Barros FM,Prophiro JS,da Silva OS,Pereira TN,de Loreto Bordignon SA,Eifler-Lima VL,von Poser GL

    更新日期:2013-06-01 00:00:00

  • Cloning, expression, and characterization of Schistosoma japonicum tegument protein phosphodiesterase-5.

    abstract::The tegument proteins of schistosomes are regarded as potential vaccine candidates and drug targets to control schistosomiasis. Nucleotide pyrophosphatase/phosphodiesterase-5 (NPP-5), which belongs to a multigene family of nucleotide pyrophosphatase/phosphodiesterases (NPPs), is important in the hydrolysis of pyrophos...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Zhang M,Han Y,Zhu Z,Li D,Hong Y,Wu X,Fu Z,Lin J

    更新日期:2012-02-01 00:00:00

  • Influence of PF1022A on the motility of Angiostrongylus cantonensis in vitro.

    abstract::Our previous in vivo studies on angiostrongyliasis showed that PF1022A had stronger killing effects against female adults than against males. No killing effects were observed against young adult worms in the central nervous system. To characterize the former in vivo action of PF1022A, in vitro effects of PF1022A on th...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Kachi S,Terada M,Hashimoto H

    更新日期:1997-01-01 00:00:00

  • Morphological response of triclabendazole-susceptible and triclabendazole-resistant isolates of Fasciola hepatica to treatment in vitro with nitroxynil (Trodax).

    abstract::Adult liver flukes belonging to three isolates of differing sensitivity to triclabendazole were incubated for 24 h in vitro in nitroxynil at a concentration of 100 microg/ml. Fine structural changes to the tegument, sub-tegumental region and gut were assessed by transmission electron microscopy. Similar changes were o...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: McKinstry B,Halferty L,Brennan GP,Fairweather I

    更新日期:2009-02-01 00:00:00

  • Plasmodium helical interspersed subtelomeric family-an enigmatic piece of the Plasmodium biology puzzle.

    abstract::Plasmodium falciparum (Pf) refurbishes the infected erythrocytes by exporting a myriad of parasite proteins to the host cell. A novel exported protein family 'Plasmodium Helical Interspersed Subtelomeric' (PHIST) has gained attention for its significant roles in parasite biology. Here, we have collected and analysed a...

    journal_title:Parasitology research

    pub_type: 杂志文章,评审


    authors: Kumar V,Behl A,Sharma R,Sharma A,Hora R

    更新日期:2019-10-01 00:00:00

  • Haemosporidian parasites of resident and wintering migratory birds in The Bahamas.

    abstract::In temperate regions, some avian haemosporidian parasites have evolved seasonal transmission strategies, with chronic infections relapsing during spring and transmission peaking during the hosts' breeding season. Because lineages with seasonal transmission strategies are unlikely to produce gametocytes in winter, we p...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Soares L,Young EI,Ricklefs RE

    更新日期:2020-05-01 00:00:00

  • Novel Cryptosporidium bat genotypes III and IV in bats from the USA and Czech Republic.

    abstract::Bats from the families Rhinolophidae (n = 90) and Vespertilionidae (n = 191) in the USA and Czech Republic were screened for the presence of Cryptosporidium by microscopic and molecular analysis of faecal samples collected from rectum of dissected animals and from the ground beneath roosting sites. Cryptosporidium ooc...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Kváč M,Hořická A,Sak B,Prediger J,Salát J,Širmarová J,Bartonička T,Clark M,Chelladurai JR,Gillam E,McEvoy J

    更新日期:2015-10-01 00:00:00

  • Immunopathological assessments of human Blastocystis spp. in experimentally infected immunocompetent and immunosuppresed mice.

    abstract::Blastocystis spp., one of the most common parasites colonizing the human intestine, is an extracellular, luminal protozoan with controversial pathogenesis. The host's immune response against Blastocystis spp. infection has also not been defined yet. Therefore, this research aimed to assess the potential pathogenicity ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Abdel-Hafeez EH,Ahmad AK,Abdelgelil NH,Abdellatif MZ,Kamal AM,Hassanin KM,Abdel-Razik AR,Abdel-Raheem EM

    更新日期:2016-05-01 00:00:00

  • Inhibitory effect of allicin on the growth of Babesia and Theileria equi parasites.

    abstract::Allicin is an active ingredient of garlic that has antibacterial, antifungal, antiviral, and antiprotozoal activity. However, the inhibitory effects of allicin on Babesia parasites have not yet been examined. In the present study, allicin was tested as a potent inhibitor against the in vitro growth of bovine and equin...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Salama AA,AbouLaila M,Terkawi MA,Mousa A,El-Sify A,Allaam M,Zaghawa A,Yokoyama N,Igarashi I

    更新日期:2014-01-01 00:00:00

  • Could ivermectin have a synergic effect with albendazole in hydatidosis therapy?

    abstract::The efficacy of a combination of ivermectin (IVM) and albendazole (ABZ) used as a chemoprophylactic treatment and as treatment of secondary hydatidosis is described for the first time. IVM treatment alone was not effective against Echinococcus granulosus, either when the protoscolices were recently inoculated or when ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Moreno MJ,Casado N,Urrea-París MA,Rodríguez-Caabeiro F

    更新日期:2002-06-01 00:00:00

  • The effect of tunicamycin and monensin on the association of Trypanosoma cruzi with resident macrophages.

    abstract::The effect of incubation of parasites (epimastigote and trypomastigote forms of Trypanosoma cruzi) or macrophages in the presence of tunicamycin (TM) or monensin (M) on the parasite-macrophage association was analysed. Treatment of the parasites with TM, a drug which interferes with the process of N-glycosylation of p...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Souto-Padrón T,de Souza W

    更新日期:1989-01-01 00:00:00

  • The effects of interleukin (IL)-12 and IL-4 deficiency on worm development and granuloma formation in Schistosoma japonicum-infected mice.

    abstract::CD4(+) T-helper (Th) cell is widely recognized to be capable of influencing worm development and egg granuloma formation after schistosome infection. Interleukin (IL)-12 and IL-4 play key roles in regulation of Th cell differentiation. In the present study, we subcutaneously inoculated mice with hybridoma cells secret...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Cheng YL,Song WJ,Liu WQ,Lei JH,Kong Z,Li YL

    更新日期:2012-01-01 00:00:00

  • Liver response of rabbits to Eimeria coecicola infections.

    abstract::Intestinal coccidiosis of rabbits induced by E. coecicola causes enormous economic losses in rabbit farms. Here, we investigate the effect of E. coecicola on the liver of the rabbit Oryctolagus cuniculus. On day 7 p.i., fecal expulsion of E. coecicola oocysts is maximal and rabbits have lost approximately 25% of their...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Al-Quraishy S,Metwaly MS,Dkhil MA,Abdel-Baki AA,Wunderlich F

    更新日期:2012-02-01 00:00:00

  • Meta-analysis of the diagnostic efficiency of the questionnaires screening for schistosomiasis.

    abstract::Schistosomiasis is the second widespread tropical disease that affects the health of over 240 million people of 78 countries. Questionnaires have been commonly used to diagnose schistosomiasis, while no meta-analysis of their efficacy had been reported previously. This meta-analysis was conducted to assess their diagn...

    journal_title:Parasitology research

    pub_type: 杂志文章,meta分析


    authors: Yang F,Tan XD,Liu B,Yang C,Ni ZL,Gao XD,Wang Y

    更新日期:2015-09-01 00:00:00

  • Ultrastructure of a Sarcocystis sp. infecting skinks of the genus Agama.

    abstract::Macroscopically visible sarcocysts were observed in the skeletal muscles of naturally infected skinks of the genus Agama (infection rate 11.3%). Sarcocysts were described by means of transmission electron microscopy. These cysts measured 0.03-0.25 x 0.38-1.7 mm (mean 0.12 x 1.1 mm). Typical mature cysts were bordered ...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Sakran TF

    更新日期:2000-09-01 00:00:00

  • Clinical, laboratory and pathological findings in cats experimentally infected with Aelurostrongylus abstrusus.

    abstract::Aelurostrongylus abstrusus parasitizes the respiratory tract and can heavily affect the breathing and general condition of cats. Experimental infections of six cats were initiated by intragastric administration with 100 or 800 third-stage larvae (L3) obtained from the terrestrial snail Helix aspersa. First-stage larva...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Schnyder M,Di Cesare A,Basso W,Guscetti F,Riond B,Glaus T,Crisi P,Deplazes P

    更新日期:2014-04-01 00:00:00

  • Factors affecting the component community structure of haemoparasites in common voles ( Microtus arvalis) from the Mazury Lake District region of Poland.

    abstract::The prevalence and abundance of infections with haemoparasites were studied over a 4-year period in Microtus arvalis (common vole, n =321) sampled from fallow grassland sites in north-eastern Poland. Total species richness was five (prevalence= Haemobartonella sp. 63.9%, Bartonella spp. 27.7%, Babesia microti 9.0%, Tr...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Pawelczyk A,Bajer A,Behnke JM,Gilbert FS,Sinski E

    更新日期:2004-03-01 00:00:00

  • Immunoblot for the detection of Ascaris suum-specific antibodies in patients with visceral larva migrans (VLM) syndrome.

    abstract::Visceral larva migrans (VLM) syndrome caused by Toxocara canis larvae was first described in the 1950s. The role of other nematode larvae, i.e. the pig roundworm Ascaris suum as a causative agent of visceral larva migrans-associated symptoms like general malaise, cough, liver dysfunction, hypereosinophilia with hepato...

    journal_title:Parasitology research

    pub_type: 杂志文章


    authors: Schneider R,Obwaller A,Auer H

    更新日期:2015-01-01 00:00:00