Abstract：
:We have previously reported the involvement of cyclic AMP in regulating flagellar waveforms in Leishmania. Here, we investigated the roles of calcium, calmodulin, and calcineurin in flagellar motility regulation in L. donovani. Using high-speed videomicroscopy, we show that calcium-independent calmodulin and calcineurin activity is necessary for motility in Leishmania. Inhibition of calmodulin and calcineurin induced ciliary beats interrupting flagellar beating in both live (in vivo) and ATP-reactivated (in vitro) parasites. Our results indicate that signaling mediated by calmodulin and calcineurin operates antagonistically to cAMP signaling in regulating the waveforms of Leishmania flagellum. These two pathways are possibly involved in maintaining the balance between the two waveforms, essential for responding to environmental cues, survival, and infectivity.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
Mukhopadhyay AG,Dey CSdoi
10.1007/s00436-017-5608-6subject
Has Abstractpub_date
2017-11-01 00:00:00pages
3221-3228issue
11eissn
0932-0113issn
1432-1955pii
10.1007/s00436-017-5608-6journal_volume
116pub_type
杂志文章abstract：:Gross anatomy of muscle and sensory/motor innervation of adult and intramolluscan developmental stages of Echinostoma caproni have been investigated to ascertain the organisation and the functional correlates of any stage-specific patterns of staining. Using indirect immunocytochemistry to demonstrate neuroactive subs...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1120-x
更新日期：2004-06-01 00:00:00
abstract：:The phylogenetic placement of gregarine parasites (Apicomplexa: Gregarinasina) within the Apicomplexa was derived by comparison of small-subunit ribosomal RNA gene sequences. Gregarine sequences were obtained from Gregarina niphandrodes Clopton, Percival, and Janovy, 1991, and Monocystis agilis Stein, 1848 (Eugregarin...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050655
更新日期：1999-11-01 00:00:00
abstract：:Flame atomic absorption spectrometry was performed to determine the alteration of calcium concentration in the soft parts and shells of Biomphalaria alexandrina and Bulinus truncatus due to the infection with Schistosoma mansoni and S. haematobium, respectively. The results showed significant lowering in the calcium c...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-007-0566-z
更新日期：2007-09-01 00:00:00
abstract：:Plasmodium berghei XAT is an irradiation-induced, permanent attenuated derivative from high-virulence P. berghei NK65. Monoclonal antibodies against XAT were developed. By immunofluorescence screening, one monoclonal antibody was identified that was reactive with XAT at the schizont stage but not with NK65 nor with an...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00535143
更新日期：1988-01-01 00:00:00
abstract：:Ultrastructural characters of the spermiogenesis and mature spermatozoon of Notopentorchis sp. (Cestoda, Cyclophyllidea, Paruterinidae), a parasite from Apus affinis (Aves, Apodiformes, Apodidae) from Gabon, are described by means of transmission electron microscopy. Cytochemical analysis for detection of glycogen was...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2809-2
更新日期：2012-07-01 00:00:00
abstract：:Over a 4-year period, we analyzed 128 fecal samples from free-living elk (Alces alces L., 1758) to determine the prevalence of Eimeria infections and identify the species present. Two eimerian species were isolated including Eimeria alces and a morphotype resembling Eimeria catubrina. Overall, two samples from 128 sam...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3262-6
更新日期：2013-05-01 00:00:00
abstract：:The value profiles of 5 intracellular enzymes, 15 metabolites (with 2 associated ratios), and 3 electrolytes were monitored over time in 9 captive-reared African black-footed penguins (Spheniscus demersus) with different avian malaria clinical status: uninfected, subclinically infected, and clinically infected with fa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931537
更新日期：1995-01-01 00:00:00
abstract：:Head lice infestation (HLI) caused by Pediculus humanus capitis has been a public health problem worldwide. Specially designed combs are used to identify head lice, while anti-lice products are applied on the scalp for treatment. In the present study, we aimed to test whether combing only by precision detection comb (...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4311-8
更新日期：2015-04-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050106
更新日期：1996-01-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-011-2670-3
更新日期：2011-12-01 00:00:00
abstract：:The impact of parasites on host population dynamics depends on local abundance of the parasites, which may vary considerably across spatial scales. In sand hopper populations, mermithid parasites have major impacts on host dynamics, which may vary among spatially separated populations due to the sand hopper's wide, pa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-4254-5
更新日期：2015-03-01 00:00:00
abstract：:Schistosomiasis seriously affects human health in tropical regions. Its prevention is more important than treatment, raising the need for effective control methods. Recently, the role of nanomaterials in medical science has been growing. The present study aimed to evaluate the potential effects of silver (Ag) and gold...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-6093-2
更新日期：2018-12-01 00:00:00
abstract：:Among the topics related to invasion science, the least studied are parasite co-introduction and spillback. This leads to an uncertainty in invasion ecology theories and applications to management. Therefore, the present study brings a systematic review of published information on the metazoan parasite fauna of Microp...
journal_title：Parasitology research
pub_type： 杂志文章,评审
doi：10.1007/s00436-018-5876-9
更新日期：2018-06-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-004-1250-1
更新日期：2005-02-01 00:00:00
abstract：:In urban environments, catch basins serve as major developmental and resting sites for anthropophilic and zoophilic mosquitoes. However, the use of this habitat is inconsistent, with abundance of larvae varying significantly across catch basins at a fine spatial scale. During seasonal summer investigations on mosquito...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-016-4912-x
更新日期：2016-04-01 00:00:00
abstract：:The polymerase chain reaction (PCR) assay has turned out to be one of the most potential tools for diagnosis of schistosomiasis. However, the source and metabolic dynamics of Schistosoma japonicum DNA in the blood of hosts is not clear. In this study, rabbit models with monosexual and mixed sexual cercariae infection ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-012-3115-3
更新日期：2013-01-01 00:00:00
abstract：:This study is focused on the feasibility of two treatments of alcohol-fixed monogenean parasites which are intended to be use for the combined morphological and molecular characterizations. The monogenean parasite, Eudiplozoon nipponicum, was selected as a model parasite species; however it is expected that these tech...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-010-1949-0
更新日期：2010-09-01 00:00:00
abstract：:Topical application and intraperitoneal administration of spiroarsoranes were carried out to cure central nervous system (CNS) trypanosomiasis in the chronic Trypanosoma brucei GVR 35 mouse model. Topical application appeared more efficient than intraperitoneal injection. The periods of aparasitaemia after treatment w...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s004360050148
更新日期：1996-01-01 00:00:00
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journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2775-8
更新日期：2012-06-01 00:00:00
abstract：:Proteins of Babesia equi piroplasms were characterized. The piroplasms of B. equi were purified by lysis of infected horse erythrocytes with N2 gas cavitation followed by separation in Percoll density-gradient centrifugation. The relative molecular weights (Mr) of major proteins separated by two-dimensional sodium dod...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00932505
更新日期：1993-01-01 00:00:00
abstract：ABTRACT:Structure of the helminth community of Megaleporinus obtusidens collected in Lake Guaíba was evaluated, and the results indicated that the diversity of helminth species was probably determined by fish behavior and eating habits. The influence of sex, weight, and standard length of hosts for parasitic indices wa...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-018-5933-4
更新日期：2018-08-01 00:00:00
abstract：:The efficacy of emodepside plus toltrazuril (Procox® oral suspension for dogs) against different species of gastrointestinal nematodes (Toxocara canis, Ancylostoma caninum, Uncinaria stenocephala) was evaluated in nine randomised,blinded and placebo-controlled laboratory studies in naturally or experimentally infected...
journal_title：Parasitology research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00436-011-2397-1
更新日期：2011-08-01 00:00:00
abstract：:Amoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments. The aim of this study is to evaluate the in vitro amoebicidal activity of the methanolic extracts of Satureja cuneifolia and Melissa officinalis. In th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-011-2744-2
更新日期：2012-06-01 00:00:00
abstract：:The first description of an electron microscopic study of Trypanosoma corvi in the vector Ornithomyia avicularia is reported. There is a close association between vector and parasite in the midgut, ileum and rectum of the vector. The midgut distribution of parasites is determined by the peritrophic membrane, which con...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/BF00931269
更新日期：1989-01-01 00:00:00
abstract：:Toxoplasma gondii is a parasite which can be transmitted to humans via the consumption of contaminated meat products derived from different animal species, e.g., poultry. In Europe, the consumption rate of poultry meat is high and may pose a risk for humans. However, little is known about the prevalence and immune res...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-014-3788-x
更新日期：2014-04-01 00:00:00
abstract：:The present paper reports the ability of egg-propagated gametocyte vaccine to induce protective immunity against Eimeria tenella infections in offspring chicks. For this purpose, breeding hens were immunized with adjuvanted gametocyte vaccine orally, being the best vaccine in our previous studies. Eggs collected 2 wee...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-006-0382-x
更新日期：2007-04-01 00:00:00
abstract：:Multiple schistosome and soil-transmitted nematode infections are frequently reported in human populations living in tropical areas of developing countries. In addition to exposure factors, the host immune response plays an important role in helminth control and morbidity in hosts with multiple infections; however, th...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-015-4706-6
更新日期：2015-12-01 00:00:00
abstract：:During a survey lasting from 1990 to 2008, we captured 4,113 Asian house rats, Rattus tanezumi Temminck 1844 (Rodentia: Muridae) from 28 counties of Yunnan Province in southwestern China. From these rats, a total of 19,304 gamasid mites (Acari: Mesostigmata) were collected and identified as comprising 50 different spe...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-013-3354-y
更新日期：2013-05-01 00:00:00
abstract：:Addressing the problems linked to tsetse-transmitted trypanosomiases requires considerable data on tsetse distribution and trypanosome infections. Although efforts to map tsetse and trypanosome infections have been undertaken at continental level, published data are still rare in wildlife reserves of West and Central ...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-020-06606-6
更新日期：2020-03-01 00:00:00
abstract：:Tetratrichomonas didelphidis is a flagellate protozoan found in the intestine of the opossum. The parasite lives in a hostile and stressed environment, where it interacts with microorganisms and can survive under extreme conditions for growth, involving strict anaerobiosis or equilibration with air and abundance or ab...
journal_title：Parasitology research
pub_type： 杂志文章
doi：10.1007/s00436-003-1015-2
更新日期：2004-01-01 00:00:00
