Abstract：
:This experimental study on pigs was designed to simulate natural, long-term exposure to Ascaris suum under modern management conditions. Parasite kinetics were followed in pigs receiving A. suum eggs as repeated trickle inoculations at two dose levels beginning at a body weight of 25 kg until their slaughter at 90 kg (baconers). In pigs inoculated twice weekly with 500 eggs, there was an initial marked rise in the numbers of hepatic milk spots, but as early as around week 6 after the start of inoculations and until week 16, at which time the last pigs were slaughtered, the numbers of spots diminished drastically. In pigs receiving only 25 eggs twice weekly, low and moderately fluctuating numbers of spots were seen throughout the experiment. Larvae recoverable from the livers and lungs were observed mainly during the beginning of the experiment. Before patency, immature intestinal worms were found in moderate numbers that showed a rough positive correlation with the dose levels, but at the time at which adult worms started to appear, immature parasites could practically no longer be found. In all, only 10 of 40 pigs harbored adults, and 4 of these 10 pigs harbored 80% of the total worm population. The results show that acquired dose-dependent host responses to A. suum play an important role in regulating the worm population along the migratory route of the parasite and that the final burden of worms in the small intestine is dose-dependent and highly variable.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Eriksen L,Nansen P,Roepstorff A,Lind P,Nilsson Odoi
10.1007/BF00931733subject
Has Abstractpub_date
1992-01-01 00:00:00pages
241-6issue
3eissn
0932-0113issn
1432-1955journal_volume
78pub_type
杂志文章abstract：:Cytokine responses of lymphocytes against Toxoplasma gondii are usually studied by stimulating the cells from infected animals with tachyzoite lysate antigens (TLA) in vitro. We examined whether strains (genotypes) of the parasite used for TLA affect the production of IL-2, IL-4, IL-10 and IFN-gamma in the culture of ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1416-5
更新日期：2005-10-01 00:00:00
abstract：:Investigation with light and electron microscopy has been made of the cement apparatus of the mature male Neoechinorhynchus rutili, a parasite of Gasterosteus aculeatus. N. rutili possesses a single compact mass of glandular tissue (cement gland) with eight giant nuclei. The nucleus is lobe-shaped and has a conspicuou...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360000248
更新日期：2000-10-01 00:00:00
abstract：:Plasmodium berghei XAT is an irradiation-induced, permanent attenuated derivative from high-virulence P. berghei NK65. Monoclonal antibodies against XAT were developed. By immunofluorescence screening, one monoclonal antibody was identified that was reactive with XAT at the schizont stage but not with NK65 nor with an...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00535143
更新日期：1988-01-01 00:00:00
abstract：:Hepatozoon aegypti Bashtar, Boulos & Mehlhorn, 1984 was first described from the blood of the diadem snake (Spalerosophis diadema) in Egypt. During an investigation of the diversity of reptilian haemogregarines in Saudi Arabia, seven diadem snakes (100% of the sample) were found to be highly parasitised by H. aegypti,...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6006-4
更新日期：2018-10-01 00:00:00
abstract：:Water buffalo is important livestock in several countries in the Latin American and Caribbean regions. This buffalo species can be infected by tick-borne hemoparasites and remains a carrier of these pathogens which represent a risk of infection for more susceptible species like cattle. Therefore, studies on the epidem...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-06194-6
更新日期：2019-03-01 00:00:00
abstract：:Common helminth infections promote Th2-skewed immune responses in their hosts. We have studied the role of intact carbohydrate structures on Taenia crassiceps compounds in the induction of biased type 2 and anti-inflammatory immune responses on peptide-stimulated T cells by using DO11.10 transgenic (OVA Tg) mice. Whil...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0159-2
更新日期：2006-09-01 00:00:00
abstract：:Biomphalaria glabrataembryonic (Bge) cells have been shown to provide favourable environmental conditions for the development of Schistosoma mansoni sporocysts. We investigated the effect of Bge excretory-secretory products on metabolic activity and gene transcription in S. mansoni mother sporocysts. Using the differe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0643-2
更新日期：2003-01-01 00:00:00
abstract：:Due to the global health problems associated with mosquito-borne diseases, over two million people primarily in the tropical countries are at risk. The widely and commonly used chemical method though effective, has some major disadvantages making insect control practically difficult. In view of the above, it is unavoi...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2261-3
更新日期：2011-08-01 00:00:00
abstract：:Discoid granules were isolated from the tegument of adult Schistosoma mansoni by differential centrifugation of freeze-thaw extracts. Comparison of proteins and glycoproteins from discoid granules, surface membranes and the soluble fraction implied that discoid granules and the surface membrane were functionally linke...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00539573
更新日期：1988-01-01 00:00:00
abstract：:We examined the in vitro effect of increasing gliotoxin concentrations on the infectivity of Toxoplasma gondii for NIH-3T3 murine fibroblasts and on Toxoplasma chymotrypsin-like activity, which is specific to the proteasome. Parasite penetration of host cells was not modified by a high gliotoxin concentration (1 micro...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0644-1
更新日期：2002-08-01 00:00:00
abstract：:cDNA clones for homologues of a molecular chaperone of the endoplasmic reticulum called the immunoglobulin heavy-chain binding protein (BiP) have been isolated from Eimeria maxima and E. tenella sporozoite cDNA libraries. The E. tenella cDNA clone is of full length and has a predicted N-terminal signal sequence of app...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050163
更新日期：1996-01-01 00:00:00
abstract：:Maturation of trematode larval stages is expected to be temporally and spatially adapted to maximise the encounter with the adequate downstream host, i.e. the host, which will be infected by this parasite stage. Since studies on intramolluscan parasite maturation are scarce but important in the context of parasite tra...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4774-7
更新日期：2016-02-01 00:00:00
abstract：:The ethanolic leaf extract of Cassia obtusifolia was investigated for their larvicidal and oviposition deterrence effects against Anopheles stephensi. Concentrations ranging from 25 to 125 mg/l were assessed at 24 h post-treatment against late third instar larvae. The leaf extract had significant larvicidal effect wit...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1197-8
更新日期：2009-01-01 00:00:00
abstract：:Adult liver flukes belonging to three isolates of differing sensitivity to triclabendazole were incubated for 24 h in vitro in nitroxynil at a concentration of 100 microg/ml. Fine structural changes to the tegument, sub-tegumental region and gut were assessed by transmission electron microscopy. Similar changes were o...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1241-8
更新日期：2009-02-01 00:00:00
abstract：:Trichomonas gallinae are parasitic flagellates of importance in wild and domestic birds. The parasite is worldwide distributed, and Columbine birds are its main host. Current research focuses mostly on epidemiological and phylogenetic studies. However, there is still a lack of knowledge regarding parasite-host interac...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06887-x
更新日期：2020-11-01 00:00:00
abstract：:The chemotherapy of visceral leishmaniasis (VL) has several limitations including resistance and toxicity of the existing drugs. Downregulation of immune system further aggravates the problems. To combat this situation, leishmanicidal efficacy of already marketed standard antifungal drug, fluconazole under the approac...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-2230-2
更新日期：2011-04-01 00:00:00
abstract：:Myiasis refers to the infestation of living humans and vertebrates with fly larvae that feed on necrotic or vital tissue of the host. Since the invasion of new fly species in Europe is currently being observed, which live obligatorily parasitically or are close relatives of such species, the aim of this study is to ob...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6145-7
更新日期：2019-02-01 00:00:00
abstract：:Precise identification of avian schistosomes in the genus Trichobilharzia at the species level is difficult and requires both traditional morphological and molecular techniques. To obtain satisfactory results by traditional methods, the characteristics of the intact adults or large fragments of male and females are ne...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-019-06573-7
更新日期：2020-03-01 00:00:00
abstract：:The induction of protective immunity to Leishmania amazonensis was investigated by injection of parasite clones of low and medium virulence into susceptible mice. To this end, L. amazonensis were cloned by limiting dilution and the clones' virulence was evaluated by the course of infection in susceptible mice. Clones ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050321
更新日期：1997-01-01 00:00:00
abstract：:Hymenolepis diminuta is a zoonotic cestode parasitizing the small intestine of rodents (definitive hosts). Humans can accidentally enter into the life cycle of this tapeworm via the ingestion of infected insects (intermediate hosts) containing cestode cysticercoids in their body cavity. More than two centuries after t...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-020-06663-x
更新日期：2020-07-01 00:00:00
abstract：:This paper reports the efficacy of a novel flavoured tablet formulation of emodepside plus praziquantel (Profender tablets for dogs) against mature and immature adult hookworms (Ancylostoma caninum and Uncinaria stenocephala) in dogs. The tablets were used at the minimum recommended dose of 1 mg emodepside and 5 mg pr...
journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00436-009-1490-1
更新日期：2009-08-01 00:00:00
abstract：:Ultrastructure of Fibrillaspora is highly similar to that of Berwaldia but the former is phylogenetically distant from the taxon annotated as Berwaldia schaefernai (Genbank accession # AY090042). It was shown recently, however, that the latter sequence was not derived from Berwaldia, and correct nucleotide sequence da...
journal_title：Parasitology research
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00436-018-5786-x
更新日期：2018-04-01 00:00:00
abstract：:Previous studies have shown that excretory/secretory products of larval Taenia crassiceps have immunomodulatory activities. We report here that one of these products, termed p66, possesses activities that mimic some characteristics of murine interferon-gamma (IFN-gamma). Purified p66 cross-reacts with anti-murine IFN-...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-002-0590-y
更新日期：2002-05-01 00:00:00
abstract：:Ticks can significantly affect the health and fitness of the host. Seasonal population dynamics of ticks play a vital role in disease transmission and the shaping of life-history traits of both tick and host. In this study, we examine the seasonal population dynamics of Ixodes hirsti in South Australia. For 2 years, w...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1071-8
更新日期：2008-09-01 00:00:00
abstract：:Excretory/secretory (ES) products collected from exsheathed L3 or parasitic stages of Haemonchus contortus were tested in vitro for gastrin stimulatory properties using an ovine abomasal antral mucosal preparation. In addition, the motility of exsheathed L3 and parasites recovered on weeks 2, 6 and 8 post-infection wa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1274-6
更新日期：2005-01-01 00:00:00
abstract：:The purified metalloprotease and the partially purified cysteine protease from pathogenic Cryptobia salmositica were characterized. Using haemoglobin gel electrophoresis, we detected five enzymatic bands in crude parasite lysate; one protease (200 kDa) yielded a metalloprotease band and other four, cysteine protease b...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050435
更新日期：1998-06-01 00:00:00
abstract：:Infection in dogs and humans with the protozoan parasite Leishmania are widespread in tropical and subtropical countries around the globe. Sand flies of the order Phlebotomus in the Old World and Lutzomyia in the New World function as the vector of this disease. In dogs, skin lesions are the most prominent signs of ca...
journal_title：Parasitology research
pub_type： 临床试验,杂志文章
doi：10.1007/s00436-003-0905-7
更新日期：2003-07-01 00:00:00
abstract：:Mastomys coucha and jirds infected with Acanthocheilonema viteae, a filarial species free of endosymbiontic bacteria of the genus Wolbachia, suffer lethal side effects after effective microfilaricidal therapy with diethylcarbamazine and levamisole, whereas, M. coucha infected with the Wolbachia-infested species Brugia...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-005-1386-7
更新日期：2005-10-01 00:00:00
abstract：:Taenia species of domestic dogs can cause cysticercosis and coenurosis in a wide range of intermediate hosts including humans. Most taeniids of dogs are globally distributed, but some wildlife-transmitted species can be specific for certain regions. Generally, little information exists on the species composition and f...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06793-2
更新日期：2020-09-01 00:00:00
abstract：:A majority of Kudoa spp. infects the somatic muscle of fish establishing cysts. Previously, elevated humoral responses were detected in BALB/c mice immunised with Kudoa sp. pseudocyst extracts and in BALB/c mice orally inoculated with Kudoa sp. pseudocysts, as well as the presence of anti-Kudoa sp. antibodies in human...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-008-1017-1
更新日期：2008-08-01 00:00:00
