Abstract:
:Multiple schistosome and soil-transmitted nematode infections are frequently reported in human populations living in tropical areas of developing countries. In addition to exposure factors, the host immune response plays an important role in helminth control and morbidity in hosts with multiple infections; however, these aspects are difficult to evaluate in human populations. In the current study, female Swiss mice were simultaneously co-infected with Strongyloides venezuelensis and Schistosoma mansoni or infected with St. venezuelensis at 2, 4, or 14 weeks after Sc. mansoni infection. The simultaneously infected mice showed a similar parasite burden for St. venezuelensis compared with mono-infected mice. In contrast, there was a significant reduction of St. venezuelensis burden (primarily during the migration of the larvae) in mice that were previously infected with Sc. mansoni at the acute or chronic phase. Independent of the stage of Sc. mansoni infection, the St. venezuelensis co-infection was capable of inducing IL-4 production in the small intestine, increasing the IgE concentration in the serum and increasing eosinophilia in the lungs and intestine. This result suggests that the nematode infection stimulates local type 2 immune responses independently of the schistosomiasis stage. Moreover, previous Sc. mansoni infection stimulated early granulocyte infiltration in the lungs and trematode-specific IgM and IgG1 production that recognized antigens from St. venezuelensis infective larvae; these immune responses would act in the early control of St. venezuelensis larvae. Our data suggest that the effect of multiple helminth infections on host susceptibility and morbidity largely depends on the species of parasite and the immune response.
journal_name
Parasitol Resjournal_title
Parasitology researchauthors
de Rezende MC,Araújo ES,Moreira JM,Rodrigues VF,Rodrigues JL,Pereira CA,Negrão-Corrêa Ddoi
10.1007/s00436-015-4706-6subject
Has Abstractpub_date
2015-12-01 00:00:00pages
4601-16issue
12eissn
0932-0113issn
1432-1955pii
10.1007/s00436-015-4706-6journal_volume
114pub_type
杂志文章abstract::Whole sequencing of protozoan trypanosomatid genomes revealed the presence of several predicted unknown genes coding for hypothetical proteins. Pairwise, alignment-based, computational methods available online are unable to identify the function of these sequences. To detect clues to identify the function of hypotheti...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-005-0064-0
更新日期:2006-03-01 00:00:00
abstract::Phalloidin fluorescence technique, enzyme cytochemistry and immunocytochemistry in conjunction with confocal scanning laser microscopy have been used for the first time to describe the nervous and muscle systems of the viviparous monogenean gill parasite, Macrogyrodactylus clarii. The gross spatial arrangement of musc...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1198-1
更新日期:2004-10-01 00:00:00
abstract::Amoebic keratitis is difficult to treat without total efficacy in some patients because of cysts, which are less susceptible than trophozoites to the usual treatments. The aim of this study is to evaluate the in vitro amoebicidal activity of the methanolic extracts of Satureja cuneifolia and Melissa officinalis. In th...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2744-2
更新日期:2012-06-01 00:00:00
abstract::Epidemiological data and a unique phylogenetic position had suggested that Sarcocystis ovalis in moose and red deer might use a definitive host other than canids, felids, or humans. Corvid birds and rats were therefore evaluated as potential definitive hosts for this species in a small pilot study. Four laboratory rat...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-2017-5
更新日期:2010-11-01 00:00:00
abstract::To determine the prevalence of endoparasites and their association with diarrhea, a survey was conducted in the Southern Province of Zambia that used conventional and molecular techniques applied to stool and urine samples from school-age children (n = 93). Almost half of the stools (49.5%) were diarrhetic. The overal...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-005-0003-0
更新日期:2005-12-01 00:00:00
abstract::The present study aimed to isolate and genotype strains of T. gondii from pigs slaughtered for human consumption in South Brazil. Blood and tissues (heart, diaphragm, liver, tongue, and masseter) from 400 animals were collected at two slaughterhouses. Sera were obtained, and antibodies against T. gondii were detected ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06274-1
更新日期:2019-05-01 00:00:00
abstract::Ingestion of the larval nematode Angiostrongylus cantonensis can cause the human eosinophilic meningitis known as angiostrongyliasis. Analysis of the extracts and excretory-secretory (ES) products of A. cantonensis larvae and adult stages on gelatin substrate zymography demonstrated the presence of distinct gelatinoly...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-005-1484-6
更新日期:2005-12-01 00:00:00
abstract::Monogamy is a mating system with pairs made of only one male and only one female. But social monogamy cannot inevitably imply the sexual exclusivity between mates, which is yet the case in genetic monogamy on which the offspring results only from the observed pair. The genetic monogamy is today considered as an except...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-008-1225-8
更新日期:2009-01-01 00:00:00
abstract::We have identified the 2-Cys peroxiredoxin (Prx) from a bovine Babesia parasite, B. bovis. Prx is a recently described family of antioxidant enzymes that are highly conserved in eukaryotes and prokaryotes. B. bovis 2-Cys Prx (BbTPx-1) contained two conserved cysteine residues that corresponded to Cys47 and Cys170 of t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1587-6
更新日期:2009-10-01 00:00:00
abstract::In latest years, the importance of the Melaleuca alternifolia essential oil (EO) has been greatly empathised due to its anti-microbial and anti-inflammatory effects, as well as to its toxic properties towards many arthropods of great medical and veterinary importance. In this research, the EO extracted from aerial par...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3651-5
更新日期:2014-01-01 00:00:00
abstract::The immunoreactivity of Taenia saginata and T. crassiceps metacestode neutral glyco(sphingo)lipids towards IgG antibodies derived from the sera of calves with experimental cysticercosis has been established. The glyco(sphingo)lipids are separable by normal-phase HPTLC (high-performance thin-layer chromatography) into ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00932412
更新日期:1995-01-01 00:00:00
abstract::Due to the global health problems associated with mosquito-borne diseases, over two million people primarily in the tropical countries are at risk. The widely and commonly used chemical method though effective, has some major disadvantages making insect control practically difficult. In view of the above, it is unavoi...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2261-3
更新日期:2011-08-01 00:00:00
abstract::Hepatic enzymes and biochemical parameter values were analysed in the sera of 32 lambs: 12 infected with 1,000 Dicrocoelium dendriticum metacercariae, 12 with 3,000 and eight controls. Blood samples were collected at intervals of 30 days from day 0 post-infection (p.i.). Half the lambs in each group were slaughtered o...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-004-1128-2
更新日期:2004-08-01 00:00:00
abstract::The ultrastructure of alpha-bacteroids in relation to the fat-body cells of the lantern bug Pyrops candelaria was described. The fat-body-cell cytoplasm contained numerous mitochondria, rough endoplasmic reticula, vacuoles, and storage granules. Its nucleus had scattered chromatin materials. The alpha-bacteroid was en...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s004360050287
更新日期:1997-01-01 00:00:00
abstract::This study was conducted to identify genetic characteristics of Besnoitia spp. isolated from goat in Iran. Molecular analysis of two portions of nuclear ribosomal DNA (ITS1 and ITS2) was used for the genetic characterization of the Besnoitia species. Comparison of the sequencing data of the Iranian Besnoitia samples o...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-2107-4
更新日期:2011-03-01 00:00:00
abstract::This study aimed to compare the sensitivity of five diagnostic methods commonly used for the detection of Toxoplasma gondii in tissues of naturally infected pigs. We purchased 20 heads of pigs in butcher shops in the city of Ilhéus, Bahia. Brain and tongue fragments were taken from each animal for the performance of P...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-011-2514-1
更新日期:2012-02-01 00:00:00
abstract::In freshwater ecosystems, snails can significantly influence the competition between primary producers through grazing of periphyton. This activity can potentially be modified by trematodes, a large group of parasites which mostly use molluscs as the first intermediate host. Available studies, however, show contradict...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-018-6052-y
更新日期:2018-11-01 00:00:00
abstract::This study aims to observe the histopathological alterations in schistosomula of Schistosoma japonicum induced by mefloquine. Mice were infected with S. japonicum cercariae, and after 14 days, a single dose of mefloquine (400 mg/kg) was administered orally. After 8 h, 24 h, 3 days, 7 days, and 14 days, groups of two t...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-009-1611-x
更新日期:2009-11-01 00:00:00
abstract::Gnathiid isopods are marine ectoparasites that feed on the blood of fishes that have been implicated as vectors of blood parasites, with transmission possibly occurring through biting during their parasitic life-stages, or through ingestion by fishes. However, evidence for their role as vectors is limited, reflecting ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-020-06676-6
更新日期:2020-06-01 00:00:00
abstract::Chagas disease, caused by the protozoan Trypanosoma cruzi, is considered to be a multifactorial disease associated with host and parasite genetics, which influence clinical aspects of the disease and other host conditions. In order to understand better the evolution of the disease, this study intended to evaluation of...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-018-5969-5
更新日期:2018-09-01 00:00:00
abstract::Taenia species of domestic dogs can cause cysticercosis and coenurosis in a wide range of intermediate hosts including humans. Most taeniids of dogs are globally distributed, but some wildlife-transmitted species can be specific for certain regions. Generally, little information exists on the species composition and f...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-020-06793-2
更新日期:2020-09-01 00:00:00
abstract::Naturally occurring bithyniid snails, Bithynia siamensis goniomphalos (Prosobranchia: Bithyniidae), and their intermediate hosts were sampled from Khammouane Province, the Lao People's Democratic Republic, and the prevalence of the carcinogenic human liver fluke, Opisthorchis viverrini, was examined. The presence of O...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-010-2140-3
更新日期:2011-04-01 00:00:00
abstract::We examined four species of Plectropomus Oken, 1817 (Serranidae: Epinephelinae), Plectropomus areolatus (Rüppell), Plectropomus laevis (Lacepède), Plectropomus leopardus (Lacepède) and Plectropomus maculatus (Bloch) from sites off Heron Island and Lizard Island on the Great Barrier Reef, Australia (GBR), and the Gambi...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3423-2
更新日期:2013-07-01 00:00:00
abstract::Mosquito adults usually need to ingest sugar from nectar host plants to sustain their metabolic needs. Mosquitoes could be differentially attracted by various flowering plant species, and the volatiles were thought to be important factors attributed to the differential attractiveness. However, whether mosquitoes' pref...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-017-5664-y
更新日期:2018-01-01 00:00:00
abstract::Coccidia (Chromista: Miozoa: Eimeriidae) of columbiform birds (Aves: Columbiformes) have been described since the end of the nineteenth century; however, some of these descriptions were poorly detailed or inconclusive. In this sense, the current work makes a detailed taxonomic revision reconsidering and organizing 18 ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-019-06514-4
更新日期:2020-01-01 00:00:00
abstract::In this study, the larvicidal activity of an enriched fraction of the major lipophilic phenolic compounds from Hypericum carinatum Griseb. (Clusiaceae) was investigated against larvae of Aedes aegypti (Diptera: Culicidae), the main vector of dengue virus in Brazil. The larval mortality rate ranged 37.33 to 72.00 % at ...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-013-3401-8
更新日期:2013-06-01 00:00:00
abstract::Among the topics related to invasion science, the least studied are parasite co-introduction and spillback. This leads to an uncertainty in invasion ecology theories and applications to management. Therefore, the present study brings a systematic review of published information on the metazoan parasite fauna of Microp...
journal_title:Parasitology research
pub_type: 杂志文章,评审
doi:10.1007/s00436-018-5876-9
更新日期:2018-06-01 00:00:00
abstract::Hepatozoon canis is a tick-borne pathogen of canids, which is distributed worldwide. However, very little is known about this protozoan parasite in Pakistan. This study provides the first molecular evidence of H. canis from farm dogs from three agro-ecological zones of Punjab, Pakistan. A conventional PCR targeting th...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-018-5790-1
更新日期:2018-04-01 00:00:00
abstract::The electron microscopic investigation of the anterior part of the infective third-stage juvenile of Onchocerca volvulus provides first insights into the structure of the excretory system of this developmental stage of the parasite. The most anterior part of this system consists of a cell process of the syncytial excr...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/BF00931502
更新日期:1995-01-01 00:00:00
abstract::NADH-ubiquinone oxidoreductase activity is present in mitochondrial lysates of Phytomonas serpens. Rotenone at 2-10 microM inhibited the activity 50-75%, indicating that it belongs to respiratory complex I. The activity was also inhibited 50-60% in the presence of 10-30 nM atovaquone suggesting that inhibition of comp...
journal_title:Parasitology research
pub_type: 杂志文章
doi:10.1007/s00436-003-1058-4
更新日期:2004-03-01 00:00:00